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      • 뇌실외 배액술 관리에 대한 이해 및 업무수행 실태

        김정숙,윤미선,송소이,이지은,문경선,고지운,임분남,김경희,박경숙 중앙대학교 간호과학연구소 2001 중앙간호논문집 Vol.5 No.2

        The objective of this study was to investigate the managing realities of EVD and provide a descriptive survey with the attempt to obtain basic data needed for the standardization of EVD management. For that purpose, 220 questionnaire copies were distributed to those nurses who were working with intensive care units at university hospitals, general hospitals, semi-general hospitals in Seoul, Kyongki-de and local areas. Of 158 returned questionnaire copies, 139 were used for analysis. Data were collected during the term of academic seminars of Neurosurgery Nursing Committee and KICA (Korea Intensive Care Association), ranging from Oct. 26 through 27. 2000. The tools utilized a structured questionnaire form consisting of 21 questions on general characteristics, the level of understanding, the level of work performance, standard management guidelines, etc. The data collected were analysed with frequency, percentage, mean vague, chi -square test using the SPSS 10.0 program Findings were revealed, as follows: For managing the prevention of EVD infection, aseptic technique was found to be of the most importance (48.9%),'the technique should be carried out at an operation room'(92.8%), but it was actually performed at intensive care units (over 51.5%). 'The term of antibiotics use should be less than 7 days' (81.8%), while it was actually executed for less than 7 days (49.5%). 'The proper time of quittance from it should be within less than 7 days'(74.1%) but actual quittance was executed only by 51.1%. 'Set exchange is needed' by 54.0% but actual exchange was implemented merely by 28.1%. 'The subject of management should be nurses' was reflected by 40% but actually 52.0% were carried out. As a result of hating analysed the understanding of the management of EVD by general characteristics, a significant difference was found in the necessity for set exchange by hospitals, in the time of quittance of a catheter, and in ablution items by work experience. The result of hating analysed the work performance levels of EVD management by general characteristics revealed that a significant difference in administration facilities of medicine by the classification of hospitals, especially the use of antibiotics and the quitting time of a catheter by the classification of intensive care units, and in the use of antibiotics and ablution items by the standard management guidelines.

      • Preparation and properties of new polyurethane gels with a stress-distributing function for medical applications

        Cha, Gook Chan,Lee, Sukmin,Song, Jeom Sik,Kim, Jong Kwon,Kim, Kyung Hoon,Mun, Mu Seong,Youn, Hyoung Soon,Pyun, Do Gi,Choi, Yoon So Wiley Subscription Services, Inc., A Wiley Company 2006 Journal of applied polymer science Vol.100 No.4

        <P>The purpose of this study is to prepare new polyurethane gels that can be used as stress- or pressure-distributing materials, particularly by being combined with selective plasticizers for medical or clinical applications. Because low-molecular-weight plasticizer molecules in polymer gels intrinsically tend to migrate to the surface of the gels by the so-called entropy effect in polymer miscibility, the stress-distributing function may decrease gradually after a certain amount of time. Correspondingly, both the chemical nature of the plasticizer and polymer gels and the compatibility between the polymer segments and plasticizer should be deliberately considered as important factors in determining the thermophysical properties and stress-distributing performance of polymer gels. New polyurethane gels comprising separated phases of soft and hard segments, the glass-transition temperature of which was around the ambient temperature, were prepared, and selective plasticizers were combined to obtain an optimized formulation of gels for stress-relieving properties. The glassy-to-rubbery transition of semicrystalline hard segments occurring around the ambient temperature caused the rearrangement of chain conformations, leading to the reduction of the pressure applied to the surface; this indicated that the pressure buildup or loss was somewhat related to the heat regulation by thermal absorption and release in the phase-transition range. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 100: 2750–2758, 2006</P>

      • KCI등재

        취학전 어린이의 상악 유전치 우식증과 관련 요인

        정승열,이광희,라지영,이동진,안소연,김지영,송지현,김윤희 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.4

        연구 목적은 상악 유전치 우식증의 발생 요인을 규명하기 위함이었다. 연구대상은 익산시 어린이집 중에서 무작위로 추출 한 7개 어린이집의 36개월 이상 71개월 미만의 남아 214명, 여아 187명, 모두 401명이었다. 연구방법은 상악 유전치 우식 증의 유병률을 조사하고, 성별, 연령, 모유 수유 또는 인공 수유, 수유 기간, 감미 간식 섭취 빈도, 칫솔질 시작 시기, 1일 칫솔질 횟수 등을 조사하여 상악 유전치 우식증과의 연관성을 분석하였다. 연구결과를 보면, 상악 유전치 우식증의 유병률은 남아에서 43.0%, 여아에서 26.7%로서 남아가 여아보다 유의하게 높았고(P<0.01), 수유 기간 2년 이하 군에서 31.0%. 2-3 년 군에서 43.2%, 3년 이상 군에서 63.2%로서 수유 기간이 길어질수록 유의하게 증가하는 경향을 나타내었으며(P<0.01), 감미 간식을 매일 섭취하는 군에서 44.2%,2-3일에 한 번 섭취하는 군에서 31.47%, 자주 섭취하지 않는 군에서 32.4%로서, 매일 섭취하는 경우에 상악 유전치 우식증과의 유의한 연관성이 있었다(P<0.05). 연령, 모유 수유 또는 인공 수유, 칫솔질 시작 시기, 1일 칫솔질 횟수에서는 상악 유전치 우식증과 유의한 연관성이 나타나지 않았다(P>0.05). The purpose of study was to investigate the etiologic factors of maxillary primary anterior caries. The subjects of study were 401 preschool children, 214 boys and 187 girls, from 36 to 71 months old of randomly selected seven nurseries in Iksan city. The prevalence of maxillary primary anterior teeth was cross-analyzed with gender, age, breast feeding or bottle feeding, length of feeding, sweet snack intake frequency, beginning of tooth-brushing, and toothbrushing frequency per day. The prevalence was 43.0% in boys and 26.7% in girls, and there was significant association between the prevalence and gender in cross analysis(P<0.01). The prevalences of the shorter than 2 years of feeding group, the from 2 to 3 years group, and the longer than 3 years group were 31.0%, 43.2%, and 63,2%, respectively, and there was significant association between the prevalence and the length of feeding (P<0.01). Daily intake of sweet snacks had a significant association with the prevalence(P<0.05) There was no significant association between the prevalence and the variables of age, breast feeding or bottle feeding, beginning of toothbrushing, and toothbrushing frequency per day(P>0.05).

      • KCI등재

        진단 기준에 따른 취학전 어린이의 중증 유아기 우식증 유병률 비교

        임경욱,이광희,라지영,이동진,안소연,김지영,송지현,김윤희 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.4

        연구목적은 중증 유아기 우식증에 대한 두 개의 정의를 진단 기준으로 하였을 때 각 기준에 따른 유병률이 일치하는 정도를알기 위함이었다. 연구대상은 익산시 어린이집 중에서 무작위로 추출한 7개 어린이집의 36개월 이상 71개월 이하 어린이401명 이었다. 치경과 탐침을 사용한 구강검사를 통하여 치아별 우식경험유치면 (dmfs)의 수를 조사하였으며 . 중증 유아기 우식증의 진단 기준은 (1) 상악 전치에 1개 이상의, 와동이 형성된 우식,상실(우식증에 의한), 충전 평활면이 있거나 (2) 우식,상실,충전 치면의 수가 3세는 4개 이상.4세는 5개 이상.5세는 6개 이상인 경우로 하였다. 상악 전치부 우식증에 의한 우식유병률과 우식경험유치면수(dmfs)에 의한 우식유병률은 3세에서 각각 26.7%. 28.9%, 4세에서 각각 32.4%, 30.4%, 5세에서 각각 39.4%, 41.3%, 전체에서 각각 35.4%, 35.9%으로서. 연령별로는 약간의 차이가 있었으나 전체에서는 차이가0.5%로서 거의 일치하였다. 따라서 중증 유아기 우식증의 진단은 두 가지 기준 중에서 어느 하나를 사용하더라도 비슷한 결과가 나을 것이라는 것을 확인할 수 있었다. The purpose of study was to compare the prevalences of severe early childhood cahes(S-ECC) using two different diagnostic criteria. The subjects of this study included 401 preschool children from 36 to 71 months of the randomly selected seven nurseries in Iksan city. Severe early childhood caries was defined as (1) 1 or more cavitated, missing (due to caries), or filled smooth surfaces in primary maxillary anterior teeth or (2) a decayed, missing, or filled score of ≥4 (age 3), ≥5 (age 4), or ≥6 (age 5) surfaces. The prevalence determined by maxillary anterior caries and the prevalence determined by dmfs were 26.7%, 28.9% in 3 years, 32.4%, 30.4% in 4years. 39.4%, 41.3% in 5 years, and 35.4%, 35.9% in all, respectively. The results suggest that the two diag-nostic criteria of the severe early childhood caries yield almost the same results.

      • KCI등재

        Streptozotocin 유도 당뇨쥐에서 C3G 및 D3G 안토시안이 풍부한 검정콩 CJ-3호 종피 추출물의 혈중지질 개선효과

        박소영(Park, So Young),박수정(Pak, Sujeong),강송주(Kang, Song Joo),김나영(Kim, Na Young),김다샘(Kim, Da Saem),김민진(Kim, Min Jin),김선아(Kim, Seon Ah),김지영(Kim, Ji Young),박소연(Park, So Yeon),박소현(Park, So Hyun),윤초롱(Youn, Ch 한국영양학회 2015 Journal of Nutrition and Health Vol.48 No.4

        기존 연구에서 주로 사용하는 기타 재래종 검정콩 종피추출물 (콩단백질 혹은 총 안토시안)의 효과를 연구하는 경우와 달리, 본 연구에서는 재래종 서리태보다 C3G와 D3G 안토시안이 2배 이상 풍부한 검정콩 CJ-3호 종피추출물을 이용하였다. STZ로 유도된 당뇨쥐에 4주간 검정콩 CJ-3호 종피추출물을 처치한 결과 비록 체중감소, 혈당강하, 인슐린저항성 완화 등의 효과는 미비하지만 근육량이 유의적으로 증가하였는데 이는 일반적으로 항비만 식이요법에 따라 나타나는 근육소모를 보완하는 중요한 효과이다. STZ유도 당뇨 쥐에서 억제된 글리코겐이용률이 검정콩 CJ-3호 종피추출물에 의하여 증가한 것은 포도당이 에너지원으로 사용되면서 지방조직의 지질이용률을 억제하여 혈중 TG를 개선시켰고 간에서 HMG-CoA reductase 활성을 조절함으로써 혈청 TC를 낮추는데 기여하였다. 4주간의 투여기간을 연장한다면 향후 당뇨에서 발생하는 인슐린저항성 및 당화적 산화성억제에 따른 지질의 과산화물의 생성을 억제할 수 있는 가능성도 기대할 수 있겠다. 또한 검정콩 CJ-3호는 병 저항성이 높고 종실특성이 우수한 녹자엽 검정콩으로 생산성이 높아서 기능성에 대한 반복실험을 확인한다면 기능성식품시장의 산업화도 가능하다. 따라서 C3G와 D3G 안토시안이 풍부한 기능성 식품의 경우 당뇨, 비만 및 암 등 난치병질환에서 나타나는 혈중지질 개선을 위한 임상적 효과 또한 기대해 볼 수 있겠다. Purpose: The purpose of this study was to examine the effect of black soybean (CJ-3) testa extracts on lipid profiles in streptozotocin (STZ)-induced diabetic rats. Methods: One control group and four STZ-induced diabetic groups with different doses of black soybean (CJ-3) testa extracts treatment [0 mg/kg (diabetic control, EX), 250 mg/kg (EX-250), 500 mg/kg (EX-500), 1,000 mg/kg (EX-1000)] were orally administered for 4 weeks. Results: All CJ-3 treatment groups had remarkably lower serum triglyceride (TG) levels than that of EX group (p < 0.05) whereas hepatic TG contents did not show any differences. Results from serum total cholesterol (TC) concentrations of EX-250 and EX-1000 groups were decreased compared to EX group (p < 0.05). Furthermore, protein levels of 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase from the liver decreased in all treatment groups (p < 0.05). However, significant differences were not observed in serum glucose and insulin, and glucose transporter 4 (GLUT-4) protein expression in skeletal muscle tissue. Conclusion: These results suggest that black soybean testa extracts could be useful for improvement of hyperlipidemia and hypercholesteremia in diabetes.

      • KCI등재

        다량의 태아-모체간 수혈로 인한 중증 신생아 빈혈 2예

        송은송 ( Eun Song Song ),김기환 ( Ki Hwan Kim ),김소연 ( So Youn Kim ),박천학 ( Chun Hak Park ),최영륜 ( Young Youn Choi ) 대한주산의학회 2004 Perinatology Vol.15 No.2

        Feto-maternal hemorrhage, the presence of fetal red blood cells in the maternal circulation, occurs in up to 75% of pregnancies. But its volume is usually very small. Feto-maternal hemorrhage of more than 30 ml of whole blood is relatively rare. The key features that lead to early diagnosis are the maternal history, fetal monitoring, the clinical and laboratory findings of anemia and a negative Coombs` test. Diagnosis is confirmed by Kleihauer-Betke test. Perinatal problems include fetal distress, neonatal anemia, hypovolemic shock, and death. The fetal outcome depends on the amount and rate of bleeding. The initial hemoglobin level was a better predictor than the volume of bleeding. We present two cases of severe neonatal anemia associated with massive feto-maternal hemorrhage, which was confirmed by Kleihauer-Betke test.

      • KCI등재후보

        Comparison of the Korean Activity Status Index with cardiopulmonary exercise test in patients with acute myocardial infarction

        Youn Ji Kim,Jun Hwan Choi,Bo Ryun Kim,So Young Lee,Hyun Jung Lee,Song-Yi Kim,Jae-Geun Lee 제주대학교 의과학연구소 2022 The Journal of Medicine and Life Science Vol.19 No.2

        This study aimed to compare the Korean Activity Status Index (KASI) with the cardiopulmonary exercise test (CPET) among patients with acute myocardial infarction. A total of 2,268 patients (85.4% male; mean age, 59.3±10.2 years; range, 23-90 years) diagnosed with acute myocardial infarction were enrolled in the Regional Center Myocardial Infarction Registry between July 2016 and June 2019. The KASI is a tool used to measure functional capacity by asking patients about their ability to perform specific activities and then scoring their responses. In contrast, CPET is the gold standard for assessing the objective functional capacity in patients undergoing cardiac rehabilitation. Peak oxygen uptake (VO2peak) was used to analyze the correlation. Patients who completed two consecutive KASI and CPET evaluations during their first (KASI_1, VO2peak_1) and second visits (KASI_2, VO2peak_2) for cardiac rehabilitation were included in the study. The mean KASI_1 and KASI_2 scores were 43.3±14.3 and 49.8±13.9, respectively, and the mean VO2peak_1 and VO2peak_2 scores were 25.9±8.0 and 28.5±8.3, respectively. Both the KASI scores were significantly correlated with the measured VO2peak during each visit, with correlation coefficients of 0.385 (P<0.001) and 0.346 (P<0.001), respectively. Moreover, the KASI score and VO2peak had a linear relationship (VO2peak_1=0.22×KASI_1+16.5, P<0.001; VO2peak_2=0.21×KASI_2+18.2, P<0.001). This study revealed that the KASI is a valid measure for the follow-up evaluation of the functional capacity of patients. These findings suggest that VO2peak can be predicted using the KASI score in patients who do not undergo CPET.

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