사례보고 : 하수오 복용 후 발생한 재발성 독성 간염 1예

배상훈 ( Sang Hoon Bae ),김동현 ( Dong Hyun Kim ),배영석 ( Young Seok Bae ),이광재 ( Kwang Jae Lee ),김동완 ( Dong Wan Kim ),윤정빈 ( Jeoung Bin Yoon ),홍준호 ( Joon Ho Hong ),김상현 ( Sang Hyun Kim ) 대한간학회 2010 Clinical and Molecular Hepatology(대한간학회지) Vol.16 No.2

Toxic hepatitis has been reported as a major cause of acute hepatitis, but its potential induction by herbal remedies and/or health foods is usually neglected. We experienced a case of toxic hepatitis associated with Polygoni multiflori, a Chinese herb commonly known as Ho-Shou-Wu. A 54-year-old woman consumed Ho-Shou-Wu for 1 month, after which she experienced fatigue and overall weakness. A diagnosis of toxic hepatitis was made based on her clinical history, the findings for viral markers and other laboratory data, and ultrasonography. Her condition improved considerably after she stopped taking Ho-Shou-Wu. However, she resumed taking Ho-Shou-Wu immediately after discharge from hospital, which aggravated her symptoms and liver function. She was immediately readmitted and stopped taking Ho-Shou-Wu. Her relapse into hepatitis immediate after resuming consumption of the herb is strongly indicative of the validity of Koch`s postulate in this case.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

지반과 앵커체의 탄성계수비 (E_(a)/E_(r))에 따른 앵커체 표면에서의 응력전이에 관한 수치해석

홍석우,임종철,고호성 부산대학교 1999 生産技術硏究所論文集 Vol.56 No.-

Anchor is used for a restraining of a ground deformation in the retaining wall, slope-stability et ect. When pullout load is applied to the anchor in the ground, the behavior of the anchor in the ground is differed by the rigidity of anchor body and ground. In this study, the stress-behavior is analyzed by the numerical a analysis on the surface of an anchor body according to the pullout of an anchor. Mostly, The analysis is focused on the change of a shear stress according to the coefficient ratio of elasticity. The coefficient ratio of elasticity(E_(a)/E_(r)) is defined by the ratio between elastic modulus of ground(E_(r)) and that of anchor body (E_(a)). By using this ratio, the progressive failure of anchor body can be analysed. 앵커는 흙막이 벽, 사면안정 등에서 사용되는 지반변형 억제공법이다. 앵커가 지중에서 인발하중을 받으면 앵커체의 강성과 지반의 강성에 따라 각각 다른거동을 하게 된다. 본 논문에서는 인장형 및 압축형 앵커의 인발에 따른 표면에서의 응력거동을, 주로 탄성계수비에 따른 전단응력의 변화에 중점을 두고 수치해석 기법을 이용하여 분석하였다. 여기서, 탄성계수비(coefficient ratio of elasticity)란 지반탄성계수(E_(r))와 앵커체탄성계수(E_(a))의 비 (E_(a)/E_(r))를 말하는데, 이 탄성계수비에 의해 앵커의 진행성 파괴에 대한 영향을 평가할 수 있다.

한국형 후각검사 KVSS Test의 개발

홍석찬,유영석,김은서,김석천,박수홍,김진국,강성호 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.7

회계정보의 질적 속성에 대한 이용자들의 인식변화

홍순복,심호석 한국세무회계학회 2004 세무회계연구 Vol.14 No.-

본 연구는 자본시장에서 회계정보의 수요자라 할 수 있는 재무분석가들과 개인투자자들을 대상으로 외환위기를 전후하여 회계정보의 질적 속성에 대한 인식의 변화를 분석하는 것을 목적으로 하였다. 따라서 외환위기를 전후하여 회계정보의 목적적합성, 신뢰성, 그리고 회계정보이용에 대한 만족도에 있어서 차이가 있는지 조사하고, 회계보고서에 대한 중요성, 회계정보이용의 장애요인과 개설방안 등을 조사하였다. 검증결과 투자자들은 회계정보의 질적 속성에 있어서 목적적합성과 신뢰성이 외환위기이후가 이전보다 향상된 것으로 인식하고 있었으며, 그 결과 회계정보이용에 대한 만족도가 증가된 것으로 나타났다. 회계정보의 종류에 대해서는 손익계산서와 현금흐름표를 중요한 정보로 인식되고 있었고, 정보이용의 장애요인으로는 소문과 루머에 의한 주가의 변화와 회계정보의 비일관성인 것으로 나타났다. 따라서 회계정보에 대한 수요를 증가시키기 위해서는 일관된 회계정책과 회계정보의 질을 증가시키는 것이라고 판단된다. This paper tries to test the recognition change of accounting information demanders about the qualitative characteristics of accounting information before and after IMF. In addition, We try to examine user's recognition about which financial statements has most importantly been considered and the problems and improvements respondents think. According to the results, there has been the recognition change of information demanders about the qualitative characteristics of accounting information. Specifically, the recognition of accounting information quality(relevance and reliability) has been improved and the satisfaction of its use has increased after IMF. The institutional arrangement of accounting and consistent accounting policy appeared as the most important factors in order to overcome the problems at the time of accounting information use.

탄소성 변형을 받는 냉간 압연강의 X선 잔류응력 특성에 관한 연구

홍순혁,이동우,양광호,조석수,주원식 동아대학교 생산기술연구소 2000 生産技術硏究所硏究論文集 Vol.5 No.1

In textured material, diffraction angle 2θ usually shows a nonlinear relation against sin^2Ψ due to elastic anisotropy of crystals. SPHD and SPCD steel is cold-rolled carbon steel for automobile. The characteristics X-ray for stress measurement is Cr K_α and Mo K_α1characteristic X-ray. The sin^2Ψ-2θ diagram under elastic strain seems to have a linear behavior using regression line of data but has a nonlinear behavior in distribution of data by Cr K_αcharacteristic X-ray. As the plastic strain of specimen increases, the nonlinearity of 2θ with respect to sin^2Ψ increases remarkably. On the other hand, the diffraction angle 2 θ by Mo K_α1 characteristic X-ray shows a good linearity on sin^2Ψ-2θ diagram under plastic strain as well as elastic strain. Therefore, This paper presents the measurement of residual stress in cold-rolled carbon steel for automobile using penetration depth of Mo K_α1 charateristic X-ray and multiplicity factor of crystal diffraction plane.

전두-사골동 점액낭종의 비내시경 수술 치험 1례

홍석찬,김진국,강성호 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Frontoethmoidal sinus mucocele usually presents with frontal headache, exophthalmos and diplopia. Over the years it has necessitated either a conservative or a radical procedure. However, recently endoscopic sinus surgery has afforded to decrease the operative morbidity, and image the sinus postoperatively without problem. We have experienced a case of frontoethmoidal sinus mucocele which was satisfactorily treated with endoscopic marsupialization. Till now, no disease recurrence has been noted with endoscopic follow-up for 5 months. The etiology, characteristic features, and treatment of frontoethmoidal mucocele were reviewed.

소아에서 발생한 골수이형성 증후군 2례

홍성진,윤석중,김성우,조형구,오명호,김기혁,이인성 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Myelodysplastic syndrome(MDS) is a group of acquired conditions characterized by progressive bone marrow failure associated with normocellular or hypercellular bone marrow that cannot be attributed to nutritional deficiency, chronic infection, or other chronic systemic illness, and cannot be reversed by the successful treatment of those conditions. Whereas the cases of secondary MDS occur at all ages, primary MDS is essentially a disease of elderly, though no age group is exempt and predomonant in men. The MDS is fundamentally clonal disorders at the level of the haemopoietic totipotent stem cell. Clinically, they are characterized by varing degrees of peripheral cytopenia(s) with morphological and functional abnormalities of blood elements. We have experienced two unrelated pediatric cases, who showed pancytopenia on admission and the characteristic marrow findings of MDS. The first case, a 12 months-old girl, showed increased reticulin with abnormal localization of immature precursor cells(ALIP) in her bone marrow, in addition to dysplastic features such as bi-and multi-nucleation of late normoblasts and internuclear bridging. She also showed 22% of blasts in her bone marrow cells thus classified in the category of RAEB-t after FAB classification. Also found were a chromosomal abnormality namely 46 XX t(14q21q), which was an unusual one. Her family brought her home and, 4 month later, she deceased. The second case, a 12 year-old boy, showed pancytopenia with Pseudo-Pelger-Huet anomaly in neutrophils but no blasts in the peripheral blood. Bone marrow of this case also showed the picture of dyserythropoiesis with binuclearity, internuclear bridging, nuclear fragments, multinuclearity of late normoblasts, in addition to megaloblastoid change in the normoblasts and increased mitosis in granulocytic series. No chromosomal abnormality was found. Classified as RA after FAB classification of MDS. Showed good response to conservative management for anemia for more than one year.

중이 수술후 청력 변화에 대한 임상적 고찰

홍석찬,강성호,이광희 건국대학교 의과학연구소 1994 건국의과학학술지 Vol.4 No.-

statistical analysis of bone conduction loss in chronic otitis media has not been exactly reported until now. Authors studied the relationship between the preoperative bone conduction hearing level and age, nature of middle ear and temporal bone pathology, pneumatization of mastoid in 97 ears of chronic uppurative otitis media performed middle ear surgery at Konkuk University Hospital from March 1992 to December 1992. The results were as following: The mean bone conduction threshold was 16.2±12.4dB. In the cases of ossicular defect, bone conduction loss was greater in total destruction than in partial destruction with statistical significance. Among ossicular defect, incus destruction group showed more bone conduction loss than intact incus group with statistical significance. There was no difference of bone conduction loss according to pathologic findings in middle ear cavity and mastoid antrum, but pathologic groups showed more bone conduction loss than control group with normal temporal bone pneumatization with statistical significance. Comparing pneumatization of mastoid antrum and mastoid process, there was statistically significant bone conduction loss in orders of pneumatic type, diploic type, sclerotic type, cholesteatoma cavity. There was no difference of bone conduction hearing level according to age, sex, and duration of disease process with statistical significance. The results suggest that the bone conduction threshold in chronic otitis media is influenced by artificial elevation due to conductive defect and can be improved by reconstructive surgery.Many patients being followed for chronic suppuration of the middle ear were observed to have sensorineural or mixed type hearing loss. The major cause of this bone conduction loss might be secondary to cochlear biochemical changes occuring through the round window membrane. But, clinical and statistical analysis of bone conduction loss in chronic otitis media has not been exactly reported until now. Authors studied the relationship between the preoperative bone conduction hearing level and age, nature of middle ear and temporal bone pathology, pneumatization of mastoid in 97 ears of chronic suppurative otitis media performed middle ear surgery at Konkuk University Hospital from March 1992 to December 1992. The results were as following: The mean bone conduction threshold was 16.2±12.4dB. Inthe cases of ossicular defect, bone conduction loss was greater in total destruction than in partial destruction with statistical significance. Among ossicular defect, incus destruction group showed more bone conduction loss than intact incus group with statistical significance. There was no difference of bone conduction loss according to pathologic findings in middle ear cavity and mastoid antrum, but pathologic groups showed more bone conduction loss than control group with normal temporal bone pneumatization with statistical significance. Comparing pneumatization of mastoid antrum and mastoid process, there was statistically significant bone conduction loss in orders of pneumatic type, diploic type, sclerotic type, cholesteatoma cavity. There was no difference of bone conduction hearing level according to age, sex, and duration of disease process with statistical significance. The results suggest that the bone conduction threshold in chronic otitis media is influenced by artificial elevation due to conductive defect and can be improved by reconstructive surgery.

한국인 선천성 난청에서 Connexin 26의 분자유전학적 분석

박홍준,박기현,송정환,정영훈,최호석 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.4