강박장애와 공황장애 환자의 삶의 질

손상준,김세주,김찬형 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.5

Objectives : Aim of this study was to compare quality of life (QOL) in obsessive compulsive disorder (OCD), panic disorder (PD) and healthy controls. Additionally, relationship between clinical factors in patients and their QOL were explored. Methods : 49 patients with OCD, 109 patients with PD and 54 healthy controls were recruited. Total scores and scores of each domain of WHO Quality of Life scale (WHOQOL) were compared in the three groups. Correlation analysis and regression analysis were performed to examine the relationship between QOL and the clinical characteristics in the patient group. Results : Total scores and scores of all domains except environmental domain of WHOQOL in patient group were decreased compared to those in healthy control. Scores of social and psychological domains in the OCD group were lower than those in the PD group. The severity of agoraphobia and depression were factors affecting the QOL in the PD group. For the OCD group, comorbid depression was related to social and psychological domain of WHOQOL. Conclusion : QOL in patients with OCD and PD was poorer than that of healthy controls. Social relationships and psychological functioning may be poorer in patients with OCD than patients with PD. The severity of depression and agoraphobia predicted QOL in patients with PD. Comorbid depression in OCD might be a predictor of poor QOL.

Two Stage 발효에 의한 고산도 식초 생산

이영철,이금용,김형찬,박기범,유익제,안평욱,최춘언,손세형 한국산업미생물학회 1992 한국미생물·생명공학회지 Vol.20 No.6

산업적으로 산도 17.0% 이상의 고산도 식초를 생산하기 위하여 반연속식인 1st stage와 유가식인 2nd stage로 구성된 two stage 초산 발효를 온도 30 ℃, 교반속도 600 rpm, 통기량 0.1 vvm에서 실시하였다. 1st stage에서 초기 에탄올 농도를 50.0 g/ℓ, 잔류 에탄올 농도를 5.0 g/ℓ로 정하여 반연속적으로 초산발효를 하고, 2nd stage 에서 발효시간의 경과에 따라 에탄올을 유가식으로 첨가하여 초산발효액내의 에탄올 농도를 5.0 g/ℓ에서 10.0 g/ℓ로 유지했을 때 산도가 17.6%인 고산도 식초를 생산할 수 있었으며, 또한 이 ??의 최대 초산 생산성은 3.3 g/ℓ·hr였다. The production of vinegar containing 16.0 ∼18.0% of acetic acid was examined in two stage fermentation consisting of semi-continuous and fed-batch type. The optimum conditions were obtained when the fermentation was carried out at agitation of 600 rpm, aeration of 0.1 vvm and temperature of 30℃. The initial and residual ethanol concentration in 1st stage were 50.0 g/ℓ and 5.0 g/ℓ, respectively, and the ethanol concentration in 2nd stage was maintained from 5.0 to 10.0 g/ℓ. The maximum productivity was 3.3 g/ℓ-hr and the acidity was 17.6% after the two days of acetic acid fermentation.

A case of McKusick-Kaufman syndrome

Son, Se-Hyung,Kim, Yoon-Joo,Kim, Eun-Sun,Kim, Ee-Kyung,Kim, Han-Suk,Kim, Beyong-Il,Choi, Jung-Hwan The Korean Pediatric Society 2011 Clinical and Experimental Pediatrics (CEP) Vol.54 No.5

McKusick-Kaufman syndrome (MKS) is an autosomal recessive multiple malformation syndrome characterized by hydrometrocolpos (HMC) and postaxial polydactyly (PAP). We report a case of a female child with MKS who was transferred to the neonatal intensive care unit of Seoul National University Children's Hospital on her 15th day of life for further evaluation and management of an abdominal cystic mass. She underwent abdominal sonography, magnetic resonance imaging, genitography and cystoscopy which confirmed HMC with a transverse vaginal septum. X-rays of the hand and foot showed bony fusion of the left third and fourth metacarpal bones, right fourth dysplastic metacarpal bone and phalanx, right PAP and hypoplastic left foot with left fourth and fifth dysplastic metatarsal bones. In addition, she had soft palate cleft, mild hydronephroses of both kidneys, hypoplastic right kidney with ectopic location and mild rotation, uterine didelphys with transverse vaginal septum and low-type imperforated anus. She was temporarily treated with ultrasound-guided transurethral aspiration of the HMC. Our patient with HMC and PAP was diagnosed with MKS because she has two typical abnormality of MKS and she has no definite complications of retinal disease, learning disability, obesity and renal failure that develop in Bardet-Biedl syndrome, but not in MKS until 33 months of age. Here, we describe a case of a Korean patient with MKS.

임상 ; 식이부전으로 소장 조영술을 시행 받은 조산아 46례의 임상적 고찰

손세형 ( Se Hyung Son ),김윤주 ( Yoon Joo Kim ),이주영 ( Ju Young Lee ),이은희 ( Eun Hee Lee ),손진아 ( Jin A Sohn ),김은선 ( Eun Sun Kim ),김이경 ( Ee Kyung Kim ),김한석 ( Han Suk Kim ),김병일 ( Beyong Il Kim ),최중환 ( Jung Hwan 대한주산의학회 2010 Perinatology Vol.21 No.2

목적: 조산아에서 식이 진행이 잘 되지 않는 경우에 소장조영술 검사를 시행해 볼 수 있다. 그러나 현재까지 조산아에서 소장조영술의 안정성과 유효성 평가가 확립되어 있지 않다. 본 연구를 통해 소장조영술의 최근 경험을 조사하여 조산아에서 식이진행이 되지 않을 경우에 소장조영술 검사에 대해 기초자료를 제시하고자 한다. 방법: 2005년 1월부터 2008년 10월까지 서울대학교 병원 어린이병원 신생아 중환자실에 입원하여 소장조영술을 시행한 46명의 조산아들을 연구대상으로 하여 의무기록을 후향적으로 분석하였다. 결과: 평균 재태기간과 평균출생체중은 각각 30(+1)±3(+5)주(24-36주), 1,435±623g (460-2,810g)이었다. 소장조영술을 시행한 평균 수태후 연령은 37(+2)±4(+2)주(중간값 36(+2)주, 27(+2)-45(+4)주)였고 이는 생후 46.8±27.3일(5-126일)에 시행되었다. 소장조영술 검사를 시행한 결과에서 기계적 장폐색이 없었던 경우는 29명(63%)이었고 이들 중 22명(47.8%)은 위장관 이행 시간이 연장되어 있었다. 그러나 이들은 결국 완전 장관 영양에 도달하였고 도달하는 데 걸린 시간은 평균 11.2일이었다(중간값 6일). 소장조영술을 시행한 신생아들을 출생체중에 따라 1.5kg 미만 군과 1.5kg 이상 군으로 분류하였을 때 각각 27명, 19명이었다. 1.5 kg 이상 군에서는 검사를 더 일찍 시행하였다(P=0.027). 1.5kg 미만 군에서는 27명 중 15명(55.6%)에서 인공호흡기 치료를 받거나 인큐베이터 내에서 치료 중으로 침상 옆에서 검사를 시행하였다. 1.5kg 미만 군에서는 신생아괴사성장염, 태변연관 장폐색 및 위장관 수술 과거력이 1.5kg 이상 군보다 유의하게 많았다(P=0.044). 소장조영술 시행 시 사용한 조영제는 바륨, 텔레브릭스, 가스트로그라핀이었고 조영제 사용 후 관련된 합병증으로 구토 및 조영제 정체가 있었으나 대부분 호전되었고 흡인이나 패혈증 등의 부작용은 없었다. 결론: 식이 부전이 있는 조산아에서 적극적인 소장조영술 검사는 식이부전의 원인을 밝히고 이를 해결하는 데에 도움이 되므로 식이를 진행하는 데에 도움이 될 것이다. Objective: Small bowel series (SBS) may be a useful test in identifying the causes of feeding intolerance in preterm infants. Unfortunately, little is known about the safety and effectiveness of SBS in preterm infants. By scrutinizing our recent experiences in performing SBS in preterm infants, we aim to provide basic data concerning the use of SBS in preterm infants with feeding intolerance. Methods: Between January 2005 and October 2008, SBS was done in 46 preterm infants with feeding intolerance, who were admitted to the neonatal intensive care unit (NICU) of Seoul national university children`s hospital. We conducted a retrospective analysis of these preterm infants. Results: The average gestational age and birth weight of the 46 infants were, 30(+1)±3(+5) weeks, 1,435±623 g, respectively. The mean postconceptional age when SBS was done, was 37(+2)±4(+2) weeks, 46.8±27.3days. SBS proved that 29 infants did not have mechanical obstructions and 22 of these infants had delayed bowel transit time. Eventually, 35 infants attained full feeding except those who underwent operation. SBS was done at their bedside in 15 out of 27 infants in the group less than 1.5kg. History of NEC, meconium related ileus, and gastrointestinal operation were more frequent in the group less than 1.5kg. The adverse effects of SBS in preterm infants included vomiting, delayed transit of the contrast media, all of which resolved in the end and there were no reports of aspiration or sepsis. Conclusion: Actively performing SBS test in preterm infants with feeding intolerance will promote feeding advancement by discovering the cause of feeding intolerance and subsequent management of the specific problem.

A study on the evolutionary process of late-type stars through maser observations

Se-Hyung Cho,Jaeheon Kim,Seong-Min Son,Bianca Els,Hyun Baek,Kyung-Won Suh 한국천문학회 2023 天文學會報 Vol.48 No.1

Design of new quadruped robot with SMA actuators for dynamic walking

Hyung-Min Son,Jun-Bum Gu,Se-Hoon Park,Yun-Jung Lee,Tae-Hyun Nam 제어로봇시스템학회 2006 제어로봇시스템학회 국제학술대회 논문집 Vol.2006 No.10

A study on the evolutionary process of late-type stars through maser observations II

Se-Hyung Cho,Jaeheon Kim,Seong-Min Son,Hyun Baek,Dong-Hwan Yoon,Kyung-Won Suh 한국천문학회 2023 天文學會報 Vol.48 No.2

Case Reports : Management of Complex Regional Pain Syndrome Type 1 With Total Spinal Block

( Se Jin Ok ),( Jong Yeun Yang ),( Ju Hyung Son ),( Won Ju Jeong ),( Yoon Sook Lee ),( Woon Young Kim ),( Young Cheol Park ) 대한통증학회 2010 The Korean Journal of Pain Vol.23 No.1

Second Law Optimization of Water-to-Water Heat Pump System

Kyu-Hyung Kim,Joung-Son Woo,Se- Kyoun Lee 대한기계학회 2003 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.17 No.1

This paper presents a thermodynamic analysis of heat pump system using water as a heat source and heat sink. The primary object in this study is the optimization of exergetic efficiency. Two different systems, 2-stream and l-stream system, are analyzed in detail. Mass flow ratio (the ratio of mass flow rate of water through evaporator to that through condenser) is identified as the most important parameter to be optimized. It is shown that there exists an optimum mass<br/> flow ratio to maximize exergetic efficiency. The variation of optimum exergetic efficiency of<br/> 2-stream system is quite small and the value lies between 0.2~0.23 for the range of investigation in this study. However, far better performance can be obtained from l-stream system. This means considerable irreversibilities are generated through condenser of the 2-stream system. The effects of adiabatic efficiency of compressor-motor unit on the overall system performance are also examined in the analysis.<br/>

Management of Complex Regional Pain Syndrome Type 1 With Total Spinal Block

Ok, Se-Jin,Yang, Jong-Yeun,Son, Ju-Hyung,Jeong, Won-Ju,Lee, Yoon-Sook,Kim, Woon-Young,Park, Young-Cheol The Korean Pain Society 2010 The Korean Journal of Pain Vol.23 No.1

Complex regional pain syndrome (CRPS) is a painful and disabling disorder that can affect one or more extremities. Unfortunately, the knowledge concerning its natural history and mechanism is very limited and many current rationales in treatment of CRPS are mainly dependent on efficacy originated in other common conditions of neuropathic pain. Therefore, in this study, we present a case using a total spinal block (TSB) for the refractory pain management of a 16-year-old male CRPS patient, who suffered from constant stabbing and squeezing pain, with severe touch allodynia in the left upper extremity following an operation of chondroblastoma. After the TSB, the patient’s continuous and spontaneous pain became mild and the allodynia disappeared and maintained decreased for 1 month.