사인에 의한 즉시형 과민반응의 억제 효과

신태용,염정열,김원,김현미,박해정,장진이,조성룡,채병숙 우석대학교 생명과학연구소 1998 생명과학연구소 논문집 Vol.2 No.-

We investigated the effect of aqueous extract of Ammomum xanthioides(AXAE) on immediate hypersensitivity. AXAE inhibited systemic anaphylaxis induced by compound 48/80 in mice. AXAE inhibited serum histamine levels induced by compound 48/80 in mice. Moreover, AXAE dose-dependently inhibited histamine release in peritoneal mast cells activated by compound 48/80. These results indicate that the AXAE may be benificial in the regulation of immediate type allergic reaction.

한방병원에서 가정의학과 진료 내용 분석

원진숙,신선호,김혜정 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.2

Background: Recently social requirement for collaborated treatment of medical practice with oriental medicine has been increasing. This study is designed to provide the guidance of role of family medicine physician in oriental medicine hospital to help the establishment of interdepartmental cooperation between western and oriental medicines. Methods: Medical records of a total 973 patients administered in Chonju Oriental Medical Hospital of Wonkwang University from January Ito June 30 were reviewed. Data including sex, age distribution, periods of administration, past history, major clinical manifestations, diagnosis, laboratory tests, medications were collected and expressed as a percentage. The classification of Diseases was made according to ICPC. Results: Of 973 patients, sex ratio was 1:1.4 with female predominance and age distribution was highest in fifties and sixties (48%). Past history was dominated in cardiovascular disease (30.1%), postoperative sequele (16.4%) and diabetes (12.2%). Chief complains were ordered in frequency as arthralgia and myalgia (42%), hemiplegia (26%), dysphagia (17%), headache (13.8%), dizziness and vertigo (11.5%). Major diagnoses were cerebrosclerosis (39.7%), HNP (21.4%), cerebral hemorrage (11.2%) and arthritis (8.79%). Diseases of the administered patients were classified as cardiovascular (50.8%), musculoskeletal (31.8%), gastrointestinal (6.2%) and nervous systems. Conclusion: The main categories of the patients who were aided by family medicine physician in oriental medicine hospital were chronic debilitating diseases including cardiovascular disease and diabetes. To establish an effective collaboration of family medicine physicians in oriental medicine hospital, the doctors needed expert skills for treatment of supportive cares of chronic degenerative diseases and their complications.

원발성 폐암의 CT상 병기 결정:새로 재정된 TNM 체계와의 비교

신현준,최영칠,전혜정,박정희,김요한,이원진 건국대학교 의과학연구소 1998 건국의과학학술지 Vol.8 No.-

Accurate staging of lung cancer is essential for defining operability, selecting treatment regimens, predicting survival, and reporting comparable end results. Revisions in stage grouping of the TNM subsets in the International System for Staging Lung Cancer have been adopted by the American Joint Committee on Cancer and the Union Internationale le Cancer at 1996. We compared the previous TNM systems with revised stage grouping rules, and tried to applicate the new size-criteria for metastatic lymph nodes in mediastinum. Twenty-two patients were undergone CT stagings by using three different systems of previous, revised, and modified TNM subsets. Ten patients showed different TNM stage by the revised stage grouping rules and seven patients were altered in lymph node stage by the new size-criteria. Recognition of revised stage grouping rules is very important for treatment plan and predicting the correct prognosis.

Urapidil, Labetalol의 투여가 기관내 삽관시 심혈관계에 미치는 영향

신용섭,윤석화,손수창,이원형,이정은,황원재,김만수,김영주,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

We have examined the comparative efficacy of small doses of intravenous urapidil and labetalol in blunting hemodynamic response to endotracheal intubation and surgical incision in 30 patients without cardiovascular diseases. After intravenous urapidil 0.2 mg/kg or labetalol 0.2 mg/kg anesthesia was induced with thiopental 5mg/kg. Endotracheal intubation was facilitated by vecuronium 0.15 mg/kg with priming principle and anesthesia was maintained with enflurane and nitrous oxide in oxygen. Systolic, diastolic and mean arterial pressure and heart rate were measured before administration of the drugs, 5 minute after administration, just prior to endotracheal intubation and 1, 3, 5, 10 minute after intubatin. Also the peak blood pressures and heart rate within 10 minutes after surgical incision were measured. Endotracheal intubation and surgical stimulation were associated with significant increases in blood pressures and heart rate in both urapidil and labetalol group. Comparison of the changes in systolic, diastolic, and mean artrial pressures and heart rate between urapidil and labetalol group showed no significant difference except peak systolic pressure after surgical incision. It is concluded that the pressor response to endotracheal intubation and surgical stimulation are not influenced significantly by urapidil 0.2 mg/kg or labetalol 0.2 mg/kg. However, urapidil and labetalol preloading may be similarly effective in the blunting of the increases in blood pressures with larger doses of the durgs during anesthetic induction.

한랭노출과 고혈압의 연관성

장태원,김윤규,윤동영,이창희,홍영습,신해림,정갑열,김준연 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

Objectives : This study was carried out to suggest preventive methods for hypertension in cold-exposed workers. Methods : In 11 refs·iteration industries, 68 workers working in refrigerated areas more than one time per day were selected as the exposed group, and 68 workers not exposed to cold were selected as the control group. We interviewed the subjects with a questionnaire covering occupational history, and conducted clinical and laboratory tests including measurements of blood pressure and core temperature. Results : The systolic blood pressure in the exposed group(130.0±13.3 mmHg) was significantly higher than that recorded In the control group(118.3±12.1 mmHg), as was the diastolic blood pressure in the exposed group(82.7±8.5 mmHg) versus the control group(77.4±8.7 mmHg). The core temperature in the exposed group(36.1±0.7℃) was significantly lower than that experienced in the control group (36.4±0.5℃). In logistic regression analysis, age, cold exposure severity and milk intake were significant variables, with odds ratios of 5.204(95 % CI 1.440∼18.812), 2.674(95 % CI 1.080∼6.618), and 0.364(95 % Cl 0.141∼0.942) , respectively. Conclusions : Our study suggests that cold-exposed workers have higher a higher risk of hypertension, and that their core temperature is lower. Risk factors affecting hyper-tension of cold-exposed workers include age, cold exposure severity and milk intake. For the prevention of hypertension, cold-exposed workers should minimize cold-exposure time as much as possible.

KAL기 추락에 의한 대량재해의 개인식별

강신몽,이원태,고영창,최상규,김윤희,이홍석,서재관,윤중진,이혜경,최득린,김종열,윤창육,변명식,이장홍 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2

Individual identification is an important part in medicolegal field especially in mass disaster. At July, 27, 1989, KAL KE-803 was crashed on landing at Tripoli International Airport, Liba. The plane was caught in fire and sixty eight Koreans were sacrified. The majority of victims were severely charred and injured. The authors examed all dead bodies and successfully identified all the cases through visual, anthropological, odontological, radiological and pathological methods including fingerprint and blood typing.

고농도 용액의 침지시 감자 절편의 탈수모델에 관한 연구

최동원,신해헌 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.6

감자절편를 고농도용애에 침지하여 탈수시킨 결과 침지용액을 구성하는 용질의 분자량에 따라 탈수 형태가 다르게 나타났다. 저분자 용액 인 NaCl. PEG 400 용액에 침지만 경우 조직의 뒤틀림현상(cytorrhysis)은 나타나지 않고 부피의 감소와 수분의 탈수현상이 나타난 반면 고분자 용액인 PEG 4000, PEG 6000용액에 침지한 경우cytorrhysis 현상을 동반한 부피의 감소와 탈수현상이 나타났다. 초기 탈수속도는 저분자용액에 침지시 더 빨랐으나 최종 탈수량은 고분자 용액에 침지시 더 컸다. 고장성 용액에 감자절편을 침지시켜 탈수되는 기작이 두가지 압력(삼투압, 분자압착력)에 의해 진행된다고 가정하고 모델을 제안하여 검정한 결과 제안된 모델은 고분자 용액에 침지시의 탈수현상을 설명하는데 적합하였다 모델에서 구해진 압력인자(ΔP)와 농도인자(a)는 온도(T)와 농도(C)의 함수로 표현되며 계수의 탄력성 검정결과 농도에대한 의존성이 더 큰 것으로 나타났다. To investigate the effect of molecular size of solute of solution where which potato slices were soaked. In the case of soaking in low molecular solution like NaCl and polyethylene glycol(PEG)400 solution only plasmolysis was observed. However in high molecular solution like PEG4000 and PEG6000, cytorrhysis was observed. Initial dewatering rate was faster when soaked in low molecular solution but total amount of removed water was larger in high molecular solution. Suggested model fitted well dewatering phenomena when soaked in high molecular solution. Pressure factor and concentration factor was more dependent on concentration of soaking solution than soaking temperature.

공원묘지 유실에 의한 대량재해의 개인식별

강신몽,이한영,윤중진,이원태,김종열,이영석,서재관,최득린,서지석,이혜경 大韓法醫學會 1992 대한법의학회지 Vol.16 No.1

Individual identification of severely decomposed or skeletonized bodies is an important part in medicolegal field. 142 bodies were torn up and carried away by flood in a park cemetry, Kwang-Ju, Kyunggi province, Korea at Sept., 10, 1990. The authors examed the 56 bodies, which were gained, through medical, anthropological, odontological, radiological methods, and superimposition for individual identification. Among them, 41 cases were successfully identified, and remaining 15 cases were not identified because of sever destruction and no adequate information.

객체지향형 교육용프로그래밍언어 두리틀의 다중 예약어 지원 체계

최해심,권대용,김형신,염용철,유승욱,이원규 한국컴퓨터교육학회 2005 컴퓨터교육학회 논문지 Vol.8 No.2

초·중등 음악교과 담당교사의 개별화 수업에 관한 인식 및 요구

최은식,신혜경,정진원 이화여자대학교 교과교육연구소 2014 교과교육학연구 Vol.18 No.1

학습자가 자기 주도적으로 지식을 형성해가는 현대의 구성주의교육에서 학습자의 개별적 특성의 수용은 교수-학습에 영향을 끼치는 중요한 요인으로 주목을 받아왔다. 이러한 맥락에서 본 연구는 학습자의 개인차를 수용하기 위한방법인 개별화 수업에 대한 초·중등 음악교과 담당교사의 인식 및 요구를 비교하는 것을 목적으로 한다. 본 연구의 방법은 조사연구이며, 설문 도구는 수업요인, 교사요인, 학생요인, 시설·환경요인, 학교 교육과정 편성·운영요인의 범주로 개발되었다. 연구대상은 음악교과 지도 경험이 있는 전국의 초등학교 교사와 중학교 음악교사 216명이었으며 분석 결과는 다음과 같았다. 첫째, 초등학교와 중학교 음악교과담당교사들은 음악수업 가치의 우선순위와 평가기준의 상세화정도, 평가의 우선순위에 대하여 인식의 차이를 보였다. 둘째, 개별화교수법의 활성화를 위한 교사증원과 교사전문성 지원 프로그램 확대에 대해서는 중학교 교사들의 요구가 초등학교 교사들에 비하여 더 높게 나타났다. 셋째, 학생들의 음악 수업에 대한 이해도는 초등학교 음악교과담당교사들이 중학교 음악교사들보다더 높게 인식하는 것으로 나타났다. 학생들의 개인차를 반영한 음악 수업자료는 중학교 음악교사들이 초등학교 교사들보다더 활발하게 사용하는 것으로 나타났다. 넷째, 개별화 수업을 위한시설·환경적 요인에 대하여 중학교 음악교사의 요구가 초등학교 교사들의 요구보다 매우 높게 나타났다. 다섯째, 학교 교육과정 편성·운영요인에 관한 음악교과 담당교사들의 인식 및 요구를 비교한 결과는 다음과 같았다. 집중이수제는 초등학교보다 중학교 음악 수업에 매우 높은 비율로 시행되고 있었다. 음악 수업시수 확대에 대한 중학교 음악교사의 요구가 매우 높게 나타났다. 개별화 수업의 활성화를 위한 국가차원의 행정 및 재정지원에 대하여 중학교 음악교사들의 요구가 초등학교 교사들보다 더 높은 것으로 나타났다. 본 연구는 개별화음악 수업에 대한 현장 교사의 관점을 수용한 연구로서 추후 음악교과 관련 정책수립 시 학교급별 차이를 반영할 필요를 시사한다. The purpose of this study was to compare elementary and secondary music teachers’perceptions and needs with respect to differentiated instruction. The researchers developed a questionnaire to examine the factors of instruction, teacher, learner, learning environment, school curriculum, and policy. The participants in this survey were 216 elementary and middle school music teachers nationwide. Based on the survey results, the conclusions were as follows: first, the elementary and secondary music teachers showed differences in their perspectives regarding the value of instruction and the priority of assessment and evaluation. The secondary music teachers created more detailed evaluation criteria, which considered students’ individual differences, than the elementary teachers. Second, the secondary music teachers demonstrated more interest in opportunities for the teacher professional development such as workshops related to differentiated instruction than elementary teachers. They also showed stronger needs for an increase in the number of music teachers than the elementary teachers. Third, the elementary teachers strongly felt that their students understood the content of instruction compared to the secondary music teachers. The secondary music teachers applied teaching and learning materials that reflected students’ individual differences more than the elementary teachers. Fourth, the secondary music teachers showed stronger needs for constructing networks based on the local resources and for centers for music instruction that supported differentiated music instruction. Lastly, in consideration of the differences in their students’individual musical abilities, the secondary music teachers indicated a stronger necessity for increasing class hours for music, as well as political and financial support.