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      • KCI등재

        쌀의 수침시간 및 증자시간에 따른 가래떡이 품질 특성

        유진현,한규홍 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.6

        The effects of soaking and steaming time on the quality characteristics of Korean rice cake (karedduk) were investigated. As the soaking time increased, the water-binding capacity and rice floor solid content also increased. After 8 to 10 hr soaking, 75.2 to 76.8% of particles were smaller than 40 gm, and 23.2 to 24.8% within the range of 40 to 100 ㎛. Therefore, an extended soaking time reduced the particle size. Texture is an important characteristic used to differentiate karedduk varieties, and is considered by the consumer as a determinant of the overall quality and preference. The hardness, cohesiveness, gumminess and chewiness of the karedduk structure decreased with increasing steaming time, but the springiness was highest after a 40 min steaming time. The overall texture properties were also more acceptable with 8 and 10 hrs soaking times. The L value of the karedduk decreased with increasing steaming time, but the b value increased. Also, the results of the sensory evaluation showed that an 8 hr soaking time and 40 min steaming time produced more acceptable karedduk in terms of whiteness, texture, springiness, chewiness and overall acceptability.

      • 양방향 요소제거법을 이용한 신뢰성 기반 최적설계

        유진식,박재용,황승민,임민규,오영규,한석영 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

        This research presents a Reliability-Based Topology Optimization (RBTO) using Bi-directional Evolutionary Structural Optimization (BESO). An actual design involves uncertain conditions such as material property, operational load and dimensional variation. Deterministic Topology Optimization (DTO) is obtained without considering of uncertainties related to the uncertainty parameters. However, RBTO involves evaluation of probabilistic constraints, which can be done in two different ways, the reliability index approach (RIA) and the performance measure approach (PMA). The reliability index approach (RIA) and the performance measure approach (PMA) are adopted to evaluate the probabilistic constraints. In order to apply the BESO method to the RBTO, sensitivity number is defined as the change in the reliability index due to the addition or the removal of the ith element. In the BESO, a mesh-independency filter using nodal variables is used to remove the checkerboard patterns. The optimal topologies of RIA and PMA are obtained very similarly. It is shown that RBTO based on BESO can be effectively applied from the presented examples.

      • 렌즈의 자동초점 구동을 위한 리니어 초음파 모터

        김유민, 이한주, 오진헌, 임기조 충북대학교 컴퓨터정보통신연구소 2012 컴퓨터정보통신연구 Vol.20 No.1

        In this paper, a novel type ultrasonic linear motor is proposed. The proposed motor consists of a ring type stator and a mover. They have spirals on their inner and outer surface, respectively. Along the spiral, a mover is travelled by a travelling extensional vibration mode of a ring type stator. Hence, a linear up-and-down motion is possible. Through the experimental results, we can verify the applicability regarding the autofocus lens driver. keywords : Ultrasonic linear motor, Autofocusing driver, ring type stator

      • KCI등재후보

        대량의 각혈로 사망한 장티푸스 1예

        한상우,유진홍,권순석,김성훈,박지찬,홍은정,최경성,박용완,장준희,안지원,박유경,강지영,박상미,신완식 대한감염학회 2004 감염과 화학요법 Vol.36 No.5

        We experienced a 25 year-old male patient with typhoid fever complicated with massive hemoptysis. Pulmonary complication in typhoid fever is very rare and to our knowledge, there has been no report of hemoptysis as a main cause of death with this disease. We herein report a rare case of typhoid fever.

      • KCI등재

        Four new compounds from the bulbs of Lycoris aurea with neuroprotective effects against CoCl2 and H2O2-induced SH-SY5Y cell injuries

        An Jin,Xuelian Xiang,Yun-Yun Zhu,Heng-Yi Yu,Hui-Fang Pi,Peng Zhang,Han-Li Ruan 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.3

        Three new alkaloids, 2a-hydroxy-6-O-n-butyloduline,O-n-butyllycorenine, (-)-N-(chloromethyl)lycoramine(1–3), and a new phenolic compound, ((7S)-7-(4-hydroxyphenyl)-7-hydroxypropyl)-20-methylbenzene-30,60-diol (14), along with ten known alkaloids (4–13), wereisolated from the bulbs of Lycoris aurea collected fromHuaihua County of Hunan Province, China. Their structureswere elucidated by spectroscopic methods includingHRESIMS, UV, IR, and NMR. All the isolated compoundswere tested for their neuroprotective effects against CoCl2and H2O2-induced SH-SY5Y cell death. Compounds 1–7and 10 exhibited significant neuroprotective effects againstCoCl2-induced SH-SY5Y cell injury, while compounds1–5, 7, 10 and 12 showed obvious neuroprotective effectsagainst H2O2-induced SH-SY5Y cell death.

      • 활성탄에 의한 카페인 및 니코틴의 흡착특성

        손진언,이성식,김달한,유명호,이만식 동아대학교 환경문제연구소 1994 硏究報告 Vol.17 No.1

        Adsorption equilibrium and kinetics of Caffeine and Nicotine from aqueous solution on activated carbon were determined experimentally in a batch system. Then, the equilibrium data were expressed by the Freundlich type and the equilibrium constants were obtained. Diffusion coefficient were determined by comparing experimental decay curve with theoretical ones. Surface diffusion was consided to be dominant and the value of diffusion coefficient were depent of the amount adsorbed and the equilibrium concentration. Domestic activated carbon has nearly same amount of adsorption as imported activated carbon made by CALGON carbon Corp.

      • KCI등재

        AE기법 이용한 JLF/STS304이종재료의 최적 마찰용접조건에 관한 연구

        윤한기,이진경,이상필,공유식 한국비파괴검사학회 2003 한국비파괴검사학회지 Vol.23 No.2

        저방사화 페라이트강인 JLF는 핵융합로의 블랑켓과 같은 열교환기의 재료로써 유용한 재료이다. 이 재료의 광범위한 적용을 위해서는 JLF강과 다른 재료와의 접합기술의 개발이 중요하다. 최근 두 이종재료간의 접합에는 마찰용접이 많이 이용되고 있으며 본 연구에서도 JLF강과 STS304 간의 마찰용접에 의한 용접특성을 평가하였으며 특히 비파괴기법중의 하나인 음향방출 기법을 이용하여 두 이종재료간의 용접특성 및 최적의 용접조건을 평가하였다. 음향방출 파라미터중의 하나인 카운트와 사상수 등이 최적용접조건 및 용접품질을 평가하는데 유효한 파라미터들이었다. Japanese low activation ferritic steel(JLF) is a good material for the parts of heat exchanger such as blanket and diverter. At first, JLF was developed as a candidate for structural materials in nuclear fusion applications. However, the development of the jointing technique of JLF steel to other materials is important for wide applications of this material to the industry fields. Recently the jointing technologies including diffusion bonding, brazing, roll bonding, explosive bonding and hot iso-static pressing have been studied for the heterogeneous materials of JLF-1 steel(Fe-9Cr-2W-V-Ta) and stainless steel(STS304). Friction welding is one of the most popular welding methods for two different kinds of materials. In this paper, the JLF-1 steel was jointed to STS304 by friction welding method and the optimal conditions of the friction welding discussed. Acoustic emission was used as a nondestructive technique to evaluate the weld quality in processing.

      • KCI등재

        정신분열병과 Neurotensin 수용체 유전자 다형성의 연합 연구

        이유상,김형배,한진희,채영규,이정식,이혜순,주연호,김형섭,최인근,양병환 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

        연구목적: Neurotensin(NT)은 NT수용체와 결합하여 그 효과를 나타내는 neuromodulator 혹은 neurotransmitter로서 대뇌에서 도파민의 분비를 조절하는데 중요한 역할을 한다. 근래의 연구에 의하면 NT와 그 수용체는 대뇌에서 항정신병 약물의 효과를 매개하는 것으로 생각되고 있으며 약물치료를 받지 않은 정신분열병 환자의 뇌척수액에서 NT의 양이 적으로 보고되고 있어 이들은 정신분열병과 깊은 관련을 가지고 있을 것으로 추정된다. 최근 NT수용체의 유전자의 3`인접영역에서 정보가치가 높은 4 염기반복 다형성이 발견되어 이를 유전 표지자로 하여 정신분열병과의 연합을 알아보았다. 방 법: 서로 혈연관계에 있지 않은 정신분열병 환자 120명(남자 91명, 여자 29명)과 정상 대조군 106명(남자 84명, 여자 22명)을 대상으로 하였다. PANSS를 사용하여 양성 및 음성을 알아보았다. 말초혈액에서 DNA를 분리한 후에 중합효소연쇄반응을 사용하여 3`인접영역에 있는 4 염기 반복 다형성을 증폭하였고 silver staining한 후에 유전자형을 관찰하였다. chi-square 검증과 Bonferroni`s correction을 사용하여 환자군과 정상 대조군간의 대립유전자 빈도의 차이를 알아보았다. 또한 양성 및 음성 환자군으로 나누어 차이를 알아보았다. 결 과: 총 23개의 대립유전자가 관찰되었으며, 399bp의 대립유전자(A10)의 빈도가 환자군보다 정상대조군에서 통계적으로 유의하게 높았다(χ²=16.49, df=1, p<0.001). 음성 정신분열병 환자군과 정상대조군 사이의 비교에서는 정상대조군의 A10의 빈도가 환자군보다 유의하게 높았다(χ²=21.33, df=1, p<0.001). 성별 비교에서 남자 정신분열병 환자군은 대조군에 비하여 A10의 분포가 유의하게 적었다. (χ²=13.71, df=1, p<0.001) 결 론: NT 수용체 유전자와 정신분열병사이에 음성연합이 관찰되었다. NT 수용체 유전자가 일부 정신분열병의 발병과정에서 확실하지는 않지만 어떤 종류의 보호기능을 할 수도 있다는 것을 암시한다. Objectives: Neurotensin(NT), of which functions are evoked by its interaction with neurotensin receptors(NTR), coexists with mesolimbic dopamine and regulates endogenous dopamine release. Recent studies have shown that NT with NTR exerts neuroleptic-like activity within the central nervous system and may play an important role in the pathogenesis and in the treatment of schizophrenia. We have examined the gentic association between schizophrenia and tetranucleotide repeat polymorphism in the 3-flanking region of the NTR gene to investigate the possible contribution of the NTR gene to the schizophrenia susceptibility. Methods: Among 23 alleles identified, the subjects were 120 patients(male 91, female 29)with schizophrenia and 106 normal healthy controls(male 84, female 22). They were unrelated native Korean. PANSS was used to determine positive or negative subgroup in the schizophrenic patients. Using polymerase chain reaction and polyacrylamide gel electrophoresis, tetranucleotide repeat polymorphism(CCTT and CTT) in the 3`-flanking region of NTR gene was observed. For a comparison of NTR gene`s allelic frequencies between patients with schizophrenia and normal healthy controls, chi-square test and Bonferroni`s correction was performed. Results: The frequency of A10 allele(base pair size=399)was significantly higher in normal healthy controls than schizophrenia(χ²=16.4902, df=1, p<.000). In the comparison between schizophrenic patients with negative symptoms and normal controls, the frequency of A10 allele was significantly higher in normal healthy control subjects than patients with schizophrenia(χ²=21.33, df=1, p<0.001). In the case of male, the frequency of A10 allele of schizophrenia was significantly higher than normal controls(χ²=13.71, df=1, p<0.001). Conclusions: NTR gene was negatively associated with schizophrenia. NTR gene`s tetranucleotide repeat polymorphism may provide some protective function against schizophrenia.

      • 도시 노숙자의 주요 정신장애에 관한 역학 연구

        안준호,홍진표,유제춘,박종익,이철,한오수 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.2

        외환위기 이후 대도시를 중심으로 노숙자들이 급증하여 이들이 심각한 사회문제로 등장하였다. 외국의 연구에 의하면 노숙자 중 상당수가 만성 정신질환을 앓고 있으며, 정신질환이 노숙의 원인 및 예후와 밀접한 관련이 있다고 한다. 그러나 국내에서는 아직 노숙자의 정신장애의 유병률에 관하여 알려진 바 없으므로 이에 대하여 조사하였다. 방법: 1998년 말부터 1999년 초까지 부산지역의 쉼터 두 곳에 거주하는 노숙자 216명을 대상으로 인구학적 자료에 대한 설문조사를 한 뒤 Structured Clinical Interview for DSM-Ⅳ(SCID)을 이용하여 Axis Ⅰ의 주요 정신장애를 진단하였다. 이들의 정신장애의 평생유병률 및 현재유병률을 국내 일반인구 및 외국 노숙자의 정신장애의 유병률과 비교하였다. 결과: DSM-Ⅳ Axis Ⅰ의 정신장애 중 기분장애, 정신병적 장애, 물질사용장애에 대한 진단 평가 결과 상기 정신장애의 전체 평생유병률은 60.1%, 현재유병률은 35.7%이었다. 그 중 주요우울장애의 평생유병률 이 22.5%로서 외국의 노숙자에 대한 역학연구 결과와 비교해 볼 때 높은 수준이었고 알코올 사용 장애의 평생유병률은 47.4%이었다. 정신병적 장애의 평생유병률은 3.8%이었고, 그 중에서도 정신분열병의 평생유병률은 1.9%이어서 외국의 노숙자에 대한 연구결과보다 낮은 편이었다. 결론: 국내 노숙자에서 기분장애와 물질사용장애가 주된 정신장애였으며 정신분열병 등 정신병적 장애의 유병률은 외국에 비해 낮은편이었다. 이러한 정신장애를 가지고 있는 노숙자에 대하여 접근하고 치료하기 위한 대책이 마련되어야 할 것이다. Objective:As homeless people increased in urban areas after the economic crisis in Korea, they became a serious social problem. Foreign research showed that many homeless people had chronic mental illnesses which were closely related with the cause and prognosis of homelessness. But very little was known about the prevalence of mental disorders in Korean homeless people. This study tried to capture the overall picture of mental disorders in homeless people. Method:The study subjects were 216 homeless people who stayed at two Pusan shelters between late 1998 and early 1999. Questionnaires on sociodemographic data were administered to the subjects, and then diagnoses of major DSM-IV Axis I mental disorders were made using Structured Clinical Interview for DSM-IV Axis I Disorders(SCID). The lifetime and current prevalence of mental disorders in this study were compared to those from other studies in Korean general population and in foreign homeless people. Results:The lifetime prevalence of major DSM-IV mental disorders(mood disorders, psy-chotic disorders, and substance use disorders) of 216 homeless people was 60.1%, and current prevalence was 35.7%. The lifetime prevalence of major depressive disorders was 22.5% which was higher than that of foreign studies. The lifetime prevalence of alcohol use disorder was 47. 4%. The lifetime prevalence of psychotic disorders was 3.8%, and among them the lifetime prevalence of schizophrenia was 1.9% which was lower than that of foreign studies. Conclusions: In Korean homeless people, mood disorders and substance use disorders were the main mental disorders and psychotic disorders such as schizophrenia were less than in foreign homeless people. The plans to approach and treat homeless people with mental disorders should be made.

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