김제 지역 한우 송아지의 크립토스포리듐, 지알디아 발생 현황

이한경 ( Han-kyoung Lee ),소경민 ( Kyoung-min So ),오상익 ( Sang-ik Oh ),노재희 ( Jae-hee Roh ),김미숙 ( Mi-suk Kim ),강명금 ( Myoung-geum Kang ),정숙한 ( Suk-han Jung ),정영훈 ( Young-hun Jung ),조아라 ( Ara Cho ),이한규 ( Han Gy 한국동물위생학회(구 한국가축위생학회) 2021 韓國家畜衛生學會誌 Vol.44 No.2

This study was performed to identify the prevalence of cryptosporidiosis and giardiasis in diarrhea feces of Korean native calves raised in Gimje, Jeollabuk-do, with a rapid diagnostic kit. The prevalence of both diseases were classified according to the age of calf, season of sampling period, and sampled farm where diarrheic calf is commonly observed. In diarrhea feces of 431 calves, cryptosporidiosis had a high incidence rate between 1 and 3 weeks of age, whereas giardiasis showed a high incidence between 4 and 6 weeks of age. It is thought that the incidence of protozoan diseases is markedly influenced by the calf’s postnatal age. Regarding with the sampling season, the prevalence of cryptosporidiosis and giardiasis in calves was significantly higher in spring and summer than in autumn and winter (P<0.05). Among the sampled farms where both diseases are commonly observed, cryptosporidiosis was more frequently detected than giardiasis in calves. Particularly, in farms where cryptosporidiosis is common, it tends to be a disease that is difficult to eradicate as it occurs continuously throughout the year. Hygiene management such as regular cleaning and disinfection of the livestock and the surrounding environments is considered necessary to reduce and prevent damage from these protozoal diseases.

완전 도재관을 위한 지대치 형성시 변연 형태에 따른 응력 분포의 유한요소법적 비교

한상현,조정현,이은정,정숙인,오남식,Han, Sang-Hyun,Cho, Jung-Hyeon,Lee, En-Jung,Jeong, Suk-In,Oh, Nam-Sik 대한치과보철학회 2008 대한치과보철학회지 Vol.46 No.1

현대 치의학에서는 환자의 심미적 만족을 충족시키기 위한 지속적인 관심으로 완전 도재관의 발전을 가져왔다. 최근의 연구 결과들은 완전 도재관의 물리적 성질과 마모 저항성, 색조의 안정성 등을 보고하고 있다. 이와 같이 여러 장점이 많음에도 불구하고 아직 파절에 대한 저항성에는 많은 의문점을 내포하고 있다. 구강 내에서 기능적인 교합력은 수복물의 변연에 응력을 주게된다. 이러한 응력은 주변 조직으로 잘 분산되어져야 하는데, 수복물의 변연 형태에 따라 다른 양상을 보여주게 된다. 변연 형태는 수복물의 부피와 모양, 그리고 변연에서의 적합도에도 영향을 주게 된다. 본 연구에서는 완전 도재관에서의 변연 형태에 따른 응력 분포를 3차원 유한 요소 분석법을 이용하여 조사하였다. 상악 중절치가 기본 모델로 사용되었고, 완전 도재관을 재현하였다. 변연 형태로는 $90^{\circ}$ shoulder, $110^{\circ}$ shoulder, $135^{\circ}$ shoulder형태를 부여하고, 100N의 힘을 치축에 $45^{\circ}$ 방향으로 가하였다. 그 결과 도재 내부의 응력 분포는 $90^{\circ}$, $110^{\circ}$ 모델에 비해 변연 각도가 $135^{\circ}$인 모델의 경우가 응력의 분포가 고르게 나타났다. 그러나 변연에서는 $90^{\circ}$와 $110^{\circ}$ 모델의 응력보다 조금 더 집중되었다. $90^{\circ}$와 $110^{\circ}$ 모델의 비교시는 대체로 비슷했다. 알루미나 코아 내부의 응력 분포에서도 또한 $135^{\circ}$인 모델이 $90^{\circ}$와 $110^{\circ}$ 모델의 응력분포보다 더 잘 분포되었다. $90^{\circ}$와 $110^{\circ}$ 모델의 비교시는 $110^{\circ}$가 $90^{\circ}$ 모델에 비해 더 좋은 응력분포를 보였다. 알루미나 코아와 접착제 사이의 계면에서는 응력이 변연으로 갈수록 감소하고, 알루미나 코아와 도재 사이의 계면에서는 변연으로 갈수록 응력이 점차 증가하였다. $135^{\circ}$ shoulder는 고른 응력분포임에도 변연에서의 응력 집중이 나타나므로 완전 도재관의 변연으로는 적절하지 못하며, $90^{\circ}$ shoulder보다 상대적으로 좋은 응력분포와 변연 형성의 용이성이 우세한 $110^{\circ}$ shoulder가 완전 도재관의 변연에 추천될 수 있겠다. Statement of problem: Over the past decade, increased demand for esthetically pleasing restorations has led to the development of all-ceramic systems. Recent reports suggest that the all-ceramic crowns have excellent physical properties, wear resistance, and color stability. In addition, numerous ceramics have excellent biocompatibility, a natural appearance, and improved physical bonding with resin composite luting agents. However, the brittle nature of ceramics has been a major factor in their restriction for universal usage. Functional occlusal loading can generate stress in the luting agent, and the stress distribution may be affected by the marginal geometry at the finish line. Tooth preparation for fixed prosthodontics requires a decision regarding the marginal configuration. The design dictates the shape and bulk of the all ceramic crowns and influences the fit at the margin. Purpose: The purpose of this study was to evaluate the stress distribution within marginal configurations of all- ceramic crowns (90-degree shoulder, 110-degree shoulder, 135-degree shoulder). Material and methods: The force is applied from a direction of 45 degrees to the vertical tooth axis. Three-dimensional finite element analysis was selected to determine stress levels and distributions. Results and conclusion: The result of stress level for the shoulder marginal configuration was more effective on stress distribution at 135-degree shoulder margin. But the stresses concentrated around at 135-degree shoulder margin. The stress decreased apically at the surface between cements and alumina core, and increased apically at the surface between alumina core and veneering porcelain.

작약꽃을 이용한 미백 및 항산화 효과 분석

정연옥(Yen Ok Jung),박노복(Nou Bog Park),정숙진(Suk Jin Jung),곽준수(Joon Soo Kwak),한종현(Jong Hyun Han) 한의병리학회 2010 동의생리병리학회지 Vol.24 No.3

30,000rpm 고속 주축의 열특성 분석

임정숙(Jeong Suk Lim),유기한(Ki Han Yu),정원지(Won Jee Chung),김수태(Soo Tae Kim),이정환(Jung Hwan Lee),이춘만(Choon Man Lee) Korean Society for Precision Engineering 2009 한국정밀공학회지 Vol.26 No.7

농흉에서 전산화 단층촬영의 의의

허정숙 ( Jeong Suk Heo ),권오영 ( Oh Yong Kwun ),손정호 ( Jeong Ho Sohn ),최원일 ( Won Il Choi ),황재석 ( Jae Seok Hwang ),한승범 ( Seung Beom Han ),전영준 ( Young June Jean ),김정식 ( Jung Sik Kim ) 대한결핵 및 호흡기학회 1994 Tuberculosis and Respiratory Diseases Vol.41 No.4

성인 여성의 체중조절을 위한 영양

김미연(Mi Yeon Kim),한서영(Seo Young Han),정정희(Jeong Hee Jeong),김성희(Sung Hee Kim),이진경(Jin Kyoung Lee),박은숙(Eun Suk Park),장선화(Xian Hua Zhang),서정숙(Jung Sook Seo) 대한지역사회영양학회 2009 대한지역사회영양학회지 Vol.14 No.2

This study was conducted to investigate the effectiveness of a nutrition and exercise education program on weight control of adult women. The subjects of this study were 28 adult women aged 20-59 years residing in the Daegu area. The nutrition-exercise educational period was 12 weeks. The collected data consisted of items on general characteristics, anthropometric data, blood biochemical values, physical strength data, dietary behavior and nutrition knowledge scores of the subjects. During the 12 weeks of weight control, body mass index (BMI), % of body fat, body fat mass and waist-hip ratio significantly decreased. The level of plasma triglyceride decreased, but not significantly. The level of total cholesterol did not change compared to baseline before the program. After the weight control program, back muscle strength, sit-ups, push-ups, and sit-and-reach tests of the subjects significantly improved. The nutrition knowledge scores of the subjects significantly increased. Therefore, these results suggest that the nutrition-exercise education program may contribute effectively to weight reduction with improvement of physical strength in adult women. (Korean J Community Nutrition 14(2):168~174, 2009)

대식세포에서 지단백 산화에 대한 수용성 Chitinous Compounds의 항산화 효과에 대한 연구

이세희(Lee Se-Hee),박성희(Park Sung-Hee),이용진(Lee Yong-Jin),윤정한(Jung Han Yoon),최연정(Choi Yean Jung),최정숙(Choi Jung-Suk),강영희(Kang Young-Hee) 韓國營養學會 2003 Journal of Nutrition and Health Vol.36 No.9

알코올 대사 효소들의 유전적 다형성이 알코올성 간경변증의 발생에 미치는 영향

이효석,김정룡,윤정환,정숙향,이한주 대한간학회 1998 Clinical and Molecular Hepatology(대한간학회지) Vol.4 No.1

Background/Aims There is considerable variance in individual susceptibility to hepato- toxic effects of ethanol as evidenced by the finding that only about 10-20% of alcoholics develop alcoholic liver cirrhosis. The aims of this study were', 1) to get the data on the genetic polymorphisms of three major ethanol-metabolizing enzymes (ADH, CYP2E1, ALDH) in normal Korean adults, and to search for the specific genotypes influencing alcohol drinking behavior by the comparison of allele frequencies between healthy control group and heavy drinker group with or without liver disease, 2) to investigate the influence of the genetic polymorphisms of these enzymes on the susceptibility to alcoholic liver disease by the comparison of allele frequencies between heavy drinker group without liver disease and alcoholic liver cirrhosis group. Methods - Healthy control group included 53 healthy males in military service without evidence of liver disease or alcoholism. Heavy drinker group without liver cirrhosis included 29 males who had been drinking 80g or more of alcohol daily for more than ten years but did not have any clinical evidence of liver disease. Alcoholic cirrhosis group included 43 male patients who had drunk 80g or more of alcohol daily for more than ten years and had clinical evidences of overt cirrhosis. Subjects with hepatitis B surface antigen or anti-hepatitis C antibody were excluded. Genotypes of the three enzymes were determined by PCR (polymerase chain reaction) and restriction fragment length polymorphism (RFLP) with genomic DNAs extracted from peripheral leukocytes. Results' 1) In healthy Korean males, allele frequency of ADH2*2, ADH3*1, CYP2E1 c2 and ALDH2*2 was 81%, 94%, 30% and 14%, respectively. 2) The absence of ALDH*2Focal nodular hyperplasia (FNH) is a rare, benign hepatic tumor which was usually discovered incidentally by imaging procedure performed for some other reasons. FNH is typically asymptomatic and, it seldom bleeds. There is no evidence to support any relation with primary liver cancer. Accordingly, the preferred management is conservative, and excision is reserved for large symptomatic and complicated lesion, or when the diagnosis remains uncertain. Although many cases of FNH has been described to date in the other countries, only four cases of FNH has been reported in Korean literature. In the present report we describe a 7 cm sized asymptomatic lesion of FNH in a 23-year-old woman, that was disclosed by various kinds of imaging procedure. The left lateral segmentectomy was performed. The mass was firm and showed areas of localized growth of mature hepatocytes and septal fibrosis accompanied with marginal ductal proliferation, consistent with FNH. It also displayed an incomplete stellate architectual configration consisted of a central fibrous scar. (Korean J Hepatol 1997;7:337 343)2 or CYP2E1 c2 allele were significant risk factors for being a heavy drinker (odds ratio,' 0.09, 0.42, respectively). 3) Although it was not associated with the polymorphism of each ethanol-metabolizing enzymes, the susceptibility to alcoholic liver cirrhosis was significantly associated with combined genotypes of ADH2(2*2) & ADH3(1*1)& CYP2E1 B or C. Conclusion- Genetic polymorphisms of ethanol-metabolizing enzyrnes are significantly associated with the suseptability to alcoholic liver disease as well as alcohol drinking behavior. (Korean J Hepatol 1998;8:1 11)

한국인에서의 만성적 궤양을 동반하는 대장염에 대한 임상적 고찰

이풍렬,윤한두,김나영,정숙향,유권,정현채,이효석,윤용범,송인성,최규완,김정룡,최상운 대한내과학회 1990 대한내과학회지 Vol.38 No.3

The purpose of this study is to compare the differences of the symptoms, signs and laboratory findings among colitis with chronic ulceration, such as ulcerative colitis, Behcet's colitis, tuberculous colitis and Crohn's disease in Korea. Were studied in Seoul National University Hospital from August 1982 to Oocober 1988. Forty-two cases of ulcerative colitis, 23 cases of Behcet's colitis, 53 cases of tuberoulous colitis and four cases of Crohn's disease were analyzed in terms of age, sex, symptomatology, laboratory findings and consequence of treatment. 1) The sex ratio of ulcerative colitis, Behcet's, colitis tuberculous colitis and Crohn's disease was 1 : 1.63, 4.74 : 1, 1 : 1. 30, and 3 : 1, respectively, and the mean age was 36.1, 34.3, 33.4, 22.5 years, respectively. 2) The duration of symptoms in tuberculous colitis was significantly shorter than in other diseases. 3) The items of symptoms and signs showed that significant differences were rectal bleeding, diarrhea, weight loss, tenesmus, oral ulcer, skin lesion and genital ulcer. 4) The items of laboratory findings revealed that significant differences were anemia, increased ESR, hypoalbuminemia and the evidenoe of tuberculous lesion on chest X-ray. 5) In view of the anatomical distribution of the lesions, the rectums of all the cases were involved in ulcerative colitis. In most cases of Behcet's colitis and tubercuious colitis, the right colon, including the cecum and the ileum, was involved. In Crohn's disease, the ileum and the jejumum were frequently involved. 6) From a discriminant analysis, we could find several items that differentiated the four diseases. There were rectal bleeding, diarrhea, oral ulcer, hypoalbuminemia and evidence of tuberculosis on chest X ray.

진행성 위암 환자에서 발생한 Cisplatin에 의한 말초신경병증

김창민,박연희,김유철,유성재,김태유,한철주,김종광,이진오,류백렬,김봉석,최성준,정숙향,강윤구 대한소화기학회 2000 대한소화기학회지 Vol.36 No.5

Background/Aims: Since cisplatin was widely used for the treatment of advanced gastric cancer, prevention and management of its side effects have become an important issue. Among the various side effects, neurotoxicity still remains as the major dose-limiting side effect of cisplatin. To investigate the frequency and the prognostic factors of neurotoxicity associated with cisplatin- containing chemotherapy, we performed this retrospective analysis. Methods: We analyzed clinical data of 317 patients with advanced gastric cancer treated with cisplatin-containing (20 mg/m2/day, D1-5 per cycle) chemotherapy in Korea Cancer Center Hospital from 1992 to 1996. Results: Peripheral neuropathy was developed in 44 patients(13.9%; 95% C.I, 10-17.8%): 28 patients in who grade I and 16 patients in who grade II. The incidence of peripheral neuropathy was increased as the cumulative dose of cisplatin increased. Age(p=0.0458) and cumulative dose of cisplatin(p 0.0001) were significant prognostic factors for the development of peripheral neuropathy in multivariate analysis. Conclusions: Peripheral neuropathy was a side effect of cisplatin-containing chemotherapy observed frequently in patients with advanced gastric cancer. Its development was closely related with cumulative cisplatin dose and patient's age. Once peripheral neuropathy developed clinically, it did not improve in most patients even after the administration cisplatin was discontinued.