淸熱利水湯의 效能에 對한 實驗的 硏究

姜信仁,金性洙,申鉉大 경희대학교 1989 慶熙醫學 Vol.5 No.3

두부손상 환자의 정신과적 합병증에 관한 장애 감정례의 일반 사항에 관한 분석

신석철,왕성근,신윤오,김덕호,김상국,강동숙 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

Authorst ried retrospective analysis to find out general characteristics of the patients undergoing disability evaluation at the department of psychiatry Chungnam National University Hospital from 1986 to 1990. The subjects, who were suffered from psychiatric complications due to head trauma by traffic accident, were 66 patients and they were classified depending on the demographic status, situations of traffic accident, evalaution periods, whether or not perform operation, and rates of evaluated disability and diagnosis. The results were summarized as follows. 1. General background of the subjects were as follows. 1) The frequency order of request were court(59 %) and insurance company(19.7%). 2) The place of accident was more common in large city, common accident vehicle were bus, truck, and cabs. 3) The season of accident were more common in Spring and Autumn. 2. Male(71.2%) was more common than in female and more common in the age group of 5-19 years old(37.9%). The most frequent job of the patients was labour, and the education level was more common in the graduates of elementary school(47.9% ). 3. The interval between accident and evaluation was most frequent in 12-23 months(47.5%), and duration of evaluation was mostly 14 to 21 days. Performed brain operation was 31.8% and non-operated patients was 50.0%. The rates of disability according to the McBride's disability evaluation were mostly belonged to the group of beow 40%(74.1%). 4. The final diagnosis after evaluation were organic personality disorder(45.5%) and dementia(31.8%).

Garcin 증후군으로 발현된 연골육종 1예

강성수,김명권,박현미,류근신,신동진 대한신경과학회 1999 대한신경과학회지 Vol.17 No.2

혈액 종양환자에서 Tobramycin의 임상약동학

신재국,신완균,장인진,신상구,김성민,배현주,최강원,김진규 대한화학요법학회 1990 대한화학요법학회지 Vol.8 No.1

항암화학요법을 받고 있던 중 감염으로 tobramycin을 투여받은 36명의 혈액종양 환자에서 tobramycin의 약동학적 특성을 비종양환자군에서의 population 값과 비교 검토하였다. 이들은 모두 정상 신기능을 가진 16세 이상의 성인남녀(21:15)백혈병 환자들이었다. 36명의 혈액종양 환자에서 산출된 tobramycin의 청소율 및 체내분포용적은 각각 120.3± 27.2ml/lg/hr 및 0.386± 0.11 L/㎏로 population 추정 치보다 유의하게 큰 값을 보였다.(P. <0.05).청소율과 체내분포용적을 해당 population 추정치로 나눈 비율치(ratio)의 평균값은 각각 1.47± 0.34 및 1.20± 0.34였다. 연령, hematocrit치, 혈청albumin치, 발열 및 항암화학요법기간과 tobramycin의 청소율 및 체내분포용적 사이에 유의한 상관관계는 발견할 수 없었다. 본 연구결과 혈액종양 환자에서 tobramycin 투여시는 적정혈장농도를 유지하기 위해 일반 환자군에 비해 용량의 증가 및 투여간격의 조정이 필요하며 지속적인 혈장농도 monitoring을 통하여 용법의 재적정화가 필요할 것으로 사료된다. The pharmacokinetics of tobramycin were evaluated in 36 hematologic malignancy patients undergoing anticancer chemotherapy and compared to the expected values from the population parameters. Total body clearance(mean : 12.3±27.2㎖/㎏/hr) and volume of distribution (mean : 0.386±0.11 L/㎏) in hematologic malignancy patients with normal renal function were significantly greater than those of estimated from population parameter distribution(P<0.05). The ratios of total body clearance and volume of distribution to the population estimates were 1.44±0.37 and 1.20±.034, respectively. No relationships were found between age, hematocrit, serum albumin, fever or duration of anticancer chemotherapy and pharmacokinetic parameters. It is suggested that the increment of tobramycin dose regimen wold be considered in patients with hematologic malignancy, and dose readjustment followed by close monitoring of plasma drug concentration would be required.

KAL기 추락에 의한 대량재해의 개인식별

강신몽,이원태,고영창,최상규,김윤희,이홍석,서재관,윤중진,이혜경,최득린,김종열,윤창육,변명식,이장홍 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2

Individual identification is an important part in medicolegal field especially in mass disaster. At July, 27, 1989, KAL KE-803 was crashed on landing at Tripoli International Airport, Liba. The plane was caught in fire and sixty eight Koreans were sacrified. The majority of victims were severely charred and injured. The authors examed all dead bodies and successfully identified all the cases through visual, anthropological, odontological, radiological and pathological methods including fingerprint and blood typing.

화재 피해를 입은 고 강도 철근 콘크리트 보의 보수 성능

신미경,신영수,이차돈,홍성걸,강지연 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

This paper is to evaluate practically the techniques and materials of repair for high strength concrete elements with fire damages as well as to investigate the structural behavior of beams according to pre- or post-repair after fire-damages. For this purpose, flexural specimens with high strength concrete were exposed to high temperatures by the ISO 834 specification. After natural cooling and post-fire-curing in a natural environment for 1 months, 6 specimens were loaded to failure after they were repaired with polymer cement mortar for 1 month curing.

정신분열병과 기분장애의 Cavum Septi Pellucidi에 관한 자기공명영상 연구

신상은,강민희,김철응,이정섭,배재남 대한신경정신의학회 2000 신경정신의학 Vol.39 No.4

연구목적: 뇌자기공명촬영술을 이용하여 정신분열병 환자와 기분장애 환자, 대조군의 Cavum Septi Pellucidi를 측정하여 정신분열병과 기분장애에서 생물학적인 원인 중 하나인 신경 발달학적 가설을 알아보는데 있다. 방법: 34명의 정신분열병 환자와 18명의 기분장애 환자, 22명의 대조군에게 자기공명촬영술을 시행하여 CSP의 출현 빈도 및 CSP의 크기에 따른 출현빈도를 비교분석하여 다음과 같은 결과를 얻었다. 결과: CSP의 출현 빈도는 정신분열병 환자에서 61%, 기분 장애환자에서 61%, 대조군에서 41%로 나타났다. T1 강조 축상 영상에서 가장 크게 보이는 단면에서 가로로 가장 긴 부분의 길이가 3mm 이상으로 정의한 큰 CSP의 출현빈도는 정신분혈병환자에서 24%, 기분 장애 환자에서 11%, 대조군에서 5%였고 정신분열병, 기분장애, 대조군의 순으로 높은 빈도를 보였으나 통계적인 유의성은 없었다. 결론: 정신분열병, 기분장애, 대조군의 순으로 큰 CSP의 빈도가 높은 경향성은 확인할수 있었으나 통계적으로 유의한 차이는 아니었다. 그러나 본 연구는 여러 가지 제한점이 있었기 때문에 신경발달학적 가설을 알아보기 위해서는 향후 환자수를 확대하고 보다 정교하게 고안된 연구가 필요하다. Objectives: This study was designed to verify neuro-developmental hypothesis of schizo-phrenia and mood disorder. Methods: We performed Brain Magnetic Resonance Imaging study in 34 schizophrenic patients, 18 mood disorder patients and 22 controls and compared the incidence and the size of carum septi pellucidi(CSP). Results: The incidences of CSP in schizophrenia, mood disorder and controls were 61%,61%, and 41%, respectively. The incidences of large CSP, defined as largest diameter larger than 3mm in T1-weighted image, were 24% in schizophrenic patients, 11% in mood disorder patients, and 5% in controls. But they didn't show statistically significant differences. Conclusion:We could find the tendency that the incidence of CSP was high as following order ; schizophrenia, mood disorder, controls. But it was not statistically significant difference. To verify neuro-developmental hypothesis, we need larger pool of patients and better study design.

Chitinase를 생산하는 Pseudomonas sp. YS-542의 분리 및 특성

강신욱,이준우,방광웅,최희상 慶北專門大學(영주경상전문대학) 2002 慶北專門大學 論文集 Vol.21 No.-

A chitinase-producing bacterium was isolated from soil by selective enrichmentment culture medium. The bacterium was identified as Pseudomonas sp. based on the data obtained from its morphological, cultural and biochemical characteristics. The isolated strain was named Pseudomonas sp. YS-542. The medium for the production of chitinase was consisted of colloidal chitin 1.0%, tryptone 1.0%, MgS04·7H2O 0.2%, K2HP04 0.1%. The optimum cultural temperature, initial pH and time for the best production of chitinase were 25℃, 48hrs and pH 8.0, respectively.

三天地의 環境과 生物多樣性 : I. Enviornmental Factors and Flora I. 環境要因과 植物相에 關하여

신상천,이종운,배규호,전재인,강경화 嶺南大學校 基礎科學硏究所 1992 基礎科學硏究 Vol.12 No.-

Environmental factors and phytological aspects of Samchunimpoundment in Kyongsan, Kyongpook were studied. 40 quadrats in 4 sites had 94% herbaceous cover, 31% shrub cover and 18% tree cover. Ambrosia artemisiifolia var. elatior, Metaplexis japonica, Erigeron annuus, Humulus Japonicus, Eragrostis ferruginea, Artemisia princeps var. orientalis were dominant herbaceous species and found cultivated plants of Hordeumn vulgare var. hexastichon, Prunus persica, Morus alba and neophytes of Ambrosia artemisiifolia var. elatior, Erigeron canadensis, Erigeron annuus, Ailanthus altissima, Bidens bipinnata, Lactuca indica var. laciniata, Robinia pseudo-acacia, oenothera odorata, Euphobia maculata. The investigated sites were divided into 4 patterns based on the vegetation with high difference level and Ambrosia artemisiifolia var. elatior, Medicago sativa, Setaria viridis, Metaplexis japonica, Humulus japonicus, Calystegia japonica, Forsythia koreana, Lsctuca indica var. laciniata were different species group. More than 90% on the surface area of water mass covered with Nelumbo nucifera, Marsilea quadrifolia and Typha angustata and distributed Hydrilla verticillata, Ceratophyllum demersum, Trypa pseudo-incisa, Myriophyllum spicatum under water. Average data of environmental factor analysis are as followings; air temperature 25.8℃, ph 6.77, total hardness 117.94㎎/ℓ, SS 4.5㎎/ℓ,Do 3.3㎎/ℓ,BOD 6.6㎎/ℓ,COD 7.2㎎/ℓ,cl- 17.56㎎/ℓ,?? 7.14㎎/ℓ,Mn 0.05㎎/ℓ, Zn 0.04㎎/ℓ. Total quality of impoundment water were heavily polluted and were quality class Ⅳ.

치위생과 학생들의 B형 간염 바이러스의 표지자와 인지도에 관한 연구

강은주,신상희,장선희 韓國學校保健學會 2002 韓國學校保健學會誌 Vol.15 No.2

This study is aimed at offering basic data about prevention of Hepatitis B virus and infection control to dental hygiene students who will work mostly at dental offices which are characteristically exposed to a high risk of HBV infection. For this study, surveyed were 188 sophomores and juniors of the dental hygiene department who volunteered to undergo the tests of HBsAg and HBsAb. The examination of the blood collected from the samples and analysis of their perception about hygiene resulted in following conclusion: Positive HBsAg Four was found in 4 testees(2.1%) while 118(62.8%) revealed positive. HBsAb. Juniors showed higher positive rate in HBsAb whereas sophomores had higher positive rate in HBsAb. But such difference has statistically no significance. Generally, students seemed to pay little attention to HBV, judging from the survey of their perception about the present state of HBsAb and HBsAb(p>0.05), conduct of infection(p<0.05), completion of 3 requested vaccination(p>0.05), and formation of antibody(p>0.05). With regard to the infection routes of HBV, most students(92.4%) replied "through blood", which is statistically insignificant, though. Next ratio goes to the reply "through contaminated injectors". This reply came more from sophomores than from juniors, a difference which is statistically significant(p<0.05). The lowest rate of possible infection(29.2%) was thought to be "through breast-feeding of a positive mother"(p<0.05). In general, it turned out that sophomores had more knowledge about the infection routes of HBV than juniors. In terms of clinical history among family members, 6(3.1%) reported that some of their family members are currently suffering from a liver complaint, 3(1.6%) replied their family members were once afflicted, and 4(2.1%) said their members died of hepatitis. Except 10(4.7%), all the surveyees replied that their states of health are better than normal. Generally, sophomores are healthier than juniors except for very health case, a difference which is statistically of no value.