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윤진하 대한신경정신의학회 2020 신경정신의학 Vol.59 No.2
The job is one of the essential elements of human happiness. On the other hand, workers are exposed to many hazardous environments that cause disease. The Occupational Safety and Health Act aims to “maintain and promote the safety and health of those who provide labor,” by “establishing standards regarding occupational safety and health,” and “clearly addressing the responsibility.” The law is based on the duties of the employer and government and the rights and duties of workers. The law generally describes the minimum standard, and the user should extend the concept of protection in law. This article describes the Occupational Safety and Health Act related to mental health protection. The data is expected to help medical doctors better understand and apply the law as a concept of protection.
PEGylation density-modulated anticancer drug release on gold nanoparticles in live cells
윤진하,Erdene Ochir Ganbold,주상우 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.33 No.-
Glutathione (GSH)-triggered drug releases of the anticancer drug mitoxantrone from a polyethyleneglycol (PEG) (molecular weight: 5000) density-modulated drug delivery system up to 0.57 nm 2 of goldnanoparticles (AuNPs) were examined using bimodal spectroscopic imaging techniques of live-cellfluorescence imaging and surface-enhanced resonance Raman scattering (SERRS). Prolonged deliveryamounts and sustained drug releases after introducing a high PEG density on AuNPs was supported by acell viability test in HeLa cells. A subcutaneous in vivo test also indicated that the SERRS spectra could beobserved only for the PEGylated AuNPs after external GSH treatment in consistent with the fluorescencemeasurements.