아밀로오스 함량에 따른 옥테닐호박산 쌀전분의 제조 및 이화학적 특성

정명훈(Myung-Hoon Jung),윤광섭(Kwang-Sup Youn) 한국식품과학회 2012 한국식품과학회지 Vol.44 No.5

The purpose of this study was to investigate the preparation and physicochemical characteristics of noctenylsuccinylated (OSAn) rice starches with different rice amylose contents. Amylose contents of Jinsumi flour and Milyang 261 flour were 15.42 and 20.31%, respectively. After processing by alkali treatment, amylose contents of Jinsumi rice starch and Milyang 261 rice starch were 34.21% and 39.32%, respectively. After OSAn treatment, the degree of substitution and reaction efficiency of Jinsumi starch were higher than those of Milyang 261. The stability of the modified Jinsumi emulsion was higher than that of the Milyang 261 emulsion. Viscosity of the Jinsumi emulsion was higher than that of the Milyang 261 emulsion. When the emulsions were spray dried, modified Jinsumi rice starch showed excellent coating efficiency compared to that of modified Milyang 261 rice starch. Therefore, Jinsumi was more suitable than Milyang 261 to apply for encapsulation as wall materials.

한국형 우울장애 약물치료 알고리듬 2021 (V) : 안전성, 부작용, 동반 신체질환을 고려한 항우울제 선택 및 치료저항성 우울증의 임상적 정의

정명훈(Myung Hun Jung),이정구(Jung Goo Lee),박원명(Won-Myong Bahk),우영섭(Young Sup Woo),왕성민(Sheng-Min Wang),정종현(Jong-Hyun Jeong),김원(Won Kim),심세훈(Se-Hoon Shim),서정석(Jeong Seok Seo),장승호(Seung-Ho Jang),양찬모(Chan-Mo Y 대한신경정신의학회 2021 신경정신의학 Vol.60 No.4

Objectives To revise Korean Medication Algorithm Project for Depressive Disorder 2017 (KMAPDD 2017) guidelines by revising antidepressant choices based on their safety, adverse effects, comorbid physical illnesses, and the clinical definition of treatment-resistant depression (TRD). Methods A 33-item questionnaire comprised of six parts was developed. A 65-expert consensus (65/97, 67.0%) was obtained on pharmacological treatment strategies regarding antidepressant choice with respect to safety, adverse effects, and comorbid physical illnesses. Multiple response sets were subjected to statistical analysis. Results The results obtained showed that first-line pharmacotherapeutic strategies based on various clinical considerations were as follows: mirtazapine (for patients with increased suicidality, Gastrointestinal discomfort, and insomnia), bupropion (for patients with orthostatic hypotension, history of a safety accident, serotonin syndrome, sedation, sexual dysfunction, and weight gain), and escitalopram (for patients with anticholinergic side effects). For patients exhibiting comorbid conditions, duloxetine was the first line pharmacotherapeutic strategy for chronic pain, escitalopram was the first-line pharmacotherapeutic strategy for diabetes, hypertension, liver disease, Parkinson’s disease, renal disease, epilepsy, and thyroid disease, and sertraline was a first-line pharmacotherapeutic strategy for arrhythmia and cardiovascular disease. Conclusion Pharmacological treatment strategy of KMAP-DD 2021 is similar to that of KMAPDD 2017. Additional study is required to determine antidepressant choices for TRD and cancer patients with depression.

상흉추강내에 발생한 신경장 낭종 - 증 례 보 고 -

송관영,김혁수,정명훈,안치성,최선욱,최일승,강동수,Song, Kwan Young,Kim, Hyug Soo,Jung, Myung Hoon,Ahn, Chi Sung,Choi, Sun Wook,Choe, Il Seung,Kang, Dong Soo 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.8

Spinal neurenteric cyst results from the persistence of an abnormal communication between endodermal and ne-uroectodermal layer. Embryologically, neurenteric cyst is derived from endoderm that is fused with the developing notochord during the third week of gestation. It is a rare malformation that lead to spinal cord compression. The patient is 19-year-old male presented with chest pain, paresthesia and progressive weakness in his low extremities(grade II/II). Preoperative MR imaging revealed intradural extramedullary cyst with intracystic hemorrhage in T1 and T2 level that is ventrally located and compressed the spinal cord. Involved vertebral bodies were scalloped and fused. The cystic tumor were totally removed through costotransversectomy approach. Postoperatively, motor weakness of the low extremities were improved to the level of grade IV/V. And chest pain and paresthesia were gradually disappeared. Postoperative MR imaging showed the decompression of the thoracic spinal cord. Histologic examination revealed a ciliated columnar epithelial neurenteric cyst. The pre- and postoperative clinical, radiological features of a case of upper thoracic neurenteric cyst is described with review of literature.

병적 도박 환자에서의 회백질 부피 변화 분석 : 화소 기반 형태분석 방법을 이용한 예비 연구

최정석,신영철,정위훈,정명훈,장준환,강도형,최치훈,권준수,이준영,Choi, Jung-Seok,Shin, Young-Chul,Jung, Wi Hoon,Jung, Myung Hun,Jang, Joon Hwan,Kang, Do-Hyung,Choi, Chi-Hoon,Kwon, Jun Soo,Lee, Jun-Young 대한생물정신의학회 2009 생물정신의학 Vol.16 No.3

Objectives : The purpose of this study was to examine structural abnormalities of brain in patients with pathological gambling(PG) using voxel-based morphometry. Methods : We compared gray matter(GM) volumes between 10 patients with PG and 14 age- and IQ-matched healthy controls and examined the relationship of GM volumes with clinical variables in patients with PG. Results : We found significant increase of GM volume in the superior, middle, and inferior frontal gyri, the midbrain, the middle temporal gyrus, the precuneus, and the fusiform gyrus of patients with PG. A significant decrease of GM volume was observed in the parahippocampal gyrus and the lingual gyrus of the patient group. In addition, GM volumes in some of these regions were positively associated with South Oaks Gambling Screen score and negatively with age of onset in patients with PG. Conclusion : Current findings indicate that structural abnormalities in the fronto-temporal cortex, the midbrain, and the precuneus might be involved in the pathophysiology of PG, and contribute to some of the behavioral changes observed in patients with PG.

아밀로스 함량에 따른 쌀쿠키의 품질특성

권유리(Yu-Ri Kwon),정명훈(Myung-Hoon Jung),조준현(Jun Hyeon Cho),송유천(You-Chun Song),강항원(Hang-Won Kang),이원영(Won-Young Lee),윤광섭(Kwang-Sup Youn) 한국식품영양과학회 2011 한국식품영양과학회지 Vol.40 No.6

아밀로스 함량이 다른 진수미와 밀양261호 쌀가루를 첨가하여 제조한 쌀쿠키의 품질특성을 조사하였다. 반죽의 밀도는 진수미를 첨가한 쿠키가 쌀가루 첨가에 따라 감소하였으나 밀양261호는 첨가량에 따른 유의적인 차이는 없었으며, 반죽의 pH는 쌀가루 첨가에 따라 대조구에 비하여 낮은 값을 나타내었다. 쿠키의 수분함량은 쌀가루 함량이 많아짐에 따라 증가하였으며 특히 진수미 첨가 쿠키의 수분함량이 높았으며, 퍼짐성에서는 진수미와 밀양261호 첨가 쿠키 모두 쌀가루를 50% 대체한 쿠키가 대조구보다 유의적으로 높은 퍼짐성을 보였다. 쌀쿠키의 경도는 아밀로스 함량이 높을수록 낮아졌으며, 노화도 측정결과 저장 4일째 밀양261호 첨가쿠키는 30% 이상 첨가 시 경도의 변화가 거의 없어 노화에 큰 영향이 없었다. 관능평가 결과 대조구가 다른 쌀가루 첨가구보다 좋은 결과를 보였으며 쌀가루 함량이 높아질수록 색과 풍미, 경도 등에서 낮은 점수를 보여 쌀가루보다 밀가루의 풍미와 식감을 선호하는 것을 나타내었다. 이와 같은 결과를 통하여 밀양261호가 쌀쿠키 제조에 있어서 좋은 가공적성을 보였으며, 특히 쌀가루가 30% 이상 첨가된 쿠키는 노화에 대한 안정성을 보였다. Physicochemical and sensory characteristics of rice cookies prepared with various levels of amylose content were investigated in this study. Dough pH of Jinsumi and Milyang 261 cookies was decreased by addition of rice flour. Density of dough with 100% substituted Jinsumi flour had the largest value of 1.09 g/㎖, whereas that of Milyang 261 cookies showed no significant difference. Spread ratio of cookies was the largest in the cookies containing Jinsumi, and Milyang 261 constituted the 50% group. Preservation ability of Milyang 261 cookies surpassed above 30%. Lightness of Jinsumi and Milyang 261 cookies increased with increasing rice flour content. The results of our sensory evaluation demonstrated that the control sample was significantly more preferable in terms of overall acceptability compared to others. These results suggest that adding 30% Milyang 261 flour is the best substitution ratio for rice cookies.

공황장애 환자의 초기부적응 심리도식의 특성

우나영,이병욱,이홍석,정명훈,이중서,Woo, Na Young,Lee, Byung Wook,Lee, Hong Seock,Jung, Myung Hoon,Yi, Jung Seo 대한불안의학회 2011 대한불안의학회지 Vol.7 No.2

본 연구에서는 공황장애 환자의 심리도식 특성을 조사하였다. 대조군에 비해 환자군은 상태 및 특성불안, 우울 점수가 유의하게 높았으며 YSQ 중에서는 유기/불안정, 위험/질병에 대한 취약성 도식 점수가 유의하게 높았다. 환자군에서 ST-AI로 평가한 불안 수준은 모든 심리도식과, BDI로 평가한 우울 수준은 특권의식/과대성을 제외한 14개 도식과 상관관계가 있었으나 대조군에서는 훨씬 적은 수의 도식만이 상관관계를 보였다. 환자군에서 위험/질병에 대한 취약성, 유기/불안정 도식이 특성불안 수준을 가장 잘 예측하였으며 의존/무능, 유기/불안정 도식은 상태불안 수준을, 결함/수치심, 복종 도식은 우울 수준을 가장 잘 예측하였다. 이를 종합할 때, 초기부적응 심리도식은 공황장애의 발병과 경과 그리고 치료 반응에 영향을 미칠 가능성이 있다. 향후 대규모 집단을 대상으로 공황장애 환자의 심리도식 특성을 파악하고 치료에 접목시키는 작업이 필요할 것으로 생각된다. Objective : This study aimed to investigate the characteristics of the early maladaptive schemas in patients with panic disorder. Methods : Patients (n=35) included people who had met the DSM-IV-TR criteria for panic disorder. The normal control group (n=35) were those people who had no psychiatric disorder and had never experienced panic attack. The early maladaptive schemas and the severity of depression and anxiety were assessed by the Young Schema Questionnaire Short-form (YSQ-SF), the Beck Depression Inventory (BDI), and the Spielberger State-Trait Anxiety Inventory (STAI). Results : The scores on the STAI-S, STAI-T, and BDI were significantly higher in the patient group. Compared to the control group, the scores of vulnerability to harm and illness, and abandonment/instability schemas were significantly higher in the patient group. In the patient group, defectiveness/shame and subjugation schemas were found to predict BDI, dependent/incompetence, abandonment/instability schemas were found to predict STAI-S, and vulnerability to harm and illness, and abandonment/instability schemas were found to predict STAI-T. In normal controls, failure and insufficient self-control/self-discipline, failure, and emotion inhibition schemas were found to predict BDI, STAI-T, and STAI-S. Conclusions : Vulnerability to harm and illness and abandonment/instability schemas may be characteristic schema in patients with panic disorder.

라즈베리파이 파이3를 이용한 동작 감지형 네트워크 블랙박스 구현

강승호(Seung-Ho Kang),김범중(Byum-Jung Kim),이재훈(Jae-Hoon Lee),정도령(Do-Ryung Jeong),정명훈(Myung-Hoon Jeong),김윤호(Yoon-Ho Kim) 한국정보기술학회 2017 Proceedings of KIIT Conference Vol.2017 No.6

Tetragonal Pyramid 모델을 이용한 Computer Assisted Proximal Tibia Osteotomy (CAPTO)

이호상(Ho-Sang Lee),김철웅(Cheol-Woong Kim),정명훈(Myung-Hoon Jung) 한국정밀공학회 2009 한국정밀공학회 학술발표대회 논문집 Vol.2009 No.6월

화상 환자에서 신속 순차 시각 제시를 이용한 주의깜빡임에 관한 예비연구

김대희,전보라,서정훈,조용석,임해준,허준,김도헌,전욱,김종현,정명훈,최인근,이병철,Kim, Dae Hee,Jun, Bora,Seo, Cheong Hoon,Cho, Yongsuk,Yim, Haejun,Hur, Jun,Kim, Dohern,Chun, Wook,Kim, Jonghyun,Jung, Myung Hun,Choi, Ihngeun,Lee, Boung Ch 대한생물정신의학회 2010 생물정신의학 Vol.17 No.2

Objectives : Trauma patients have attentional bias which enforces traumatic memories and causes cognitive errors. Understanding of such selective attention may explain many aspects of the posttraumatic stress disorder(PTSD) symptoms. Methods : We used the rapid serial visual presentation(RSVP) method to verify attentional blink in burn patients with PTSD. International affective picture system(IAPS) was used as stimuli and distracters. In the 'neutral test', patients have been presented series of pictures with human face picture as target stimuli. Each picture had 100ms interval. However the distance between target facial pictures was randomized and recognition of second facial picture accuracy was measured. In the 'stress test', the first target was stress picture which arouses patient emotions instead of the facial picture. Neutral and Stress tests were done with seven PTSD patients and 20 controls. In '85ms test' the interval was reduced to 85ms. The accuracy of recognition of second target facial picture was rated in all three tests. Eighty-five ms study was done with eighteen PTSD patients. Results : Attentional blinks were observed in 100-400ms of RSVP. PTSD patients showed increased recognition rate in the 'stress test' compared with the 'neutral test'. When presentation interval was decreased to 85 ms, PTSD patient showed decrease of attentional blink effect when target facial picture interval was 170ms. Conclusion : We found attentional blink effect could be affected by stress stimulus in burn patients. And attentional blink may be affected by stimulus interval and the character of stimulus. There may be some other specific mechanism related with selective attention in attentional blink especially with facial picture processing.

연구논문 : 건조방법에 따른 브라운소스의 품질 특성

이종필 ( Jong Phil Lee ),김동석 ( Dong Seok Kim ),최수근 ( Soo Keun Choi ),윤광섭 ( Kwnag Sup Youn ),정명훈 ( Myung Hoon Jung ) 한국식품조리과학회(구 한국조리과학회) 2011 한국식품조리과학회지 Vol.27 No.1

The aim of this study was to develop a convenient brown sauce product with long shelf life that has similar taste and quality characteristics with sauce used in restaurants. Response surface analysis was carried out to optimize brown sauce. Extracted brown sauce powder was subjected to hot air drying, infrared drying, freeze drying, and spray drying to determine the appropriate drying method for brown sauce manufacturing. The optimum extraction conditions were set by superimposing and reading each reaction surface that satisfied all of the sensory characteristics such as color, smell, taste, concentration, and overall preference level in order to set the optimum conditions for brown sauce production. The optimum extraction conditions for brown sauce were determined to be heating time 30 min, gelatin addition quantity 9.00%, and tomato paste addition quantity 11.25%. Reliability test showed a similar value to the predicted scope when compared to the experimental value obtained under the same conditions as the predicted value according to RSM (response surface methodology), enabling verification of the derived regression formula. Product powder of ideal brown sauce by heating, infrared radiation, freezing, and spray drying and investigate result for functional tests of color, flavor, taste, viscosity, overall acceptability and show highly acceptability on powder by infrared rays and freeze-drying methods. Especially, infrared radiation method resulted in favorable color and flavor values while freeze-drying method produced good taste and viscosity values and high overall acceptability. Therefore, infrared radiation drying method and freeze-drying method to product powder.