관동맥풍선시술중 혈전동반 병변에 대한 구조치료(Rescue Utilization)로서의 Abciximab(ReoPro^(�)의 효과

두영철,채경수,최종형,허필석,송관욱,홍경순,박대균,한규록,오동진,유규형,임종윤,고영박,이광학,이영 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.12

교육에서의 컴퓨터 활용에 따른 교사의 역할 전환

최욱,고영남 고려대학교 교육문제연구소 1998 敎育問題硏究 Vol.10 No.-

傳染性單核球增加症 1例 報告

金相仁,高光昱,趙漢翊,崔玲姬,崔勇,李在英 대한의학협회 1972 대한의학협회지 Vol.15 No.6

전방 십자 인대 파열에서의 반월상 연골판 파열의 양상

강충남,김종오,김동욱,고영도,유재두,최창호 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

Injury to associated structures is expected to worsen the prognosis of ACL tears. Meniscal injuries are well known to coexist in knees with both acute and chronic ACL injuries. However, it is not conclusive whether the likelihood of encountering a repairable meniscal lesion diminishes as the time from injury increases. W e reviewed records of 127 patient receiving an arthroscopically assisted stabilizing procedure for an acute and chronic ACL injury incurred while skiing, soccer, traffic accident to associated meniscal injury. All patient had undergone arthroscopic evaluation. We classified acute injury as injury less than 3 months old at time of surgery, and chronic injury as more than 3 months old. Acute injuries were 88 cases and chronic injuries were 39 cases. In 55 ski-related injuries, 41 knees were acute and 14 knees were chronic. Fourteen(34%) meniscal tears were noted in chronic cases. In 42 soccer injuries, 20 knees were acute and 22 knees were chronic. In acute cases, 14(70%) meniscal tears were noted and in chronic cases, 14(64%) meniscal tears were noted. In 30 traffic accident injuries, 27 knees were acute and 3 knees were chronic. In acute cases, 19(70%) meniscal tears were noted and in chronic cases, 2(67%) meniscal tears were noted. There was strong trend of the increased incidence of medial involvement in the non-skiers than in the skiers, In the type of meniscal tear with acute ACL rupture, 33 of 52 meniscal were longitudinal tear, 6 were horizontal tear, 4 were radial tear(only in lateral meniscus) and 9 were complex tear. In the pattern of meniscal tear with chronic ACL rupture, 15 of 37 meniscal were longitudinal tear, 3 were horizontal tear, 1 was radial tear(only in lateral meniscus) and 18 were complex tear(medial meniscus 16, lateral meniscus 2). In the treatment of torn menisci, 29 of 52 meniscal tears were treated by conservative treatment and meniscal repair, 21 meniscal tears were treated by partial menisectomy and 2 meniscal tears were treated by subtotal menisectomy in acute injuries. In chronic injury, 10 of 37 meniscal tears were treated by conservative treatment and meniscal repair, 18 meniscal tears were treated by partial menisectomy and 9 meniscal tears were treated by subtotal menisectomy. There was no total menisectomy. As the time from injury increased, the medial meniscus tears were severe and were more likely to require menisectomy.

병원근무자에 대한 특수건강진단 적용 가능성에 관한 연구

이수일,조병만,조봉수,김영욱,고광욱,문남출,김주원 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.2

병원근무자들에 대한 특수건강진단 적용 여부를 판단하기 위한 기초자료를 제공하기 위해 1995년 3월 10일부터 4주간에 걸쳐 부산시내에 위치하는 2개 종합병원 근무자 830명을 대상으로 설문조사를 시행해 얻은 결과를 요약하면 다음과 같다. 1. 조사된 43개 항목 중 10% 이상의 대상자가 유해요인에 폭로되고 있다고 응답한 항목은 소음, 분진 등 16개 항목이었다. 이 중 분진, 소음 및 스트레스는 연구대상자의 50%이상에서 폭로되고 있다고 응답했으며 그 외 알콜류 소독제(41.3%), 방사선(34.6%), 일반약제(33.3%)의 순으로 폭로되고 있었고 VDT의 경우 25.2%, aldehyde류는 18.7%에서 폭로되고 있는 것으로 나타났다. 2. 대상자의 63.1%에서 병원근무 환경 중에 유해인자가 존재한다고 응답했고 병원의 환경측정이 필요하다고 대답한 사람은 80%에 달했다. 35.7%가 유해인자에 대한 교육을 받은 적이 없다고 응답했다. 전체 응답자의 35.7%가 유해인자에 폭로시 보호 장비를 착용하지 않는다고 응답했고 주기적인(격년) 건강진단은 48.6%에서 받는 것으로 조사되었다. 근무부서의 환기상태는 7.2%만이 좋은 편이라고 응답했다. 이상에서 살펴본 바와 같이 병원근무자들이 여러 가지 유해환경에 노출되고 있고 또, 이로 인해 발생할 수 있는 건강장해에 대한 예방대책이 소홀한 것으로 나타나 병원의 작업환경측정의 시행이 필요하고 이 결과를 바탕으로 병원근무자들에 대한 특수건강진단 적용여부를 결정해야 할 것이다. This study was performed to decide the possibility of special health examination to the hospital employees. We carried out questionnaire survey for 830 subjects at 2 general hospitals located in Pusan city. The summary of this study are as follows. 1. Above 10% of total hospital employees were replied that they exposed to 16 hazard items, such as dust, noise, stress and etc. Among them, over 50% of hospital employees exposed to dust(69.8%), noise(52.3%), stress(60.1%). And hospital employees exposed to alcoholic disinfectant(41.3%), radiation(34.6%), drug(33.3%), VDT(25.2%), and aldehyde(18.7%) also. 2. 63% of the hospital employees replied that there were hazardous factors in hospital environments, and 80% insisted the necessity for hospital environment measuring. 35.7% of respondents replied that they had never taken the education about hazardous factors. 35.7% of the total respondents answered that they didn't use protective equipment when exposed to hazardous factors. And 48.6% answered they took periodic health examination. Only 7.2% replied that ventilation condition of office room was proper. As shown in above results, hospital employees are exposed to various hazards, and turn out neglecting to health problems caused these hazardous factors. So at first, it is necessary to measuring hospital working environment, and then will be decided the possibility of special health examination to the hospital employees.

용접공들의 면역능에 관한 연구

이수일,조봉수,김영욱,고광욱,조원근,김영실,강수용,황인경,조병만,김돈균 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.1

The authors examined human immunity indicators such as CD4, CD8, Natural Killer(NK) cell, IgG, IgA, and IgM, and heavy metals such as Pb, Cr, Cd to evaluate the health hazard of welders. We selected total 126 male subjects, 60 welders who had more than 5 year working history as an exposure group, and 66 office workers and medical college students as a control group. This immunity evaluation approach is the first newly designed study that has never been tried in past studies on welder's heath evaluation. And the results were as follows. 1. Total lymphocyte count of peripheral blood was significantly higher in welder group, 2,615±650 ea/㎕ compared with 2,368±681 ea/㎕ in control group(p>0.05). 2. The proportion of CD4, CD8, NK cell in welder group was 37.5±9.4%, 24.0±8.8%, and 21.0±9.5%, respectively, and 35.5±6.5%, 25.0±6.9%, and 19.6±8.8% in control group. CD4 and NK cell were slightly higher, and CD8 was slightly lower in welder group. but there was no statistical significance between two groups(p≥0.05). 3. IgG, IgA, and IgM in welder group were 15.9㎎/㎗, 2.7㎎/㎗ and 1.5㎎/㎗, respectively, and 15.6㎎/㎗, 2.9㎎/㎗ and 1.7㎎/㎗ in control group. There was no statistical significance between two groups(p≥0.05). 4. Blood lead, cadmium and chromium concentrations were 4.2±1.8㎍/㎗, 0.4±0.38㎍/㎗, 1.2±0.6㎍/㎗ in welder group and 3.2±1.7㎍/㎗, 0.44±0.29㎍/㎗, 1.1±0.6㎍/㎗ in control group, respectively, and these value were within normal ranges.

컴퓨터 단말기 업무자의 요통의 위험요인에 관한 연구

이철호,박정래,차애리,고광욱,김영욱,이수일 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.2

Low back pain in computer terminal operators is a very common but important symptom. While the occupational risk factors of low back pain were approved obscurely, there have been few studies on analysis or understanding of occupational risk factors. Therefore, we studied occupational risk factors of low back pain, especially for ergonomic factors as well as general characteristics of workers. We selected 98 subjects for this study, computer terminal operators ordinary using computers in Pusan. We calculated the subjective severity of low back pain of each operator by the Low Back Pain Scoring System. The relation of low back pain score to general characteristics of worker was also analyzed. We analyzed the relationship between low back pain score and individual efforts to prevent low back pain. We measured the ergonomic factors of each computer terminal operator-Trunk Inclination(TI), Arm Flexion(AF), Elbow Angle(EA), Head Tilting(HT), Knee Angle(KA), using of foot plate and gap between the popliteum and chair. The correlations between these ergonomic factors and low back pain score were then analyzed. And the results are as follows: 1. The prevalence rate of low back pain in computer terminal operators was 39.8% in this study, when low back pain score was converted by the low back pain scoring system. 2. According to general characteristics of workers related to low back pain, the scores were higher in the older age group, the married and the longer work carriers.(p<0.05) 3. In the analysis of the relationship between low back pain score and individual effort to prevent low back pain, regular exercise, history of schooling for prevention of low back pain, and declaration of intention to participate in low back pain education or exercise were stastistically significant(p<0.05). And the more severe the low back pain, the higher the intention to participate in low back pain education they had in this study. 4. In the analyses of relationships or correlations between low back pain score and each of the 7 categories of ergonomic factors, only head tilting had a weak reverse correlation with low back pain(r=0.2999, p<0.01). From now on, cohort studies for the risk factors of low back pain of workers, who have been forced to work in non-ergonomical positioning at the work site, will be necessary. On the background of these ergonomic studies, the occupational health profession should be required to manage ergonomic working conditions.

Sporadic epidermolysis bullosa simplex with a novel KRT14 mutation

( Young Wook Ko ),( Tae Lim Kim ),( Won Seon Koh ),( Jeong Eun Kim ),( Jooyeon Ko ),( Young Suck Ro ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Epidermolysis bullosa simplex (EBS) is a rare genodermatosis characterized by mechanical stress-induced blistering of the skin. Its pathogenesis is mainly associated with defects of attachment of basal keratinocytes to the underlying dermis, resulted from keratin (KRT) 5 and KRT 14 mutation. We experienced a sporadic case of EBS with a novel KRT 14 mutation. A 1-day-old female full-term newborn presented with multiple bullae and erosions mainly on hands and feet. She did not show signs of other systemic diseases. Familial history of dermatologic diseases was absent. The histopathologic examination showed intraepidermal cleft. Direct immunofluorescence finding was negative. Electromicroscopy showed that the level of cleavage was low within the basal keratinocytes, just above the level of the hemidesmosomes and keratin clumps were not observed. Additional genetic analysis by exon sequencing revealed a novel de novo heterozygous missense mutation c.369T>G (p.Asn123Lys) in KRT14 gene. On the other hand, other family members including parents and her brother did not show any abnormalities in KRT14 gene. From these findings, she was diagnosed with EBS. She is receiving conservative treatment and is being followed-up for 6 months without serious complications. Herein, we report a rare case of neonatal EBS with de novo KRT14 gene mutation, which has been only once reported in the literatures to our knowledge.

Acute Myocardial Infarction in a Young Adult during Vigorous Physical Activity

Young Youp Koh,Young Jae Ki,Sung Soo Kim,Hyun Wook Kim,Keun Ho Park,Dong Hyun Choi,Joong Wha Jeong,Kyoung Sig Chang 조선대학교 의학연구원 2017 The Medical Journal of Chosun University Vol.42 No.4

Acute myocardial infarction (AMI) as an acute form and a catastrophic manifestation of coronary artery disease (CAD) is the major cause of morbidity and mortality worldwide. The prevalence and incidence of myocardial infarction can be influenced by demographic, biological and psychosocial factors, and it is rare in childhood and adolescent years. Contrary to the elderly, where cardiac attack is mainly caused by CAD, exercise-induced cardiac attack is relatively more prevalent in a young adult. We report here on a case of ST-segment elevation myocardial infarction (STEMI) in a young adult during vigorous physical activity and we review the relevant literatures.

Scabies presenting as atypical vesicular manifestations

( Young Wook Ko ),( Tae Lim Kim ),( Won Seon Koh ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Scabies is a contagious infestation caused by the mite, Sarcoptes scabiei. The common presentations of scabies are linear burrows, pruritic papules, and inflammatory nodules. Vesicular and bullous lesions are rare in scabies. Because of its clinical and histopathologic non-specific nature, vesicular scabies may be difficult to diagnose early. We report two cases of scabies presented with vesicular lesions. A 35-year-old male with quadriplegia due to subarachnoid hemorrhage presented with multiple erythematous vesicles and pustules that appeared on his hands 2 weeks ago. Biopsy specimen from the right palm showed subcorneal blister and eosinophilic infiltration in the dermis. He treated with topical steroids for 3 months, but new inflammatory nodules and pruritic papules developed on his whole body, especially on flexural areas. Then, the KOH test was performed and scabies mites were found. Second case was a 13-year-old boy with itchy multiple vesicles on whole body which have lasted 2 months. Histopathologic examination from a vesicle of the left lower leg revealed subepidermal cleft and DIF showed negative finding. A KOH test was performed and several mites were found. After topical permethrin and oral antihistamine treatments for both patients, their skin lesions showed marked improvement. Therefore, scabies should be considered as a differential diagnosis if itchy vesicular skin lesion of unexplained etiology occurs.