Swin Transformer-based multi-scale crowd localization method

Yi Ren,Xin He 한국차세대컴퓨팅학회 2022 한국차세대컴퓨팅학회 학술대회 Vol.2022 No.10

In this paper, we propose a new framework that enables an object detector trained with only point-level annotations to estimate the centroids and sizes of objects in dense scenes. Specifically, the framework is based on the Swin Transformer structure and introduces a self-designed resolution feature fusion module in the hierarchical structure, where the estimation of object centroids is done directly by point supervision, and the object pseudo-size is initialized based on the assumption of local uniform distribution, and the regression of object size is guided by an improved congestion-aware loss function. In the NWPU-Crowd dataset, our method outperformed the existing state-of-the-art detection counting methods in F1-measure, precision, MSE evaluation criteria.

How Do Structural Oil Price Shocks Affect China’s Investor Sentiment? The Critical Role of OPEC Oil Supply Shocks

Yi-Shuai Ren,Yong Jiang,Chao-Qun Ma,Olaf Weber 한국증권학회 2021 Asia-Pacific Journal of Financial Studies Vol.50 No.5

This paper applies a modified structural vector autoregressive (SVAR) model to explore whether explicit structural oil price shocks affect investor sentiment in China’s stock market. The results indicate that China’s investor sentiment responds significantly positively to OPEC supply shocks, while it responds significantly negatively to oil-specific demand shocks. However, China’s stock investor sentiment does not respond to aggregate demand shocks and non-OPEC supply shocks. In addition, OPEC supply shocks and oil-specific demand shocks have greater explanatory power for variations in stock investor sentiment through variance decomposition.

An improved regularized particle fi lter for remaining useful life prediction in nuclear plant electric gate valves

Ren-yi Xu,Hang Wang,Min-jun Peng,Yong-kuo Liu 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.6

Accurate remaining useful life (RUL) prediction for critical components of nuclear power equipment is animportant way to realize aging management of nuclear power equipment. The electric gate valve is oneof the most safety-critical and widely distributed mechanical equipment in nuclear power installations. However, the electric gate valve's extended service in nuclear installations causes aging and degradationinduced by crack propagation and leakages. Hence, it is necessary to develop a robust RUL predictionmethod to evaluate its operating state. Although the particle filter(PF) algorithm and its variants can dealwith this nonlinear problem effectively, they suffer from severe particle degeneracy and depletion, whichleads to its sub-optimal performance. In this study, we combined the whale algorithm with regularizedparticle filtering(RPF) to rationalize the particle distribution before resampling, so as to solve theproblem of particle degradation, and for valve RUL prediction. The valve's crack propagation is studiedusing the RPF approach, which takes the Paris Law as a condition function. The crack growth is observedand updated using the root-mean-square (RMS) signal collected from the acoustic emission sensor. Atthe same time, the proposed method is compared with other optimization algorithms, such as particleswarm optimization algorithm, and verified by the realistic valve aging experimental data. The conclusion shows that the proposed method can effectively predict and analyze the typical valve degradationpatterns

Exploring the Key Genes and Pathways of Osteoarthritis in Knee Cartilage in a Rat Model Using Gene Expression Profiling

Yi-Ming Ren,Xin Zhao,Tao Yang,Yuan-Hui Duan,Yun-Bo Sun,Wen-Jun Zhao,Meng-Qiang Tian 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.6

Purpose: To compare differentially expressed genes (DEGs) mediating osteoarthritis (OA) in knee cartilage and in normal kneecartilage in a rat model of OA and to identify their impact on molecular pathways associated with OA. Materials and Methods: A gene expression profile was downloaded from the Gene Expression Omnibus database. Analysis ofDEGs was carried out using GEO2R. Enrichment analyses were performed on the Gene Ontology (GO) and Kyoto Encyclopedia ofGenes and Genomes pathway using the Search Tool for the Retrieval of Interacting Genes database (http://www.string-db.org/). Subsequently, the regulatory interaction network of OA-associated genes was visualized using Cytoscape software (version 3.4.0;www.cytoscape.org). Results: In the gene expression profile GSE103416, a total of 99 DEGs were identified. Among them, 76 DEGs (76.77%) were overexpressed,and the remaining 23 DEGs (23.23%) were underexpressed. GO and pathway enrichment analyses of target geneswere performed. Using gene-gene interaction network analysis, relevant core genes, including MET, UBB, GNAI3, and GNA13,were shown to hold a potential relationship with the development of OA in cartilage. Using quantitative real-time PCR, the Gna13/cGMP-PKG signaling pathway was identified as a potential research target for therapy and for further understanding the developmentof OA. Conclusion: The results of the present study provide a comprehensive understanding of the roles of DEGs in knee cartilage in relationto the development of OA.

Effect of Monocyte Chemotactic Protein-1 on Osteoprotegerin Gene Expression

Ren, Yi,Wise, Gary E. Korean Academy of Oral Biology and the UCLA Dental 2003 International Journal of Oral Biology Vol.28 No.1

Tooth eruption requires the recruitment of mononuclear cells (osteoclast precursors) into the dental follicle where they fuse to form osteoclasts that resorb the alveolar bone for tooth eruption. In the rat first mandibular molar, the dental follicle expresses the monocyte chemotactic protein-1 (MCP-1) gene at the time of maximal influx of mononuclear cells into the follicle, day 3 postnatally. At this time, the expression of the osteoprotegerin (OPG) gene also is reduced such that osteoclast formation would not be inhibited. Thus, at day 3, a maximal number of osteoclasts are seen on the alveolar bone surrounding the unerupted tooth. In this study, we wished to determine if MCP-1, in addition to its potential chemotactic role, also contributed to the decrease in the gene expression of OPG in cultured dental follicle cells. The results showed that indeed NCP-1 reduced OPG gene expression in both a time-and dosage-dependent manner with maximal inhibition at 3 hrs at a concentration of 10 ng/ml. Immunostaining showed that MCP-1 reduced the protein levels of OPG in the cultured cells. Thus MCP-1 is another molecule produced by the dental follicle that may inhibit OPG gene expression at a critical time to enable osteoclast formation to occur for tooth eruption.

Present Situations and Future Prospects of Sericulture in China

(Yi Ren Li) 한국잠사학회 2000 한국잠사학회 잠사과학 100주년 국제심포지엄 및 추계학술대회 Vol.- No.-

Advanced Parameter Identification for a Linear-Motor-Driven Motion System Using Disturbance Observer

Yi-Ren Pan,An-Chen Lee,Yi-Ti Shih,Rong-Hwang Horng 한국정밀공학회 2009 International Journal of Precision Engineering and Vol. No.

Disturbance observer (DOB) is generally introduced into motion control systems to eliminate undesired disturbances and plant uncertainty. The DOB is also used for system identification. This work presents a novel experimental identification algorithm using disturbance observer to identify inertia, viscous coefficient, and friction of linear-motor-driven motion system. A conventionally adopted algorithm for determining the inertia of the motion system based on orthogonal relations among system responses is modified and extended to estimate the viscous coefficient and the magnitude of Coulomb friction of the underlying system. The advantages of the proposed method are high convergence rate and only one experiment needed to evaluate the system parameters. The proposed algorithm is demonstrated to be workable by both simulation and experiment.

Mechanical Properties and Energy Absorption of Soft–Hard Dual Phase Lattice Structures Manufactured via Selective Laser Melting

Yi Ren,Yu Nie,Wei Ran,Zhuofan Liu,Lixia Wang,Chao Lou,Wei Chen 대한금속·재료학회 2024 METALS AND MATERIALS International Vol.30 No.2

Lattice structures with excellent mechanical performance can be achieved through delicate design. In this work, inspired bythe soft–hard multiphase crystals, three types of dual phase lattice structures (DPLS) composed of body-centered cubic withZ-struts (BCCZ) matrix phase and face and body-centered cubic with Z-struts (FBCCZ) reinforcement phase were designedand fabricated by selective laser melting (SLM) using 316L stainless steel powder. Quasi-static compression experimentand numerical simulation were carried out to investigate their mechanical properties, energy absorption and deformationbehavior. The results showed that the mechanical properties of all DPLS samples were higher than that of single phaseBCCZ lattice structure. The four-body diagonal DPLS sample exhibited the highest specific strength and specific stiffness,which was 9.0% and 14.2% higher than single phase BCCZ lattice structure; while, the two-face diagonal DPLS sample hadthe highest specific energy absorption value of 17.45 J/g. Besides, the experimental and simulated results revealed that thearrangements and volume fraction of reinforcement phase had a significant impact on the performance, deformation behaviorand internal stress distribution of the DPLS samples during compressive deformation.

Development of a Serum-Free Culture Method for Endothelial Cells of the Stria Vascularis and Their Pro-inflammatory Secretome Changes Induced by Oxidative Stress

Ying Yi,Shu-Bin Fang,Guan-Xia Xiong,Xian-Ren Wang,Hui-Ting Chen,Wan-Yi Huang,Li-Xuan Feng 대한이비인후과학회 2023 Clinical and Experimental Otorhinolaryngology Vol.16 No.1

Objectives. Reactive oxygen species in the stria vascularis (SV) of the cochlea may be involved in the pathogenesis of sen-sorineural hearing loss. However, the effects of oxidative stress on SV endothelial cells (SV-ECs) remain largely un-known, and no feasible in vitro cell culture model exists for the functional study of SV-ECs. Methods. We isolated primary SV-ECs from the SV of neonatal mice. The apoptosis-reducing effects of fibronectin in SV-ECs cultured with serum-free medium were determined using β-galactosidase staining and flow cytometry. SV-ECsincubated in serum-free medium were treated with various H2O2 concentrations to evaluate the effects of H2O2 ontheir viability. The secretome of SV-ECs treated with or without H2O2 (100 μM or 500 μM) was analyzed using high-resolution mass spectrometry. The function of the SV-EC secretome was evaluated by a macrophage assay. Results. We successfully isolated and characterized the SV-ECs. Treatment with H2O2 at concentrations up to 500 μM for2 hours and further incubation with serum-free medium in plates precoated with fibronectin showed no significanteffect on apoptosis. Compared to the control SV-ECs, the amount of differential proteins in the secretome of SV-ECsstimulated with 500 μM H2O2 was much higher than in those treated with 100 μM H2O2. Kyoto Encyclopedia ofGenes and Genomes and Gene Ontology analyses suggested that the proteins differentially expressed in SV-ECstreated with 500 μM H2O2 were involved in the regulation of multiple signaling pathways and cellular processes. Thesecretome of H2O2-stimulated SV-ECs exhibited significant pro-inflammatory effects on macrophages. Conclusion. We successfully established an in vitro serum-free culture method, identified the differential proteins releasedby oxidative stress-induced ECs and their functions, and revealed the pro-inflammatory effects of the secretome ofH2O2-stimulated SV-ECs. Therefore, SV-ECs might elicit immunoregulatory effects on bystander cells in the microen-vironment of oxidative stress-induced cochlea, especially cochlear macrophages.

Provably Secure Aggregate Signcryption Scheme

Xun-Yi Ren,Zheng-Hua Qi,Yang Geng 한국전자통신연구원 2012 ETRI Journal Vol.34 No.3

An aggregate signature scheme is a digital signature scheme that allows aggregation of n distinct signatures by n distinct users on n distinct messages. In this paper, we present an aggregate signcryption scheme (ASC) that is useful for reducing the size of certification chains (by aggregating all signatures in the chain) and for reducing message size in secure routing protocols. The new ASC scheme combines identity-based encryption and the aggregation of signatures in a practical way that can simultaneously satisfy the security requirements for confidentiality and authentication. We formally prove the security of the new scheme in a random oracle model with respect to security properties IND-CCA2, AUTH-CMA2,and EUF-CMA.