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배혜정 ( Hye Jeong Bae ),남미란 ( Mi Ran Nam ),이상만 ( Sang Man Lee ),정유진 ( Yu Jin Jung ),손병현 ( Byung Hyun Shon ),피영규 ( Young Gyu Phee ),정종현 ( Jong Hyeon Jung ) 한국환경과학회 2015 한국환경과학회지 Vol.24 No.5
This study was performed to identify the state of the exposure and characteristics of pollutants by each process at 4 casting sites located in Gyeongsang-do from April to November 2013. The concentrations of methanol, crystallized silica glass, formaldehyde and phenol were analyzed by different process - casting process, molding process, core process, and shakeout & finishing process. The highest concentration of methanol was found in casting and molding process, whereas the highest concentration of crystalline quartz(Silica) was observed in core process. The most oxidized steel dusts and the highest concentration of fume were found in shakeout & finishing process. As a result of this study, those labors working at the casting site were found to be constantly exposed to various forms of hazardous chemicals; therefore, it is considered that this is the time to manage and plan how to reduce them. In addition, it is required to thoroughly manage the local exhauster, and improve the process and working environment to reduce various forms of hazardous chemicals.
배혜정 ( Hye Jeong Bae ),정종현 ( Jong Hyeon Jung ),피영규 ( Young Gyu Phee ) 한국산업위생학회 2013 한국산업보건학회지 Vol.23 No.2
Objectives: This study was conducted to estimate quartz concentrations in the airborne respirable dust from concrete manufacturing industries and to compare performance of two analytical methods, direct on filter(DOF) and the transfer methods in the Fourier Transform Infrared Spectroscopy(FTIR). Methods: Total 36 area samples were collected from 8 concrete manufacturing industries. Each respirable dust sample was collected by a 25 mm cassette attached to a 10 mm Dorr-Oliver nylon cyclone. The quartz content was estimated using the intensity of the absorption peak of quartz at 799 cm -1 by FTIR. Results: By the comparison of quartz content in respirable dust between the two methods, the results of using DOF method were higher than that of transfer method. And the result of quartz concentrations in respirable dust estimated by DOF method were mostly higher than those by transfer method. Statistically significant difference of quartz concentrations in respirable dust were not found in shakeout, input, loading and transporting processes by two methods. But quartz concentrations in the molding process had the statistically significant difference between DOF and transfer method. Conclusions: The results of the study is suggested that, it be needed to correct the influence of the interferences in order to establish the DOF method when interfering minerals have an effect on quantitative analysis of quartz in respirable dust by the direct on filter method with FTIR.
정경선,배혜정,남미란,정종현,피영규,Jeong, Gyeong Seon,Bae, Hye Jeong,Nam, Mi Ran,Jung, Jong-Hyoen,Phee, Young Gyu 한국산업보건학회 2017 한국산업보건학회지 Vol.27 No.3
Objectives: This study was conducted toestimate quartz concentrations and contents in the airborne respirable dust from various industries. Methods: A total of 818 samples were collected from 174 industries. Respirable dust samples were collected using a cyclone equipped with a 37 mm, $5{\mu}m$ pore size PVC filter. The quartz concentrations were identified using the intensity of the absorption peak of quartz at $799cm^{-1}$ by Fourie Transformed Infrared Spectroscopy(FTIR). Results: The respective geometric means for quartz concentrations in the respirable dust were 0.0050, 0.0049, 0.0025, and $0.0019mg/m^3$ in foundries, ceramics, construction, and cement/stone. The geometric mean of quartz contents analyzed by FTIR were respectively 3.43, 1.99, 1.04, and 0.82% for ceramics, foundries, cement/stone, and construction. The rate of exceeding the Korean Occupational Exposure Limit($0.05mg/m^3$) was 2.03%, but rate of exceeding the American Conference of Governmental Industrial Hygienist(ACGIH) Threshold Limit Value($0.025mg/m^3$) was 7.12%. Conclusions: Given that foundries had a higher quartz concentration, there is a need to reduce respirable dust, such as through wet operation. In order to protect the health of workers exposed to mineral dust, it is necessary to actively consider strengthening the Korean Occupational Exposure Limit.
국내 입원한 성인 암환자의 정맥영양 사용에 대한 후향적 연구
박효정 ( Hyo Jung Park ),손유민 ( You Min Sohn ),정지은 ( Jee Eun Chung ),김정태 ( Jung Tae Kim ),양진아 ( Jin A Yang ),배혜정 ( Hye Jung Bae ),성예원 ( Ye Won Sung ),김선화 ( Sun Hwa Kim ),조지윤 ( Ji Yoon Cho ),정경미 ( Kyung Mi 한국정맥경장영양학회 2020 한국정맥경장영양학회지 Vol.12 No.2
Purpose: There have been no clinical studies on the characteristics of parenteral nutrition (PN) for adult cancer inpatients in South Korea. The published evidence describing modern PN practices in these patients is also extremely limited. Therefore in this retrospective multicenter cross-sectional study, we aimed to investigate the PN support practice in hospitalized adult cancer patients. Methods: The study included adult cancer patients hospitalized in nine hospitals in South Korea and received PN, during the period from August 1st, 2017 to October 30th, 2017. We evaluated the relevant hospital-based PN practices in this group. Results: Among the 11,580 inpatient admissions during this period, 759 cancer patients received PN (6.6%). The majority of enrolled patients (97.2%) used commercially available PN and 71.2% of these used peripheral PN formulations. The average in-hospital PN duration was 16.1±19.9 days. Patients received only 65.4±25.4% calories of the recommended target calories. The in-hospital mortality of enrolled patients was 26.1%. Conclusion: We conclude that commercial PN is the most common form of PN administered to hospitalized adult cancer patients and the overall in-hospital mortality in the patients using PN is higher in South Korea compared to other countries.
대구 안심연료단지 환경오염물질 노출 평가(3) -원소 탄소, 결정형 실리카 및 안정동위원소비를 이용한 오염원 기여율 및 분포특성-
정종현 ( Jong Hyeon Jung ),피영규 ( Young Gyu Phee ),손병현 ( Byung Hyun Shon ),배혜정 ( Hye Jeong Bae ),양원호 ( Won Ho Yang ),김지영 ( Ji Young Kim ),김근배 ( Geun Bae Kim ),최종우 ( Jong Woo Choi ),박성준 ( Sung Jun Park ),이 한국산업보건학회 2015 한국산업보건학회지 Vol.25 No.3
Objectives: This study measured and analyzed the concentrations of crystalline silica, elemental carbon and the contribution ratio of pollutants which influence environmental and respiratory disease around the Ansim Briquette Fuel Complex in Daegu, Korea. Methods: We analyzed the crystalline silica and elemental carbon in the air according to FTIR(Fourier Transform Infrared Spectroscopy) and NIOSH(National Institute of Occupation Safety and Health) method 5040, respectively. In addition, lead stable isotopes, and carbon and nitrogen stable isotopes were analyzed using MC-ICP/MS(Multi Collector-Inductively Coupled Plasma/Mass Spectrometer), and IRMS(Isotope Ratio Mass Spectrometer), respectively. Results: The concentration of crystalline silica in the direct exposure area around the Ansim Briquette Fuel Complex was found to be 0.0014±0.0005 ㎎/S㎥, but not to exceed the exposure standards of the ACGIH(American Conference of Governmental Industrial Hygienists). In the case of the autumn, the direct exposure area was found to show a level 2.5 times higher than the reference area, and on the whole, the direct exposure area was found to have a level 1.4 times higher than the reference area. The concentration of elemental carbon in the direct exposure area and in the reference area were found to be 0.0014±0.0006 ㎎/S㎥, and 0.0006±0.0003 ㎎/S㎥, respectively. This study confirmed the contribution ratio of coal raw materials to residentially deposited dusts in the area within 500 meters from the Ansim Briquette Fuel Complex and the surrounding area with a stable isotope ratio of 24.0%(0.7-62.7%) on average in the case of carbon and nitrogen, and 33.9%(26.6-54.1%) on average in the case of lead stable isotopes. Conclusions: This study was able to confirm correlations with coal raw materials used by the Ansim Briquette Fuel Complex and the surrounding area. The concentration of some pollutants, crystalline silica, and elemental carbon emitted to the direct-influence area around the Ansim Briquette Fuel Complex were relatively higher than in the reference area. Therefore, we need to impose continuous and substantive reduction countermeasures in the future to prevent particulate matter and coal raw materials in the study area. It is time for the local government and authorities to prepare active administrative methods such as the relocation of Ansim Briquette Fuel Complex.
극소 저출생 체중아에서 SMOFlipid의 투여가 미숙아 질환 예방에 미치는 영향: Cholestasis 예방 중심으로
김문진 ( Moon Jin Kim ),배혜정 ( Hye Jung Bae ),조윤숙 ( Yoon Sook Cho ),김귀숙 ( Kwi Suk Kim ),김향숙 ( Hyang Suk Kim ),이혜숙 ( Hye Suk Lee ),이주영 ( Ju Young Lee ),김이경 ( Ee Kyung Kim ),김한석 ( Han Suk Kim ) 한국정맥경장영양학회 2013 한국정맥경장영양학회지 Vol.5 No.2
Purpose: Very low birth weight infants (VLBWI) are found to have a higher incidence of cholestasis due to long-term total parenteral nutrition (TPN). Although there have been some studies on relationships between omega-3 fatty acids and reduced incidence of cholestasis, the advantages that the fatty acids provide for premature infant diseases have not yet been fully understood. The aim of this study was to evaluate the advantages of SMOFlipid, a lipid emulsion product that contains omega-3 over other lipid emulsion products that do not. Methods: The medical records of 182 newborn (127 boys and 55 girls) were reviewed retrospectively between April 2010 and August 2012. These infants were born with a birth weight of <1,500 g and administered either of lipid emulsions (Intra MCT 20% or SMOFlipid) from birth to a full-feeding condition at our neonatal intensive care unit. Cholestasis is defined as serum direct bilirubin (DB) >1.0 mg/dL when total bilirubin (TB) is <5 mg/dL or DB/TB ratio is >20% when TB >5 mg/dL. Results: The incidence of cholestasis was found to be lower in the SMOFlipid group than in the medium-chain triglyceride/long chain triglyceride (MCT/LCT) group (7.3% [4/55] versus 18.9% [24/127], P=0.046). At the start of lipid emulsion administration (day 0), the baseline bilirubin level showed no significant difference between the two groups. However, the maximum value of DB on days 7∼ 14 was lower in the SMOFlipid group than in the MCT/ LCT group (0.8 [0.3∼2.2] versus 1.1 [0.3∼2.8] mg/dL, P= 0.030). The DB/TB ratio was also lower in the SMOFlipid group than in the MCT/LCT group (10.2% [4.9%∼40.0%] versus 24.1% [5.1%∼62.5%], P=0.002). Conclusion: This study concluded that SMOFlipid was effective in the prevention of cholestasis in VLBWI. Therefore, omega-3-containing lipid emulsion can be highly recommended in premature babies, especially in VLBWI who require TPN support. (JKSPEN 2013;5(2):67-75)
성은창 ( Eun Chang Sung ),배혜정 ( Hye Jeong Bae ),정종현 ( Jong Hyoen Jung ),피영규 ( Young Gyu Phee ) 한국산업보건학회 (구 한국산업위생학회) 2015 한국산업보건학회지 Vol.25 No.4
Objectives: The purpose of this study was to evaluate quartz concentrations in airborne total and respirable dusts. Materials: Respirable dust samples were collected using a 10 mm aluminum cyclone equipped with a 37 mm5 ㎛ pore size PVC filter. Total dust samples were collected with a three stage cassette from three work sections at earthwork sites located in the South Chungcheong-do Province area. Results: The geometric means of quartz concentrations were 0.008 ㎎/㎥ and 0.004 ㎎/㎥ in total dust and respirable dust, respectively. The geometric means of quartz contents analyzed by FTIR were 3.74% in total dust and 3.16% in respirable dust. The geometric mean of quartz concentrations and contents in secondary blasting operations were higher than those in other operations. Conclusions: Given that secondary blasting operations had higher quartz concentrations, there is a need to reduce respirable dust, such as through wet operations.
석재가공 공정에서 발생되는 분진과 석영의 입자크기별 농도 특성
김성환 ( Seong Hwan Kim ),배혜정 ( Hye Jeong Bae ),정종현 ( Jong Hyon Jung ),피영규 ( Young Gyu Phee ) 한국산업보건학회 2014 한국산업보건학회지 Vol.24 No.4
Objectives: The purpose of this study was to evaluate quartz concentrations in airborne respirable dust and particle size-related quartz concentrations. Methods: Respirable dust samples were collected using a 10 mm Dorr-Oliver nylon cyclone equipped with a 37 mm, 5 ㎛ pore size PVC filter. Dust samples were collected with a Marple’s personal cascade impactor from stone grinding operations in five stone-related business located in the Gyeongsangbuk-do area. Results: The geometric mean of quartz concentration in the respirable dust was 0.170 ㎎/㎥, and the rate of exceeding the Korean Occupational Exposure Limit(KOEL) was 93.3%. The quartz concentration by particle size shows that it was the highest(0.115 ㎎ /㎥) in stage 5(3.50-6.00 ㎛), which corresponds with the size of respirable particle. The smaller the particle sizes were, the higher quartz the content became. The mass fractions of inhalable, thoracic, and respirable dust were 72.1%, 36.0%, and 14.4%. Conclusions: The rate of the quartz concentration in respirable dust from stone grinding operations exceeding the American Conference of Governmental Industrial Hygienists Threshold Limit Values was 100%, which means proper work environmental management is required through regular working environmental measurements. Given that the stone grinding operations had a higher small size dust concentrations, there is a need to reduce respirable dust, such as through wet operation and local exhaust ventilation.
동종 조혈모세포이식을 받은 환자군에서의 Fish Oil을 함유하는 정맥지방유제 공급의 효과
최지형 ( Ji Hyeong Choe ),이영주 ( Young Joo Lee ),배혜정 ( Hye Jung Bae ),정선회 ( Sun Hoi Jung ),한현주 ( Hyeon Joo Hahn ),고영일 ( Yungil Koh ) 한국정맥경장영양학회 2016 한국정맥경장영양학회지 Vol.8 No.1
Purpose: Omega-3 fatty acid is known for immunonutrition in that it has anti-inflammatory properties and improves the patients’immune function. The objective of this study was to determine the effects of a fish oil-based lipid emulsion for adult patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT).Methods: This was a retrospective study of 90 adult allogeneic HSCT patients from July 2011 to June 2015. The patients were divided into two groups according to the lipid type provided; fish oil group (FO group, n=55) and non-fish oil group (NFO group, n=35). The demographics, parenteral nutrition and lipid emulsion duration, length of hospital stay (LOS), weight change, 30 day mortality, survival period, incidence of acute graft-versus-host disease (aGVHD), neutropenic fever, sepsis, and re-hospitalization were collected from the electronic medical records.Results: The patients’ characteristics including age, sex, body mass index, and underlying disease were similar in the two groups. The incidence of aGVHD and infectious complications, mortality, LOS, re-hospitalization were also similar. The FO group showed weight gains, whereas the NFO group showed weight loss (FO vs. NFO=0.34% vs.-1.08%, P=0.245).Conclusion: The clinical outcomes were similar in the two groups but there was a tendency for gain weight in the FO group. A large, well designed study, and a dosing study will also be needed to determine the optimal dose range for HSCT patients.