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치매(痴?)의 침구치료(鍼灸治療)에 대(對)한 문헌적(文獻的) 고찰(考察)
김동석,서상수,권순철,Kim, Dong-Suk,Seo, Sang-Su,Kwon, Sun-Chul 경락경혈학회 2004 대한침구의학회지 Vol.21 No.2
Objectives : This study is designed to investigate the pathology, acupuncture and moxibustion therapy applicable of the dementia through literature of oriental medicine. Results : The findings of this study are as follows ; 1. The cause of dementia is internal damage of seven emotions(七情內傷), deficiency of the kidney essence(腎精不足), retention of dampness in the mental(痰迷心竅). 2. The acupuncture meridians used often for dementia are $Tok-maek(GV),\;Chok-t'aeyang\;Pang-gwang-Ky\check{o}ng(BL),\;Chok-yangm\check{o}yng\;Wi-Ky\check{o}ng(ST),\;Su-gwor\check{u}m\;Shimp'o-Ky\check{o}ng(PC),\;Su-so\check{u}m\;Shim-Ky\check{o}ng(HT)$. 3. The spots on the body suiTable for acupuncture used for therapy of the dementia are 98 points and extra points are 6 points, total therapeutic acupunture points are 104 points. And acupunture points are frequently used Shinmun(神門-HT7, 24), Paek'oe(百會-GV20, 19), Chok-samni(足三里-ST36, 18), Sugu(水溝-GV26, 17), P'ungnyung(豊隆-ST40, 16), Taech'u(大椎-GV14, 14), $Sam\check{u}mgyo(三陰交-SP6,\;14)$, Shimsu(心兪-BL15, 14), $Taen\check{u}ng(大陵-PC7,\;11)$, Nogung(勞宮-PC8, 11), Sosang(少商-LU11, 10), Kansa(間使-PC5, 10), Naegwan(內關-PC6, 10). 4. The acupoints used often on moxibustion are Paek'oe(百會-GV20), Chang-gang(長强-GV1), Taech'u(大椎-GV14), Kansa(間使-PC5). Conclusion : It is recommended that further study of many sided investigations in the future.
치매(痴매)의 침구치료(鍼灸治療)에 대(對)한 문헌적(文獻的) 고찰(考察)
김동석 ( Dong Suk Kim ),권순철 ( Sun Chul Kwon ),서상수 ( Sang Su Seo ) 대한경락경혈학회 2004 Korean Journal of Acupuncture Vol.21 No.2
Objectives: This study is designed to investigate the pathology, acupuncture and moxibustion therapy applicable of the dementia through literature of oriental medicine. Results: The findings of this study are as follows; 1. The cause of dementia is internal damage of seven emotions(七情內傷), deficiency of the kidney essence(腎精不足), retention of dampness in the mental(痰迷心竅). 2. The acupuncture meridians used often for dementia are Tok-maek(GV), Chok-t`aeyang Pang-gwang-Kyong(BL), Chok-yangmyong Wi-Kyong(ST), Su-gworum Shimp`o-Kyong(PC), Su-soum Shim-Kyong(HT). 3. The spots on the body suiTable for acupuncture used for therapy of the dementia are 98 points and extra points are 6 points, total therapeutic acupunture points are 104 points. And acupunture points are frequently used Shinmun(神門-HT7, 24), Paek`oe(百會-GV20, 19), Chok-samni(足三里-ST36, 18), Sugu(水溝-GV26, 17), P`ungnyung(豊隆-ST40, 16), Taech`u(大椎-GV14, 14), Samumgyo(三陰交-SP6, 14), Shimsu(心兪-BL15, 14), Taenung(大陵-PC7, 11), Nogung(勞宮-PC8, 11), Sosang(少商-LU11, 10), Kansa(間使-PC5, 10), Naegwan(內關-PC6, 10). 4. The acupoints used often on moxibustion are Paek`oe(百會-GV20), Chang-gang(長强-GV1), Taech`u(大椎-GV14), Kansa(間使-PC5). Conclusion: It is recommended that further study of many sided investigations in the future.
( Su Sun Kim ),( Kyung Up Kim ),( Sung Jun Kim ),( Seung In Seo ),( Hyoung Su Kim ),( Myoung Kuk Jang ),( Hak Yang Kim ),( Woon Geon Shin ) 대한내과학회 2019 The Korean Journal of Internal Medicine Vol.34 No.2
Background/Aims: Selecting patients with an urgent need for endoscopic hemostasis is difficult based only on simple parameters of presumed acute upper gastrointestinal bleeding. This study assessed easily applicable factors to predict cases in need of urgent endoscopic hemostasis due to acute upper gastrointestinal bleeding. Methods: The consecutively included patients were divided into the endoscopic hemostasis and nonendoscopic hemostasis groups. We reviewed the enrolled patients’ medical records and analyzed various variables and parameters for acute upper gastrointestinal bleeding outcomes such as demographic factors, comorbidities, symptoms, signs, laboratory findings, rebleeding rate, and mortality to evaluate simple predictive factors for endoscopic treatment. Results: A total of 613 patients were analyzed, including 329 patients in the endoscopic hemostasis and 284 patients in the non-endoscopic hemostasis groups. In the multivariate analysis, a bloody nasogastric lavage (adjusted odds ratio [AOR], 6.786; 95% confidence interval [CI], 3.990 to 11.543; p < 0.0001) and a hemoglobin level less than 8.6 g/dL (AOR, 1.768; 95% CI, 1.028 to 3.039; p = 0.039) were independent predictors for endoscopic hemostasis. Significant differences in the morbidity rates of endoscopic hemostasis were detected between the group with no predictive factors and the group with one or more predictive factors (OR, 2.677; 95% CI, 1.920 to 3.733; p < 0.0001). Conclusions: A bloody nasogastric lavage and hemoglobin < 8.6 g/dL were independent predictors of endoscopic hemostasis in patients with acute upper gastrointestinal bleeding.
A Case of Congenital Fiber Type Disproportion with Multiple Anomalies
Su Young Seo(서수영),Young Mock Lee(이영목),Se Hoon Kim(김세훈),Tai Seung Kim(김태승),Joon Soo Lee(이준수),Heung Dong Kim(김흥동) 대한소아신경학회 2006 대한소아신경학회지 Vol.14 No.2
Congenital fiber type disproportion (CFTD)은 근긴장도 저하, 발달 지연, 관절 구축, 골격계 이상 등의 임상 증상을 나타내는 선천성 근육질환으로 근육 조직 소견에서 1형 근섬유의 크기 감소와 수적 증가를 특징으로 하는데 1형 근섬유가 2형 근섬유보다 지름이 12% 이상 작아야 한다. 저자들은 근긴장도 저하, 발달 지연, 정신 지체, 전신성 강직 간대 발작, 잠복고환, 고관절 불완전탈구, 발목관절 구축, 미만성 뇌위축, 시신경 위축 등의 소견을 보이면서 근육조직 검사에서 확진된 CFTD 1례를 경험하였기에 이를 보고하고자 한다. Congenital fiber type disproportion (CFTD) is a rare form of congenital myopathy characterized by the smallness and the marked predominance of type 1 fibers, which presents congenital hypotonia, delayed motor milestones, joint contractures, and skeletal deformities. The muscle biopsy reveals the type 1 fibers are more than 12% smaller than the type 2 fibers in size. We describe a 24-month-old boy who presented muscle hypotonia, delayed motor milestones, mental retardation with generalized tonic clonic seizures, and the muscle pathologic findings of CFTD. Additional findings included left cryptorchidism, congenital subluxation of the hip, contractures of ankle joints, diffuse brain atrophy, and optic nerve atrophy. We should consider CFTD as a differential diagnosis of early onset myopathy.
Immune regulation through tryptophan metabolism
Seo Su-Kil,Kwon Byungsuk 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Amino acids are fundamental units of molecular components that are essential for sustaining life; however, their metabolism is closely interconnected to the control systems of cell function. Tryptophan (Trp) is an essential amino acid catabolized by complex metabolic pathways. Several of the resulting Trp metabolites are bioactive and play central roles in physiology and pathophysiology. Additionally, various physiological functions of Trp metabolites are mutually regulated by the gut microbiota and intestine to coordinately maintain intestinal homeostasis and symbiosis under steady state conditions and during the immune response to pathogens and xenotoxins. Cancer and inflammatory diseases are associated with dysbiosis- and host-related aberrant Trp metabolism and inactivation of the aryl hydrocarbon receptor (AHR), which is a receptor of several Trp metabolites. In this review, we focus on the mechanisms through which Trp metabolism converges to AHR activation for the modulation of immune function and restoration of tissue homeostasis and how these processes can be targeted using therapeutic approaches for cancer and inflammatory and autoimmune diseases.
Su-Jeong Seo,Jae Youl Cho,Yeon Ho Jeong,Yong-Soon Choi 고려인삼학회 2013 Journal of Ginseng Research Vol.37 No.2
Korean red ginseng (KRG) is prepared by the process of steaming the roots of Panax ginseng. In this study, the feeding effects of KRG-water extract (KRGE) on ethanol-induced liver damage were elucidated by measuring serum biomarkers in rats. Serum g-glutamyltranspeptidase (g-GT) activity and the concentration of malondialdehyde (MDA) were significantly increased by shortterm and long-term ethanol treatment in rats, whereas the activities of serum glutamate pyruvate transaminase (GPT) and glutamate oxaloacetate transaminase (GOT) did not respond. Pretreatment with KRGE maintained the activity of serum GPT, and the MDA concentration induced by short-term ethanol ingestion remained within the normal range. However, co-feeding of KRGE to rats decreased the concentration of MDA but failed to modulate the serum g-GT activity induced by long-term ethanol treatment. Our studies suggest that in rats, it appears that KRGE does not sufficiently reverse the physiological response evoked by long-term ethanol ingestion to maintain normal conditions, in view of the serum biomarker g-GT, regardless of KRGE’s favorable antioxidant activity.