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      • KCI등재

        Clinical and hematologic manifestations in patients with Diamond Blackfan anemia in Korea

        김순기,안효섭,백희조,Bin Cho,Eun-Jin Choi,Nak-Gyun Chung,황평한,Dae-Chul Jeoung,강형진,Hyery Kim,고경남,구홍회,국훈,이광철,임호준,임영탁,유철주,박준은,Kyung-Duk Park,박상규,유경하,서종진,신희영,성기웅,유은선 대한혈액학회 2012 Blood Research Vol.47 No.2

        Background Diamond Blackfan anemia (DBA), characterized by impaired red cell production, is a rare condition that is usually symptomatic in early infancy. The purpose of this study was to assess nationwide experiences of DBA encountered over a period of 20 years. Methods The medical records of 56 patients diagnosed with DBA were retrospectively reviewed from November 1984 to July 2010. Fifteen institutions, including 13 university hospitals, participated in this study. Results The male-to-female ratio of patients with DBA was 1.67:1. The median age of diagnosis was 4 months, and 74.1% were diagnosed before 1 year of age. From 2000 to 2009, annual incidence was 6.6 cases per million. Excluding growth retardation, 38.2% showed congenital defects: thumb deformities, ptosis, coarctation of aorta, ventricular septal defect, strabismus, etc. The mean hemoglobin concentration was 5.1±1.9 g/dL, mean corpuscular volume was 93.4±11.6 fL, and mean number of reticulocytes was 19,700/mm3. The mean cellularity of bone marrow was 75%, with myeloid:erythroid ratio of 20.4:1. After remission, 48.9% of patients did not need further steroids. Five patients with DBA who received hematopoietic transplantation have survived. Cancer developed in 2 cases (3.6%). Conclusion The incidence of DBA is similar to data already published, but our study had a male predilection. Although all patients responded to initial treatment with steroids, about half needed further steroids after remission. It is necessary to collect further data, including information regarding management pathways, from nationwide DBA registries, along with data on molecular analyses.

      • KCI등재

        The prevalence of anemia and iron depletion in the population aged 10 years or older

        김순기,Hee Sook Kang,김철수,Young Taek Kim 대한혈액학회 2011 Blood Research Vol.46 No.3

        Background :Anemia and iron depletion continue to be common disorders in the world. This study was aimed at assessing the prevalence of anemia and iron depletion in apparently healthy Koreans aged 10 years or more. Methods :We used the data of the 4th Korean National Health & Nutrition Examination Survey (KNHANES), which assessed 7,607 individuals (3,337 males and 4,270 females). Iron depletion was defined as serum ferritin less than 15 ng/mL. Results :In males, mean hemoglobin (Hb) concentration decreased after the age of 50. The prevalence of anemia was 7.1% in 60 to 69 year olds and 12.3% in men aged 70 or older. As for females, the prevalence of anemia was 8.8% in 15 to 17 year olds, 16.7% in 18 to 49 year olds, 10.9% in 60 to 69 year olds, and 18.2% women aged 70 or older. In males, the prevalence of iron depletion was 8.6% at ages 10 to 14 years, 3.9% at 15 to 17, and 2.6% at 70 years or older. In females, the prevalence of iron depletion was 17.2% at ages 10 to 14 years, 24.1% at 15 to 17, 33.0% at 18 to 49, and 5.7% at 70 years or older. Although normocytic anemia was most common in both males and females, the proportion of microcytosis and macrocytosis increased at age 70 or older. Conclusion :The prevalence of anemia and iron depletion was high in women of reproductive age and in the elderly. Considering the rapid increase in the older population, an intervention to prevent anemia and iron depletion is imperative.

      • KCI등재

        순천 환선정(喚仙亭)의 역사적 변천에 따른 경관 변화와 시사점

        김순기,Kim, Soon-Ki 한국전통조경학회 2022 한국전통조경학회지 Vol.40 No.3

        This study examines the historical transition process of Hwanseonjeong Pavilion in Suncheon, identifies the landscape of the original Hwanseonjeong Pavilion in the past and its constituent elements, and compares it with the landscape of the present Hwanseonjeong Pavilion at Jukdobong area. It was intended to identify the problems and draw implications for future restoration of Hwanseonjeong Pavilion. Hwanseonjeong pavilion, the subject of this study, was built in 1543 by Tong-won Shim, the governor of Seungpyeong, as a garden architecture for government. Since then, it has been renovated several times, and as a pavilion representing "Seonhyang(immotal world)" Suncheon in the past, it was located along with an artificially created lake and other elements of the garden at a location where can be seen Dongcheon stream and Jukdobong Peak on the opposite side at a glance. Hwanseonjeong pavilion, which had been safely maintained during the Japanese colonial period, was lost on August 28, 1968 due to a major flood in Suncheon. The difference between Hwanseonjeong Pavilion and other lost is that another Hwanseonjeong Pavilion for the role of archery was built on Jukdobong Peak in 1935, before it was destroyed. The restoration case of Hwanseonjeong pavilion provides the following important implications for the restoration of pavilions as a garden architecture: First, the value of a pavilion is not formed from the building itself, but from the relationship with the surrounding landscape. Therefore, restoration of a pavilion should not be approached in the same way as restoration of buildings. Restoration of a pavilion requires efforts to understand the existing landscape value and to restore landscape elements together with buildings. Second, an artificially created long north-south lake along with Hwanseonjeong pavilion was a very important landscape component and a means of providing a way to enjoy the landscape. For restoration in the cultural context of Hwanseonjeong pavilion, efforts are also required to restore not only the architecture, but also the experience of cultural activities through an integrated examination and restoration based on an understanding of the cultural activities performed in Hwanseonjeong Pavilion. Third, compared to the past original Hwanseonjeong Pavilion, the existing Hwanseonjeong Pavilion shows a different shape, composition, scale, color, etc. In terms of the restoration of buildings, it is thought that restoration will be possible only when restoration is done through more accurate historical evidence, research, and investigation.

      • SCOPUSKCI등재

        농촌주부(農村主婦)들의 의료(醫療)와 항생제(抗生劑)에 대(對)한 지식(知識)과 태도(態度)에 관(關)한 조사(調査)

        김순기,Kim, Soon-Ki 대한예방의학회 1976 예방의학회지 Vol.9 No.1

        A study was conducted during the period of August 13 to August 18, 1974 to obtain information on knowledge and attitude of the rural area housewife toward health care and antibiotics using. Interviewed 242 housewives dwelling in Soodong and Hwado Myun, Yangju Gun, Kyunggi Do, a typical rural area in Korea and the following results are obtained: 1. Of 242 housewives interviewed, 20.2% were illiteracy, 68.2% was graduated from primary school, 9.1% from middle school and 2.5% from high school. 2. Of those interviewed, 8.7% were Christian, 5.0% Bueldist, 2.9% Confucianism, and 83.4% of those were no religious preference. 3. Utility rate according with the kind of mass media in home was 85.1% of respondants possessed radio, 16.1% of magazine, 12.8% of newspaper, and 4.1% of television. 4. In the case of patients occure in a family, 13.0% out of 242 respondants had chosen physician's clinics for inicial medical care place, 58.4% drug stores, 0.9% herb medicine and 27.7% of those had chosen folk medicine at home. 5. Antibiotics effective complaints listed by the respondants were skin diseases with 43.8%, suppurated wound 30.0%, URI like symptoms 18.2%, diarrhea 14.5%, low back pain 12.9%, fever 6.2%, loss of appetite 3.3%, all kind of diseases 2.5%, urethral discharge 2.1% and tuberculosis 0.8% respectively. 6. Only 14.7% of respondants had obtained antibiotics for medical care from physician's clinics and 85.3% of the respondants had obtained antibioties from drug store (70.7%), village shop (10.4%), and salesmen in street market without any physician's prescription. 7. Eighty-nine percent of the respondants were understanding on patient care activity as the local health subcenter but only 11.0% of those on M.C.H., 29.0% of those on family planning, 21% on vaccination, and only 6.6% on tuberculosis control activity. 8. Utility rate of the local health subcenter was 71.9% out of the patients indicated medical care of medical facilities.

      • SCOPUSKCI등재
      • 포스터 : 상호운용성 표준을 지원하는 이러닝 원격관리 솔루션(LENS)

        김석희 ( S H Kim ),김동정 ( D J Kim ),박지수 ( J S Park ),정대용 ( D Y Jung ),임종범 ( J B Lim ),김정환 ( J H Kim ),김순기 ( S K Kim ),홍석원 ( S W Hong ),유헌창 ( H C Yu ) 한국컴퓨터교육학회 2012 한국컴퓨터교육학회 학술발표대회논문집 Vol.16 No.2

        이러닝 표준화와 관련하여 해외 동향을 살펴 보면 선진국간의 치열한 경쟁이 심화되고 있는 상황이지만, 그에반해 국내 산업 및 국가 지식경쟁력 강화를 위한 실천적인 표준화 규격 및 우수 사례 개발은 부족한 것이 현실이다. 콘텐츠 표준화와 관련된 주요 규격은 SCORM 진영과 Common Cartridge가 있고 이들은 나름대로 영역을 구축하고 있어 이들 사이의 상호운용성이 요구되고 있다. 또한 급변하는 정보기기 환경에 따라 모바일, 3D 등의 이러닝 응용 프로그램들을 이종의 LMS에서 실행할 수 있는 여건 조성이 필요하다. 본 연구에서는 모바일 및 다양한 환경을 지원하는 LMS 인 LENS를 중심으로 상호운용성 지원 현황을 분석하고, 지식사회의 도래 및 다양한 학습환경을 대비한 LMS를 위한 요구사항을 연구 제안하였다. 결론적으로 현재까지 개발된 LMS 는 콘텐츠 중심의 상호운용성을 지원하고 있다. 그러므로 모바일이나 증강현실, 3D를 지원하는 응용 소프트웨어를 다양한 LMS에 실행하기 위한 표준 적용 방안을 연구하여 제안하였다.

      • KCI등재

        종목별 초경 전,후 여자선수의 빈혈 및 철분 상태에 관한 연구

        김광회 ( Kwang Hoi Kim ),김순기 ( Soon Ki Kim ),김도윤 ( Do Yun Kim ),김원현 ( Won Hyun Kim ),박동호 ( Dong Ho Park ) 한국스포츠정책과학원(구 한국스포츠개발원) 2004 체육과학연구 Vol.15 No.1

        본 연구의 목적은 필드하키, 농구, 핸드볼 종목의 사춘기 여자선수들을 대상으로 혈액의 생화학적 검사를 통하여 체내 철분함유 및 빈혈의 실태를 파악하고 초경 전ㆍ후의 철분영양상태를 살펴봄으로써 종목별 사춘기 여자선수들의 빈혈 및 철분상태에 대한 기초자료를 제공하는데 있다. 본 연구를 위하여 인천소재 고등학교 필드하키, 농구, 핸드볼선수 84명을 대상으로 초경전과 초경을 시작한 집단으로 구분하여 설문조사를 실시하였으며, 또한 혈액검사를 통하여 헤모글로빈(Hb), 헤마토크릿(Hct), 평균적혈구용적(MCV), 평균적혈구색소량(MCH), 백혈구(WBC), 적혈구(RBC), 총철분결합능력(TIBC), 페리틴(ferritin) 및 철분(iron)을 측정하였다. 이원배치 분산분석을 이용하여 얻은 결과는 다음과 같다. ① 종목간 모든 혈액성분 및 철분 영양상태에서 유의한 차이가 없는 것으로 나타났으나(p>.05), 종목들 중 핸드볼 선수들의 Hb, RBC, ferritin, iron에서 낮은 경향을 보였다. ② 종목별 초경 전ㆍ후의 선수들에 대한 빈혈실태를 파악한 결과에서는 초경 전ㆍ후에 따른 차이가 없었으며, 유사한 경향을 나타내었다. 결론적으로 초경 전ㆍ후와 관계없이 핸드볼 종목의 선수들이 가장 높은 빈혈 발생빈도를 나타냈으며 Hb, RBC, ferritin과 iron에서도 낮은 경향을 보였다. 철분섭취의 필요성이 강조되는 육상과 같은 유산소 운동종목뿐만 아니라 핸드볼을 비롯한 필드 하키, 농구 등과 같은 대부분의 구기 종목의 운동선수에게 있어서도 인체 내 철분이 부족할 경우, 지적 수행능력 및 경기에 대한 집중력이 저하될 수 있으므로 운동경기 중 최고의 기량을 발휘하기 위해서는 철분을 비롯한 영양섭취에 대한 관심과 개선이 필요할 것이다. 특히, 핸드볼과 같은 인체의 충격 또는 접촉이 심한 종목의 경우는 철분 및 관련 영양섭취에 대한 더욱 세심한 관리 와 지도가 필요할 것이다. The purpose of this study is to compare the status of iron among adolescent female athletes of different sports, Field hockey, Basket ball, Handball and to provide the materials of adolescent female athletes for iron improvement. The subjects were 84 adolescent female athletes whose age was from 14 to 16 years. Each subject was interviewed with questionnaires for daily training time and the status of menarche. We also measured hemoglobin (Hb), hematocrit (Hct), mean corposcular volume (MCV), mean corpuscular hemoglobin (MCH), white blood cell (WBC), red blood cell (RBC), total iron binding capacity (TIBC), ferritin. The results of this present study were as follows: There was no significant difference among the sport events (p<.05), but Handball had the trends which showed the lower Hb, RBC, ferritin, iron than other sport events and there was higher frequency of iron deficiency anemia (IDA), iron deficiency and ferritin deficiency. In addition, anemia frequency in Handball athletes was higher than other events. In conclusion, although the sport events were anaerobic characteristic, iron might have an effect on intelligent and concentrative capacity of all the games including aerobic and anaerobic sports. Therefore, there should be needed to increase the intake of iron for female adolescent athletes regardless of the menarche. Especially, the sport event such as Handball gets a shock or keeps in contact with other player. Hence, Handball players need to be carefully managed and educated about iron intake and nutrition related iron.

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