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      • SCOPUSKCI등재

        제왕절개수술에서 저혈압 예방을 위한 수액의 비교 관찰 : 제 1 보:척수마취

        심재철,김완식,박동호,황영희,김흥대,김지영,차영덕,서병태 대한마취과학회 1982 Korean Journal of Anesthesiology Vol.15 No.3

        Rheomacrodex-D 10% W/V in dextrose (500 ml) was prophylactically infused before anesthesia over 15 to 20 minutes to prevent hypotension during spinal anesthesia in 20 patients undergoing elective Casarean section. Apgar scores and the incidence and severity of hypotension were compared to results obtained in 20 patients who were given 500 ml of Hartmann's solution. The results were as follows; 1) Mean arterial pressure decreased up to 20 torr from control values in patients hydrated with Hartman's solution and also changed significantly in patients given Rheomacrodex-D (p<0.05). 2) The incidence and severity of hypotension at 10 minutes, and 15 minutes, and 15 minutes after spinal anesthesia (p<0.05) was significantly less in patients given Rheomacrodex-D than in patients hydrated with Hartmann's solution 3) The Apgar scores, both at 1 minute and 5 minutes, were significantly higher (p<0.05, p<0.005) in infants born of mothers given Rheomacrodex-D than in infants whose mothers were given Hartmann's solution. 4) The cases of hypotension defined as a descrease in systolic arterial pressure lower than 100 torr or a decrease in mean arterial pressure to 25% from control values were 12 cases in 20 patients hydrated with Hartmann's solution and 6 cases in 20 patients given Rheomacrodex-D.

      • SCOPUSKCI등재
      • KCI등재후보

        중등도 및 중증고혈압에서 Nifedipine 설하투여의 강압효과에 관한 연구

        김영훈,서순규,최인석,김열홍,안희권,심완주,노영무 대한내과학회 1986 대한내과학회지 Vol.31 No.5

        In order to assess the efficacy of sublingual nifedipine in the acute treatment of moderate to severe hypertension, a single blind test was done in 30 patients, 10 males and 20 females, aged 40 to 76 years, with moderate to severe hypertension. The patients with mean sitting blood pressure(BP) of more than J40 mmHg received sublingual placebo, and BP and pulse rate(PR) were measured in sitting position 10,20 and 30 minutes after the sublingual placebo was given. The patients with post-placebo 30 minutes sitting mean BP of less than 13pmmHg were excluded from the study. The placebo treatment period was followed by the administration of 10mg of sublingual nifedipine, and BP and PR were measured 10,20,30 and 45 minutes after nifedipine was given. BP decreased with placebo treatment(p$lt;0. 01 by paired t-test, preplacebo vs. post-placebo 30 minutes). With sublingual nifedipine BP started to fall in 10 minutes and reached the lowest levels in 30 or 45 minu1es. The systolic BP decreased from 198.0±21.4mmHg to 159±20.4mmHg, diastolic BP from 122.5±13.0 mmHg to 103.2±14.4 mmHg and mean from 147.7±13.4 mmHg to 121.7±14.8 mmHg 45minutes after nifedipine(p$lt;0.01 by paired t-test). The average fall in systolic BP/diastolic BP/mean BP 45 minutes after nifedipine was 39/19/26 mmHg(p$lt;0. 001, by paired t-test). The maximal fall in systolic BP correlated better with pretreatment value(r=0.42) than the maximal fall in diastolic pressure(r=0.21), PR increased from 79±12 to 87±11/minute with nifedipine(p$lt;0.001, by paired t-test). Side effects were mild facial flushing(16.7%) and palpitation (3.3%). The findings suggest that a dose of 10mg of sublingual nifedipine is a simple, effective and safe method for the acute treatment of moderate to severe hypertension and can be used as a non-injecting alternative agent for the treatment of hypertensive emergency.

      • SCOPUSKCI등재

        소아마취의 임상통계학적 고찰

        김완식,박동호,황영희,김흥대,안기량,석민호,김지영,장경덕,서병태 대한마취과학회 1982 Korean Journal of Anesthesiology Vol.15 No.1

        Midazolam maleate, a water soluble banzodiazepine unlike diazepam, was synthetized by Walser and Fryer in 1975. In order to ealuate the effectiveness as an induction agent for general anesthesia, 22 elective surgical patients belonging to ASA classification 1 and 2 were selected. And ten patients (male 7, female 3, average 33.5 years old) were induced with midazolam maleate 0.2mg/kg and twelve patients (mdale 7, female 5, average 32.5 years old) with diazepam 0.3mg/kg. The results were summarized as follows. 1) Anesthesia was induced in all of midazolam group by one intravenous injection, but only 6 patients of diazepam group could induced by one injection and the other 6 patients needed 2 or more injections. 2) The changes of blood pressure and pulse rate after induction and intubation were almost similar in the two groups, but greater individual variation was seen in diazepam group. 3) A buring sensation following intravenous injection was noted in 11 cases of diazepam group, but none in midazolam group and no phlebitis in either group. From the above results, diazepam and midazolam are almost similar in nature but midazolam is definitely effective as an induction agent and has less side effects. Therefore midazolam maleate is regarded as a more effective agent than diazepam as an induction for general anesthesia.

      • SCOPUSKCI등재

        B . C . G 접종후 속발된 심상성 낭창양 (狼瘡樣) 반응의 1 예

        송준영,서정희 대한피부과학회 1979 大韓皮膚科學會誌 Vol.17 No.1

        B.C.G. is a living attenuated vaccine which produces resistance to tuberculous infection. Until now, several million persons were vaccinated with B.C.G., the rnajority being between 7 and 14 years of age. A very small number of general fatal reaction have been reported but from an epidemiological view point this does not; serions dirninish. the importance of B.C.G. Vaccination in the fight against tubereulosis. Dermatological complication of R.C.G. are rarely seen. Specific reactions attributed to the Vaccination were excessive lymphadenitis, scrofuloderma like, Iupus vuIgaria like, lichen nitidus lesion and tuberculid type lesion. Non specific reactions include toxicoderma hemorrhagica, urticaria, erythema multiform, erythema nodosum and granuloma anulare. Literature was briefly reviewed comparision of clinical and histological findings with this particular case. We are going to report one case of lupus vulgaris like reaction after B.C.G. Vaccination.

      • KCI등재후보

        소비자 관능검사 결과에 영향을 미치는 인자

        신용국,백승천,김수광,서동순 한국유가공기술과학회 1998 Journal of Dairy Science and Biotechnology (JMSB) Vol.16 No.2

        The purpose of consumer sensory tests is to assess the personal response by current or potential customers of a product or specific product characteristics. There are several sources of bias in obtaining consumer response than often lead to misleading results. These biases include the situational variables of the testing environment, the products and the subjects. This paper discusses the sources of bias in consumer testing, need to be controlled when conducting consumer test.

      • 저밀도 폴리에틸렌의 전기전도에 미치는 실리콘유의 영향

        서광석,이창용,강창균 고려대학교 공학기술연구소 1991 고려대학교 생산기술연구소 생기연논문집 Vol.27 No.1

        Electrical conduction characteristics of low density polyethylene with a silicon-oil layer at the surface have been investigated at medium fields ranging from about 75 to 650 ㎸/㎝ over the temperature range of 20 to 100℃. The conduction current of polyethylene increases exponentially with the electric field and gets higher as the temperature increases. The observed conduction behavior was explained in term of the SCLC and tunneling effect. Activation energy ranges from 0.54 to 0.44 eV over the field range of 90∼450 ㎸/㎝ and the charge mobility was estimated from a Child law to be in the order of 10^(-16)∼10^(-14)㎡/V·s. Silicone oil layer modifies the conduction behaviors in polyethylene. Major changes are (1) an increase in conduction currents, (2) a suppression in a rate of change of conduction currents, and (3) a decrease in activation energy.

      • KCI등재

        BLT (Bi3.25La0.75Ti3O12) 박막의 결정립 배향성이 잔류 분극과 누설 전류에 미치는 영향

        서주형,오상호,박찬향 대한금속재료학회(대한금속학회) 2001 대한금속·재료학회지 Vol.39 No.11

        Effect of grain orientation on the electrical polarization and leakage current characteristics of Bi_(3.25)La_(0.75)Ti₃O_(12) (BLT) thin films was investigated in terms of c-axis off alignment. The c-axis epitaxial and various c-axis off aligned BLT films have been successfully grown by using different electrode materials (Pt and SrRuO₃) and heat-treatments. In order to evaluate the crystallinity and the film texture of various c-axis off-aligned BLT thin films, X-ray diffraction (XRD) and transmission electron microscopy (TEM) were carried out. BLT thin film grown on the SrRuO₃/SrTiO₃ (100) substrate revealed that its c-axis aligned completely parallel to the substrate normal, by developing cube-on-cube epitaxial relathionship with underlying SrRuO₃ film. The corresponding P-E curve showed nearly paraelectric property. The polycrystalline (117) and (014) oriented BLT films grown in this study were shown that their c-axis off alignment about growth direction increased by amount more than 50°. As the degree of c-axis off-alignment was increased, remanent polarization was increased due to the anisotropic polarization characteristic of BLT film, however, the surface roughness of BLT films was increased and it resulted in degraded leakage current characteristic. Therefore, grain orientation of BLT thin films is a crucial factor controlling the polarization properties and leakage current characteristics.

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