한국인 환자에서 Bravo 식도 pH 검사의 시행과 안전성

조유경 ( Yu Kyung Cho ),최명규 ( Myung Gyu Choi ),장재혁 ( Jae Hyuck Chang ),남관우 ( Kwan Woo Nam ),권정현 ( Jung Hyun Kwon ),서정필 ( Jung Pil Suh ),백창렬 ( Chang Nyol Paik ),박재명 ( Jae Myung Park ),이인석 ( In Seok Lee ) 대한소화기기능성질환·운동학회 2007 Journal of Neurogastroenterology and Motility (JNM Vol.13 No.2

목적 : 무선 Bravo 식도 pH 검사는 서구에서 위식도역류질환의 진단과 치료에 신뢰성이 높고 시행 가능한 검사로 알려져 있다. 본 연구에서는 한국인 환자에서 Bravo 식도 pH 검사의 실행성과 안전성을 알아보고자 하였다. 대상 및 방법 : 72명(남:여=37:35, 44±13세)에서 Bravo pH 검사를 시행하였다. 69명은 위식도역류질환의 진단목적으로 검사를 하였고 3명은 PPI 치료에 반응이 없는 위식도역류질환 환자였다. 62명은 48 시간 검사를, 10명은 24 시간 검사를 시행하였다. 결과 : 1명을 제외한 모든 환자에서 한번에 캡슐부착에 성공하였다(부착률 99%). 64명(89%)에서 최소 24시간 이상 pH 데이터를 얻었다(데이터 수신이상 3명, 부적절한 위치 부착 2명, 24 시간 내 조기탈락 3명). 2일 중 하루만 비정상 산 노출 또는 증상지수 양성인 환자는 55명 중 16명으로, 48시간 검사시 24시간 검사를 하였을 때보다 추가적으로 16%의 환자가 위식도역류질환으로 진단되었다. 93%의 환자는 검사로 인해 일상생활이 약간 또는 전혀 방해되지 않았다고 하였다. 심한 가슴통증을 호소한 4명에서는 캡슐부착부에서 궤양이 발견되었으나 보존 치료로 호전되었다. 결론 : Bravo 식도 pH 검사는 비교적 안전하게 시행 가능한 검사이며, 48시간 Bravo 식도 pH 검사는 24시간 검사에 비해 위식도역류질환의 진단율을 높인다. Background/Aims: The wireless Bravo esophageal pH monitoring has been reported to be a reliable and tolerable method in patients with gastroesophageal reflux disease (GERD) in Western countries. The aim of this study was to assess the performance and safety of the Bravo pH monitoring in Korean patients. Methods: Seventy two patients (M:F=37:35, 44±13 years) undergone 48-hour or 24-hour Bravo pH monitoring to diagnose GERD or to evaluate responses to proton pump inhibitor. Forty eight-hour monitoring was done in 62 patients and 24-hour monitoring was done in 10 patients. Results: The attachment rate of capsule was 99%. Minimum 24-hour pH data were obtained from 64 patients (89%) (poor data reception in 3 patients, early capsule detachment before 24 hours in 3 patients, inappropriate capsule attachment in 2 patients). Compared with first 24-hour data alone, 48-hour data showed 16% more patients with GERD. Ninety three percent of patients answered that their usual activities were slightly disturbed or not disturbed. In four patients who complained severe retrosternal pain after capsule insertion, endoscopy revealed contact ulcer around the capsule. However, their symptoms regressed with conservative treatment. Conclusions: The Bravo pH monitoring is safe and tolerable in Korean patients. Extending recording time to 48-hours with the wireless pH monitoring increases the likelihood of diagnosing GERD. (Kor J Neurogastroenterol Motil 2007;13:111-117)

우리나라 벼 품종개발 변천사 및 성과

조영찬(Young-Chan Cho),백만기(Man-Kee Baek),박현수(Hyun-Su Park),조준현(Jun-Hyun Cho),안억근(Eok-Keun Ahn),서정필(Jung-Pil Suh),정지웅(Ji-Ung Jeung),이종희(Jong-Hee Lee),원용재(Yong-Jae Won),송유천(Yoo-Chun Song),정응기(Eung-Gi Jeong 한국육종학회 2020 한국육종학회지 Vol.52 No.S

Rice research in Korea during the past 100 years has gone through tremendous changes and improvements as the country underwent a turbulent history of transformation. Full-scale R&D modernization began in the 1970s, when the government focused policy on achieving self-sufficiency in rice in order to establish the foundation for national economic growth. A major landmark was reached by the development of the rice variety “Tongil” and its cultivation technology, which was at the core of the unprecedented Korean “Green Revolution”. Since achieving self-sufficiency in rice, the breeding goal of Korea moved from increasing yield to improving grain quality as more consumers began to seek high quality food products in the 1980s. This change led to the establishment of the high quality rice breeding platform for enhancing the global competitiveness of Korean rice to cope with the opening of domestic rice market in the 2000s. Currently, the major breeding goals in rice are developing premium quality cultivars for table rice and specialized cultivars for boosting processed food industry. To date, the National Institute of Crop Science has released a total of 300 rice cultivars, including 202 table rice and 98 specialized usage cultivars. Diverse technologies have been developed and utilized for breeding new rice cultivars to meet changing needs. In the next 100 years of rice breeding, the convergence of traditional crop improvement technologies and the new breeding technologies utilizing recent advances in biotechnology will play a crucial role in enhancing breeding efficiency.

가로변 미디어폴이 보행만족도에 미치는 영향분석

조정필(Jeong-Phil Cho),박태원(Tae-Won Park) 한국콘텐츠학회 2014 한국콘텐츠학회논문지 Vol.14 No.7

본 연구는 서울시 강남구 U-street에 설치된 L.E.D 미디어 폴(Media pole)이라는 통합형 가로시설물이 보행 만족도에 어떠한 영향을 미치는지 분석하는 것이 주요 목적이다. 이를 위해 가로시설물로서 미디어 폴의 구성요소를 보행자 관점에서 탐색적으로 살펴보고 이를 바탕으로 요인분석을 실시하였다. 요인분석을 통해 제1요인은 ‘심미·상징성’요인으로 명명하였고, 제2요인은 ‘형태·조형성’, 제3요인은 ‘접근·연속성’으로 분석하였다. 제4요인은 ‘감각·전달성’, 제5요인은 ‘정보·매체성’으로 명명하였다. 요인분석은 이용자 관점에서 사례대상지 보행자에 대한 행태관찰과 심층면접(In-depth Interview)을 실시하였고, 33개 예비변수를 도출하였다. 도출된 예비요인을 전문가 F.G.I(Focus Group Interview)를 통해 최종적으로 요인분석에서 사용할 20개 예비변수를 선정하였다. 요인분석을 통해 선정된 5개의 독립변수와 보행자의 만족도를 종속변수로 다중회귀분석을 실시한 결과 강남대로 U-street에 설치된 미디어 폴이 보행자의 보행만족도에 미치는 영향 중 통계학적 유의미한 영향요소는 ‘심미·상징성’요인으로 분석되었다. U-street에서 미디어 폴은 보행자에게 심미적 감성과 상징성으로 새로운 보행체험에 기여하고 있는 것으로 판단된다. 향후 이용자 편의성을 기반으로한 정보매체로서의 접근성을 강화하고 활용 가능한 콘텐츠 다양화를 유도해야할 것이다. IT 기반형 멀티미디어 매체인 미디어폴은 융합하는 가로환경과 융합하여 보행자에게 새로운 경험을 제공하여 보행활성화에 새로운 수단으로서의 가능성을 시사하고 있다. The purpose of this study is to observe the effects of road facilities that have adopted digital media such as total road facility called L.E.D media pole installed on U-street, Gangnam-gu on the pedestrians’ satisfaction. Through the study, we would like to improve the brand competitiveness, increase the revisiting decision factors and suggest the fundamental development direction for the digital media road facilities on the typical pedestrian road, Gangnam street. The three factors from the studies came out to be spatial component, design component, and functional component. In order to analyze the factors, the pedestrians’ behaviors were observed through a direct survey which provided 35 reserved factors. Also, the preliminary factors derived through survey questionnaires were revised by experts which compressed the result into 20 factors. The result of the regression analisis states that the Factor of the spatial component is the statistically significant factor among the five elicited factors of the effect of the media pole on the pedestrian satisfaction. U-street’s media pole provides the comfortable and various contents and application methods and will provide the new perspective on the purpose of pedestrians by new experience that is based on digital technology.

NO의 선택적 촉매 환원반응에 대한 Co/ZSM-5의 소성조건에 따른 안정성에 관한 연구

박석준,이철위,정필조,Park, Seok Joon,Lee, Chul Wee,Chong, Paul Joe 대한화학회 1997 대한화학회지 Vol.41 No.6

초장립종 벼를 이용한 입형 관련 QTL 분석 및 국내 벼 품종 입형 개선 연구

김석만,박현수,이창민,백만기,조영찬,서정필,정오영,Kim, Suk-Man,Park, Hyun-Su,Lee, Chang-Min,Baek, Man-Kee,Cho, Young-Chan,Suh, Jung-Pil,Jeong, Oh-Young 한국작물학회 2020 한국작물학회지 Vol.65 No.4

Rice grain shape is one of the key components of grain yield and market value. An understanding of the genetic basis of the variation in grain shape could be used to improve grain shape. In this study, we developed a total of 265 F₂ individuals derived from a cross between japonica cultivars (Josaeng-jado and Langi) and used this population for quantitative trait locus (QLT) analysis. Correlation analysis was performed to identify relationships between grain traits (GL: grain length, GW: grain width, L/W: ratio of length to width, TGW: 1,000 grain weight). The grain shape was positively correlated with GL and TGW, and negatively correlated with GW. In QTL analysis associated with grain shape, one QTL for GL, qGL5, detected on chromosome 5, explained 20.3% of the phenotypic variation (PV), while two QTLs, qGW5 (PV=36.1) and qGW7 (PV=26.1), for GW were identified on chromosomes 5 and 7, respectively. Evaluation of the effects of each of the QTLs on the grain shape in the population showed a significant difference in the grain size in positive lines compared with the lines without the QTLs. According to the QTL combination of the allelic-types, the grain shape of the tested lines varied from semi-round type to long spindle-shaped type. The results of this study extend our knowledge about the genetic pool governing the diversity of grain shape in japonica cultivars and could be used to improve the grain shape of this species through marker-assisted selective breeding in Korea.

산소분위기에서 프로판에 의한 질소산화물 제거용 선택적 Co - ZSM -5 촉매의 공존양이온효과

박석준,이철위,스타키프,김영상,정필조 ( S . - J . Park,C . W . Lee,A . Yu . Stakheev,Y . - S . Kim,P . J . Chong ) 한국화학공학회 1995 화학공학의이론과응용 Vol.1 No.1

호남평야지 재배시기별 조생종 벼 품종의 품질 및 호화점도 특성 분석

박현수(Hyun-Su Park),백만기(Man-Kee Baek),이창민(Chang-Min Lee),김석만(Suk-Man Kim),서정필(Jung-Pil Suh),정오영(O-Young Jeong),조영찬(Young-Chan Cho) 한국육종학회 2021 한국육종학회지 Vol.53 No.1

Early maturing rice is widely utilized to diversify cropping systems in the Honam Plain, Korea. It is based on the principle ofa short growth duration. There is concern regarding quality deterioration of early maturing rice owing to the high temperature during theripening stage as compared to that for mid and mid-late maturing rice. This study was conducted to analyze six pasting property-related andeight quality traits of six early maturing rice varieties (Jopyeong, Odae, Unkwang, Haedamssal, Jinkwang, and Haedeul) on early, ordinary,and late cultivations, and to interpret the relationships between genotypes and environments. As the cultivation time increased, the ratio ofhead rice (HR) and glossiness of cooked rice (Toyo value, TY) increased. The cumulative mean temperature of the ripening stage showeda strong negative correlation with HR and TY at all cultivation times. Pasting temperature, peak viscosity (PV), trough viscosity, final viscosity,and breakdown (BD) decreased, whereas setback (SB) increased as the cultivation time was delayed. Pasting properties were affected moreby climate conditions in the ripening stage than during the growth stage. Additive main effects and multiplicative interaction analysis revealedthat pasting property-related and quality traits were affected more by environment than genotype. Jinkwang and Haedamssal in early and ordinarycultivation and Jinkwang and Haedeul in late cultivation exhibited higher HR and TY and a lower protein content. They also showed higherPV and BD and lower SB, which are characteristics of good eating quality japonica rice. Jinkwang, Haedamssal, and Haedeul are premium-quality,early maturing rice varieties that were recently developed. The cultivation of these varieties could improve the grain quality of early maturingrice at high temperatures during the ripening stage in the Honam Plain.

LED 미디어 파사드가 보행자 야간 경관 지각에 미치는 영향 분석

한연오(Han, Yeon Oh),조정필(Cho, Jeong Phil),박태원(Park Tae Won) 한국지역개발학회 2014 한국지역개발학회 세미나 논문집 Vol.2014 No.1

As the modern city s interest in night atmosphere and the activities increases dramatically, the importance of the landscape of urban buildings is also increasing. The interest in urban landscape is focusing more on the after sunset hour rather than daytime due to the extended activity hours and the change in life pattern of the urban citizens. The purpose of the study is to analyze the effect of the sense of place developed by LED Media-Facade on pedestrian s feel about the landscape. Hence, the Seoul Square Building was chosen as the main research case target area. Located across the gateway into Seoul, Seoul station plaza, Daewoo Building was named Seoul Square after Morgan Stanley became the owner. 42,000 LED Pixels were installed in Media-Facade structure on the front surface of the building, making it the largest media-canvas in the world. LED media-facade technology is one of the technologies that is specialized to construct the urban area which brings a paradigm to urban areas, enabling the new urban design. This allows the creation of new form of city scenary in the urban area satisfying the pedestrians scenic experience. Also, this would increase the building s identity and awareness which will lead to increase in the brand and property value of the building.

내병성 자포니카 벼 계통 육성과 저항성 유전자 집적효과

김우재,백만기,박현수,이건미,이창민,김석만,조영찬,서정필,정오영,Kim, Woo-Jae,Baek, Man-Kee,Park, Hyeon-Su,Lee, Geon-Mi,Lee, Chang-Min,Kim, Seok-Man,Cho, Young-Chan,Seo, Jeong-Phil,Jeong, O-Young 한국작물학회 2020 한국작물학회지 Vol.65 No.4

This study was carried out to develop a resistant variety against the K3a race of bacterial blight, Xanthomonas oryzae pv. oryzae, through expansion and pyramiding of resistance genes. To develop an elite bacterial blight-resistant cultivar, the breeding process and bacterial blight resistance reactions in advanced backcross lines (ABLs) were analyzed. ABLs21 which contain Xa3 and Xa21, were developed by double backcrossing japonica cultivar Hwanggeumnuri, which has bacterial blight resistant Xa3 gene, and indica variety IRBB21, which havs Xa21 gene, followed by disease resistance bioassay and marker-assisted selection. The resistance genes of ABLs21 were amplified by PCR with the molecular markers 9643.T4 (Xa3) and U1/I1 (Xa21). Hwanggeumnuri and IRBB3 showed resistance reactions against K1, K2, and K3 races, and a susceptible reaction against K3a, K4, and K5 races. IRBB21 showed resistance reactions against K2, K3, K3a, K4 and K5 races, and a susceptible reaction against K1 race. Hwanggeumnuri showed susceptible reactions at the seedling, tillering and adult stages (all stages), whereas ABL21-1 showed moderate resistance at the tillering stage. ABL21-1 showed stable resistance against 18 isolates of K3a race, and the lesion length was shorter than that of the donor parents. In cluster analysis, the HB4032 isolate showed the highest pathogenicity among the 18 isolates. The molecular marker polymorphisms and average substituted chromosome segment lengths of ABLs21 were 63.2 % and 86.1 cM, respectively. Insertion of the donor chromosomal segments occurred in the predicted region of the Xa21 gene of ABLs21.

연구발표논문초록 ( 공업화학 (Ⅱ) ) : 광산 용출에 의한 Builder 급 Zeolite 의 개량 점토법

이광석 (정),서정권 (정),이정민 (정),정필조 (정),박춘희 (정) ( K . S . Lee,J . K . Suh,J . M . Lee,P . J . Chong,C . H . Park ) 한국화학공학회 1988 춘계학술발표회 Vol.- No.-