다입력 계통에 대한 새로운 최적 슬라이딩 모드제어기

박승규,남징락,진미정 國立 昌原大學校 産業技術硏究所 1999 産技硏論文集 Vol.13 No.-

In this paper, a novel sliding surface is proposed by defining a novel virtual state. This sliding surface has nominal dynamics of an original system and makes it possible that the Sliding Mode Control(SMC) technique is used with the various types of controllers. Its design is based on the augmented system of which dynamics have a higher order than that of the original system. The reaching phase is removed by using an initial virtual state which makes the initial sliding function equal to zero.

결핵성 흉막염 환자에서 폐실질 결핵의 동반 유무에 따른 임상적 특성

이기만, 최강현, 안진영, 정혜원, 김미경, 김성진 충북대학교 의과대학 충북대학교 의학연구소 2012 忠北醫大學術誌 Vol.22 No.1

연구목적; 결핵성 흉막염의 발생과 관련된 인자를 알아보고자하였으며, 방사선학적 소견으로 분류된 일차성 혹은 재활성화에 의한 병변에 따라 양 군 간의 임상적 자료를 비교 분석하고자 하였다. 연구대상 및 방법; 2010년부터 2011년까지 충북대학교병원에 내원하여 결핵성 흉막염으로 진단된 18세 이상의 모든 환자를 대상으로, 폐실질 결핵의 동반양상을 분석하여 활동성여부 및 재활성화 결핵 여부로 나눈 후 각 군 간의 방사선학적 특성, 흉수소견, 기저질환 및 임상적 특성을 비교하였다. 결과; 결핵성 흉막염으로 진단된 대상 환자 37명 중 폐실질 혹은 임파선에 활동성 혹은 비활동성 결핵 소견을 동반한 경우는 27명(27/37, 73%)이고, 활동성 폐실질 결핵의 소견을 동반한 경우는 16명 (43%)이었다. 방사선학적 분석으로 재활성화의 소견을 가진 환자는 18명이고(49%)이고 일차성 결핵 성 흉막염이 발생한 경우로 분석된 환자는 19명(51%)이었다. 재활성화의 경우는 일차성 결핵 환자에 비해 평균나이가 많고(64.6세 및 41.5세, p<0.002) 동반질환 빈도가 높으며(50% 및 5 %, p<0.003), 말초혈액에서의 혈색소치 평균 또한 의미있게 낮았다(11.75 g/dL 및 13.40 g/dL, p<0.014). 결론; 결핵의 재활성화에 의한 결핵성 흉막염은 일차성 결핵 흉막염보다 고령환자 및 면역 저하와 관 련된 동반질환이 있는 경우가 많으며, 빈혈을 동반하는 경우가 많았다.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

Changes in Quality Characteristics of Pork Patties Containing Antioxidative Fish Skin Peptide or Fish Skin Peptideloaded Nanoliposomes during Refrigerated Storage

Jing-Jing Bai,Jung-Gyu Lee,Sang-Yoon Lee,Soojin Kim,Mi-Jung Choi,Youngjae Cho 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.5

Marine fish skin peptides (FSP) have been widely studied due to their antioxidant and antimicrobial properties. We aimed to use a natural antioxidant, FSP, to replacing synthetic preservatives in a pork patty model, which is safer for human body. Moreover, nano-liposome technology can be applied for masking the fishy smell and improving the stability of this peptide. Therefore, in this study, the effects of FSP and FSP-loaded liposomes (FSPL) on pork patty were evaluated through the tests of thiobarbituric acid reactive substances (TBARS), color, cooking loss, texture, volatile basic nitrogen (VBN), and the pH value, during 14 d of refrigerated (4°C) storage. The results showed that all FSP-treated patties had lower TBARS values than control patties, which indicated an inhibitory effect of FSP on lipid oxidation. This effect in the patties depended on the FSP concentration. However, FSPL-treated patties showed significantly higher and undesirable TBARS values compared to the control, and this effect depended on the FSPL concentration. None of the physicochemical results showed remarkable changes except the pH and VBN values. Therefore, this study provides evidence that FSP has great potential to inhibit the lipid oxidation of pork patties and is capable of maintaining the quality and extending the shelf life. However, it is necessary to study the application of FSP treatments greater than 3% to improve the antioxidant effect on pork patties and search for other coating materials and technology to reduce the drawbacks of FSP.

Effects of higenamine and its 1-naphthyl analogs, YS-49 and YS-51, on platelet TXA₂ synthesis and aggregation

Pyo, Mi Kyung,Kim, Jeong Mi,Jin, Jing-Ling,Chang, Ki Churl,Lee, Duck Hyung,Yun-Choi, Hye Sook Pergamon Press 2007 Thrombosis research Vol.120 No.1

<P><B>Abstract</B></P><P>The effects of higenamine and its 1-naphthyl analogs, YS-49 and YS-51, on thromboxane A<SUB>2</SUB> (TXA<SUB>2</SUB>) formation from arachidonic acid (AA) and aggregation in platelets, were investigated. YS-49 and YS-51 (IC<SUB>50</SUB>; 32.8 and 39.4?μM respectively) exhibited much stronger inhibitory effects on TXA<SUB>2</SUB> formation than higenamine (IC<SUB>50</SUB>; 2.99?mM). The higher inhibitory potencies of YS-49 and YS-51 (IC<SUB>50</SUB>: 3.3 and 5.7?μM respectively) than higenamine (IC<SUB>50</SUB>: 140?μM) on AA induced rat platelet aggregation was presumed to be the result of low inhibitory effect of higenamine than YS-49 and YS-51 on TXA<SUB>2</SUB> production from AA. Among the present three compounds, the more hydrophobic naphthylmethyl groups were supposed to be more favorable than <I>p</I>-hydroxybenzyl moiety, at 1-position of the tetrahydroisoquinoline ring, to display the inhibitory effects on TXA<SUB>2</SUB> production and AA induced aggregation of platelets. In addition, higenamine, YS-49 and YS-51 were observed directly antagonistic on TXA<SUB>2</SUB> receptor (TP receptors) by displaying inhibitory effects to U46619 (TXA<SUB>2</SUB> mimetic) induced platelet aggregation, however all of the three compounds showed similar order of inhibitory potencies. The present results are suggestive that YS-49 and YS-51 exert their inhibitory effects on AA-induced platelet aggregation partly by inhibiting the production of TXA<SUB>2</SUB> from AA and partly by directly blocking the TP receptor, in addition to the previously reported effects on α<SUB>2</SUB>-adrenergic receptor. On the other hand, higenamine is supposed to antagonize AA-induced platelet aggregation by mostly directly blocking the TP receptor.</P>

중국어 교육에서 단어 간 공백이 한국인 학습자의 낭독에 미치는 효과

한미애(Han Mi-Ae)(韓美愛),서정정(Xu, Jing-Jing)(徐晶晶),강신(Jiang, Xin)(江新) 대한중국학회 2019 중국학 Vol.68 No.-

The inter-word space is an important visual cue in Korean reading comprehension, which could improve both the efficiency of silent reading and the processing of oral reading. However, there’s no inter-word space in Chinese text as the boundary of words. This study discussed whether the inter-word space would affect the oral fluency and accuracy, and whether the effect would change with the Chinese proficiency. The experiment was a 2 (text type: no inter-word space text, text with inter-word spaces) × 2 (Chinese proficiency: beginner level of Korean learners, intermediate level of Korean learners, Chinese native speakers) mixed design. The participants were required to read the Chinese sentences with or without inter-word spaces loudly, and the sound were recorded with Cool Edit Pro software. The results showed: (1) the inter-word space didn’t affect the oral fluency of Chinese; (2) the inter-word space could improve the learners’ awareness of word boundary; (3) for the Korean Chinese learners, the less familiar with the Chinese word recognition, the less salience of the inter-word space effect on oral accuracy. 한국어 문장에 존재하는 공백은 독자가 문장 혹은 단락을 이해하는 아주 중요한 시각적 단서로, 묵독뿐만 아니라 낭독에도 매우 중요한 역할을 한다. 이와 반대로 중국어 문장에는 단어 경계를 나타내는 공백이 존재하지 않는다. 본 연구는 단어 간 공백이 낭독 유창성과 정확성에 어떠한 영향을 미치는지, 그 영향은 중국어 수준에 따라 다르게 나타나는지 고찰하였다. 실험은 2(제시 방식: 공백 무삽입, 공백 삽입) X 3(중국어 수준: 초급·중급 학습자, 모국어 화자) 이원혼합설계로 진행되었다. 참가자들에게 두 가지 제시 방식의 중국어 문장을 낭독하도록 요청하고, Cool Edit Pro 프로그램을 사용해 그 소리를 녹음하였다. 실험 결과, (1) 단어 간 공백은 참가자들의 낭독 유창성에 아무런 영향을 미치지 않았다. (2) 단어 간 공백은 한국인 학습자들의 단어 경계 인식을 제고시켰다. (3) 글자와 단어 식별이 익숙하지 않은 초급 학습자일수록 낭독 정확성에 대한 공백 효과가 뚜렷하게 나타나지 않았다.

β-Agarase Gene from a Marine Bacterium, Pseudoalteromonas sp. JT-6: Cloning, Expression and Enzymatic Properties

Jing Wu,Hyun-Mi Dae,Hwa-Young Kwon,Na-Ri Song,Kyoung-Sook Kim,Young-Choon Lee 한국생명과학회 2008 한국생명과학회 심포지움 Vol.49 No.-

Rapid Melt Polycondensation of L-Lactic Acid under Microwave Irradiation

Jing Shu,Peng Wang,Ying Min Zhang,Xiao Juan Mi 한국고분자학회 2006 Macromolecular Research Vol.14 No.6

Ethylcellulose microparticles containing chitosan and gelatin: pH-dependent release caused by complex coacervation

Mi Kyoung Kang,Jing Dai,김진철 한국공업화학회 2012 Journal of Industrial and Engineering Chemistry Vol.18 No.1

Ethylcellulose microparticles containing chitosan and gelatin were prepared by spray drying water-in-oil (W/O) emulsion. Water phase was chitosan:gelatin solution in distilled water, and oil phase was ethylcellulose solution in dichloromethane. FITC-dextran was included in water phase as a fluorescence dye. The maximum coacervation was observed at pH 6.0 when the ratio of chitosan to gelatin was 1:15. Microparticles containing chitosan and gelatin in the ratio showed a higher release under acidic condition (e.g. pH 4.0) and neutral condition (e.g. pH 7.0), but a lower release at pH 5.0 and pH 6.0. The complex coacervate composed of chitosan and gelatin was efficiently formed at those pHs, and the formation of coacervate would be responsible for the lower release.

Anti-obesity Effects of Sparassis crispa on High-fat Diet-induced Obese Mice

Mi Ra Lee(이미라),Jing Gang Hou(하지강),Shahnaz Begum(샤나즈베검),Yun Bo Wang(왕운보),Deuk Sil Oh(오득실),An Jin Wi(위안진),Byung Sun Yoon(윤병선),Chang Keun Sung(성창근) 한국생명과학회 2014 생명과학회지 Vol.24 No.9

본 연구는 고지방식이로 유도한 비만 흰쥐에 대한 꽃송이 버섯의 항비만 효과를 관찰하였다. 6주령 수컷C57BL/6 마우스를 이용하여 칼로리의 45%를 지방으로 구성한 고지방식이를 이용하여 비만을 유도하였으며, 대조군은 정상식이를 제공하였다. 처리군은 고지방 식이에 꽃송이 버섯 분말을 1%, 3%, 5% 수준으로 첨가하여 12주간 제공하였다. 체중, 식이섭취, 장기무게, 내장지방, 혈청지질, 변무게 및 변지방, 간지방, 조직병리실험을 실시하였다. 고지방식이 섭취군은 체중, 식이섭취, 피하지방 및 복막하지방, 혈청 콜레스테롤 및 중성지방농도, 변지방, 간지방, 부고환지방 조직의 지방세포 크기가 증가하였다. 그러나 고지방식이에 꽃송이 버섯 분말을 첨가한 실험군에서는 체중증가, 식이섭취 및 식이효율, 간 콜레스테롤 함량, 내장지방 무게가 꽃송이 버섯 첨가량에 따라 감소하였다. 특히, 5% 꽃송이버섯 첨가군은 간세포의 지방축적과 지방간 현상이 현저히 개선되었으며, 부고환 지방조직에서의 지방세포 크기도 현저히 감소하였다. 본 연구결과를 통하여 볼 때, 꽃송이 버섯은 뛰어난 항비만 효과를 가지고 있어, 비만 조절을 위한 기능성 식품으로의 이용이 가능할 것으로 사료된다. The present study investigated the anti-obesity effects of Sparassis crispa (SC) on mice fed a high-fat (HF, 45 kcal% fat) diet. Mice were fed either a normal control diet and an HF diet or an HF diet supplemented with SC (1%, 3%, and 5%) for 12 weeks. The consumption of an HF diet compared to the NC group resulted in increases in body weight, the food efficiency ratio (FER), retroperitoneal and subcutaneous fat weights, cholesterol and triglyceride levels, fecal fat, and liver lipids. However, the administration of SC significantly decreased body weight gain, food intake, FER, cholesterol and triglyceride levels, and liver lipids in a dose-dependent manner. In particular, treatment with 5% SC significantly reduced the occurrence of fatty liver deposits and steatosis, which are associated with the increased adipocyte size in mice fed an HF diet. Therefore, these results suggested that dietary supplementation with SC exerts anti-obesity effects and could be used as a functional food to control obesity.