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서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
MgCl₂溶液內에서 STS 304 HP Stainless Steel 熔接部의 破壞擧動에 對한 硏究
金永奭,丁太權,朴昌彦,洪錫柱,梁仁榮,金基玉,朴煥奎,李茂錫,曺圭宰,鄭在康 조선대학교 생산기술연구소 1983 生産技術硏究 Vol.1983 No.-
This paper is based on an experiment analysing the stress corrosion cracking behaviour of welding specimens compared to that of non-welding specimens of STS 304 HP stainless steel in corrosion solution. As a corrosion condition, stainless steel has been known to be the most fragile in a solution of 42% MgCl₂heated to the boiling point, therefore the experiment was carried out in this condition. The experiment was carried out with argon gas TIG welding specimens and non-welding ones made of stainless steel plates, thickness 2mm, by tensile force. At this time, the tensile force was taken to be the value of the yield strength of the tensile test specimens divided by the safety factor of 3.0 to 3.5, 4.0, 4.5, and 5.0. In this paper, the relations between Time of Initial Crack, Time of Failure, Time of Final Fracture and Crack Propagation Length were investigated and then plotted. Furthermore, the relations between Stress Intensity Factor K proposed by Irwin and the Time of Initial Crack, the Time of Failure, the Time of Final Fracture were calculated and plotted. At the last, all the relations plotted were expressed to normal equations by computer, and the equations were used to analyse the data obtained in the experiment. The conclusions obtained in this study are as follows: 1. Welding materials, compared with non-welding ones, as the Time of Initial Crack, the Time of Failure, and the Time of Final Fracture were generally very fast, appeared to be a phenomenon of unstable brittleness fracture. 2. Non-welding materials, compared with welding ones, as the safety factor was larger or the working stress was smaller, appeared to be a phenomenon that the longer had had greater durability. Therefor, welding materials must be considered enough to be used in heate affected and stress corrosion atmosphere. 3. The normal equations of the Time of Initial Crack and the variation rate to the same Stress Intensity Factor K are as follows: (A) Non-welding T =259702.4-5451.2 K+28.386 K² T = -5451.2+28.386 K (B) Welding T= -332.693+28.043 K-0.211 K² T' =28.043-0.211 K here, T; Time of Initial Crack, T'; Variation Rate of Time of Initial Crack to Stress Intensity Factor K, K ; Stress Intensity Factor.
무선 인지 환경을 위한 효율적인 동적 스펙트럼 활당 기법
김주석,김경석,박우구,김진업 충북대학교 컴퓨터정보통신 연구소 2006 컴퓨터정보통신연구 Vol.14 No.2
무선 기술이 발달함에 따라 주파수 자원의 부족문제가 점점 심해지고 있고, 이를 해결하기 위해 주파수 공유기술로 무선인지 (cognitive radio: CR)가 부각되고 있다. 본 논문에서는 CR 기반의 IEEE 802.22 WRAN 환경에서 동적 스펙트럼 할당 (Dynamic Spectrum Allocation: DSA) 기법을 연구하였다. 주파수를 좀 더 효율적으로 공유하기 위해 Variable bandwidth, 이동성, 셀 간 간섭을 적용한 DSA 기법을 제시하고 시뮬레이션 결과들을 통해 이를 검증하였다. As a wireless technique advances, the shortage problem of frequency resource has been gradually serious. Cognitive radio(CR) have been noticed to solve this problem by using frequency sharing methods. We investigate dynamic spectrum allocation(DSA) method in IEEE 802.22 WRAN environment of CR foundation in this paper. To share frequency more efficiently, we propose some DSA techniques for variable bandwidth, mobility, intercell interference and verify these through the result of the simulations.
김주필(Joo-Pil Kim),예용택(Yong-Taek Ye),최한석(Han-Seok Choi),장지현(Jee-Hyeon Jang):예성훈(Seong-Hun Ye),김태우(Tae-Woo Kim),김대희(Dae-Hee Kim),지승환(Seung-Hwan Ji),이형민(Hyung-Min Lee),이형진(Hyung-Jin Lee) 한국거미연구소 2016 한국거미 Vol.32 No.2
2016년 8월 3일부터 5일까지 제주특별자치도 서귀포시 대정읍 마라도 일대를 한국거미연구회 하계 합동채집회에 김주필, 예용택, 최한석, 장지현, 예성훈, 김태우, 김대희, 지승환, 이형민, 이형진, 신정애, 허양미, 이영경, 최라미, 이윤정 등이 채집조사한 결과 15과, 39속, 45종의 거미류가 조사연구되어 이에 보고하는 바이다. The authors investigated the spiders of the Mara Island in Jeju Island. In the present paper 45 species of 39 genera belong to 15 families were identified. These specimens are deposited at the Joo-Pil Spider Museum, Namyangju-Si, Kyunggi-Do.
김정주,이석주,임호준 경희대학교 체육과학연구소 1995 體育學論文集 Vol.23 No.-
It was researched by a written inquiny way about sports injury with 208 professional baseball players of 8 teams from March, 1995 to October 1995 and reached such conclusion as below. 1.About the question of the situation they first got injured since entered the teams, "on practice" was answered by 112 players(53.84%). 2.About the question of the repetition frequency of the injured part, "1-3 times" was answered most by 139 players(66.83%). 3.About the question that have you been participated to play in game or practice with unrecovered injury, "yes" was answered by 180 players(86.53%) 4.About the question of the reasons of injury occurrence, "my carelessness" was answered by 92 players(44.23%). 5.About the question of the warming up time before game or practice, "30 minutes was answered by 87 players(41.83%). 6.About the question of the private warming up time, "5-10 minutes" was answered by 85 players(40.87%). 7.About the question of the way to prevent injury, "strict warming up" and "reinforcement of physical strength" were answered by 82 players each(39.42%). 8.About the question trial after injured did you satisfy the curing of doctor and its period of time, "unsatisfaction" was answered by 145 players(69.71%). 9.About the question of the seasons they got injured, "Spring" was answered by 9 players(33.117%). 10.About the question of the injured gnarl on play on pitchers, "the hips part" was answered most by 68 placers(77.27 %). 11.About the question of the injured part on play of catchers, among 70 cases totally occurred, "the shoulder part" was answered by 12 players(60.00%). 12.Aboul the question of the injured part on play of infielders, among 220 cases totally occurred, "the shoulder part" and "the foot joint part" were answered most by 27 players each(41.54%). 13.About the question of the injured part on play of outfielders, among 137 cases totally occurred, "the head part", "the abdomen part" and "the back part" by 1 each(2.85%). 14.About the question of the joint injury, For pitchers, 161 cases totally occurred, "the sprain" was answered most by 59 players(67.04%), For catchers, 32 cases totally occurred, "the sprain" most by 9 players(45.00%) "the dislocation", and "the changes of hyperplastic joint" by 1 each(5.00%).5(7.69%). 15.About the question of the skin injury in each defence position, For pitchers, 78 cases totally occurred, "the abrasion" was answered by 25 players(28.40%). For catchers, 23 cases, "the abrasion" by 10 players(50.00%). 16.Aboul the question of the muscle and tendon injury, "the muscle contusion" was answered most by the players of each position. For outfielders, 56 cases, "the muscle contusion" by 22 players(62.85%). 17.Aboute the question of the bone injury, For pitchers, 89 cases totally occurred, "the bone contusion was answered by 34 players(38.64%). 18.About the question of the brain injury, For pitchers, 22 cases totally occurred, "the contuslo cerebri" was answered by 11 placers(12.50%). 19.About the question of the nerve injury. For pitchers, 9 cases totally occurred, "the nerve contusion" was answered by 6 players(6.81%).
Multiple myeloma 환자에서 Bortezomib치료 후 발생한 마비성 장폐색증 1례
김준영,이원식,손창학,박성길,진한영,박석주,조영완,정은욱,강명주,박정하,주영돈 인제대학교 2006 仁濟醫學 Vol.27 No.-
Bortezomib is the first clinically available proteasome inhibitor that is clinically effective in the treatment of multiple myeloma. A proteasome inhibitor acts through multiple mechanisms to arrest tumor growth, tumor spread, and angiogenesis. The main adverse effects of bortezomib are gastrointestinal symptoms, cytopenia, fatigue, and peripheral neuropathy. To date, severe paralytic ileus has not been reported as a toxic effect of bortezomib treatment in multiple myeloma. Bortezomib is a novel agent that has only been used clinically for 30 months, so a need exists to further evaluate its toxicity. We report a case of grade Ⅲ (NCI CTCAE v3.0) or grade Ⅳ(SWOG toxicity criteria) paralytic ileus in a 65-year-old man with relapsed multiple myeloma who underwent one cycle of single-agent bortezomib treatment scheduled in a 21-day cycle (1.3 mg/㎥ as a single i.v. bolus on days 1, 4, 8, and 11).
수온에 따른 Norfloxacin의 잉어(Cyprinus carpio)와 뱀장어(Anguilla japonica)체내에서 약물동태학적 특성
김진우,정승희,이주석,최동림,조미라 한국어병학회 2002 한국어병학회지 Vol.15 No.2
양식어류의 세균성 질병 치료약제로서 사용량이 증가하고 있는 NFX의 정량분석 방법을 확립하고, 사육수온과 관련된 NFX의 어체내에서 흡수, 분포, 배설 등 NFX의 합목적적 사용 방법 설정에 필요한 약물동태학적 요인을 조사하였다. 수온에 따른 NFX의 어체 내에서의 혈중최대 농도는 뱀장어에서는 유의적인 차이는 없었으나 잉어에서는 혈중최대농도가 23℃에서 유의적으로 높게 (p〈0.05) 나타났을 뿐만 아니라 NFX의 흡수 및 배설속도정수, 최대혈중농도 도달시간 등 어종별, 수온별 약물동태학적 요인에 차이가 있었다. 이러한 결과로 NFX의 효과적인 사용방법과 휴약기간 설정을 위하여 어류의 사육환경과 관련된 임상 약물동력학적 특성을 충분히 고려하여 결정되어야 할 것으로 판단된다. Effects of Temperature on the pharmacokinetics of norfloxacin(NFX) were studied in the cultured carp, Cyprinus caripo, and cel, Angulla japonica, using high performance liquid chromatography(HPLC) originally developed for quinolone determination in livestocks. Pharmacokinetics of NFX was apparently affected by amibent water temperature. In a two-compartment model for carp after oral dosage of 20㎎/㎏, K01 at 13℃ and 23℃ were 2.60 and 5.20/hr, respectively. In carp the K_(w), T_(max) and C_(max) for carp at 13℃ were 13.30/hr, 17.44 ug/ml and 7.00 ug/ml, respectively. The corresponding values at 23℃ were 3.93/hr, 15.40㎍/㎖ and 9.44 ㎍/㎖, respectively. The AUC and T_(1/2) were 355.66 ㎍:hr/㎖ and 12.70 hr at 13℃ and 417.24 ㎍:hr/㎖ and 13.86 hrs at 23℃, respectively, Similar trends were revealed in the NFX pharmacokinetics of cel kept under the two water temperature regimes after oral NFX dosage of 20 mg/kg. These pharmacokinetical results have some implication in the optimal usage of recently introduced antibacterials in farmed fish, which were originally adapted for poultry and mammalian species.