난소의 유피낭포에서 발생한 편평세포암종 1례

최병관,정일균,최동수,목정은 慶熙大學校 1984 論文集 Vol.13 No.-

A case of squamous cell carcinoma arising in dermoid cyst of the ovary is presented with a brief review of the literatures.

수면량과 집중력의 상관관계

김병우,류지근,박우진,박계원,김미정,임지은,백대현,최재덕,최윤호,이가현,이관,김덕수 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

수면, 기억 그리고 학습의 연관성은 실제 매우 복잡하다. 많은 연구에도 불구하고 명확한 연구결과는 아직 없다. 우리는 이 연구에서 평소와는 달리 시험 전날 수면 변화 양상이 집중력에 어느 정도 영향력을 미치는지 알아보고자 하였고, 이를 이용해 효율적인 수면 관리를 할 수 있는 기초자료로 삼고자 하였다. 동국대 의대 본과 1학년생 중 지원자 30명과 본과 2학년생 10명을 대상으로 평상시 상태와 시험 직후 수면이 부족한 상태에서 각각 K-PES TEST를 실시하여 총 8항목에 걸쳐 암기력, 판단력, 단순반응의 변화정도를 검사하였다. 또 설문조사를 병행하여 결과에 영향을 미칠 수 있는 다른 인자들도 파악하였다. 수면량에 대한 부호 숫자 짝짓기(순간 판단력)을 검사한 결과, 인간의 최대 생리학적 기능은 꼭 수면부족에 의해 좌우되는 것은 아니다. 그러나, 수면감소는 피로를 증가시키고, 동기부여를 감소시키나 단, 새로운 사실을 학습하는 데에는 큰 영향을 끼치지 않는다. 즉, 수면부족으로 장시간 깨어있는 것은 정확성과 반응성을 떨어뜨린다. 흡연에 대한 부호 숫자 짝짓기(순간 판단력)을 검사한 결과, 니코틴의 수면에 대한 상호관계는 알려지지 않았고, 인간의 감정이나 의식, 인식에 영향을 주는 것으로 알고있지만, 장기적은 측면에서 흡연이나 알코올은 인식능력과 무관한 것 같다. 카페인에 대한 숫자 외우기(암기력)검사 결과, 카페인은 spacial selective attention에는 특별한 영향을 주지 않지만 지각과정이나 주의 집중에 큰 효과를 주며, 인간의 의식 수행에 긍정적인 효과를 준다. 즉 카페인은 활력, 혼란, 피로상태를 변화시키고 visual analog scales에서 휴식상태에 가까운 양상을 나타낸다. 또 48시간 동안 수면을 취하지 않은 사람에게 카페인은 집중력과 장시간의 좋은 기분을 유지하게 하였다. 그러나 규칙적, 비규칙적으로 먹는 사람간에는 인지수행력의 차이를 보이지 않으며 상용자에서는 상당한 내성이 보인다. 수면패턴에 대한 숫자 더하기(순간 판단력)검사 결과, 집중력은 수면패턴에 의해서도 영향을 받고, 수면패턴이 바뀌게 되면 순간판단력을 저하시킨다. This study was performed to evaluate relationship of sleep and attention, and to control sleep effectively. We conducted a K-PES test of 40 medical students. K-PES contains eight elements, for example, simple response, selective response, color pairing, OddEven discrimination, number addition, number-symbol matching, memory, right-tapping, left tapping. Through these, we tested changes of memory, judgement, simple response. And we conducted a questionnaire survey to exclude bias. Results are as follows. As a results of number-symbol matching test, we know that sleeplessness is not complete responsible for physiologic function for humans. But, decreased sleep increases fatigue and decreases motivation, but no influence on learning new materials. So, long term sleeplessness decreases precision and responsibility. As a results of number-symbol matching test on smoking, a relationship of nicotine and sleep is not certain. A point of view in long term period, smoking and drinking is not related cognition, even if we know that those influence mood, consciousness and cognition. As a results of memory work test on caffeine, caffeine does not influence spacial selective attention, but mainly does perception, attention and consiousness process. Namely caffeine changes energetic activities, chaos, fatigue states and shows resting state in visual analog scales In sleeplessness for 48 hours, caffeine produced attention and good mood for a long time. But, in case of cognitive process no significance shows in regular or irregular diet. Regular diet shows high resistance. As a results of number addition test on sleep patterns, seep patterns influence attention, changes of sleep patterns decrease a moment judgement.

자동차용 발전장치의 특성 시험설비 개발

차귀수,박두순,최관순,이병수 순천향대학교 1990 논문집 Vol.13 No.2

The objectives for this project is to develop the test equipment of the automobile alternator's characteristics. The main activities and the results of this project are summarized as follows. 1. State-of-the art analysis of automatic test equipment for factory automation. 2. System analysis and design the test equipment of the automobile aiternator's characteristics. 3. Development of software for the alternator's performance test. 4. Development of hardware for control system. 5. Total system integration test. We developed the automatic test equipment for automible alternator's characteristics with personal computer which basis on the microprocessor pheriperal devices and sensing devices. We hoped that our developed systems are very useful in automobile alternator's test equipment and that the interest for factory automation is incresed in industry environments.

방사선치료와 화학요법을 받은 유방암 환자에서 발생한 발치 후 종창의 진단영상학적 감별 진단

허경회,안병모,김미자,박관수,허민석 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.36 No.3

A 60-year-old female, who complained of delayed healing and swelling after extraction of left lower second molar during chemotherapy, visited our department. She had a history of a resection surgery of breast cancer and postoperative radiotherapy. The conventional radiographs showed diffuse permeative bone destruction in posterior mandibular body, which gave the first radiologic impression of osteonecrosis associated with radiotherapy or chemotherapy. And bone metastasis from the breast cancer was also considered in the differential diagnosis. On the enhanced computed tomography (ECT) the posterior mandibular body was occupied by a large expansile lesion showing central low attenuation with peripheral rim enhancement. Magnetic resonance images revealed that the low attenuated area on ECT did not show as high signal intensity as water on T2 weighted image and indicated solid component of a tumor. The final diagnosis was central squamous cell carcinoma. We present the diagnostic imaging features of the patient with special emphasis on the differential diagnosis.

금속사출성형에 의한 중합금 소결체 부품 제조에 관한 연구

여환균,김병진,김길수,김성훈,송준호,한관희 嶺南大學校 工業技術硏究所 2003 工業技術硏究所論文集 Vol.31 No.2

In this study we demonstrate that a small complex part of a tungsten-based heavy alloy (W-Ni-Cu) can be readily manufactured by utilizing the metal injection molding (MIM) technology. We use a simple thermoplastic binder system, containing low density polyethylene, paraffin wax, and stearic acid. To remove the organic binder from the molded part, we employ the solvent extraction and thermal debinding processes. Densification of debound parts is achieved by sintering in hydrogen atmosphere. The experimental results of the optimization of process variables to manufacture the heavy alloy part are described, with a brief discussion.

상부위장관 출혈 원인의 변화 양상

김태년,도병수,김현정,이삼범,정문관 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Upper gastrointestinal(UGI) bleeding was critical disease that was commonly found in emergency department and needed more early diagnosis and rapid treatment for decreasing mortality and morbidity. It's causes and frequencies were affected by many factors, but the majorities were caused by peptic ulcers and esophageal-gastric varices. With development of economy and medical services, new drugs and endoscopic interventions, the treatment of patients with UGI bleeding was more improved. So I would like to evaluate the change of causes and frequencies of UGI bleeding and the associated clinical findings. A total of 1,546 patients presented with UGI bleeding in emergency department of Yeungnam university hospital during the five years from Jan. 1991 to Dec. 1995 were clinically reviewed by chart and compared with previous seven years report from Jan. 1984 to Dec. 1990 in the same hospital. The ratio of male to female was 6.1:1 and slightly increased in comparison with previous seven years. The incidences in 6th and 5th decades were highest(54.4%)as like as previous seven years. Age distribution of duodenal ulcer bleeding, Mallory-Weiss tear and acute gastric mucosal lesion were developed in lower decades than the others. The causes of UGI bleeding were caused by esophageal varix(45.4%), peptic ulcer(38.8%), Mallory-Weiss tear(4.3%), gastric cancer(3.8%), other(3.1%), acute gastric mucosal lesion(2.7%), undetermined causes(1.8%) in descending order of frequencies. The proportion of esophageal varices was increased from 36.6% to 45.4%, but that of peptic ulcer was relatively decreased from 47.6% to 38.8%. And the annual distribution of varices was increased, however the annual distribution of peptic ulcers was increased. Although the ranking of annual distribution of gastric ulcers and duodenal ulcers were not changed compared to previous study and the frequency of gastric ulcers was increased since 1992, but additional follow-up was needed. Seasonal variations were found that upper gastrointestinal bleeding was increased in fall and peptic ulcer bleeding was increased significantly in summer and fall, however, varix bleeding was less frequent in summer time as like as previous seven years. Emergency endoscopic examination was performed within 6 hours for 54.5%, 24 hours for 90.8% and this results were to be like previous results, 57.5% and 90.7 respectively. Findings of emergency endoscopic examination were active bleeding focus(21.2%), blood clot(7.9%), exposed vessels(13.3%), flat blood spot(6.4%) and lesion without evidence of bleeding(51.3%). Endoscopic findings of active bleeding were easily seen when examination was perfomed within 24 hours. Blood transfusion was performed in 67.3% with average 2.1 units. When the causes of bleeding were due to varix and marginal ulcer, more amounts of blood were transfused than the others. In previous seven years, blood transfusions were performed in 71.2% with average 5 units and more amounts of blood were transfused in gastric cancer and varix bleeding.

도금사업장의 작업환경의 유해인자 노출수준에 관한 연구

문덕환,도수영,이채관,황용식,선병관,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objective : For the purpose of preparing the fundamental data and assessing the status of exposure level of chemical substances and physical agents. Methods and Material : Such as noise, two types of dust, four types of metals, seventeen types of organic solvents, and four types of other materials classified by specific chemical substances in 21 metal product plating factories classified by 28 processes. The author determined exposure level on those hazardous materials from Jan. to Dec. 2001. Results : The results were as follows: 1. The exposure level for noise was exceeded to Threshold Limit Value(TLV) in the process of 6 cases of Machining, 5 and 4 cases of pre and post-buffing, and 6 cases of waterdrop-removing, the mean noise level of all of processes was not exceeded to compliance level. 2. The exposure level for dust was not exceeded to TLV at all. 3. The exposure level for Chromium(Cr) was exceeded to TLV in Chromium plating process, metal exposure level including Zinc(Zn), Manganese(Mn), and Lead(Pb) was not exceeded to TLV. 4. The exposure level of toluene in case of organic solvents was exceeded to TLV in 1 case of finishing/cleaning, coating/developing process, respectively. 5. The exposure level of four types of other materials classified by specific chemical substances were not exceeded to TLV. 6. The exposure level for dust and metal including Zn, Mn, and Pb was decreased in comparison with two results of air monitoring performed. There was no difference of the exposure level for Cr, noise, and four types of other materials classified by specific chemical substances, and the exposure level for organic solvents was slightly increased. 7. The exposure level for noise in factories employing more than 21 workers was higher than that for noise in foadtories employing less than 20 workers. The more workers, the lower exposure level in metal including Zn, Mn. The exposure level for Cr was increasing in factories employing more than 51 workers, and the more workers the lower exposure level in organic solvents. Conclusion : According to above results, this study suggests positive work environment managements in processes exceeding exposure limit value as well as continuously consecutive work environment management in processes not exceeding exposure limit value and revealing no chronological difference of exposure level should be needed.

파쇄골 이식술을 이용한 안정된 무시멘트 비구컵 주위의 골융해에 대한 치료

서유성,임강철,권혁룡,임수재,박종석,이병일 대한고관절학회 2003 Hip and Pelvis Vol.15 No.3

원자력 발전소 근로자에서 업무상 질병으로 인정받은 급성 골수성 백혈병 1예

임현술,정해관,김수근,박병찬,이관 약업신문사 1983 의약정보 Vol.9 No.-

원자력 발전소 근로자에서 업무상 질병으로 인정받은 급성 골수성 백혈병 1예

임현술,정해관,김수근,박병찬,이관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.2

저자들은 10여 년 동안 원자력 발전소 협력업체에 종사하면서 저선량의 방사선에 노출된 근로자로 급성 골수성 백혈병으로 진단 받고 사망 후 업무상 질병으로 인정된 증례를 보고하는 바이다. 증례에 대한 의무기록과 혈액검사 및 조직검사, 세포유전학 검사를 검토하였으며 환자의 작업 내역, 방사선 피폭량 및 동료 근로자에 대하여 조사하였다. 환자는 35세 남자로 1997년 11월 20일 경북 포항시 소재 D 대학병원에서 용접공에 대하여 실시하는 기타 중금속 특수건강진단(망간)에서 백혈구 수가 μL당 108.9×10³개, 혈색소는 8.6g/dL로 급성 백혈병을 의심하였다. 11월 24일 대구광역시에 위치한 K 대학병원을 방문하여 급성 골수성 백혈병으로 확진되었다. 골수검사에서 이소성 B 임파구성 표지자를 지닌 AML M2로 진단되었고, 염색체 검사에서 필라델피아 염색체가 발견되었으며, 46 XY t(1:4)(p32:p16)의 소견을 보였다. 항암 화학요법을 시행하였고 주기적인 항암 약물요법과 추적 관찰을 시행하였다. 1999년 5월 30일 급성 골수성 백혈병에 의한 합병증인 폐렴 및 패혈증으로 사망하였다. 본 증례의 방사선 피폭량은 1,853 mRem (18.53 mSv)이었으며, 방사선에 의한 암발생 원인확률은 미국 기준으로 5.4-6.1%이었다. 우리나라는 업무상 질병인정 기준에 방사선 노출에 의한 백혈병이 인정된다고 명시하고 있어 업무상 질병으로 인정되었다. 그러므로 우리나라 실정에 맞는 전리방사선 피폭량에 따른 업무상 질병 인정기준을 설정하여야 하며 방사선 피폭 근로자에 대하여 방사선 질환의 감시체계를 운영하여야 한다. Acute myelogenous leukemia (AML) has been known as an occupational disease induced by irradiation. We report a case of acute myelogenous leukemia with a history of low dose irradiation in a nuclear power plant. The authors reviewed the clinical and hematologic features of the case. We also reviewed the job contents of his workplace. We also interviewed other workers in the same workplace. The amounts of radiation exposure were reviewed. The worker was a 35-year-old male who had worked in a nuclear power plant for 11 years (1987-1997). Total amounts of radiation exposure during the work period was 1,853 mRem. He had been diagnosed as AML on November, 1997 at a routine periodic health examination. He died of refractory leukemia on May, 1999. The AML developed in this patient seems to be related to the exposure to radiation. To prevent irradiation injury, we must modify work procedures, begin comprehensive medical surveillance, educate workers on risks of radiation, and increase workers awareness of safety regulations in the workplace.