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한국에서의 시신경 수막종 환자의 임상 양상 및 치료 결과
이은경,김성준,백선하,김동규,김일한,곽상인,Eun Kyoung Lee,Seong-Joon Kim,Sun Ha Paek,Dong Gyu Kim,Il Han Kim,Sang In Khwarg 대한안과학회 2011 대한안과학회지 Vol.52 No.1
Purpose: To evaluate the clinical features and treatment results of optic nerve sheath meningioma (ONSM) in Korean patients. Methods: The present retrospective noncomparative case series was comprised of 10 eyes of 10 patients with a diagnosis of ONSM who were treated between 1997 and 2010 at the Seoul National University Hospital. Results: The mean age at presentation was 47.9 years. Two males and 8 females participated in the study. Decreased vision and proptosis were the most common presenting symptoms. On imaging, the most common pattern was tubular. The most common histopathologic pattern was a meningothelial type. Two patients who were observed maintained good vision during the follow-up period and showed a slow progression of the tumor. Two patients out of 3 who underwent surgical management presented significant visual loss and complications. Three patients in the gamma-knife surgery (GKS) group showed no significant changes in visual acuity after treatment; however, tumor growth was halted. Two patients who underwent 3-dimensional conformal radiotherapy (3D-CRT) presented improvement in their visual acuity or visual field, and tumor growth was halted. Conclusions: Management should be conservative in most cases because of the slow and indolent growth pattern of ONSM. However, 3D-CRT can be considered as an initial treatment in patients with progressive visual deterioration and having still higher possibility of vision maintenance. GKS can be indicated in patients with progressive visual deterioration and a rare possibility of visual recovery. Surgical indications for ONSM are limited and must be carefully considered for each patient. J Korean Ophthalmol Soc 2011;52(1):74-85
박종현 ( Jong Hyun Park ),박성환 ( Sung Hwan Park ),김백선 ( Paek Sun Kim ),이준욱 ( Joon Wook Lee ),유완희 ( Wan Hee Yoo ),주영실 ( Yeong Shil Joo ),이신석 ( Shin Seok Lee ),김완욱 ( Wan Uk Kim ),민준기 ( Jun Ki Min ),홍연식 ( Ye 대한류마티스학회 1999 대한류마티스학회지 Vol.6 No.3
Dermatomyositis is a clinical entity characterized by a distinctive cutaneous rash and inflammatory myopathy. In this disorder, the pneumomediastinum is quite a rare complication and is assumed to result from air leakage due to vasculitis, lung fibrosis or rarely after bronchoscopic lung biopsy and pulmonary function test. We describe patient with dermatomyositis who developed pneumomediastinum, pneumothorax and massive subcutaneous emphysema after pulmonary function test. She died due to respiratory failure. We think that careful observation is required in performing PFT in dermatomyositis patients with presumed interstitial lung diseases.
Cushing씨 병 : 16례에 대한 임상분석 및 수술적 치료 결과 Clinical Analysis and Surgical Outcome in 16 Cases
김은상,홍승철,백선하,김동규,정희원,조병규,최길수,한대희 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.1
From March, 1984 to August, 1991. 16 patient were diagnosed as Cushing's disease and 14 of them were treated by transsphenoidal microsurgical procedure. Preoperative endocrinological evaluation included plasma level of ACTH, serum cortisol concentration, urinary free cortisol and 17-hydroxycorticosteroid, dexamethasone suppression test and bilateral sampling of the inferior petrosal sinuses(IPS). The sensitivity of the last method was 88% for Cushing's disease but the expected laterality with the test was not always consistent with the surgical results. High resolution computed tomography(CT) and high field magnetic resonance imaging(MRI) were done as imaging devices. We cannot tell MRI is superior to CT is diagnosing microadenomass. All operations were performed through transsphenoidal approach. A selective microadenomectomy was done in 8 patients and all of them showed remission. A partial adenomectomy was done in 4 cases. Hypophysectomy was done in 2 cases, one of which was a failed case after the first trial and the other was one with no apparent tumor tissue in 7 successive frozen biopsies during operation. Overall surgical remission rate was 86%.