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      • KCI등재

        초음파 측정에 의한 한우의 도체육량 예측

        이용준,전기준,최성복,석홍기,김석중,이성기,송영한 한국동물자원과학회 2003 한국축산학회지 Vol.45 No.2

        본 시험은 초음파를 이용한 한우의 도체육량등급 예측율을 향상시키기 위하여 24개월령 거세한우 573두를 대상으로 출하직전에 체중측정과 함께 실시간 초음파 진단기를 이용하여 도형체질을 측정하였다. 초음파 측정치와 도체실측치와의 비교분석에서 도출된 다양한 육량예측 기법을 이용하여 도체육량등급을 예측하였고, 그 결과를 요약하면 다음과 같다. 등지방 두께와 배최장근 단면적의 도체 실측치와 초음파 측정치간의 차이는 각각 0.6±1.65mm와 0.7±5.56㎡로 나타났다. 등지방 두께 및 배최장근 단면적의 초음파 측정치와 도체 실측치간의 상관계수는 각각 0.86 및 0.82로 높게 나타났다(p<0.001). 도체육량등급 예측율은 육량지수 산식, 등지방 보정식, 중회귀 분석 및 의사결정나무 분석에서 각각 80.3%, 81.3%, 80.1% 및 81.8%를 보여, 의사결정나무 분석이 예측율과 활용성이 가장 높은 것으로 나타났다. This study was conducted to predict the carcass yield traits using ultrasound before slaughter and to enhance the prediction accuracy of carcass yield grade by applying various strategies. For this experiment, five hundred seventy three Hanwoo steers of 24 months of age were used. Difference between ultrasound results and carcass measure of BFT and LMA was 0.6±1.65㎜ and 0.7±5.56㎤, respectively. Correlation coefficient between ultrasound result and carcass measure of BFT and LMA was 0.86 and 0.82 respectively (p<0.001). Results for improving predictions of yield grade by four methods0the Korean yield grade index equation, fat depth alone, regression and decision tree methods were 80.3%, 81.3% 80.1% and 81.8%, respectively. We conclude that the decision tree method can easily predict yield grade and is also useful for increasing prediction accuracy rate.

      • KCI등재
      • KCI우수등재

        한우 미경산우에 대한 난소적출이 발육 및 도체형질에 미치는 영향

        원유석,박노형,정준,정재경,임연수,박종관,이문걸 한국축산학회 1999 한국축산학회지 Vol.41 No.5

        Five intact control(IC) and 5 ovariectomized heifers(OVX), born in the Livestock Improvement Main Center of National Livestock Co-operatives Federation, were used to study the effects of ovariectomy on growth and carcass traits. Ovariectomy was performed surgically at an average of 6 months old via an incision through the left lumbar fossa area. All heifers were fed concentrates and rice straw based on NLCF's feeding program. Heifers were slaughtered at an average of 24 months old and carcass traits were investigated according to the standard of the Animal Product Grading Service. Physical traits and chemical contents including fatty acids composition and cholesterol concentration in M. longissimus dorsi muscle were examined. Though feed intakes were not different, average daily gain of OVX was higher about 8.4% than that of IC, resulting in improved feed efficiency. The pH of the strip loin from OVX was higher than that of IC(OVX vs IC : 5.43 vs 5.36, P$lt;0.05), however, lowered in cholesterol content(OVX vs IC : 81.76 vs 89.36). Ovariectomy did not affect on tenderness and cooking loss but water holding capacity of the strip loin was higher than IC. Contents of myristic acid, palmitic acid, palmitoleic acid, stearic acid and oleic acid tended to be decreased by OVX, in contrast, linoleic acid was increased. Meat production index(MPI) and meat quality gade(MQG) were not influenced by ovariectomy. All of the OVX got lst grade in the carcass quality grade. Though an ovariectomy was little beneficial effects to improve the MPI and MQG items, overall meat quality grade of OVX was better than IC.

      • Anti-tumor necrosis factor-alpha treatment reduces allergic responses in an allergic rhinitis mouse model : Anti-allergic effects of a TNF-α inhibitor

        Mo, J.-H.,Kang, E.-K.,Quan, S.-H.,Rhee, C.-S.,Lee, C. H.,Kim, D.-Y. Wiley (Blackwell Publishing) 2011 Allergy Vol.66 No.2

        <P>To cite this article: Mo J-H, Kang E-K, Quan S-H, Rhee C-S, Lee CH, Kim D-Y. Anti-tumor necrosis factor-alpha treatment reduces allergic responses in an allergic rhinitis mouse model. Allergy 2011; 66: 279-286. ABSTRACT: Background:??Tumor necrosis factor (TNF)-관 is a principal mediator of the acute inflammatory response, including allergic rhinitis. TNF-관 inhibitors are widely used for the treatment of inflammatory conditions such as rheumatoid arthritis and inflammatory bowel diseases; however, the effects of TNF-관 inhibitors on allergic rhinitis are not well established. We aimed to investigate the effects of infliximab, a TNF-관 inhibitor, on allergic rhinitis in a mouse model. Methods:??BALB/c mice were sensitized with ovalbumin (OVA) and alum, and challenged intranasally with OVA. The TNF-관 inhibitor, infliximab was administered intraperitoneally, and multiple parameters of allergic responses were evaluated to determine the effects of infliximab. Results:??Infliximab reduced allergic symptoms and eosinophilic infiltration into the nasal mucosa. It also suppressed total and OVA-specific IgE levels, and inhibited local Th2 cytokine transcription in the nasal mucosa and systemic Th2 cytokine production by splenocytes. Furthermore, the expression of E-selectin, neither intercellular adhesion molecule 1 (ICAM-1) nor vascular cell adhesion molecule 1 (VCAM-1), in the nasal mucosa was suppressed in the infliximab-treated group when compared to the nontreated group. Conclusion:??This study shows that the TNF-관 inhibitor infliximab induces anti-allergic effects by decreasing local and systemic Th2 cytokine (IL-4) production, total and OVA-specific IgE levels, adhesion molecule (E-selectin) expression, and eosinophil infiltration into the nasal mucosa in an allergic rhinitis model. Therefore, infliximab should be considered as a potential agent in treating allergic rhinitis.</P>

      • 한국 성인에서 비알콜성 지방간의 중증도에 따른 대사이상의 특징

        김형진,김대중,김수경,김세화,이유미,안철우,차봉수,송영득,임승길,김경래,이현철,허갑범 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.4

        연구배경: 30세 이상의 성인 한국인에서 지방간의 중증도와 대사증후군의 여러 요소들 (특히 인슐린저항성 및 중심성비만)과의 관련성을 분석하고자 하였다. 방법: 대상자는 2001년 4월부터 6월까지 건강검진센터를 방문한 사람들 중 만성 바이러스성 간염이나 일주일에 2회 이상 음주력이 있는 사람들을 제외한 1074명 (남자 502, 여자 572)에서 문진, 신체검사, 채혈 그리고 복부초음파를 시행하였다. 결과: 1074명중 522명에서 지방간이 양성이어서 양성율은 49%였으며 남성은 여성에 비해 높은 유병률을 보였다. (57 vs 42%, p<0.05). 당뇨병, 비만 그리고 이상지질증을 가지지 않은 사람들에서 비알콜성 지방간의 유병률은 20%였다. 지방간이 양성인 522명중 218명은 경도, 273명은 중등도, 31명은 중증의 지방간 소견을 보였다. 체질량지수, 허리둘레, 체지방률, 수축기혈압, aspartate aminotransferase, alanine aminotransferase, 총콜레스테롤, 중성지방, 그리고 총콜레스테롤/고밀도지단백 비는 지방간의 중증도에 따라 의미있게 증가하는 양상을 보였다(p<0.05). 다중회귀분석을 시행하였을 때 지방간의 중증도를 잘 반영하는 인자로는 허리둘레, alanine aminotransferase, HONA_IR, 총콜레스테롤/고밀도지단백비, aspartate aminotransferase, 그리고 수축기혈압의 순서로 나타났다. 공복혈당장애, 고혈압 및 인슐린저항성은 지방간을 가진 군에서 대조군보다 의미있게 높은 빈도를 보였을 뿐만 아니라 지방간의 중증도에 따라 차이를 보였다(p<0.05). 인슐린저항성은 심한 지방간에 비교위험도가 14.7(CI; 6.8∼32.0), 중등도의 지방간에서 6.9(CI; 4.6∼10.3), 경도의 지방간에서 5.7(CI; 3.6∼8.8)이었으며 HOMA_IR의 상위 1/4을 인슐린저항성이 있는 군으로 정의하였을 때 각군에 인슐리저항성을 가진 비율은 7.6, 32.0, 36.0, 그리고 55%였다(p<0.05). 지방간의 중증도에 따른 비알콜성 지방간염의 고위험군 비율은 각각 5.0, 21.6, 27.8, 그리고 58.1%였다(p<0.05). 결론: 우리나라의 비알콜성 지방간의 빈도는 서구인에 비해 높은 것으로 나타났다. 또한 비알콜성 지방간이 있을 경우 대사증후군과 관련된 여러인자들(특히 인슐린저항성과 중심성비만)과 비알콜성 지방간염의 위험이 현저히 증가하며 초음파의 중증도 분류에 따라 비례하였다. Background: We evaluated the frequency of non-alcoholic fatty liver disease, and the associations between the metabolic abnormalities and severity of non-alcoholic fatty liver disease in Korean adults using ultrasonography. Methods: We examined 1074 Korean adults above the age of 30 years, comprising of 502 men and 572 women, participating in medical check-ups at the Health Promotion Center. Hepatitis B and C serologies were negative, and the average weekly alcohol intake was ≤ 2 standard drinks. A standard interview, physical exam and biochemical study, were conducted, and an experienced operator carried out ultrasound liver studies. Results: 522 of the subjects had non-alcoholic fatty liver disease, and the remaining 552 did not. The frequency in the men was higher than that in the women (57 vs 42%, p<0.05). The frequency of non-alcoholic fatty liver disease in the subjects without diabetes, obesity or dyslipidemia was 20%. We classified subjects into 4 groups: the controls (n=552) and those with mild (n=218), moderate (n=273) or severe fatty liver disease (n=31), according to their ultrasonographic findings. BMI, waist circumference, body fat, systolic blood pressure, aspartate aminotransferase, alanine aminotransferase, total cholesterol, triglyceride, the total-to HDL-cholesterol ratio, impaired fasting glucose, hypertension and insulin resistance, were all significantly increase with the increased severity of non-alcoholic fatty liver disease (p<0.05). Following the multiple regression analyses, waist, alanine, aminotransferase, HOMAIR, the total- to HDL-cholesterol ratio, aspartate aminotransferase and systolic blood pressure, were all associated with the severity of non-alcoholic fatty liver disease. Odd ratios of insulin resistance in the mild, moderate and severe non-alcoholic fatty liver disease were 14.7 (CI: 6.8∼32.0), 6.9 (CI: 4.6∼10.3) and 5.7 (CI 3.6∼8.8), respectively. The percentages of subjects with insulin resistance in each group were 7.6, 32.0, 36.0 and 55.0% (p<0.05), respectively. The percentages of subjects with risk of non-alcoholic steatohepatits in each groups were 5.0, 21.6, 27.8 and 581% (p<0.05) respectively. Conclusion: The frequency of non-alcoholic fatty liver disease was relatively high in Korean adults. Proportional differences in metabolic abnormalities, relation to the severity of non-alcoholic fatty liver disease, were found by ultrasonography (J Kor Soc Endocrinol 17:514∼525, 2002).

      • KCI등재

        Local structures of equiatomic CoTi alloy films with various degrees of structural order

        이영백,황정남,J. Y. Rhee,Y. Jeon,Y.V. Kudryavtsev,Y.V. Kudryavtsev 한국물리학회 2003 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.43 No.2

        The microstructures of ordered B2-phase and amorphous-like equiatomic CoTi alloy lms have been investigated by using X-ray absorption spectroscopy. Analysis of the extended X-ray absorption ne structure (EXAFS) data elucidates, at least in a local sense, that both Co and Ti atoms are arranged in an ordered cubic-B2 structure for the lm deposited on a heated substrate (730 K) while the lm deposited on a the substrate cooled down to 150 K is amorphous-like. The lm deposited at 150 K has the same main peak position as the pure Co lm in the Co K-edge Fourier transform EXAFS spectrum. This indicates that the radial distance is the same as for a pure Co film, and re ects the formation of Co clusters, which is attributed to an increase in the number of nearest Co-Co bondings and implies the formation of a considerable amount of antistructure Co atoms (Co atoms at Ti sites) and nearest-neighbor clustering of Co atoms. These results are consistent with recent observations and interpretation of a weakly ferromagnetic behavior in CoTi lms deposited at 150 K [Y. P. Lee et al, Phys. Rev. B 60, 8067 (1999)] and their other peculiar physical properties.

      • KCI등재
      • KCI등재

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