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權五鍾,李周翰 경북대학교 공과대학 1983 工大硏究誌 Vol.12 No.-
A simple geometrical model for the interaction between second phase inclusions and grain boundary is suggested. This model indicates that the attracting force of second phase inclusions increases with the decrease in the dihedral angle of inclusions formed at grain boundary. The "joining angle" of grain boundary at which the attracting force shows the maximum value increases with the decrease in dihedral angle, too. Consequently, the maximum average grain size during grain growth is expected to be smaller with smaller dihedral angle.
完全高密度化된 液相燒結試片의 液相吸入現象에 미치는 固相粒子크기의 영향
權五鍾,李周翰,姜大甲 慶北大學校 1984 論文集 Vol.38 No.-
The effect of Co grain size on the liquid absorption of completely densified Co-Cu compacts by liquid phase sintering is investigated. The compacts of which composition is 80 wt. % Co-20 wt. % Cu, were prepared by ordinary powder metallurgy techniques. To eliminate pores completely and to vary the average size of solid Co grains, the compacts were sintered at 1250℃ for from 1.5-up to 32 hours. A small pellet of 11 wt. % Co-89 wt. % Cu was put into a small hole drilled at the specimen surface. Then the assembly was annealed at the same temperature for from one up to 17 hours. The pellet melted immediately and formed a liquid pool. The presintered body absorbed liquid from the pool. The smaller the solid grain size, the more liquid was absorbed. The amount of the absorbed liquid also increased with the increase of annealing time. The driving force of liquid absorption is expected to be the tendency of anhedral solid grains to restore spherical shape, of which interfacial free energy is lower.
( Dan Bi Lee ),( Young Hwa Chung ),( Sae Hwan Lee ),( Yoon Seon Lee ),( Don Lee ),( Jeong Eun Hwang ),( Kang Mo Kim ),( Young Suk Lim ),( Han Chu Lee ),( Eun Sil Yu ),( Young Sang Lee ),( Dong Jin Suh 대한소화기학회 2007 Gut and Liver Vol.1 No.1
Background/Aims: The authors examined whether the response to interferon (IFN) therapy can affect the development of hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients. Methods: Out of 353 biopsy-proven CHB patients, 229 (65%) were treated with IFN-α for 6 to 12 months. They were followed for a median period of 75 months (range, 6-120). In patients treated with IFN, biochemical and virologic responses were evaluated at the end of treatment (EOT). The cumulative incidence rates of HCC were calculated and analyzed in relation to baseline characteristics as well as biochemical and virologic responses to IFN therapy. Results: The overall cumulative incidence of HCC was 0%, 0.8%, 3.7% and 5.5% at 3, 5, 7 and 8 years, respectively. Age, serum AFP levels and the stage of fibrosis were significantly associated with the occurrence of HCC. As a whole, IFN therapy did not affect the occurrence of HCC. Among the patients treated with IFN, biochemical responders had low HCC incidence rates compared with non-responders (p=0.018). However, the HCC incidence rates of virologic responders were not different from non-responders (p=0.203). Conclusions: Biochemical rather than virologic response to IFN therapy may be more closely associated with decrease of HCC incidence in CHB patients. (Gut and Liver 2007;1:49-55)
Lee Myungsu,Chung Jin Wook,Lee Kwang-Hun,Won Jong Yun,Chun Ho Jong,Lee Han Chu,Kim Jin Hyoung,Lee In Joon,허세범,Kim Hyo-Cheol,Kim Yoon Jun,Kim Gyoung Min,Joo Seung-Moon,Oh Jung Suk 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.10
Objective: To assess the two-year treatment outcomes of chemoembolization with drug-eluting embolics (DEE) for nodular hepatocellular carcinoma (HCC). Materials and Methods: This study was a prospective, multicenter, registry-based, single-arm trial conducted at five university hospitals in Korea. Patients were recruited between May 2011 and April 2013, with a target population of 200. A DC Bead loaded with doxorubicin was used as the DEE agent. Patients were followed up for two years. Per-patient and perlesion tumor response analysis, per-patient overall survival (OS) and progression-free survival (PFS) analysis, and per-lesion tumor control analysis were performed. Results: The final study population included 152 patients, with 207 target lesions for the per-lesion analysis. At one-month, six-month, one-year, and two-year per-patient assessments, complete response (CR) rates were 40.1%, 43.0%, 33.3%, and 19.6%, respectively. The objective response (OR) rates were 91.4%, 55.4%, 35.1%, and 19.6%, respectively. The cumulative two-year OS rate was 79.7%. The cumulative two-year PFS rate was 22.4% and the median survival was 9.3 months. In multivariable analysis, the Child-Pugh score (p = 0.019) was an independent predictor of OS, and tumor multiplicity (p < 0.001), tumor size (p = 0.020), and Child-Pugh score (p = 0.006) were independent predictors of PFS. In per-lesion analysis, one-month, six-month, one-year and two-year CR rates were 57.5%, 58.5%, 45.2%, and 33.3%, respectively, and the OR rates were 84.1%, 65.2%, 46.6%, and 33.3%, respectively. The cumulative two-year per-lesion tumor control rate was 36.2%, and the median time was 14.1 months. The Child-Pugh score (p < 0.001) was the only independent predictor of tumor control. Serious adverse events were reported in 11 patients (7.2%). Conclusion: DEE chemoembolization for nodular HCCs in the Korean population showed acceptable survival, tumor response, and safety profiles after a two-year follow-up. Good liver function (Child-Pugh score A5) was a key predictor of per-patient OS, PFS, and per-lesion tumor control.
A new method for monitoring an OLED panel for lighting by sensing the wave-guided light
Han, Jun-Han,Moon, Jaehyun,Shin, Jin-Wook,Joo, Chul Woong,Cho, Doo-Hee,Hwang, Joohyun,Huh, Jin Woo,Chu, Hye Yong,Lee, Jeong-Ik The Korean Infomation Display Society 2012 Journal of information display Vol.13 No.3
In this work, we report on a new monitoring method for an organic light-emitting diode (OLED) panel for lighting by optical sensing of the wave-guided light in the substrate. Using microlens array films, the wave-guided light was extracted into the edge or back side of the panel to be monitored by a photodiode. The luminance of the extracted light was measured as linearly proportional to the front light. Thus, by converting the extracted light into photo voltage, monitoring the luminance change occurring in the OLED is possible. Based on the results and concepts, we have proposed a photodiode-equipped driving circuit which can generate compensated driving current for uniform luminance of OLED panels.