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- 검색키워드
- 저자 : Seong Hee Yeo (검색결과 154 건)
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Predictions of PD-L1 Expression Based on CT Imaging Features in Lung Squamous Cell Carcinoma
Seong Hee Yeo,Hyun Jung Yoon,Injoong Kim,Yeo Jin Kim,Young Lee,Yoon Ki Cha,So Hyeon Bak 대한영상의학회 2024 대한영상의학회지 Vol.85 No.2
Purpose To develop models to predict programmed death ligand 1 (PD-L1) expression in pulmonary squamous cell carcinoma (SCC) using CT. Materials and Methods A total of 97 patients diagnosed with SCC who underwent PD-L1 expression assay were included in this study. We performed a CT analysis of the tumors using pretreatment CT images. Multiple logistic regression models were constructed to predict PD-L1 positivity in the total patient group and in the 40 advanced-stage (≥ stage IIIB) patients. The area under the receiver operating characteristic curve (AUC) was calculated for each model. Results For the total patient group, the AUC of the ‘total significant features model’ (tumor stage, tumor size, pleural nodularity, and lung metastasis) was 0.652, and that of the ‘selected feature model’ (pleural nodularity) was 0.556. For advanced-stage patients, the AUC of the ‘selected feature model’ (tumor size, pleural nodularity, pulmonary oligometastases, and absence of interstitial lung disease) was 0.897. Among these factors, pleural nodularity and pulmonary oligometastases had the highest odds ratios (8.78 and 16.35, respectively). Conclusion Our model could predict PD-L1 expression in patients with lung SCC, and pleural nodularity and pulmonary oligometastases were notable predictive CT features of PD-L1.
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생활의 질적 향상을 위한 부엌의 작업대 및 수납장에 관한 연구
김여은,김은주,김재희,김현애,김희경,성은희,옥여명,이선희,전연희,조성진 연세대학교 생활과학대학 1985 婦學 Vol.18 No.-
The purpose of this study was to examine present conditions of kitchen work centers and cabinets and to determine responses of residents in relation to them. The sample comprised of 42 households in Seoul. A questionnaire was developed, which consisted of three parts; sociodemographic information of the households, present conditions of kitchen work centers and cabinets, and their responses in relation to them. Data was analyzed by hand, using frequency and percentage. Findings from this study were as follows: 1. L shape and one wall kitchen shape were dominated, 55.0% and 32.0% respectively. The kitchen work centers were arranged most frequently in sequence of refrigerator center, sink center, mixing center, cooking center, and serving center. 2. Widths/heights of kitchen work centers and cabinets were close to the recommended measurements, however the vertical distance between the top line of kitchen work centers and the bottom line of wall cabinets showed higher than the recommended measurement. 3. Residents were satisfied to some degree with the sequence of arrangement, heights, widths, design, and color of kitchen work centers and cabinets, however they need more storage space. 4. The functional aspect and design were the major factors influenced residents' decision making for the buying behavior of the kitchen work centers and cabinets.
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여성희 ( Seong Hee Yeo ),이해종 ( Hae Jong Lee ),서영준 ( Young Joon Seo ),김영훈 ( Young Hoon Kim ) 한국병원경영학회 2009 병원경영학회지 Vol.14 No.3
The purpose of this study was to provide criteria which help executives to make decisions through the analysis of profitability of ultrasonography conducted in each medical department. In order to achieve such purpose, the study conducted break-even analyses on three medical departments of a university hospital in which has used ultrasonography was largely conducted in diagnosing diseases and performing surgeries. The research was carried out from January to June 2008. The data necessary for calculating cost, were collected using by computerized data. The results of the study were summarized as follows. 1. The Cost structure of each medical department. The Cost of ultrasonography was divided into direct cost and indirect cost through the categorization by cost object. Labor cost accounted for the largest portion of the direct cost with 69.3% in the department of obstetrics and gynecology, 67.4% in the department of radiology and 58.2% in the cardiac ultrasonography center, which followed by the depreciation cost of ultrasonography equipment. The calculation of the average material cost of each ultrasonographic test by medical test found that the cardiac ultrasonography center took first place with 2,355 won, followed by the department of obstetrics and gynecology with 266 won and the department of radiology with 233 won. As for the power cost of ultrasonography equipment, the department of radiology took fist place with 442,000 won. The power cost, however, did not affect much the cost price, because it accounted for only a small portion of the cost. As for indirect cost, the cardiac ultrasonography center ranked first with 7,156,000 won. Building depreciation cost accounted for the largest portion of the indirect cost. 2. Break-even analysis. Under the supposition that cost price can be divided into fixed cost and variable cost, a break-even analysis was conducted using the cost price confirmed through the cost structure of each medical department. As for the average customary charge of ultrasonography test conducted in each medical department, the department of obstetrics and gynecology charged 24,627 won, the department of radiology 53,179 won and the cardiac ultrasonography center 65,174 won. According to these results, the charges of ultrasonography test imposed by the department of radiology and the cardiac ultrasonography center wre enough to surpass break-even levels, but the charge imposed by the department of obstetrics and gynecology was not enough to offset the cost price. In conclusion, labor cost accounted for the largest proportion of cost price of ultrasonography test conducted in diagnosing diseases and performing surgeries in medical departments, followed by the fixed cost of ultrasonographic equipment depreciation cost. In medical department where the current charge of ultrasonography test turned out not to offset cost price through the break-even analysis of ultrasonographic equipment, ways to reduce fixed cost which accounts for the largest proportion of the cost price should be sought. Even medical departments whose current charge of ultrasonography test is enough to surpass break-even level are required to work for efficient management and cost reduction to continuously generate profits.
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Seong-Hee Kim,박지영,Ji-Youl Jung,김하영,Yu-Ri Park,Kyoung-Ki Lee,Young S. Lyoo,Sang-Geon Yeo,Choi-Kyu Park 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.5
A novel porcine circovirus 3 (PCV3) was first detected in pigs showing porcine dermatitis and nephropathy syndrome, reproductive failure, and multisystemic inflammation in the USA. Herein, we report on PCV3 as a potential etiological agent of clinical signs, reproductive failure and respiratory distress on Korean pig farms, based on in situ hybridization, pathological, and molecular findings. Confirmation of the presence of PCV3 may increase co-infection with other causative agents of disease in Korean pig herds, indicating the need for further systemic investigation of pathogenicity and of multiple infections with PCV2 genotypes and bacteria, and the development of an effective PCV3 vaccine.
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( Seong Hoon Yoon ),( Byung Hee Lee ),( Hye Ju Yeo ),( Dong Wan Kim ),( Seung Eun Lee ),( Woo Hyun Cho ),( Doo Soo Jeon ),( Yun Seong Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: With the implementation of liquid culture methods, the yield of mycobacterial culture from pleural fi uid has become much higher than previously reported. However, few studies have directly compared the performance of liquid and solid media from pleural fi uid, and it is still uncertain whether liquid culture media could replace solid media in pleural effusion culture. Methods: We retrospectively compared the culture yield, time to positivity, and contamination rate of the BACTEC Mycobacteria Growth Indicator Tube 960 (MGIT) and Ogawa meida from pleural fi uid in consecutive patients diagnosed with tuberculous pleurisy. Results: Of 104 patients, 43 (41.3%) were positive on either the MIGIT or the Ogawamedia. The culture yield of MIGIT was higher (40.4%, 42/104) than of that of Ogawa media (18.3%, 19/104) (P < 0.001). Only one patient was positive on the Ogawa medium only. The median time to positivity was faster in the MGIT (18 days, range 8-32) than in the Ogawa media (37, 20-59) (P< 0.001). There was no contamination on both culture media.Conclusions: The use of liquid culture media of the pleural fi uid can provide higher yields and faster results than solid media. Supplemental solid media may have little effect in increasing the culture yield from pleural fi uid.
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NEWTON-RAPHSON METHOD FOR COMPUTING p-ADIC ROOTS
Yeo, Gwangoo,Park, Seong-Jin,Kim, Young-Hee Chungcheong Mathematical Society 2015 충청수학회지 Vol.28 No.4
The Newton-Raphson method is used to compute the q-th roots of a p-adic number for a prime number q. The sufficient conditions for the convergence of this method are obtained. The speed of its convergence and the number of iterations to obtain a number of corrected digits in the approximation are calculated.
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Yeo Sung Yoon,Eun Sung Park,Seong Joon YI,Jin Sang Kim,이흥식,In Se Lee,Je Kyung Seong,Hee Kyung Jin 대한수의학회 2004 Journal of Veterinary Science Vol.5 No.4
This study was aimed to investigate the changes of orexin-A (OXA) and neuropeptide Y (NPY) expression in the hypothalamus of the fasted and high-fat diet fed rats. For the experiments, the male Sprague-Dawley (SD) rats were used as the model of high-fat diet-induced obesity. The mean loss of body weight (MLBW) did not show the linear pattern during the fasting; from 24 h to 84 h of fastings, the MLBW was not significantly changed. The numbers of OXA-immunoreactive (IR) neurons were decreased at 84 h of fasting compared with those in other five fasting subgroups. The NPY immunoreactivities in the arcuate nucleus (ARC) and the suprachiasmatic nucleus (SCN) observed at 84 h of fasting were higher than that observed at 24 h of fasting. The number of OXA-IR neurons of the LHA (lateral hypothalamic area) in the high-fat (HF) diet fed group was more increased than that of the same area in the normal-fat (NF) diet fed group. The NPY immunoreactivities of the ARC and the SCN were higher in HF group than those observed in the same areas of NF group. Based on these results, it is noteworthy that the decrease of the body weight during the fast was not proportionate to the time-course, implicating a possible adaptation of the body for survival against starvation. The HF diet might activate the OXA and the NPY in the LHA to enhance food intake. This study was aimed to investigate the changes of orexin-A (OXA) and neuropeptide Y (NPY) expression in the hypothalamus of the fasted and high-fat diet fed rats. For the experiments, the male Sprague-Dawley (SD) rats were used as the model of high-fat diet-induced obesity. The mean loss of body weight (MLBW) did not show the linear pattern during the fasting; from 24 h to 84 h of fastings, the MLBW was not significantly changed. The numbers of OXA-immunoreactive (IR) neurons were decreased at 84 h of fasting compared with those in other five fasting subgroups. The NPY immunoreactivities in the arcuate nucleus (ARC) and the suprachiasmatic nucleus (SCN) observed at 84 h of fasting were higher than that observed at 24 h of fasting. The number of OXA-IR neurons of the LHA (lateral hypothalamic area) in the high-fat (HF) diet fed group was more increased than that of the same area in the normal-fat (NF) diet fed group. The NPY immunoreactivities of the ARC and the SCN were higher in HF group than those observed in the same areas of NF group. Based on these results, it is noteworthy that the decrease of the body weight during the fast was not proportionate to the time-course, implicating a possible adaptation of the body for survival against starvation. The HF diet might activate the OXA and the NPY in the LHA to enhance food intake.
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( Yeo-ok Park ),( Hee-jeong Jae ),( Ji-young Shon ),( Seong-tae Choi ),( Sung-chul Kim ),( Yong-cho Cho ),( Kwang-pyo Hong ),( Younghoon Park ) 한국육종학회 2016 Plant Breeding and Biotechnology Vol.4 No.3
Persimmon (Diospyros kaki Thunb.) is classified into four types based on the fruit traits, astringency and flesh color. Of the four types, the pollination-constant non-astringent (PCNA) fruit is typically most desirable for consumption. In the present study, we used five sequence characterized amplified region (SCAR) markers associated with astringency in persimmon fruit, namely E4/E9r, E4/A2r, 7H9F/AST-R, AST-F/AST-R, and AST-F/PCNA-F/5R3R, to improve the efficiency of PCNA-type persimmon breeding via marker-assisted selection (MAS). A total of 84 cultivars of the four types and their segregating F1 progeny were used to evaluate the association of SCAR markers with the fruit astringency phenotype. Polymerase chain reaction evaluation of each SCAR marker showed that E4/E9r combined with AST-F/PCNA-F/5R3R was appropriate for selecting the ast allele responsible for PCNA-type fruit, as the phenotype-genotype match percentages of these two markers were 94% and 99%, respectively. This MAS was verified by the successful use of AST-F/PCNA-F/5R3R to select 107 PCNA-type individuals from 609 F1 hybrid progeny derived from various crosses.
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