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      • KCI등재

        The Activity of Phosphoinositide-Specific Phospholipase C Is Required for Vegetative Growth and Cell Wall Regeneration in Coprinopsis cinerea

        오영택,안춘섭,이경진,김정근,노현수,김재원,이창원 한국미생물학회 2012 The journal of microbiology Vol.50 No.4

        Three isotypes of phosphoinositide-specific phospholipase C designated CcPLC1, CcPLC2, and CcPLC3 were identified in Coprinopsis cinerea, through a search of the genome sequence database. The functional role of the PI-PLCs were studied by using U73122, which specifically inhibits the activity of PI-PLC. The specificity of the inhibitor effect was confirmed by using an inactive structural analog U73433. The inhibition of PI-PLCs activity resulted in severely retarded germination of basidiospores and oidia, reduced hyphal growth, knobbly hyphal tips with many irregular side branches, and aberrant (branch-like structure) clamp cells. Furthermore, U73122 definitely inhibited cell wall formation. Here we report that PI-PLCs play important roles in various aspects of C. cinerea biology.

      • KCI등재

        한국판 운동의존성 척도의 타당화 검증

        오영택,양명환 국기원 2019 국기원태권도연구 Vol.10 No.3

        The purpose of this study was to verify whether the Exercise Dependence Scale-Korean Version(EDS-K) can be applied to Korean Taekwondo athletes properly and reliably. Two separate studies were conducted to achieve this goal. In study 1, 231 Taekwondo athletes were included, in study 2, 355 athletes were participated. Construct validity was verified through exploratory and confirmatory factor analysis, and criterion-related validity was verified through correlation analysis with the criterion variables, and were examine internal consistency reliability analysis. The main results were as follows. First, in study 1, seven factors were extracted from 21 items through exploratory factor analysis. The 21 item 7 factor scale obtained a good reliability value and confirmed the 7 factor structure through confirmatory factor analysis. Convergent validity and discriminant validity were also found to be good. Second, criterion-related validity was obtained through the correlation analysis between passion, deliberated practice and the seven factors of EDS-K developed in this study. Second, as a result of study 2, the factor structure shown in study 1 was reproduced and adequate validity(convergent and discriminant) and internal consistency were reverified. We also reaffirmed the criterion-related validity through correlation analyses between passion, perfectionism, deliberated practice, shame and EDS-K. Third, the construct validity was analyzed by the experimental method, and there were significant differences according to gender and school level. In conclusion, EDS-K is a multidimensional tool that can reliably and properly measure the exercise dependence of Korean Taekwondo athletes. 본 연구의 목적은 한국판 운동의존성 척도(EDS-K)가 우리나라 태권도선수들에게도 타당하고 신뢰롭게 적용될 수 있는지 여부를 검증하였다. 연구 1에서는 태권도 선수 231명을 대상으로, 연구 2에서는 태권도 선수 355명을 대상으로 이루어졌다. 탐색적, 확인적 요인분석을 통해 구인타당도를 검증하고 준거변인들과의 상관관계 분석을 통하여 준거타당도 검증과 신뢰도분석을 실시하여 다음과 같은 주요 결과를 추출하였다. 첫째, 탐색적 요인분석을 통하여 21문항 7개의 요인을 추출하였다. 21문항 7요인 척도는 양호한 신뢰도 값을 얻었으며, 확인적 요인분석을 통해 7요인 구조를 확증하였다. 또한 본 척도의 수렴타당성과 판별타당성도 양호한 것으로 나타났다. 열정, 의도적 연습 변인들과 본 연구에서 개발된 7요인들 간의 상관관계분석을 통하여 적절한 준거타당도를 확보하였다. 둘째, 연구 2의 분석결과 연구 1의 요인구조를 재확인하였고, 적절한 수준의 타당도와 신뢰도를 확보하였다. 또한 열정, 완벽주의, 의도적 연습, 수치심과 EDS-R간의 상관분석을 통하여 구인타당도를 재확인하였다. 셋째, 구인타당도 분석 결과, 성별과 학교급간에 따라서 유의한 차이를 보였다. 결론적으로 EDS-K는 한국 태권도선수들의 운동의존성을 신뢰롭고 타당하게 측정할 수 있는 다차원의 도구임을 확인하였다.

      • KCI등재

        사육탕가미방(四六湯加味方)이 streptozotocin으로 유발(誘發)된 백서(白鼠)의 실험적(實驗的) 탕뇨(糖尿)에 미치는 영향

        오영택,김동우,Oh, Young-Taek,Kim, Dong-Woo 대한한의학방제학회 2006 大韓韓醫學方劑學會誌 Vol.14 No.2

        Objectives : The objective of this study is to observe the effect of Saryuktangkamibang, Saryuktang with Liriopis Tuber, Lycii Fructus, Schizandrae Fructus, and Bombyx Batryticatus, on the experimental diabetes. Methods : In order to induce diabetes experimentally, injected streptozotocin to the vein in the tail of rats and then treated oral administration of Saryuktangkamibang water extracts. In the measurement of the variation levels of glucose, ALP, creatinine, and BUN concentration for each concentration levels for serum (0.2g/100g, 0.4g/l00g, 0.6g/100g), concentration level of glucose significantly decreased in 0.4g/l00g concentration level of Saryuktangkamibang. With this 0.4g/l00g concentration level of Saryuktangkamibang, the following conclusion was derived from the measurement of the serum levels of glucose. ALP, AST, ALT, creatinine, and BUN concentration for the injection of each 4th, 11th, and 18th day. Results : 1. In the measurement for each concentrations, the glucose concentration level in the serum significantly decreased on the 9th day in the Saryuktangkamibang-dosed group. 2. The creatinine and BUN concentration level in the serum significantly decreased on the 9th day in the Saryuktangkamibang-dosed group to which 0.6g/100g injected. 3. In the measurement for each dosage dates, the glucose concentration level in the serum significantly decreased on the 11th day in the Saryuktangkamibang-dosed group to which 0.6g/100g injected. 4. The AST concentration level in the serum significantly decreased on the 11th day in the Saryuktangkamibang-dosed group. Conclusion : Saryuktangkamibang, Saruktang with Liriopis Tuber, Lycii Fructus, Schizandrae Fructus, and Bombyx Batryticatus, has an effect of hypoglycemia, with no hepato-renal dysfunction. For the experimental results above, in that nephrotoxicity significantly decreased on the 0.6g/100g concentration, another research such as study for effect in other ranges and study for effect of dosage term except the concentration range of this study is necessary. Also dosage of appropriate concentration of Saryuktangkamibang is thought to provide valuable aid to cure on diabetes.

      • KCI등재

        Samter’s Triad 환자에서 Tramadol 주사 후 발생한 급성 천식 발작 1예

        오영택,조경래,최정환,허건 대한이비인후과학회 2010 대한이비인후과학회지 두경부외과학 Vol.53 No.2

        Samter’s triad is a well known syndrome and is characterized by a triad of asthma, aspirin or NSAID sensitivity and chronic sinusitis with nasal polyp. Chronic sinusitis with Samter’s triad is difficult to treat completely and has poor prognosis. Tramadol is a non-opioid analgesic that rarely shows respiratory suppression and is known to be relatively safe because it does not inhibit prostaglandin synthesis. For that reason, patients with asthma may avoid drug-induced exacerbations of the disease by substituting Tramadol for NSAIDs. We experienced a case of asthma attack in a patient with Samter’s triad after Tramadol injection. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:121-5

      • KCI등재

        한국 밀리치료사들의 근무 현황 조사

        오영택,배성수,전제균,라기용,문향미 대한물리치료학회 1998 대한물리치료학회지 Vol.10 No.1

        The purpose of this article is to identify real problems and to have a view of the future an Korean physical therapy of it through the survey. Moreover we make a statement for the justification acquiring the rights of practing physical therapiests with this fundamental data. The survey was conducted on 368 employed physical therapiests males 164, female 190 in Korea from April 1 to 30 in 1998 with self-administered questionnaire. The following results were obtained: 1. Of the 323 cases, 121(37.46%) work in local clinics, 55(17.02%) in hospitals, 103(31.89%) in general hospital and 21(9.60%) in rehabilitation centers or public welfare facilities. 2. In investigation of annual salary, the most common annual salary was more than 20million won in male(22.67%) and 12-14million won in female(35.36%). 3. The age group of 27-29 years accounted far 32.32% in male and 24-26 years accounted for 46.77% in female of the total physical therapiests are the highest. 4. In job satisfaction, 44.5% of physical therapiests who work in general hospital are generally satisfied and 25% are unsatisfied. 5. The periods of clinical practice for which physical therapicsts expect to devote are 1.64(44.81%) consider less than 10years, and 67(18.31%) expect 20years, 6. The problems of physical therapy system in korea are deviated administration of a cantral executive committee(39.94%) and excessive production of resistered physical therapiests.

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