제 2형 당뇨병 환자에서 대사증후군의 유병률 및 관련요인의 특징

박철진,박거운,박일구,신지혜,김진화,배학연,김상용 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.3

Background: People with insulin resistance has a higher risk of developing cardiovascular disease. This leads to the importance in diagnosing metabolic syndrome. The incidence of metabolic syndrome has increased significantly in korea because of an increased population of obese people and also the incidence of DM. There have been many studies done on the incidence of metabolic syndrome in the general population. Therefore, the authors have designed this study to identify the incidence of metabolic syndrome in patients with type 2 DM and also the associated characteristics in that population. Methods: The study included 169 adults over the age of 20 (84 males and 85 females) admitted to the endocrinology department of Chosun University between Jan, 1st 2005 and May, 31st 2006. Out of the people diagnosed with type 2 DM people were excluded when any of the physical measurements (height, weight, blood pressure, abdominal circumference) and blood measurements (TG, HDL-cholesterol, fasting blood sugar) were insufficient and when the patient was taking any drugs other than anti-hy-pertensive agents and oral anti-diabetic agents. Obesity and the other risk factors were defined by the Asian-Pacific guideline and 2001 ATP III of NCEP, respectively. Result: The each prevalence according to the metabolic syndrome criteria of the type 2 DM patients showed low HDL cholesterolemia with the highest incidence of 57.4% followed by hypertng1yceridemia(52.0%), obesity(40.9%) and hypertension(33.0%). The each incidence of diagnostic criteria in metabolic syndrome according to sex was different, In males, hypertriglyceridemia was the highest with the incidence of 57.7% followed by low HDL-cho1estero1emia(49.5%), obesity(40.9%) and hypertension (30.0%). In women, the incidence were low HDL-cho1estero1emia(64.8%), hyperthg1yceridemia(47.6%), obesity(45.0%) and hypertension(36.0%), in a descending order. The analysis between the diagnosis of metabolic syndrome in type 2 DM patients and the criteria showed that hyperthglyceridemia (correlative value 0.575) had the highest correlation followed by low HDL-cholesterolemia (correlative value 0.446), obesity (correlative value 0.350) and hypertension (correlative value 0.410). All the correlations were statistically significant with a p-value less than 0.01. Conclusions: Type 2 DM is a important factor of metabolic syndrome based on insulin resistance. The control of blood glucose with prevention and early diagnosis of the other factors related to metabolic syndrome in type 2 DM is important for preventing cardiovascular complications.

NSIP와 BOOP의 고해상전산화단층촬영 소견과 비교

백상현,박재성,차장규,홍현숙,김대호,박성진,조준희,이혜경,최진수 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2

Purpose: BOOP and NSIP also share similar clinical features such as subacute flu-like illness, the finding of bronchoalveolar lavage, the result of pulmonary function test and more favourable outcome than usual interstitial pneumonia(UIP). The author try to compare the HRCT findings of NSIP with BOOP by pattern and distribution of diseases. Materials and Methods: HRCT findings of histopathologically proven NSIP(Group Ⅰ; 6, Group Ⅱ; 7, Group Ⅲ; 2) in 15 patients(5 male, 10 female, age range, 39-69 years; mean age, 53 years), BOOP in 15 patients(6 male, 9 female, age range, 26-76 years; mean age, 52 years) were reviewed retrospectively. Results: The common pattern of the two diseases was admixed consolidation, ground glass attenuation & reticular densities with/without architectural distortion(NSIP; 53.3%, BOOP; 46.7%). The main component of the pattern wan predominantly consolidation(NSIP; 46.7%, BOOP; 73.3%) and ground glass attenuation(NSIP; 40.0%, BOOP;20.0%). Architectural distotion was more provinent finding with NSIP(mild ; 3, moderate ; 4, severe; 2) compared with BOOP(mild; 7, moderate; 2, severe; 0). The predominant overall distribution was lower lung, peribronchovascular & peripheral lung field in both of the two entities(NSIP;73.3%, BOOP; 73.3%). Peribronchovascular involvement was more common with NSIP(100%) than BOOP(80%), whereas peripheral involvement was more common with BOOP(93.3%) than NSIP(80%). Conclusion: The HRCT findings of NSIP and BOOP were similar in pattern and distribution. But NIP manifested more frequently ground-glass attenuation, whereas BOOP showed more frequently consolidation. Architectural distortion was more severe with NSIP than BOOP. NSIP invoved more frequently peribronchovascular space and BOOP were more common in peripheral lung field.

I. 택지개발지구내 주변 환경에 따른 단독주택지 경계부 건축물 용도변화에 관한 연구 - 대구광역시를 중심으로 -

이숙준,박해주,이진욱,하재명,Lee, Sook-Joon,Park, Hae-Joo,Lee, Jin-Wook,Ha, Jae-Myung 한국주거학회 2006 한국주거학회 논문집 Vol.17 No.6

The purpose of this study is to investigate tendencies on land use in the housing site development district by grasping the characteristics of changes of building use at the borders of single-detached housing area for planning single-detached housing area in the future. It is divided the borders of detached housing areas into three types, educational facility, parks and green spaces, and apartment complex, and then analyzed the characteristics of each location after a field study. It is summarized as follows. First, there were stationery and flour-based meal stores in adjacent borders near educational facilities, suitable for students' interest and motion patterns, and it is required to consider about frequent children's action in the street. Second, there are many facilities for park users and residents, such as educational institutes and restaurants in adjacent to borders near parks. In borders neighboring buffer green belt areas, warehouses and vacant sites were mainly distributed. And the revitalization of streets was lower than others, because a road was used as a parking space. Third, there were realty dealers, food stores, and laundries which provide the dwellers with service in adjacent borders near multi-family housing.

Rogers의 인간중심적 상담기법을 적용한 청소년 테니스 선수 상담사례연구

박혜주,김진구,정상택 한국스포츠심리학회 2003 한국스포츠심리학회지 Vol.14 No.4

스포츠 상담이란 선수의 문제해결을 목적으로 상담서비스를 제공하는 행위를 말한다. 경쟁적인 스포츠에 참가하는 선수들은 성장과 발달의 과정에서 여러 가지 많은 문제들에 직면하게 될 때 상담자로서의 스포츠 심리학자를 절실히 필요로 한다. 상담에서 상담자와 내담자간의 역동적인 관계가 중요시되듯이 스포츠상담 역시 상담자와 내담자 간의 '개별적인 관계'가 가장 우선시 된다. Rogers의 인간중심적 상담은 상담자와 내담자 사이에서 일어나는 일치성, 공감, 무조건적 긍정적 보상을 통해 내담자의 성장을 촉진시킨다. 본 연구에서는 선수인 내담자와 스포츠심리학자인 상담자 간의 관계성을 이용한 Rogers의 인간중심적 상담 이론을 청소년 테니스 선수에게 적용하여 겪고 있는 심리적 어려움과 고민을 해결하고자 하였다. 피험자는 경력 5년째인 여고 1년생 1명이었다. 상담은 일주일에 1회씩 매 60-120분간 총 9회 동안 실시되었다. 상담내용은 모두 녹음, 녹취되었다. 9회의 상담내용 분석 결과, Rogers식 상담이 스포츠심리 영역에서 선수의 인지적, 행동적, 정서적 문제해결에 도움을 줄 수 있는 것으로 나타났다. Sport counseling is the act of giving counseling services to an athlete to form a solution to a problem. Athletes who join competitive sports confront various problems during the process of growth and development. Many of these problems may require a sport psychologist as a counselor to be properly dealt with. The dynamic personal relationship between counselor and client that is important in counseling is also important in sport counseling. Rogers' client-centered counseling encourages the growth of the client through congruence, empathy, and unconditional positive regard happening between counselor and client. In this research, Rogers' client-centered counseling was applied to young tennis athlete in order to solve their psychological difficulty and agony. Counseling was conducted on a weekly basis for nine, 60-120 minutes sessions. All counseling contents were recorded. The result of this study was as follows : It appeared Rogers' counseling therapy helped athletes to their cognitive, behavior and emotional problem solution at the sport psychology area.

甲狀腺機能亢進症을 同伴한 週期性痲痺의 1例

朴海珍 全南大醫大 1973 전남의대학술지 Vol.10 No.2

척수 외상의 자기공명영상 및 신경학적 소견 : Delayed MR Image and Correlated Neurology

박용규,정진명,김은상,김재일,송해룡,한종우,신형진 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.11

19 patients with traumatic spinal cord injuries and associated neurological deficit were examined by delayed(> 1 month) magnetic resonance imaging(MRI), the result of which were correlated with neurologic and somatosensory evoked potential(SSEP) findings. 5 different MRI patterns were observed in these patients : (1) normal signal intensity(SI) on T1-and T2-weighted images(WI)(pattern N/N, n=6), (2) normal SI on T1-WI and high SI on T2-WI(pattern N/Hi, n=3). (3) low SI on T1-WI and high SI on T2-WI(pattern Lo/Hi, n=6), (4) syrinx(n=2), and (5) cord transection(n=2). The neurologic state was determined using Frankel's classification at admission and MRI time. Pattern N/Hi had best neurologic state except pattern N/N, and pattern Lo/Hi showed worst prognosis except pattern transection. SSEP findings relatively well correlated with neurologic findings, but did not exactly. The cause is probably that SSEP shows predominantly the function of ascending sensory systems of the cord, do not reveal motor pathways, directly or indirectly.

들민달팽이(Deroveras varians)의 배자발육과 난황단백질

진병래,손흥대,박혜진,조은숙 東亞大學校附設 農業生命科學硏究所 1999 農業生命資援硏究 Vol.8 No.1

들민달팽이의 배자발육은 해부현미경으로 관찰하였다. 산란 후 4일이 경과면서 발육이 급격하게 진전되어, 10일이 지나면서 난 내에서 들민달팽이 유충의 형태를 갖추고, 12일째 부화하였다. 들민달팽이의 배자발육에 따른 난황단백질의 변화는 산란 1일째, 3일째 및 6일째 알의 난황단백질을 전기영동방법으로 분석하였다. 그 결과 배자발육과 함께 급격히 감소되는 난황단백질 관련 밴드를 관찰할 수 있었다. We characterized embryogenesis and egg proteins of Variable field Slug, Deroceras varians. The embryogenesis was observed by light microscopy. The eggs were hatched at the twelfth day after oviposition. The egg proteins of the first day, third day and sixth day after oviposition were analyzed by native-and SDS-PAGE analyses. The results showed that yolk proteins are gradually decreased during embryogenesis.

새로운 비선형 적응 등화기 설계

박동진,이재덕,양해권,안창선 群山大學校 情報通信技術硏究所 1998 情報通信技術硏究論文集 Vol.2 No.-

This paper presents adaptive equalizer using LMS(least mean squares) algorithms for adaptive nonlinear filters equipped with bilinear system models. Bilinear models are attractive for adaptive filtering applications because they can approximate a large class of nonlinear systems adequately, and usually with considerable parsimony in the number of coefficients required. The severity of the ISI is directly related to the spectral characteristics of the channel and not necessarily to the time span of the ISI. This paper reduces ISI of the nonlinear channel. This paper generated a nember of data from a received signalwaveform with a symbol and proposed a new adaptive equalizer to update adaptive parameter from this data and method to use protocol analyzer.

운동성 산화 스트레스와 항산화비타민의 보충이 말초단핵세포의 NF-kB 활성에 미치는 영향

진영수,박건구,박준영,김미정,이왕록,김혜영,이한준,박은경 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

Reactive oxygen species(ROS) are implicated in the pathogenesis of a wide variety of human diseases. Numerous studies indicate that ROS may serve as common intracellular molecules that contribute to the process of nuclear factor(NF)κB activation in response to a diverse stimuli. In our laboratory, we have demonstrated tat antioxidants could reverse the decline of immune function caused by exercise-induced ROS. Furthermore, it in necessary to understand a mechanism underlying ROS-dependent disorder in biological system. Recent studies have been shown that several gene expression were regulated by oxidants, antioxidants and other determinants of the intracellular reduction-oxidation(redox) state. In this process, NF-κB have been shown to play a important role. The purpose of the present investigation was to evaluate the effect of exercise-induced oxidative stress and antioxidnt supplementation on NF-κB activation in peripheral mononuclear cells. Forty male SD rats(4 weeks old) were randomly divided into noraml diet group and antioxidants(ATO) supplement group, and then ATO groups were treated with antioxidants(VE: 2001U/kg, VC: 50mg/rat, β-carotene: 300mg/kg, vitamin B6: 250㎍/100g, selenomethionine: 0.1mg/kg) for 16 weeks. After 16 weeks breeding at each condition, each group divided into two groups: Control group(CR) fed generally, Exercise group(CE) fed generally and followed by acute exercise 16 weeks later. Antioxidant Antioxidants and Exercise group(AE) fed with antioxidants and followed by acute exercise. The activation of NF-κB binding activity was increased after exhaustive exercise bout in both group. In addition, pretreatment of ATO group with the antioxidants mixture lead to the inhibition of NF-κB binding activity. This results suggest that NF-κB activation should be further studies in response to a variety of exercise.

Rigid Gas Permeable Contact Lens 재료물질에 관한 연구

朴惠正,朴景石,李原鎭 대구산업정보대학 1998 논문집 Vol.12 No.2

To improve the characteristic properties of contact lens materials, the copolymer of HEMA monomer NVP and MAOPTES monomer have been synthesized by the composition ratio of 50:45:5, 50:40:10 and 50:35:15. The copolymer of TMSOEMA monomer with HEMA and NVP have been synthesized as same compositional ratio as MAOPTES. Water content, swelling ratio, contact angle, permeability of oxygen and quantity of adsorptive protein were measured to check properties of copolymers. The experimental result measured for the copolymer containing silicon derivative of low ratio was prefered to be the materials of contact lens which can improve the function, due to the low absorption of protein compound to poly(HEMA) and to the high oxygen permeabilities