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        인플루엔자ㆍ조류인플루엔자의 역학 및 관리

        천병철(Byung-chul Chun),김재홍(Jae-hong Kim),이윤정(Yoon-jung Lee),강춘(Kang Chun),김현미(Hyun-mee Kim),권용국(Young-kuk Kwon),최준구(Jun-gu Choi),이은경(Eun-kyoung Lee),박최규(Choi-kyu Park),위성환(Sung-hwan Wee),최순자(Soon-ja Cho 한국역학회 2005 Epidemiology and Health Vol.27 No.1

        Natural infections with influenza A viruses have been reported in a variety of animal species including humans, pigs, horses, sea mammals, and birds. Although viruses of relatively few haemagglutinin(HA) and neuraminidase(NA) subtype combinations have been isolated from mammalian species, all subtypes, in most combinations, have been isolated from birds. During the past few years, several subtypes of avian influenza A have been shown to cross the species barrier and infect humans. During an outbreak of a highly pathogenic influenza A(H5N1) virus among poultry in Hong Kong in 1997, 6 of 18 people with confirmed infection died. And a total of 89 human infections with influenza A(H7N7), including 1 resulting in the death of a Dutch veterinarian, occurred during the extensive outbreak in 2003. During late 2003 and early 2004, there were reports of large outbreaks of H5Nl among poultry throughout Asia (including Korea, Japan, Indonesia, Vietnam, Thailand, Laos, Cambodia, and China). In Korea, we had also highly pathogenic avian influenza(HPAI) outbreak in 2003-2004 with a first suspected case reported on 10 December 2003. The case was reported at a parent stock farm for broilers, which was locatcd in Chungbuk province, and the farm was immediately placed under movement restrictions. Laboratory tests confirmed the outbreak of HPAI on 12 December 2003. Up to 20 March 2004, a total of 19 farms were confirmed as having been infected with HPAI virus. No further outbreaks occurred after that date. Fortunately there were no human cases founded in this epidemic in Korea. In January 2004, there was confirmation that influcnza A(H5N1) virus had bcen isolated from patients who had died of a respiratory illness in Vietnam. Total 107 human confirmed cases were reported until June 2005 to WHO, threatening new pandemic outbreak. We reviewed our prevention and control strategies of avian influenza and preparedness to the pandemic outbreak.

      • 한국 주택의 실내디자인 이미지 유형 및 특성 분석

        박영순,이윤정 연세대학교 생활과학연구소 1996 生活科學論集 Vol.10 No.-

        The purpose of this study was to classify the interior design images in Korea and to analyze the characteristics of the interior elements. To achieve the study purposes, review of literature, content analysis and questionnaire survey were used. Three hundreds sixty four interior photos were collected from 7 monthly magazines between 1990-1994 for a content analysis. Analyzed interior characteristics were composed of six main elements, such as architectural elements, textile elements, furniture, decoration, lighting and color. Major findings of the study is as follows: 1) Forty eight descriptors were found to describe Korean residential interior images. 2) Five major factors were identified to classify the interior image in Korean residential interior: traditional, comfortable, fresh, simple and noble image. 3) Furniture, textile and color elements were found to affect the interior design image more than architectural, decoration, lighting elements. The details of the interior elements affecting the interior image were flooring; window treatment; style, pattern and color of textile; style, linear characteristics, material and color of furniture; types of plant used in interior; hue of dominant color, chroma, value and hue of subdominant color, value of accent color.

      • 요실금이 있는 중년여성의 일상생활불편감 및 우울에 관한 연구

        김금순,이윤정,서문자,박영숙 서울대학교 간호대학 간호과학연구소 1999 간호학 논문집 Vol.13 No.1

        The purpose of this study was to explore the relating factors, discomfort and depression due to urinary incontinence in middle-aged women. The subjects were 215 women in the age 35-65 years old who dewelled in community. The data were collected from August to December in 1996 with interview using structured questionaire composing of items of general characteristics, obsteric characterisitcs, disease charactteristics, situation of experiencing urinary incontinence, discomfort, and terapeutic method, and Beck's depression inventory. The data were analysed using SPSS/PC+ program; Cronbach's, frequency, percentage, Spearman's or pearson's coefficient correlation. The results of this study were as follows: 1) The mean duration of experiencing the urinary incontinence was 36.16 moths and the 60.9% of the respondents experienced a few frequency of urinary incontinence and the 77.2% was somewhat small expressed as "wetting their clothes". 2) The urinary incontinence induced situations were coughing, sneezing, hasty, and ascending abdominal pressure. 3) The ost common situations of discomforts associated with hrinary incontinence were diversional activity such as exercise, long period journey, and interpersonal relations. 4) The 80.5% of ascending abdominal pressure experienced the urinary incontinence, and the most common symptom of urinary incontinence was the frequent urine(43.3%) 5) The urinary incontinence correlated with menopause, age of menopause(p<.05) and age group(p<.01) significantly. 6) The 89.7% of urinary incontinence were not treated, but they wanted to try noninvasive methods such as the herb medicine(27.4%), pelvic muscle exercise(27.0%), and biofeeback(4.2%). 7) situation of experiencing urinary incontinence, discomfort and symptoms of depression correlated with urinary incontinence significantly(p<.05). In conclusion, we need to develop and provide various nursing interventions such as the pelvic muscle exericse, biofeedback and stress & depresion management program in middle-aged women who dewells in community in view of quality of life, health maintenance and promotion.

      • SCOPUSKCI등재

        지속성 외래 복막투석 환자에서 혈중 Lopoprotein(a) 농도에 영향을 미치는 인자들에 대한 다변수 분석

        정영옥,박정식,이윤정,김유미,박종하,신영태,김순배,채동환 대한신장학회 1999 Kidney Research and Clinical Practice Vol.18 No.5

        Lp(a) is an independent risk factor of atherosclerotic cardiovascular diseases. Marked increase in plasma lipoprotein(a)[Lp(a)] was reported in continuous ambulatory peritoneal dialysis(CAPD) patients. Serum albumin, parameters of nutritional status and parameters of dialysis have been reported to be related with Lp(a) concentration. Eighty nine patients(age 52±13, M: F 61: 28) undergoing CAPD were included in this study. We measured Lp(a) concentration, apolipoprotein(a) [apo(a)] phenotype, serum albumin, parathyroid hormone (PTH), Creactive protein(CRP), fibrinogen, 24 hour peritosol protein ancl albumin, 24 hour urine protein and albumin, total albumin clearance, residual renal function(RRF), and parameters of nutritional status such as prealbumin, triceps skin fold(TSF), mid-arm muscle area(MAMA), and normalized protein catabolic rate(nPCR). Peritoneal equilibration test(PET) and weekly Kt/V,. were also measured to evaluate relationship of Lp(a) and the adequacy of dialysis. The median serum Lp(a) was 48.9mg/dl(29.1-73.5 mg/dl)(quartiles). Higher Lp(a) level was observed in the low molecular weight apo(a) subgroup. There was no significant difference in serum Lp(a) levels between male and female, diabetic and non-diabetic patients, smokers and non-smokers. Serum albumin was negatively correlated(r=-0.28, p$lt;0.01), while total albumin clearance was positively correlated with Lp (a)(r=0.20, p$lt;0.05). 4)gLp(a) was not correlated with age, duration of dialysis, prealbumin, fibrinogen, RRF, weekly Kt/V, PET, PTH, CRP, TSF, MAMA, nPCR, 24hour peritosol protein and albumin and 24hour urine protein and albumin. Multivariate analysis using apo(a) phenotype, serurn albumin, total albumin clearance as independent variables revealed that serum albumin and apo(a) phenotype were significantly related with logLp(a)(p$lt;0.05). Apo(a) phenotype and serum albumin were the factors that were independently associated with serum Lp(a) concentration in CAPD patients.

      • SCOPUSKCI등재

        항갑상선제 투여 중 발생한 간 손상

        이기영,이윤정,박혜영,강문호,김홍규,이성광,정연실,홍순홍,정성권,이화은,서찬종 대한내분비학회 2000 Endocrinology and metabolism Vol.15 No.4

        Background: Propylthiouracil (PIV) and methimazole (MMI) were widely used for the treatment of hyperthyroidism. Hepatic injury caused by these agents is a rare but serious complication. This study is to investigate the clinical features of hepatotoxicity from antithyroid drugs. Methods: We reviewed 17 cases of hepatic injury during treatment with antithyroid drugs in patients with hyperthyroidism. Included were 6 cases we experienced and 11 cases reported in Korean literature from 1986 to 1999. We analyzed the clinical features of hepatic injury. Results: Of 17 cases of hepatic injury, 12 were PTU cases and 5 MMI cases. The mean age of PTU cases was 40 years with 6/12 patients over 40 years old and 2/5 MMI cases were over 40 years old. The dose of PTU was 300 mg/d or more in 10/12 cases (83%) and the dose of MMI was 30 mg/d in 3/5 cases (60%). The hepatic injury occurred within 3 months in 8/12 PTU cases (67%) and within 2 months in 4/5 MMI cases (80%). The duration of hepatic injury tended to be longer in MMI cases than in PTV cases (median; 80 vs 41 days, p=0.102). In PTU cases, the duration of hepatic injury was correlated with the duration of drug use before hepatic injury (p$lt;0.05). All of 8 biopsied cases who took PTU had predominantly hepatocellular necrosis. Two biopsied cases who took MMI had cholestatic jaundice and nonspecific abnormality, respectively. Biochemical findings of all MMI cases were compatible with cholestatic jaundice. As to the treatment of hyperthyroidism after hepatic injury, 4/12 PTU cases were treated with RAI therapy, 5 with MMI and one with surgery, and treatment was unknown in two. On the other hand 3/5 MMI cases interestingly entered into spontaneous remission after hepatic injury and 2/5 had RAI therapy. Hepatic dysfunction recurred in each one whom treatment by changing to MMI or PTU was tried on. Conclusion: Most of hepatic injury during treatment with antithyroid drugs developed within two to three months of drug use. The hepatic injury related to PTU was mainly cytotoxic whereas that related to MMI was cholestatic. Since there is a cross-reaction between PTU and MMI in hepatotoxicity, RAI therapy or operation shoud be considered as an alternative treatment of hyperthyroidism after hepatic injury (J Kor Soc Endocrinol 15:554-560, 2000).

      • SCOPUSKCI등재
      • KCI등재

        전신마취 하의 복강경 질식 자궁적출술 수술시 가온요법 적용의 효과 비교

        서용원,이윤정,박양숙,신정숙,조연숙,배상희,박순이,유지영,이정은,한금선 병원간호사회 2006 임상간호연구 Vol.12 No.1

        Purpose: This study aimed to compare the effects of application of heating therapies using heated water circulation pads with those of heated irrigation fluid. Method: Patients were divided into a comparison group of 30 persons, a group of 30 persons to which heated water circulation pads were applied, and a group of 30 persons to which heated irrigation fluid was applied. The body temperature was measured every 15 minutes during operations in the esophagi at locations 1/3 above the lower ends thereof. Result: There was no significant difference in the decrease of body temperature during the operation, while there was a significant difference at the time of termination of anesthesia. There was no significant difference in the rate of occurrence of hypothermia. However, there was a significant difference in the time of arrival at the lowest body temperature. Conclusion: It is concluded that the application of heating therapies to LAVH patients under general anesthesia is desirable. The two heating therapies exhibit almost equivalent effects. Meanwhile, the heating therapy using heated irrigation fluid is advantageous in that the application thereof is easy and the cost of application is inexpensive.

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