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- 저자 : 손유민 ( You Min Sohn ) (검색결과 2 건)
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국내 입원한 성인 암환자의 정맥영양 사용에 대한 후향적 연구
박효정 ( Hyo Jung Park ),손유민 ( You Min Sohn ),정지은 ( Jee Eun Chung ),김정태 ( Jung Tae Kim ),양진아 ( Jin A Yang ),배혜정 ( Hye Jung Bae ),성예원 ( Ye Won Sung ),김선화 ( Sun Hwa Kim ),조지윤 ( Ji Yoon Cho ),정경미 ( Kyung Mi 한국정맥경장영양학회 2020 한국정맥경장영양학회지 Vol.12 No.2
Purpose: There have been no clinical studies on the characteristics of parenteral nutrition (PN) for adult cancer inpatients in South Korea. The published evidence describing modern PN practices in these patients is also extremely limited. Therefore in this retrospective multicenter cross-sectional study, we aimed to investigate the PN support practice in hospitalized adult cancer patients. Methods: The study included adult cancer patients hospitalized in nine hospitals in South Korea and received PN, during the period from August 1st, 2017 to October 30th, 2017. We evaluated the relevant hospital-based PN practices in this group. Results: Among the 11,580 inpatient admissions during this period, 759 cancer patients received PN (6.6%). The majority of enrolled patients (97.2%) used commercially available PN and 71.2% of these used peripheral PN formulations. The average in-hospital PN duration was 16.1±19.9 days. Patients received only 65.4±25.4% calories of the recommended target calories. The in-hospital mortality of enrolled patients was 26.1%. Conclusion: We conclude that commercial PN is the most common form of PN administered to hospitalized adult cancer patients and the overall in-hospital mortality in the patients using PN is higher in South Korea compared to other countries.
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고혈당증 환자의 내당능에 미치는 Lipid - Based TPN의 유효성에 관한 후향적, 대조군 비교시험
손유민,손기호 韓國病院藥師會 2005 병원약사회지 Vol.22 No.1
Hyperglycemia is one of the most important adverse effect in patients with diabetes, chemical diabetes or persistent hypermetabolic state who receiving dextrose-based TPN (D-TPN). A retrospective study was conducted to evaluate the effects of lipid-based TPN (L-TPN) versus D-TPN on the blood glucose level in adult hyperglycemic patients in Samsung Medical Center. As a study group, 31 patients were randomly selected among 53 hospitalized hyperglycemic patients from October, 2003 to August, 2004 who received L-TPN. As a control group, 88 patients were also randomly selected among 107 patients from March, 2001 to September, 2003 who received D-TPN. By reviewing medical records, the blood glucose levels before and after TPN administration were compared in both groups to evaluate the effects of L-TPN and D-TPN. Administrated insulin doses were checked in unit per day. Serum albumin levels were also checked as a nutritional assessment. Wilcoxon rank sum test was used to determine the differences. In the study group, the mean ± SD blood glucose level (mg/dl) after TPN administration was significantly lower than before administration (167.90 ± 46.79 vs. 233.95 ± 48.08, p = 0.001). The mean ± SD blood glucose levels in the control group were 262.24 ± 54.85 and 247.83 ± 89.23, before and after administration, respectively (p >0.05). The mean ± SD of before and after insulin administration doses (unit/day) in the study group were 20.10 ± 25.29 and 10.50 ± 17.71. The mean ± SD of before and after insulin administration in the control group were 17.09 ± 23.60 and 30.19 ± 24.27. Both groups showed similar nutritional improvement. Since the serum albumin levels were elevated. While there were no significant differences in blood glucose levels between before and after administration of D-TPN, even though insulin administration doses were significantly high after D-TPN, L-TPN had significant differences in blood glucose levels that came down to normal levels. Therefore, L-TPN was more effective in managing blood glucose level in hyperglycemic patients.
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