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서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)
김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3
Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.
일 간호대학의 간호환경시스템 통합실습방안 적용 : 간호관리학과 지역사회간호학의 통합
김광숙,이경자,김의숙,이정렬,김인숙,이태화,조윤희,정제인,이현정,배선형,김은현 대한간호학회 간호행정학회 2008 간호행정학회지 Vol.14 No.1
Purpose: Integrated curriculum has been considered as a desirable method in health related school course. The present study was conducted to develop practice curriculum which integrates nursing management and community health nursing and measure the education effect. Method: Literature review and scores of professional meeting were carried out to generate main educational goals, contents, operating principle, and evaluation item. Student evaluation was done by survey and in-dept interview in right after practicum and three months respectively. Results: Six concepts were derived as main component of the integrated curriculum. From 2 to 3 sub-categories were matched to each main component as well. Subsequently, practice contents were suggested on the basis of sub-categories. Attainment of practicum goal scores ranged from 2.82 to 3.54 in four points index. Students expressed that they found nursing manager's role in the community setting. Conclusion: This new approach encouraged students to ascertain relationship between hospital oriented and community based practice. Additionally, they can be prepared to comprehend diverse health care environment.
Productivity S/W 학습용 웹 코스웨어에서 상황맥락적 오류교정 패드백이 학업성취도에 미치는 영향
김도윤,배영권,백장현,이태욱 한국컴퓨터교육학회 2004 컴퓨터교육학회 논문지 Vol.7 No.1
현재 웹 코스웨어에서의 형성평가와 이에 대한 피드백 시스템은 많이 구축되어 있다. 그러나 대부분 웹 코스웨어의 형성평가와 사용자 반응에 따라 제공되는 피드백은 실제의 문제 상황과 거리가 먼 상태에서 단순한 텍스트 형태로 정오의 표시, 정답 표시, 관련 정보의 표시 등을 제공하고 있다. 이는 자칫 피드백의 교정적 기능을 약화시켜 학습자의 학습 내용에 대한 이해와 학습 전이의 가능성을 감소시킬 수 있다. 또한 구성주의 학습이론에 따르면 학습은 그 것이 발생하는 상황에 영향을 받고 지식이 어떤 맥락에서 학습했느냐에 따라 다르게 학습되며 전이된다고 한다. 이런 배경에서 본 연구는 웹 코스웨어에서 형성평가를 실시할 때 학습자의 반응에 따라 피드백을 문제 상황과 밀접하고 유사하게 상황맥락적으로 제시할 수 있는 상황맥락적 오류고정 피드백시스템을 설계하고 구현하였다. 그리고 실제 Productivity S/W를 학습할 수 있는 웹 코스웨어에 ‘정오/정답제공형 피드백', ‘관련정보제공형 피드백’‘상황맥락적 오류교정 피드백’을 적용한 후 ‘상황맥락적 오류교정 피드백’이 학업 성취에 있어서 다른 두 가지 유형의 피드백보다 더 효과적인지를 검증하였다. Today there are many Web courseware systems for formative evaluation and feedback. Formative evaluation and feedback provided according to users’ response in most Web courseware systems, however, are simple texts showing only whether correct or wrong, correct answers, relevant information, etc., far deviated from actual context. Thus such a system may weaken the corrective function of feedback and, as a result, reduce learners’ understanding of contents and the possibility of leaming transfer. In addition, according to the learning theory of constructivism, learning is influenced by the situation, in which it happens, and knowledge is learned and transferred differently depending on the context in which it is learned. In the background, this study designed and implemented a contextual error-correction feedback system that can provide feedback in a context closely related and similar to the relevant situation according to the response of learners when formative evaluation is carried out in Web courseware. In addition, it applied ‘correction/correct-answer-providing feedback’, ‘relevant information providing feedback’ and ‘contextual error-correction feedback’ to Web courseware for learning actual productivity S/W and verified if ‘contextual error-correction feedback’ is more effective than other two types of feedback for learners’ academic achievement.
알루미늄과 헤테로폴리산으로 개질된 메조포러스 실리카 상에서의 AKD 합성
김현국,우창수,최재석,박민태,이병민,이호인 한국공업화학회 2003 응용화학 Vol.7 No.1
AKD(alkyl ketene dimer) used widely as a neutral sizing agent is produced industrially by halogenization of stearic acid followed by dimerization of alkyl ketene. In the present work, to suppress the byproduct of hydrochloric acid and to improve reaction pathway. AKD was prepared through of ketene intermediate by dehydration of stearic acid in gas phase using reaction with silanol on silica as active sites of the catalyst SBA-15 showed the highest activity due to the large and open tubular pores. It was found that main products were dimer and trimer. Our goal of the present work was to increase of the selectivity for the dimer.
저혈청 배지에서 인간 전골수세포(HL-60)를 이용한 tPA 생산과 세포사멸기작에 관한 연구
김현구,성기돈,김태호,안주희,함문선,박진서,이현용 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.1
tPA 생산과 세포 사멸의 연구를 하기 위해서 인간 전골수세포가 배양되었다. 연속 관류 배양하에서 최대 tPA 생산량은 324 ng/ml이며 최대 세포 농도는 5.27×10 exp (6) cells/ml였다. Phorbol ester를 넣었을 때 tPA 생산량은 420 ng/ml까지 향상되었다. 형광 현미경으로 관찰했을 때, apoptosis는 세포 배양 초기부터 중반까지 우세했고 빠른 교반 속도에서도 우세했다. 그러나 necrosis는 세포배양 말기와 동결된 세포가 해동 되었을 때 우세했다. HL-60 was cultivated to produce tPA (tissue-type plasminogen activator) and study the mechanism of cell death. Maximum cell density and tPA production were obtained as 5.27×10 exp (6) cells/ml and 324 ng/ml, respectively under perfusion cultivation. tPA production was enhanced to 420 ng/ml in adding 160 nM of phorbol ester. The cells were gradually differentiated to granulocytes rather than proliferation. By Fluorescent microscope, apoptosis was prevailed except the death phase and in high agitation speed, but necrosis was prevailed in thawed cells and during the latter periods of the cultivation. It was also proved that tPA was most produced in apoptosis. To obtain higher tPA productivity, the cells must be maintained in apoptosis, not necrosis phase when the cells were dying.