서울시의 휘발성유기화합물의 정도관리 및 추이 분석

오혜린,김윤경,김용표 한국대기환경학회 2017 한국대기환경학회 학술대회논문집 Vol.2017 No.11

신생아에서 채혈 시 음악제공이 통증행동 반응에 미치는 효과

오혜린,양은주,이현주,박현경,김창렬 대한신생아학회 2013 Neonatal medicine Vol.20 No.4

Purpose: We studied this study to see the effect of hearing music on response to pain during needling. We hypothesized that music would reduce pain in newborns. Methods: Twenty term and near-term newborns were enrolled for the study. They were admitted to neonatal intensive care unit of Hanyang University Guri Hospital from May 1, 2011 to September 30, 2011. We evaluated pain response to needling, such as arterial puncture or heel prick, by using Neonatal Infant Pain Scale (NIPS; facial expression, crying, breathing patterns, arms, legs, state of arousal) and duration of crying through video recording. We started video recording when the newborns were stable with 0 score of NIPS, and continued for 3 minutes after needling. Each newborn took video-recordings in 2 separate periods. One was done with hearing music (Music group) and the other without music (Control group). Two observers reviewed the videotapes and gave final scores in agreement. T-test was done for comparisons of pain scale and duration of crying between music and control groups. Results: Mean age and hospital days at test of the subjects were 6±5 days of life (1-16 days of life) and 3±2 days, respectively. Twenty-one of 40 needlings (52.5%) for blood sample were from radial arterial puncture and 19 (47.5%) from heel prick. The music group had lower NIPS score than the controls (5.6±1.1 vs 6.5±0.7, P=0.006). Among the NIPS parameters, the music group had lower scores in crying and arm (crying, 1.6±0.5 vs 1.9±0.3, P=0.028; arm, 0.3±0.5 vs 0.7±0.5, P=0.01) parameters. The remaining parameters such as facial expression, leg, breathing patterns and state of arousal, and duration of crying were not significantly different in 2 groups. Conclusion: c reduced pain response to needling in newborns. Music could be one of modalities to relieve pain during routine medical procedures in newborns. 목적: 신생아에서 채혈 중 통증완화를 위한 비약물적 중재방법의 하나인 음악이 통증행동 반응에 미치는 영향을 알아보고자 연구를 시행하였다. 방법: 본 연구의 대상은 2011년 5월 1일부터 9월 30일까지 한양대학교 구리병원의 신생아실과 신생아중환자실에 입원한 신생아로 보호자의 동의를 얻은 신생아 20명을 대상으로 신생아 1명당 2회의 다른 채혈시기에 한 번은 음악을 제공하고(음악군), 다른 한 번은 음악제공 없이(대조군) 채혈한 후 3분간 신생아에 대한 비디오 녹화를 통하여두 군 간에 통증 정도를 비교 평가하였다. 신생아 통증 정도는 신생아 영아 통증척도(neonatal infant pain scale,NIPS)를 이용하였고, 울음지속시간도 함께 측정하였다. 신생아 통증 척도는 신생아실에서 5년 이상 근무한 간호사 두 명이 녹화된 비디오테이프를 보며 점수를 측정하였고, 음악군과 대조군의 통증점수 비교는 t-test를 사용하였다. 결과: 신생아들의 평균나이는 6±5일(1-16일)이었고 채혈 시 평균 재원일수는 3±2일이었으며 평균 재태기간은 38±2주(35-41주)였다. 40회의 채혈 중 요골동맥천자는 21회(52.5%), 발뒤꿈치 채혈은 19회(47.5%)였다. NIPS점수는음악군에서 대조군에 비해 낮았으며(5.6±1.1 vs 6.5±0.7, P<0.007) 이 중 울음과 팔 움직임에 의미 있는 차이를보였고(울음 1.6±0.5 vs 1.9±0.3, P<0.03; 팔 움직임 0.3±0.5 vs 0.7±0.5, P<0.02), 얼굴표정, 호흡양상, 다리움직임, 각성상태, 울음지속시간은 두 군간에 유의한 차이는 없었다. 결론: 신생아 채혈 중 음악이 신생아 통증척도를 감소시켰다. 따라서, 음악이 신생아의 통증 관리를 위한 효율적인 중재 방법의 하나가 될 수 있을 것이다.

어린이 위생교육용 입체 동화책 개발 및 교육 현장 활용도 평가

오혜린,이지원,최향숙 한국식품영양학회 2020 한국식품영양학회 학술대회논문집(학술심포지움) Vol.2020 No.10

들깨박을 첨가한 식물성 쌀쿠키의 항산화 활성 및 품질특성

오혜린,김명현,한영실 한국식품영양과학회 2022 한국식품영양과학회지 Vol.51 No.9

본 연구에서는 부산물인 들깨박을 기능성 소재로의 활용 가능성을 알아보고 들깨박 분말을 이용한 기능성 식품으로 쌀쿠키 개발을 위해 들깨박 분말을 각각 0%, 5%, 10%, 15%, 20%를 첨가한 쌀쿠키를 제조하여 쌀쿠키의 항산화 활성과 품질특성을 실험하였다. 들깨박 분말의 총 폴리페놀과 플라보노이드는 111.00 mg GAE/g과 47.06 mg QE/g이었으며, 이를 쌀쿠키에 첨가한 경우 시료 첨가량과 비례하여 총 폴리페놀 함량과 총 플라보노이드 함량이 증가하였다. 들깨박 분말의 DPPH 및 ABTS 라디칼 소거 활성을 측정한 결과 각각 IC50값은 28.15 µg/mL, 193.04 µg/mL로 나타났다. 제조된 쌀쿠키의 DPPH 및 ABTS 라디칼 소거 활성은 들깨박 분말 첨가량 증가에 따라 유의적으로 항산화 활성을 보였다. 들깨박 분말을 첨가한 쌀쿠키의 품질 평가로는 밀도, pH, 퍼짐성, 손실률, 팽창률, 색도, 수분함량, 경도 평가를 실시하였다. 쌀쿠키의 밀도는 유의적인 결과를 보이지 않았고, pH는 들깨박 첨가량이 증가함에 따라 감소하였다. 들깨박 첨가량에 비례하여 퍼짐성은 높아졌고, 손실률과 팽창률은 첨가량이 증가함에 따라 낮아졌다. 색도의 L값은 들깨박 첨가량에 따라 낮아졌고, a값과 b값은 높아지는 결과를 보였다. 수분함량과 경도는 시료 첨가량과 반비례하여 감소하였다. 쌀쿠키의 특성 강도 검사에서는 들깨박 분말의 첨가량이 증가할수록 들깨박 향, 먹은 뒤의 목 넘김, 고소한 맛, 어두움이 강해졌으며 단단함은 줄어들었다고 평가되었다. 기호도 검사에서는 대조군보다 첨가군이 높은 평가 점수를 받았으며 들깨박 분말 15% 첨가군이 전반적으로 가장 높은 기호도를 보였다. 이런 결과를 종합한다면 쌀쿠키에 들깨박 분말을 첨가하는 것은 항산화능을 증가시켜 쌀쿠키의 가치를 높일 수 있고 건강 지향적인 부분을 고려한 쌀쿠키 개발이 가능할 것으로 판단된다. 또한 코코넛 오일로 동물성 유지를 대체한 식물성 쿠키로 건강 기능성 식품으로의 가치가 높을 것으로 판단되며, 특히 들깨박 분말 15% 첨가가 생리활성 측면과 전반적인 기호도를 고려할 때 가장 적절하게 쌀쿠키의 가치를 높일 수 있을 것으로 예상된다. 들깨박 분말을 첨가한 식품 모델 연구는 아직 부족하므로 본 연구는 향후 식품 가공 부산물이자 기능성 소재인 들깨박을 활용한 다양한 식품개발에 기여할 것으로 판단된다.

Severe Cutaneous Adverse Reactions in Korean Pediatric Patients: A Study From the Korea SCAR Registry

오혜린,강동윤,강혜련,김수정,고영일,김세훈,김민혜,서동인 대한천식알레르기학회 2019 Allergy, Asthma & Immunology Research Vol.11 No.2

Purpose: Although severe cutaneous adverse drug reactions (SCARs) are rare, they are associated with high morbidity and mortality, and thus early diagnosis and treatment are critical for improving prognoses. However, few studies have reported the characteristics of SCARs in children. Thus, we aimed to evaluate the clinical characteristics, current management and prognosis of pediatric SCARs. Methods: We analyzed pediatric data in the Korean SCARs registry, which was built retrospectively in 2016 with SCAR cases treated in 34 tertiary referral university hospitals during 2010–2015. Using these cases, we descriptively analyzed detailed data regarding etiology, clinical and laboratory features, treatment strategies, and prognosis. Results: Forty-seven pediatric SCAR cases from 15 tertiary referral hospitals were included. The median patient age was 10 (interquartile range, 3-15.5) years and 68.1% (n = 32) were males. The culprit drug was identified in 95.7% (n = 45) of the patients; antibiotics (44.7%) and antiepileptic drugs (19.1%) were the most common and second most common culprits, respectively. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) cases presented with the largest area of skin involvement without permanent sequelae. Stevens-Johnson syndrome (SJS) cases involved relatively small areas of skin but serious sequelae in two children. Of 4 patients with toxic epidermal necrolysis (TEN), 1 died. Of all patients assessed, 36 (76.6%) received systemic steroids and 21 (44.7%) received intravenous immunoglobulin (IVIG). Thirteen (27.7%) received both systemic steroids and IVIG. Cyclosporine was administered to only 1 patient along with a systemic steroid. Conclusions: In patients with pediatric SCARs, including those with DRESS, SJS and TEN, clinical presentations were variable. Thus, there was no clear continuous disease spectrum. Although the mortality rate was low (2.1%), clinical suspicion may be the best tool for proactive SCAR management.

패션 플래그쉽 스토어에 나타난 퍼놀로지(Funology) 공간 특성연구

오혜린(Oh, Hye-Lin),김개천(Kim, Kai-Chun) 한국실내디자인학회 2017 한국실내디자인학회논문집 Vol.26 No.6

In the 21st century, modern society is rapidly changing paradigm of environment with advancement of advanced technology and improving income levels. Such a paradigm reflected in modern design and emerged as a new spatial aspect through various cultural and artistic expressions, thus becoming a crucial role in commercial space. Reflecting on this phenomenon, fashion brands have expanded the concept of a variety of cultural, artistic, and experience cultures with a variety of cultural and artistic sectors in each of the world"s major cities. The fashion companies began to focus on fashion programs featuring "Funology" as the fun which creates a sense of curiosity rather than a meaningless space and a fun experience. Therefore, this study analyzes the spatial characteristics of fashion flagship store sites using characteristics of fashion flagship store presented in the expressions of fashion, and analyzes the spatial characteristics of the fashion flagship store based on the spatial characteristics derived from the spatial characteristics of the fashion scene. Based on these results, we confirm the relationship between the Fashion Flagship and the Funology. Design Aspects of the Fashion Flagship Store with Elements of Fun and We expect continuous research as a strategic factor that provides limitless ideas for many design and creative activities.

대기 에어로졸 포집시 필터 산처리 유무에 따른 리튬 농도 및 리튬 동위원소 비교실험

오혜린(HyeRin Oh),최혜빈(Hye-Bin Choi),김송이(Songyi Kim),류종식(Jong-Sik Ryu),이정훈(Jeonghoon Lee) 대한지질학회 2017 대한지질학회 학술대회 Vol.2017 No.10

Test for Respiratory and Asthma Control in Kids 설문지의 한국어 번역 및 번역본의 언어 타당도

오혜린 ( Hea Lin Oh ),고영률 ( Young Yull Koh ),서동인 ( Dong In Suh ),강병철 ( Byoung Chul Kang ),김봉성 ( Bong Seong Kim ),김우경 ( Woo Kyung Kim ),김자경 ( Ja Kyoung Kim ),김진택 ( Jin Tack Kim ),김효빈 ( Hyo Bin Kim ),박근화 ( 대한천식알레르기학회 2016 Allergy Asthma & Respiratory Disease Vol.4 No.1

Purpose: We aimed to translate the Test for Respiratory and Asthma Control in Kids (TRACK) instrument into Korean, with subsequent linguistic validation. Methods: The multistep process of forward translation, reconciliation, back-translation, cognitive debriefing, and proofreading of the Korean version of the TRACK was completed. Results: Two bilingual medical personnel independently translated the original English version of the TRACK into Korean one. After moderating the translation into a single reconciled one, 4 other bilingual persons were invited to translate the Korean draft back into an English one. Discrepancies between the original English version and the back-translated one were reviewed, and the need to modify the reconciled Korean draft was discussed. Twenty caregivers of asthmatic children took part in interviews that examine the appropriateness of the Korean version of the TRACK. The feedback from caregivers were then reviewed by a panel of pediatric allergists and reflected in the final Korean version. The document was finally proofread to check the spelling, grammar, layout and formatting. Conclusion: Translation and linguistic validation of the Korean version of the TRACK instrument were completed.

메가요트 실내 공간의 배치유형 및 동선체계 분석 연구

오혜린(Oh, Hye-Lin),손서연(Son, Seo-Yeon),박정남(Park, Jung-Nam),안성모(Ahn, Seong-Mo),김개천(Kim, Kai-Chun) 한국실내디자인학회 2017 한국실내디자인학회 학술대회논문집 Vol.2017 No.5

Along with the enhanced interest on the convergence of shipping and IT technology, recuperation and leisure due to the 4th Industrial Revolution, high added-value maritime leisure industry has a considerable growth potential. Accordingly, this research analyzed the space formation factors, placing type, interior space division and traffic line of 3DECK, the most representative mega yacht. The summarized results are as follows. First, mega yachts with the whole length shorter than 36.5m are consisted of 3 decks (sun deck, main deck and low deck) and their space formation is categorized into A~E types according to placing. Secondly, characteristics of A~E types showcased fly bridge for sun deck, stern deck, salon, dining room, wheel house, bow deck for main deck, master room, guest room, VIP room, staff room, tender boat and engine room for low deck for A, C types. For B, D, E types, staff room was mainly located in the bow area and the wheel house in the sun deck. Thirdly, they are flat-divided into the staff area and passenger & ship owner area with a partition wall and elevation-divided by a deck. Typically, main traffic line of passengers and ship owners are shown on the starboard and the traffic line of the staff on the portside.

양팔의 저림과 틱 유사증세로 내원한 소아 경추 추간판 탈출증 1례

오혜린(Hea Lin O),문진화(Jin Hwa Moon),염명걸(Myung-Kul Yum),설인준(In Joon Seol),박동우(Dong Woo Park) 대한소아신경학회 2012 대한소아신경학회지 Vol.20 No.1

신체 활동량이 많은 소아에서 경추부 손상은 눈에 띄는 외상이 없고, 증상이 뚜렷하지 않은 경우 진단이 어려울 수 있다. 저자들은 양측 팔저림과 경부 틱유사증상을 주소로 내원한 8세 여아의 경추부 자기공명촬영검사에서 경추 추간판 탈출증을 발견하였고, 추간판 탈출증의 증상으로 틱 유사증상이 나타날 수 있는 것을 경험하였기에 이를 보고하는 바이다. Intervertebral disc herniation is rare in children and is reportedly related with disc calcification and traumatic injury. We report an 8 years old girl, who complained of tingling sensation in both arms and intentional tic like neck stretching for about 1 month. She had got unnoticed whiplash Injury 2 weeks before symptoms. She also had been taking lessons for taekwondo for one and half year. Physical examination was unremarkable. Her symptoms got aggravated over the next 4 weeks. Plain vertebral x-ray showed no abnormalities, but cervical spinal MRI revealed disc central herniations at C 5-6 and C 6-7 levels. We concluded that her paresthesia and tic like motion were related with cervical disc herniation from hyperflexion neck injury.