KI-180과 KI-188 칼슘조성물이 어린쥐의 성장발육에 미치는 영향

박승만(Seung-Man Park),성기승(Ki-Seung Seong),이종석(Jong-Seok Lee),이옥환(Ok-Hwan Lee),한찬규(Chan-Kyu Han) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.3

본 연구에서는 KI-188 칼슘과 KI-180 조성물이 성장발육에 미치는 효과를 조사하였다. 시험기간중 KI-188 칼슘과 KI-180 식이군이 대조군 보다 성장률과 평균 식이섭취량은 증가하였다. 체장은 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 평균 3.55 mm 더 길었고, 등뼈길이는 KI-180 식이군이 대조군 보다 통계적인 차이는 없었지만 0.5 mm 더 길었다. 대퇴골 무게는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 무거웠으며, 대퇴골길이는 대조군에 비해 각각 평균 0.89, 1.09 mm 더 길었다. 혈당, 총콜레스테롤 및 중성지방 농도는 차이가 없었고, 칼슘농도는 KI-188 칼슘과 KI-180 식이군 보다 대조군이 유의하게 높았다. 백혈구와 혈소판수는 차이가 없었고, 적혈구, 혈색소 및 헤마토크릿치는 대조군이 KI-188 칼슘과 KI-180 식이군 보다 통계적으로 높았다. ALP활성은 KI-180 식이군이 대조군 보다 통계적으로 높았고, osteocalcin농도는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 유의하게 높았다. 혈청 testosterone 농도는 KI-188 칼슘과 KI-180 식이군과 대조군 간에 차이가 없었다. IGF-1과 IGFBP-3 농도는 KI-180 조성물이 대조군 보다 각각 20%, 11% 정도 유의하게 더 높았다. 이상의 결과를 검토할 때 KI-188 칼슘과 KI-180 조성물은 어린쥐의 성장과 골격의 발달을 촉진시키고, 성장호르몬의 분비능을 양적으로 유도하여 전반적인 성장발육에 유효한 작용이 있는 것으로 사료된다. Herbs have active components that promote the growth rate of both animals and human. The KI-180 and KI-188 calcium food formulae contain Acanthopanacis cortex, Bombysis corpus and hoelen, seaweed calcium, chlorella extract, spirulina, colostrum powder, and other natural and functional components. We evaluated the growth-promoting effects of these formulae by analyzing the weight, femur and backbone, alkaline phosphatase, osteocalcin, testosterone, insulin-like growth factor (IGF)-1, and IGF binding protein-3 (IGFBP-3) of growing rats. Growing rats administered with KI-180 and KI-188 calcium showed the increase of body weight, body length, and femur weight and length of growing rats. In addition, administration of KI-180 and KI-188 calcium increased the alkaline phosphatase activity, the levels of osteocalcin and the growth hormones IGF-1 and IGFBP-3 of growing rats. The impact of KI-180 and KI-188 calcium on the physical development of growing rats suggests that the incorporation of these food formulae in the diets of growing children may promote the physical development.

대학 운동클럽(Club)학생들의 체형. 신체구성에 관한 연구

한기문,박승옥 광운대학교 기초과학연구소 1997 기초과학연구소논문집 Vol.26 No.-

The purpose of this study is to find the somatotype and body composition of the students in sports clubs in our school, and the subjects of study are 169 students in all including 68 students in sports clubs(16 in table tennis club, 12 in tennis club, 14 in basketball club, 12 in keumdo club), 53 non-sports club students and 48 common students. The result of data analysis is as follows. 1. Somatotype The mean somatotype of the group in table tennis club is found to be endomorphic mesomorph of 3.59-4.51-3.10, that of the group in tennis club ectomorphic mesomorph of 2.97-4.67-3.18, that of the group in basketball club endomorphic mesomorph of 3.88-4.62-2.77, that of the group in baseball club endomorphic mesomorph of 4.13-4.81-2.12, and that of the group in keumdo club ectomorphic mesomorph of 2.98-4.35-3.20. The mean somatotype of all the group is found to be endomorphic mesomorph of 3.37-4.37-1.26. 2. Absolute Fat 1) % Fat The average of the group in table tennis club showed 18.97%, that of the group in tennis club 16.11%, that of the group in basketball club 19.83%, that of the group in baseball club 21.41%, that of the group in keumdo club 15.51%. 2) Absolute Fat The average of the group in table tennis club showed 12.51kg, that of the group in tennis club 10.02kg, that of the group in basketball club 13.83%, that of the group in baseball club 14.85kg, that of the group in keumdo club 9.98kg. 3. The comparison of the group in sports club with the group in non-sports club. The comparison of the two groups in somatotype showed that the group in sports club is much higher(p〈0.05) than the group in non-sports club in mesomorphic components. The comparison of absolute fat showed that the group in sports club is much more than the group in non-sports club only in lean body mass, and didn't show any striking difference in other components.

횡성군에서의 자살에 관한 연구

박기창,한정옥,유계준 大韓神經精神醫學會 1985 신경정신의학 Vol.24 No.2

An epidemiologic and psychiatric studies about suicides in Whoeng-Sung county for the past 7 years from January 1, 1977 to December 31, 1983 were conducted in order to identify overall pictures of suicides committed in this area. All the suicidal cases were obtained from the records of Whoeng-Sung police station. The authors visited homes of suicide victims and interviewed the family members, the relatives and the neighbors. The total number of suicides committed in this area during the study period was 123, and the suicidal rate was 23.4 per 100,000 population. The number, excluding the inhabitants outside this area, was 109, and the rate was 20.7 per 100,000 population. The male to female ratio was 2 to 1 and the highest rates were shown in the age group of 50-59 for male and 20-29 for female. Also, higher rates were shown in lesser educated, lower economic class, and people of Buddism and Confucianism. The main method for suicides, accounting for 76.2% of the total, was by ingestion of herbicides and insecticides for farming purposes. The place selected for the suicide was usually at victim's own house (67.9%). 82.4% of the victims have previously suggested their intention to commit suicide and of the victim have left a will. Also the suicidal rate was highest in the summer, higher in the afternoon, and higher in the beginning of the week for the male. Single men showed the highest suicidal rate. The common precipitating factors of committing suicide were family trouble, chronic illness or disability and financial difficulty. The most apparant dynamic motives of the suidides was easy self-abandonment of one's own life. Most of the suicidal victims had some psychopathologic condition (91.6%).

농업구조물의 안전진단 및 개·보수 공법 선정 시스템 개발

김종옥,고만기,최진용,김기동,윤광식,김한중 公州大學校 産業開發硏究所 1998 産業開發硏究 Vol.6 No.-

A study was conducted to develope a system for safety appraisal and repair works on agricultural structures. Location, size, type, maintenance record, structural and functional problems of agricultural structures in Yedang irrigation district were surveyed. A grahpic user interface program assisting onsite field investigation of typical agricultural structural problems such as fractures and cracks of members was developed. Typical rehabilitation methods were investigated and coded for database development.

다변량통계분석을 이용한 수질오염총량관리 단위유역별 오염물질 배출특성 분석 -한강수계를 중심으로-

최옥연 ( Ok Youn Choi ),김기훈 ( Ki Hoon Kim ),한인섭 ( Ihn Sup Han ) 한국물환경학회 2015 한국물환경학회지 Vol.31 No.6

The characteristic of the water quality and pollutant discharge was analyzed at the units watershed of the total amount management in Han-river basin, and after classified in a similar area by multivariate statistical analysis, the main trend such as the water quality trend and pollutant discharge characteristic were analyzed. As a result of this study, the density of the pollutant at the unit watershed is not necessarily identified as discharge density, and the primary management watershed and targeted substances were analyzed depending on the operating status of the environmental infrastructure in watershed and the main pollution factor and discharge path per pollutants. As a result of cluster analysis, watersheds were classified into four groups according to discharge characteristics. It will be used when selecting target area of primary management that is appropriate to the characteristics of each river and establishing efficient water quality improvement plans.

청반손상 후에 L-dopa 를 투여한 쥐에서 나타나는 주의장애

조옥경,한정수,김기석 한국심리학회 1989 한국심리학회지 생물 및 생리 Vol.1 No.1

도파민 효능제인 L-dopa를 쥐에게 투여하면 강화와 짝지어지지 않은 부적절자극을 무시하는 주의 과정에 장애가 나타난다. 이같은 장애는 청반을 파괴하여 대뇌 노어에피네프린계의 이상을 초래한 경우에도 나타나므로 청반손상 후에 L-dopa를 투여하면 주의장애가 심해질 것으로 예상하였다. 왕복상자에서 회피반응을 쥐에게 학습시킨 후 검사시행에서는 훈련에 사용되었던 소리자극을 전기쇼크없이 제시하는 중간중간에 부적절자극인 빛자극을 무선적으로 제시하였다. 실험 결과, L-dopa집단이 주의장애를 보였고 청반손상집단은 주의장애가 없었으나 청반손상과 L-dopa 투여가 같이 처치된 집단은 부적절자극을 무시하는 능력에 상당한 장애를 보였는데 이는 L-dopa 단독 투여 효과를 훨씬 넘어서는 것이었다. 이같은 결과는 주의과정에 도파민과 노어에피네프린이 상호작용할 가능성을 시사하며 이는 정신분열증 환자에서 나타나는 주의장애에 대한 동물모형을 제시해 줄 수 있다고 생각된다. The attentional process by which animals learn to ignore an irrelevant stimulus was examined after the treatment with L-dopa or bilateral electrolytic lesions of locus coeruleus(LC). Rats received daily 100 trials of two-way avoidance training in which each trial was initiated by a 10-sec tone stimulus and terminated either by a shuttle response during the tone(avoidance) or by a response during the electric shock(escape). The training sessions continued until the animals met a criterion of eight avoidance responses during any ten consecutive trials. The same rats then received a 50 trials test session. A light, which was irrelevant because it had never been paired with shock, was randomly presented during the test period. The administration of L-dopa produced marked impairment in tuning out the irrelevant stimulus, but LC lesion group did not show any attentional deficits. When L-dopa injection was superimposed to LC lesions, the deficit was increased. It may be interpreted that the result is due to an interaction between the noradrenergic and dopaminergic system. This interaction in ignoring an irrelevant stimulus may provide an animal model of selective attention deficit observed among some schizophrenic patients.

요로결석 환자의 체외충격파쇄석술 치료경과와 결석 특성과의 관련성

김성길,김기순,류소연,한미아,이선옥,노준 朝鮮大學校 附設 醫學硏究所 2009 The Medical Journal of Chosun University Vol.33 No.S

요로 결석에 대한 비 침습적 치료 방법인 체외충격파쇄석술에 의한 치료경과와 결석 특성과의 관련성을 파악키 위해 2002년 12월부터 2008년 3월까지 G시 H병원에서 요로 결석으로 진단되어 체외충격파쇄석술을 받은 33l례를 대상으로 의무기록 자료를 이용하여 분석한 결과는 다음과 같다. 1. 조사 대상자 331례중 남자는 68.6%, 여자는 31.4%이었으며 평균연령(표준편차)은 44.2 (13.9)세 이었고 84%가 G시내 거주자였다. 2. 조사 대상자에게 시행된 체외충격파쇄석술의 평균 시술횟수(표준편차)는 1.9(1.5)회 이었으며 평균 통증제거기간(표준편차)은 3.2(2.1)일 이었고 요로결석 진단 시로부터 치료가 완료되었다고 의사가 판정했을 때까지의 치료기간의 평균(표준편차)은 10.3(8.4)일 이었다. 3. 시술횟수에 통계적으로 유의하게(P<0.01) 관련된 요인은 결석크기, 결석의 방사선 투과성, 요관 폐색여부 이었으며 모형의 설명력은 13.5%이었다. 4. 통증제거기간에 통계적으로 유의하게(P<0.01) 관련된 요인은 결석의 방사선 투과성 이었으며 모형의 설명력은 7.4%이었다. 5. 치료기간에 통계적으로 유의하게(P<0.01) 관련된 요인은 결석크기와 결석의 방사선 투과성 이었으며 모형의 설명력은 13.5%이었다. 따라서 결석의 크기가 크거나 결석이 방사선에 비 투과성일 때, 요관이 폐색되어 있을 때 치료경과가 늦게 됨으로 이러한 사실을 참고 하여 추후 진료지침을 작성 시 보다 효과적이고 효율적인 치료법을 적용할 필요가 있다고 판단되며 보다 체계적인 평가와 연구가 필요할 것이다. Objectives & Methods: To find the treatment process by extracorporeal shock wave lithotripsy (ESWL) and its related stone characteristics in urinary tract stone patients, an analysis was done from medical records of 331 cases who were treated by ESWL from December 2002 to March 2008 at H hospital in G city. Results: Among 331 study subjects 68.6% were male and 31.4% were female. Their mean age (standard deviation, SD) was 44.2 (13.9) years old and 84.0% lived in G city. Average frequency of ESWL done toward study cases were 1.9±1.5 times. Mean duration of disappearance from pain was 3.2±2.1 days and total treatment period for a stone was 10.3±8.4 days. Statistically significant (p<0.01) stone and urinary tract characteristics related with frequency of ESWL were stone size, radio-opacity of the stone, and obstruction of urinary tract. The model composed of these 3 independent variables explained 13.5% of frequency of ESWL. Statistically significant (p<0.01) variable related with disappearance from pain was radio-opacity of the stone, and this model explained 7.4%. Statistically significant (p<0.01) variables related with treatment duration due to stone were stone size and radio-opacity of the stone. These two variables explained 13.5%. Conclusion: The bigger the size of stone are, the slower the treatment process will be. And when the stone is radio-opaque and urinary tract is obstructed, the treatment process will be slower than stone is radio-luscent and urinary tract is not obstructed. So to make effective and efficient treatment manual for ESWL, above fact must be considered and continuous systematic evaluation and research toward ESWL are necessary.

학교체육 활성화 방안에 대한 연구(Ⅰ) : 강원대학교 교양체육 운영방법의 개선을 중심으로

이광재,문병용,노성규,박기동,홍관이,한상준,유옥재,엄기진,정청자,오수일,김윤래,박장평,부기원 江原大學校附設 體育科學硏究所 1986 江原大學校附設體育科學硏究所論文集 Vol.- No.11

Try to find a scheme for activation to College Physical Education, this Report informs the various kinds of Survey and process those were projected for improvement of management methods on Cultural Physical Education in Kang Weon National University. From experimentally carried out "Sports events Choosing System" not as usual be inforced "Total practical Skill System", Following Positive effects and sujestions were Presented; 1. "Sports events choosing system" gave birth to more students' interesting and more voluntary participation to the sports events they chose, and sports skill and instruction level was elevated due to charge of expert according to each sports events. This system would be managed continuously hereafter for it related to life sports. 2. This System needs to closed cooperations between College and Community, for the facilities of community are utilized by college. 3. To complete the plan for activation of college Physical Education, additionally, the successional study ; namely "autonomous extracurricular sports activity" should be excuted hereafter.

HFC-134a와 대체냉매 HFC-152a에 CF_3I를 혼합한 자동차냉매 특성

권일욱,박찬수,홍경한,문기선,최운수,서의경,윤갑식,이종인,하옥남 朝鮮大學校 機械技術硏究所 2002 機械技術硏究 Vol.5 No.1

These days, an attention of environment has been increasing all over the world. to prevent the green house effect and destruction of an ozone layer, an ozone destruction potential(ODP) be zero and a refrigerant for low global warming potential(GWP) is needed. HFC-134a, in which hydrogen is mixed instead of chlorine is a refrigerant used for automobile conditioners and its destruction potential is ecologically zero. However, it is not considered as a perfect substitutive refrigerant as its GWP is high. It is studied refrigerant mixtures in which HFC-134a, HFC-152a and CF_3I with low GWP and zero ODP are mixed by experimentally and concluded as follows; 1. with the variation of speed of compressor outside temperature and flow rate, the heat of evaporator and compressor and coefficient of performance was varied, and influenced the air conditioner. 2. The pressure of evaporator was decreased with increasing the speed of compressor and that of the refrigerant HFC-134a was higher 21% than that of azotrope refrigerant mixed with CF_3I. The overall capacity of condensor and evaporator was increased and HGC-134a was higher than azotrope refrigerant mixed with CF_3I 3. The capacity of evaporator with the refrigerant HFC-134a was higher 6% than azotrope refrigerant mixed with CF31 and the required power with zaotrope refrigerant mixed with CF_3I was higher 11% than that of HFC-134a. 4. The COP of the refrigerant FHC-134a was higher 31% in 1000RPM. when outside temperature was increased, COP was decreased. 5. Performance of HFC-134a is better than azotrope refrigerant mixed with CF_3I but prefered zaotrope refrigerant mixed with CF_3I considering the environment.

Studies on the anti-inflammatory activity of aralia continentalis (II)

Han, Byung-Hoon,Han, Yong-Nam,Han, Ki-Ae,Park, Myung-Hwan,Lee, Eun-Ok The Pharmaceutical Society of Korea 1983 Archives of Pharmacal Research Vol.6 No.1

By tracing albumin stabilizing activity an anti-inflammatory component, continentalic acid was isolated from ether-soluble acidic fraction of Aralia continentalis. Continenetalic acid in a concentration of 0.115mg/3ml gave 50% inhibition for heat denaturation of albumin. The protein stabilizing potency of it was approximately three and eleven times that of phenylbutazone and that of salicylic acid, respectively. The anti-inflammatory actions of it and its methylester were investigated employing carrageenin-induced edema in rat paw. Continentalic acid administered s. c. showed an activity of about three times of hydrocortisone. When administered p. o., it was still active, but its methylester was more active than phenylbutazone, suggesting the poor absorption of it in gastorointestinal tract. Its chemical structure was identified by chemical and spectral studies as (-) pimara 8(14), 15-diene-19-oic acid, which was already isolated from A. dordata, but not reported for its biological activity.