축압식 고압 연료분사펌프 시스템 특성 해석

박석범,구자예,Park, Seok Beom,Koo, Ja Ye 대한기계학회 1998 大韓機械學會論文集B Vol.22 No.8

Computational investigation was conducted to examine the performance of a high pressure common-rail fuel injection system which is used to power a passenger car direct injection (Dl) diesel engine. The pipe flows were modeled by one dimensional wave equation and solved by implicit FDM Each volume of injector was considered as chambers with orifice nozzle in connections. These simulation results were compared with the experimental data of Ganser Hydromag. The comparison of needle life and rate of injection between simulation data and experimental data showed quite a good agreement Different shape of injection rate can be made by adjusting the size of inlet orifice and exit orifice in the piston chamber The pilot injection was accomplished by adjusting command signal.

한국 청년층에서 reflectance spectrophotometer에 의한 UVB 조사 광량에 따른 홍반지수 및 색소지수

박석범,김병국,은희철,윤재일 ( Seok Beom Park,Byoung Kook Kim,Hee Chul Eun,Jai Il Youn ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.4

Background: Methods of estimating the erythema and pigmentation reactions, such as MPE (Minimal Perceptible Erythema), MED(Minimal Erythema Dose) and MMD(Minimal Melanogenic Dose), are vulnerable to the variations of subjective visual measurements. Objective : By using objective and quantitative methods, the erythema and pigmentaton responses were investigated. Methods : A sunlight, fluorescent lamp(Waldmann UV 800) was used as a UVB light source. Multiple sites of the lower back were irradiated with an increasing dose by a constant amount, With a reflectance spectrophotometer (DermaSpectrometer), erythema and melanin indices at control, MPE, MED, MMD sites were assessed. The dose-response angle of erythema and pigmentation were calculated. Results : The erythema and pigmetation indices at the control, MPE, MED and MMD sites were 8.7+2.0AU/30.5+2.6AU, 10.5+2.7AU/32.6+3.6AU, 13.2+3.5AU/32.6+3.3AU, and 10.4+3.0AU/ 33.5+2.7AU, respectively. The calculated dose-response angle accurately measured the response of skin to UVB irradiation. Conclusion . In this study, use of a reflectance spectrophotometer appeared to be a more sensitive and effective method than visual assessment, in addition, dose-response angles may be an objective index for determination of skin responses to UVB irradiation. (Kor J Dermatol 1997;35(4): 729-735)

그루브(Groove)에 대한 인지과학적 접근

박석범 ( Seok Beom Park ),이경면 ( Kyung Myun Lee ) 한국서양음악이론학회(연세대학교 음악연구소) 2020 음악이론포럼 Vol.27 No.2

음악을 듣는 사람은 종종 음악에 맞추어 몸을 움직이고 싶은 기분 좋은 느낌을 경험한다. 이러한 경험은 서양의 대중음악에서 그루브(groove)라는 용어로 표현된다. 본 논문에서는 그루브 경험에 대한 최근의 인지과학 및 신경과학 분야 논문들의 소개를 통해, 인지과학 분야에서는 그루브를 어떻게 정의하고 있으며, 어떤 방법으로 연구하는지 설명하고, 그루브 경험에 영향을 미치는 것으로 나타난 음악적, 개인적 요인들은 무엇인지, 그리고 기존 연구의 문제점을 바탕으로 향후 그루브 연구의 방향성에 대해 제언하였다. 본 논문은 음악에 대한 신체의 움직임, 음악이 유발하는 즐거움을 인지과학적으로 이해하는데 있어 그루브 경험 기제의 중요성을 강조하고, 앞으로 그루브에 대한 연구가 어떠한 방향으로 나아갈 수 있는지를 제시한다. People often experience a pleasurable urge to move their bodies to the music. This experience is described as the word, groove. By introducing research articles on groove experience in the field of cognitive science and neuroscience, we explain how groove is defined and studied in these fields, what the music-related and listener-related factors important for groove are, and what should be considered in conducting further studies on groove. This paper highlights why cognitive studies on groove are important in order to understand the mechanism of the body movement and emotional responses to music and proposes the future direction of groove research.

UVB 에 의한 홍반반응 및 색소반응의 Dose - response Angle과 피부의 자외선 감수성 지표들과의 상관관계에 관한 연구

김병국,박석범,윤재일 ( Byoung Kook Kim,Seok Beom Park,Jai Il Youn ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.6

Background: There are many predictors of sensitivity to UVR, but controversies exist about their objectivity, correlation bet,ween them, and applicability to various races. Objective : In 42 healthy volunteers, we assessed the validaty of dose response angle of erythe ma(DRAE) and delayed tanning(DRADT) after UVB irradiation, and also evaluated the correlation hetween dose-response angb s and other predictors of UV sensitivity. Methods : We measured erythema and melanin index using reflectance spectrophotometer aft,er irradiation of UVB on the back of 42 males. When the erythema index and melanin index were plotted against UV doses for each patient, a dose response curve was obtained. Linear regression analysis was used to calculate the slope of those curves for erythema and delayed tanning, which were called DRAE and DRADl respectively. Also we checked predictots of UV sensitivity such as skin type, MED, MMD, consiitutional and facult,ative skin color, then analyzed the relation be tween dose response angles and other predictors. Results : Statistically significa it linear regression lines were obtained from 41 subjects regar d- ing to erythema and frorn 31 subjects regarding to delayed tanning. As for the relationship he tween the pvedictors of UV senitivity, only the MED correlated well with DRAE. Conclusion : We found that dose response angles, especially DRAE, were an objective and adequate predictor of cutaneous LJV sensitivity, but could not find validity of skin type and skin color in Koreans. A more organized study with a larger number of subjects is needed to clarify the usefulness of the predictors. (Korean J Dermatol 1997;35(6): 1177-1183)

Calcipotriol-PUVA 복합요법에 의한 건선의 치료

최용범(Yong Beom Choe),박석범(Seok Beom Park),윤재일(Jai Il Youn) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.6

Background:PUVA photochemotherapy has been accepted as an effective treatment modality in the treatment of psoriasis. Many combination therapies have been tried to reduce the long-term side effects of UV radiation. Objective:We performed conventional PUVA and calcipotriol-PUVA combination therapy to compare the effectiveness between two treatment modalities. Methods:We treated 38 Korean patients with conventional PUVA and 54 with D-PUVA. We compared the total number, duration and total UVA dose of PUVA therapy to reach grade 4 between two groups. We categorized each patient into clearing, improvement, or failure groups based on the therapeutic efficacy, and evaluated PASI score at patient`s visits. Results:The irradiation number and total cumulative dose of D-PUVA phototherapy to achieve grade 4 were significantly smaller than PUVA phototherapy. Conclusion:Combining PUVA with a vitamin D analogue, calcipotriol, in the treatment of psoriasis may lead to lowering the risk of long-term exposure to UV radiation with higher efficacy. (Korean J Dermatol 2000;38(6):772~776)

한국인 건선환자의 치료에서 Retinoid, PUVA 단독치료와 Re-PUVA 복합치료의 비교

윤재일(Jai Il Youn),박석범(Seok Beom Park) 대한피부과학회 1999 대한피부과학회지 Vol.37 No.9

N/A Background : Although retinoid and PUVA monotherapy is effective for psoriasis, both treatment regimens have some limitations because of the risk of long-term toxicity. Obejective : We perfomed Re-PUVA combination therapy to evalute the clinical efficacy and safety in comparison with retinoid and PUVA monotherapy. Methods : Seventy-eight psoriasis patients received Re-PUVA combination therapy as well as conventional retinoid and PUVA monotherapy. Pretreatment with etretinate for 1 week was followed by PUVA therapy in combination with etretinate. Results : 1. Among patients who received Re-PUVA combination therapy, clearing was shown in 77.3% and improvement in 13.6%, which were higher than retinoid, 27.8%/61.1%, and PUVA monotherapy, 65.8%/21.0%. 2. In patients who reached grade 4 with Re-PUVA therapy, the duration and total dose of etretinate were 56.4 days and 1616mg. These were significantly lower than retinoid monotherapy, 107.5 days and 2577.5mg. 3. In patients who reached grade 4 with Re-PUVA therapy, the number and total dose of UVA were 13.3 and 82.8 J/cm2, which showed no difference compared with those of PUVA monotherapy, 16.2 and 120.2 J/cm2 However, excluding the cases who did not respond to previous monotherapy, the number and total dose of UVA in Re-PUVA were 10.4 and 49.0J/cm2, which were significantly lower than those of PUVA 4. The side effects of Re-PUVA were reported in 54.5%, which were similar to PUVA monotherapy, 52.6%, and lower than retinoid monotherapy, 83.3%. There were some side effects of retinoid, such as cheilitis,dry mouth, elevation of sGOT/sGPT and triglycerides, and side effects of PUVA, such as itching, erythema, anorexia, nausea and vomiting. Conclusion : Our study suggests that Re-PUVA combination therapy is more effective and tolerable than retinoid and PUVA monotherapy in the treatment of psoriasis, especially in severe and recalcitrant cases. (Korean J Dermatol 1999;37(9) : 1247∼1253)

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

Narrow Band UVB를 이용한 건선의 광치료

윤재일,박석범,최용범 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.3

Background:Narrow-band UVB phototherapy using 311±2nm wavelength is in widespread use due to its greater efficacy and, possibly, safety compared with broad-band UVB sources. Objective:We performed emollient narrow-band UVB(NBUVB) phototherapy to evaluate the clinical efficacy and safety in Korean psoriasis patients. Methods:Fifteen psoriasis patients received narrow-band UVB phototherapy. We categorized each patient into clearing, improvement, or failure groups based on the therapeutic efficacy, and measured the PASI score every two weeks. Results: 1. Among patients who received narrow-band UVB phototherapy, clearing was shown in 40.0% and improvement in 27.7%, and failure in 33.3%. 2. The total number, duration, final and cumulative doses to achieve grade IV were 16.3, 39 days, 1,050mJ/cm2 and 12,125mJ/cm2 respectively. 3. There were some side effects of NBUVB phototherapy such as pruritus(53.3%) and mild burning(13.3%). Conclusion:Narrow-band UVB phototherapy is a effective treatment modality which is convenient and less erythemogenic in psoriasis. It will be used more and more and play an important role in the treatment of psoriasis.

건선에서 병발한 유전분성 태선 1예

윤재일,박석범,김상덕 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.7

Psoriasis is merely recognized as a disorder associated with pruritus. But in some cases, psoriasis does induce pruritus which could alter the daily lives of the people affected. Pruritus in psoriasis has been reported to be influenced by various external and internal factors and as a consequence, aggravation of psoriasis is possible by scratching due to the well-known Koebners phenomenen. Lichen amyloidosis, on the other hand, appears as multiple papules with intense pruritus. Recently, there are some evidence emphasizing pruritus as a main factor in forming amyloid deposits. We report a case of 65-year-old lady who was suffering psoriasis for 25 years with associated pruritic papular lesions on both of her thighs, knees and ankles. The diagnosis of Lichen amyloidosis was confirmed by Periodic Acid Schiff and Dylon stain. We discuss the role of pruritus in lichen amyloidosis and psoriasis and speculate that pruritus induced by lichen amyloidosis may induce a vicious cycle in aggravating psoriasis.

광과민 건선 2예

윤재일,박석범 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.1

Photosensitive psoriasis is a rare disease defined as psoriasis in which the lesions deteriorate or new lesions develop after sun exposure. It should be differentiated from other photosensitive conditions that may be a vated or confused on sun-exposure. Half of the patients have a history of polymorphic light eruption(PMLE), whieh several weeks later develops into psoriasis lesions and the others have no history of preceding PMLE reaction. PUVA therapy is recommended for the treatment of choice. In this report, we describe two cases of photosensitive psoriasis. A 51-year-old woman without underlying psoriasis suffered from erythemato-squamous papular lesions on the face, neck and dorsum of hands after sun-exposure. She revealed a lowered minimal erythema dose(MED) for UVA which was confused with a photosensitive disease. But characteristic psariatic plaques on the elbow, knee and palm and histologic findings made the diagnosis photosensitive psoriasis. She showed a good result to cyclosporine therapy. The other patient, a 44-year-old woman with underlying psoriasis, experienced an exacerbation with preceding PMLE and showed a lowered erythema threshold for UVB. She was treated with sun-screen and topical corticosteroids.