신라 중고기골제(中古期骨制)의 성립과 운영

박수진 ( Soo Jin Park ) 수선사학회 2011 史林 Vol.0 No.39

The Golpum system was the unique form of the status system in the Silla dynasty in Korea. It was a typical ancient Korean society`s status system which has been investigated field in the academia. In particular, a kinship system, which is composed of Seong-gol and Jin-gol, is the most hottest issue in the Korean academic circles. However, there is a no point of agreement whether Seong-gol was the reality or not, and concerning about its management and times. This research has a purpose to investigate how the status system established and guaranteed in the society. The Buddism has attracted public attention as a theoretical basis of the status system. The Samkuksagi (The chronics of the three nations) described the Buddism as a state religion while it did not focus on the myths about the Buddism. We assume that the Buddism was the meaningful political controller in the Silla dynasty. Seong-gol was regarded as the royal familiy, and it was available when the King had the superiority over the nobility. The Kings of Sylla dynasty had been called the Great King with a qualifier ``saint`` when the Buddism instituted a state religion. It means that Seong-gol (the saunt family) was established based on the Buddism. Jin-gol also entered a field of history similar times to Seong-gol, and both two terminologies was established the same period in terms of the Buddism terminology. Seong-gol guaranteed a royal family`s prestige through the change of ennoble system Galmun King and the use of the Great King title. The King`s brother, who were Seong-gol, secured the superiority over the nobility by getting the title of ennoblement. The Kings also solidified their status through the ennoble system, and they monopolized political power because the kings restrained the right of succession only kings heirs. Jin-gol also guaranteed their political prestige after established Daedeung. The House of Lords in Silla dynasty limited the qualification only who had the title of Daedeung. Jin-gol class took the reins of the nobility through only Jin-gol getting the title of Daedeung.

Differential Manifestation of Ocular Phenotypes in TALEN-mediated p19arf Knockout FVB/N and C57BL/6J mouse lines

Jin‑Sung Park,Joo‑Il Kim,Hyun‑Jin Lim,Soo‑Kyung Ryu,Euna Kwon,Kang‑Min Han,Ki‑Taek Nam,Han‑Woong Lee,Byeong‑Cheol Kang 한국유전학회 2020 Genes & Genomics Vol.42 No.9

Background p19arf, primarily known as a tumor suppressor, has also been reported to play an essential role in normal development of mouse eyes. Consistently, lack of p19arf has been associated with ocular defects, but the mixed background of the knockout (KO) mouse strain used raised a concern on the accuracy of the phenotypes observed in association with the targeted gene due to genetic heterogeneity. Object We carried out a study to investigate into the efect of genetic background on the manifestation of p19arf KO associated phenotypes. Methods We characterized the phenotypes of novel p19arf KO mouse lines generated in FVB/N and C57BL/6J using a transcription activator-like efector nuclease (TALEN) system in comparison to the reported phenotypes of three other p19arf-defcient mouse lines generated using homologous recombination. Results Ninety-fve percent of FVB/N-p19arf KO mice showed ocular opacity from week 4 after birth which worsened rapidly until week 6, while such abnormality was absent in C57BL/6J-p19arf KO mice up to the age of 26 weeks. Histopathological analysis revealed retrolental masses and dysplasia in the retinal layer in FVB/N-p19arf KO mice from week 4. Besides these, both strains developed normally from birth to week 26 without increased tumorigenesis except for a subcutaneous tumor found in a C57BL/6J-p19arf KO mouse. Conclusion Our fndings demonstrated surprisingly variable manifestation of p19arf-linked phenotypes between FVB/N and C57BL/6J mice, and furthermore between our mouse lines and the established lines, indicating a critical impact of genetic background on functional study of genes using gene targeting strategies in mice.

비병원성 야생효모로부터 알칼리성 단백질분해효소 생산

문정수, 박경서, 공유리, 김수진, 이종수 배재대학교 자연과학연구소 2022 自然科學論文集 Vol.33 No.1

Conceptual Study for Tissue-Regenerative Biodegradable Magnesium Implant Integrated with Nitric Oxide-Releasing Nanofi bers

Jin‑Kyung Jeon,Hyunseon Seo,Jimin Park,Soo Ji Son,Yeong Rim Kim,Eun Shil Kim,Jong Woong Park,Woong‑Gyo Jung,Hojeong Jeon,Yu‑Chan Kim,Hyun‑Kwang Seok,Jae Ho Shin,Myoung‑Ryul Ok 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.4

The excessive initial corrosion rate of Mg is a critical limitation in the clinical application of biodegradable Mg implantsbecause the device loses its fi xation strength before the fractured bone heals. This study suggests a new approach to overcomethis hurdle by accelerating tissue regeneration instead of delaying the implant biodegradation. As angiogenesis is anessential process in early bone regeneration, a Mg implant coated with electrospun nanofi bers containing nitric oxide (NO),which physiologically promotes angiogenesis, is designed. The integrated device enables adjustable amounts of NO to bestored on the NO donor-conjugated nanofi ber coating, stably delivered, and released to the fractured bone tissue near theimplanted sites. An in vitro corrosion test reveals no adverse eff ect of the released NO on the corrosion behavior of the Mgimplant. Simultaneously, the optimal concentration level of NO released from the implant signifi cantly enhances tube networkformation of human umbilical vein endothelial cells without any cytotoxicity problem. This indicates that angiogenesis canbe accelerated by combining NO-releasing nanofi bers with a Mg implant. With its proven feasibility, the proposed approachcould be a novel solution for the initial stability problem of biodegradable Mg implants, leading to successful bone fi xation.

Cellulase 생산 야생효모의 선별 및 세포외 Cellulase 생산

문정수, 박경서, 김혜원, 김수진, 이종수 배재대학교 자연과학연구소 2016 自然科學論文集 Vol.33 No.1

신성고혈압쥐에서 혈관내피층이 Phorbol Ester에 의한 수축에 미치는 영향

정수아,김형,차경훈,전제열,윤평진,염철호,박진,조남수,홍순표 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.11

혼수상태의 외상환자에서 초음파를 이용한 흉부 및 복부손상의 진단

임경수,이강현,이진웅,이부수,황성오,유수영,강성준 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

The need for rapid diagnosis and treatment of life-threatening thoracic and intra-abdominal injury result in controversy over the appropriate triage of unconscious blunt trauma patients. To aid in early decisions for these patients, a prospective analysis of 98 patients with glasgow coma scale(GCS) scores≤8 was undertaken. Although intra-thoracic and intra-abdominal injuries were frequently identified based on systolic blood ressure, the use of clinical signs alone resulted in more missed injuries than did using the emergency ultrasonography. In normotensive patients(n=34), intra-thoracic injuries was identified in one patient(2.9%), and intra-abdominal injuries were in 7 patients(20.6%). In shock(systolic blood pressure<90mmHg) Pa-tients(n=64), thoracic injuries and intra-abdominal injuries were diagnosed in 8(12.5%) and 27 patients(42.3%), thoracic and abdominal combined injuries were identified in 11 patients(17.2%). The sensitivity, specificity, and accuracy of emergency ultrasonography were 96.3%, 91.7%, 94.9%. This study suggests that all unconscious trauma patients undergo immediate emergency ultrasonography to prevent missing life-threatening injuries.

화제와 화제전환 : 한국 현대 소설을 중심으로

김진수 한국현대언어학회 2001 언어연구 Vol.17 No.1

This study is aimed to investigate the concept and topic shifting in the Korean Modern Novels. This study is focused on the shifting of topic in novels which is closely connected with Kim Jin-Soo(2000)'s. The concept of topic is divided into two types in this study; The topic on the sentential level which is named 'comment' in novels. The other is a discourse topic of conversational level. It(the topic) must have topicality, coherence, focality. A topic is not decided by sentential level, it is always done by context. Also the shifting topic of discourse is occurred on the point of the starting speech or the restarting speech in the speech transition structure.

병원에서 사용된 백신양으로 평간한 예방접종 실태

김정수,백용수,정문현,이진수,오경선 대한감염학회 2008 감염과 화학요법 Vol.40 No.3

Background : Studies on immunization in Korea mainly focus to the coverage rates in recipients. The attitudes of health-care providers regarding immunization are rarely evaluated. Therefore, to assess the pattern of vaccine administration by health-care personnel, the vaccine consumption in a university hospital was investigated. Materials and Methods : The vaccine consumption in a university hospital during 2 months (September and October) in 2 years (2002 and 2007) was evaluated. September is representative of months when influenza vaccine is not available, whereas October is representative of months when influenza vaccine is available. These monthly data were summarized by departments and vaccines. Results : Vaccine consumption over the 5-year period increased primarily because of the increased use of the influenza and tetanus-diphtheria (Td) vaccines in adults. In 2007, the most frequently administered vaccine during the influenza season was the influenza vaccine, followed by the Td vaccine. In the same year, the Td vaccine was the most frequently administered vaccine during the non-influenza season. Compared to 2002, there was a marked increase in the use of the hepatitis A virus (7-fo1d), Japanese encephalitis (6-fo1d), and pneumococcal polysaccharide (3-fold) Vaccines in 2007; the Td, meningococcal, and pneumococcal protein-conjugated vaccines were not available in 2002. In adults, pneumococcal vaccination was increasingly prescribed concomitant with the increased influenza vaccination: a similar trend was not observed in children. The use of vaccines in most departments was confined to the influenza vaccine, and the majority of Td vaccine was consumed in the emergency department. As compared to the internal medicine and family medicine departments, fewer vaccines were prescribed by the neurology, surgical, and minor specialty departments, especially in the non-influenza season. Conclusion : Although vaccine consumption increased during the 5-year period, the increase was attributed to the increased consumption of the influenza vaccine. Promotion and education regarding the use of non-influenza vaccines are needed. 배경 : 국내에서 백신 사용은 접종을 받은 사람에서만 조사가 되었고, 예방접종 제공자에서 조사가 적었다. 앞으로 백신 접종률을 높이기 위해서는 접종자에 대한 연구도 있어야 하며, 병원 단위에서 백신 사용 양상을 알기 위해 대학병원에서 백신 사용량을 조사하였다. 재료 및 방법 :2002년과 2007년의 9월과 10월에 약제부에서 사용된 백신 양을 조사하였다. 9월은 인플루엔자 백신이 없는 달을 대표하는 달이고 10월은 인플루엔자 예방 접종이 가능한 달을 대표한 것이다. 월별 백신 소모량을 과별, 백신별로 정리를 하였다. 결과 : 2002년에 비해 2007년에는 백신 사용량이 1.6배 증가했으며, 인플루엔자 백신과 Td의 사용 증가가 주요 이유였다. 인플루엔자 백신 접종 시기에는 인플루엔자 백신 사용량이 제일 많았고, 두 번째 많이 사용되는 백신은 2002년에는 B형 간염 백신이었고 2007년에는 Td였다. 성인에 서는 인플루엔자 백신 사용과 함께 폐렴사슬알균 백신 사용량이 늘었지만 소아에서는 이런 경향이 보이지 않았다. 인플루엔자 백신 접종 시기인 10월에는 소아과에서 사용보다 비소아과에서 백신 사용량이 더 많았다. 과별로 보면 대부분 과에서 인플루엔자 백신이 주로 사용되었고, 응급실에서는 Td만이 사용되었다. 신경과와 재활의학과, 외과계열, 소수과에서 사용이 적었다. 결론 : 예방접종이 5년 사이 증가하였으나 인플루엔자 백신에 국한된 양상을 보였다. 인플루엔자 백신과 파상풍-디프테리아 백신뿐만 아니라 다른 백신에 대한 홍보가 필요하다.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.