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      • Biochar-supported nZVI (nZVI/BC) for contaminant removal from soil and water: A critical review

        Wang, Shengsen,Zhao, Mingyue,Zhou, Min,Li, Yuncong C.,Wang, Jun,Gao, Bin,Sato, Shinjiro,Feng, Ke,Yin, Weiqin,Igalavithana, Avanthi Deshani,Oleszczuk, Patryk,Wang, Xiaozhi,Ok, Yong Sik Elsevier 2019 Journal of hazardous materials Vol.373 No.-

        <P><B>Abstract</B></P> <P>The promising characteristics of nanoscale zero-valent iron (nZVI) have not been fully exploited owing to intrinsic limitations. Carbon-enriched biochar (BC) has been widely used to overcome the limitations of nZVI and improve its reaction with environmental pollutants. This work reviews the preparation of nZVI/BC nanocomposites; the effects of BC as a supporting matrix on the nZVI crystallite size, dispersion, and oxidation and electron transfer capacity; and its interaction mechanisms with contaminants. The literature review suggests that the properties and preparation conditions of BC (e.g., pore structure, functional groups, feedstock composition, and pyrogenic temperature) play important roles in the manipulation of nZVI properties. This review discusses the interactions of nZVI/BC composites with heavy metals, nitrates, and organic compounds in soil and water. Overall, BC contributes to the removal of contaminants because it can attenuate contaminants on the surface of nZVI/BC; it also enhances electron transfer from nZVI to target contaminants owing to its good electrical conductivity and improves the crystallite size and dispersion of nZVI. This review is intended to provide insights into methods of optimizing nZVI/BC synthesis and maximizing the efficiency of nZVI in environmental cleanup.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Aggregation and passivation of nZVI can be alleviated by surfactants and doping methods. </LI> <LI> BC hinders corrosion and improves the dispersion and electron transfer of nZVI. </LI> <LI> Properties of nZVI depend on those of the BC, feedstock and pyrogenic temperature. </LI> <LI> BC enhances electron transfer from nZVI to the contaminants due to the presence of quinone and graphene moieties. </LI> <LI> nZVI/BC shows strong ability to remove HMs, nitrates, and organic contaminants in soil and water. </LI> </UL> </P>

      • Security Threats among DICOM Imaging Communications in Public Networks

        Feng Zhou,Zhongqi Zhang,Jin Wang,Bin Li,Jeong-Uk Kim 보안공학연구지원센터 2014 International Journal of Future Generation Communi Vol.7 No.6

        Picture archiving and communication systems (PACS) require high-speed networks to transmit large image files between components. Image-data transmission from one site to another through public network is usually characterized in term of privacy, authenticity, and integrity. However, public network’s security issues had always been the significant problems. Recent years, IPv6 brings significant improvements in mechanisms for assuring a higher level of security and confidentiality of the transmitted information. Thus, it is still necessary to take care of some particular aspects. In this paper, we first analyzes how actual security threats and different types of attacks affect IPv6 networks while transmitting Digital Imaging and Communications in Medicine (DICOM) files through the public Internet. Second, illustrate some shortcomings of IPv6 and IPv6’s traffic loads. Finally, some possible solutions against a number of security threats in IPv6 DICOM files transmitting networks have been given.

      • KCI등재

        An integrated porous Ni3S2 electrode assisted by copper with advanced performance for sodium storage

        Li-Feng Zhou,He Gong,Yisong Wang,He Jia,Li-Ying Liu,Tao Du 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.111 No.-

        Sodium ion battery has been rapidly consolidating its status of the dominant power supplier for largescaleenergy storage systems as a candidate of lithium ion battery and has gotten widely attention. In thiswork, an integrated porous Ni3S2 electrode assisted by copper using for sodium storage showed anadvanced electrochemical performance and long life-span. Coupled with Cu particles planted on the surfaceof Ni foam, electron transfer can be fast induced, thus avoiding the electrode damage due to collectionelectron. It further achieved a superior retention of 88.7 % with the capacity of 417 mAh g1. In thekinetics analysis, the capacitance-controlled capacity in the electrochemical process dominated, and thefast calculated Na+ diffusion coefficients was 4 10-10 cm2 s1. Therefore, it deserves attention and furtherresearch for the commercial application of large-scale energy storage.

      • KCI등재

        A novel M2e-multiple antigenic peptide providing heterologous protection in mice

        Feng Wen,Ji-Hong Ma,Hai Yu,Fu-Ru Yang,Meng Huang,Yan-Jun Zhou,Ze-Jun Li,Xiu-Hui Wang,Guo-Xin Li,Yi-Feng Jiang,Wu Tong,Guangzhi Tong 대한수의학회 2016 Journal of Veterinary Science Vol.17 No.1

        Swine influenza viruses (SwIVs) cause considerable morbidity and mortality in domestic pigs, resulting in a significant economic burden. Moreover, pigs have been considered to be a possible mixing vessel in which novel strains loom. Here, we developed and evaluated a novel M2e-multiple antigenic peptide (M2e-MAP) as a supplemental antigen for inactivated H3N2 vaccine to provide cross-protection against two main subtypes of SwIVs, H1N1 and H3N2. The novel tetra-branched MAP was constructed by fusing four copies of M2e to one copy of foreign T helper cell epitopes. A high-yield reassortant H3N2 virus was generated by plasmid based reverse genetics. The efficacy of the novel H3N2 inactivated vaccines with or without M2e-MAP supplementation was evaluated in a mouse model. M2e-MAP conjugated vaccine induced strong antibody responses in mice. Complete protection against the heterologous swine H1N1 virus was observed in mice vaccinated with M2e-MAP combined vaccine. Moreover, this novel peptide confers protection against lethal challenge of A/Puerto Rico/8/34 (H1N1). Taken together, our results suggest the combined immunization of reassortant inactivated H3N2 vaccine and the novel M2e-MAP provided cross-protection against swine and human viruses and may serve as a promising approach for influenza vaccine development.

      • KCI등재

        Reduction in SBPase Activity by Antisense RNA in Transgenic Rice Plants: Effect on Photosynthesis, Growth, and Biomass Allocation at Different Nitrogen Levels

        Lingling Feng,Hui Li,Jingmei Jiao,Ding Li,Li Zhou,Jian Wan,Yangsheng Li 한국식물학회 2009 Journal of Plant Biology Vol.52 No.5

        Rice cultivar zhonghua11 (Oryza sativa L. ssp. japonica) plants with decreased sedoheptulose-1, 7- bisphosphatase (SBPase) were obtained by transformation with the rice SBPase antisense gene under the control of the maize ubiquitin promoter. The transgenic and wild-type plants were grown at different nitrogen levels (0.1, 1, or 10 mM NH4NO3). Growth rates of the seedlings were measured by the changes in dry weight, and the photosynthetic carbon reduction activities and the potential efficiency of photosystem II were measured by CO2 assimilation and Fv/Fm, respectively. At low N, there are strong effects on growth and photosynthesis when SBPase was reduced by genetic manipulation. Decreased SBPase activity led to a decrease in the amount of starch accumulated in the leaves at all N levels and the decrease was much more prominent in low N than that in high N, but the starch allocation between shoot and root was unaltered. The analysis of chlorophyll fluorescence and SBPase activity indicated that the decrease of growth and photosynthesis at different N levels were not related to the function of PSII but to the activity of SBPase. Western blot analysis showed the content of SBPase in thylakoid membranes was much more than in the stroma fractions in transgenic plants at low N. Results suggested that low N in addition to a 34% decrease in SBPase activity is sufficient to diminish photosynthesis and limit biomass production. Decreased SBPase activity may reduce the N use efficiency of photosynthesis and growth and alter biomass allocation.

      • KCI등재

        IRE1α protects against osteoarthritis by regulating progranulin-dependent XBP1 splicing and collagen homeostasis

        Liang Li,Zhang Fengmei,Feng Naibo,Kuang Biao,Fan Mengtian,Chen Cheng,Pan Yiming,Zhou Pengfei,Geng Nana,Li Xingyue,Xian Menglin,Deng Lin,Li Xiaoli,Kuang Liang,Luo Fengtao,Tan Qiaoyan,Xie Yangli,Guo Fen 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        Osteoarthritis (OA) is a full-joint, multifactorial, degenerative and inflammatory disease that seriously affects the quality of life of patients due to its disabling and pain-causing properties. ER stress has been reported to be closely related to the progression of OA. The inositol-requiring enzyme 1α/X-box-binding protein-1 spliced (IRE1α/XBP1s) pathway, which is highly expressed in the chondrocytes of OA patients, promotes the degradation and refolding of abnormal proteins during ER stress and maintains the stability of the ER environment of chondrocytes, but its function and the underlying mechanisms of how it contributes to the progression of OA remain unclear. This study investigates the role of IRE1α/ERN1 in OA. Specific deficiency of ERN1 in chondrocytes spontaneously resulted in OA-like cartilage destruction and accelerated OA progression in a surgically induced arthritis model. Local delivery of AdERN1 relieved degradation of the cartilage matrix and prevented OA development in an ACLT-mediated model. Mechanistically, progranulin (PGRN), an intracellular chaperone, binds to IRE1α, promoting its phosphorylation and splicing of XBP1u to generate XBP1s. XBP1s protects articular cartilage through TNF-α/ERK1/2 signaling and further maintains collagen homeostasis by regulating type II collagen expression. The chondroprotective effect of IRE1α/ERN1 is dependent on PGRN and XBP1s splicing. ERN1 deficiency accelerated cartilage degeneration in OA by reducing PGRN expression and XBP1s splicing, subsequently decreasing collagen II expression and triggering collagen structural abnormalities and an imbalance in collagen homeostasis. This study provides new insights into OA pathogenesis and the UPR and suggests that IRE1α/ERN1 may serve as a potential target for the treatment of joint degenerative diseases, including OA.

      • Anti-metastasis Activity of Black Rice Anthocyanins Against Breast Cancer: Analyses Using an ErbB2 Positive Breast Cancer Cell Line and Tumoral Xenograft Model

        Luo, Li-Ping,Han, Bin,Yu, Xiao-Ping,Chen, Xiang-Yan,Zhou, Jie,Chen, Wei,Zhu, Yan-Feng,Peng, Xiao-Li,Zou, Qiang,Li, Sui-Yan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

        Background: Increasing evidence from animal, epidemiological and clinical investigations suggest that dietary anthocyanins have potential to prevent chronic diseases, including cancers. It is also noteworthy that human epidermal growth factor receptor 2 (ErbB2) protein overexpression or ErbB2 gene amplification has been included as an indicator for metastasis and higher risk of recurrence for breast cancer. Materials and Methods: The present experiments investigated the anti-metastasis effects of black rice anthocyanins (BRACs) on ErbB2 positive breast cancer cells in vivo and in vitro. Results: Oral administration of BRACs (150 mg/kg/day) reduced transplanted tumor growth, inhibited pulmonary metastasis, and decreased lung tumor nodules in BALB/c nude mice bearing ErbB2 positive breast cancer cell MDA-MB-453 xenografts. The capacity for migration, adhesion, motility and invasion was also inhibited by BRACs in MDA-MB-453 cells in a concentration dependent manner, accompanied by decreased activity of a transfer promoting factor, urokinase-type plasminogen activator (u-PA). Conclusions: Together, our results indicated that BRACs possess anti-metastasis potential against ErbB2 positive human breast cancer cells in vivo and in vitro through inhibition of metastasis promoting molecules.

      • KCI등재

        Human Intersectin 2 (ITSN2) binds to Eps8 protein and enhances its degradation

        ( Xiao Feng Ding ),( Zijian Yang ),( Fang Liang Zhou ),( Xiang Huchang ),( Zhou Chang Luo ),( Zhi Cheng He ),( Qian Liu ),( Hong Li ),( Feng Yan ),( Fang Mei Wang ),( Shuang Lin Xiang ),( Jian Zhang ) 생화학분자생물학회 (구 한국생화학분자생물학회) 2012 BMB Reports Vol.45 No.3

        Participates in actin remodeling through Rac and receptor endocytosis via Rab5. Here, we used yeast two-hybrid system with Eps8 as bait to screen a human brain cDNA library. ITSN2 was identified as the novel binding factor of Eps8. The interaction between ITSN2 and Eps8 was demonstrated by the in vivo co-immunoprecipitation and colocalization assays and the in vitro GST pull-down assays. Furthermore, we mapped the interaction domains to the region between amino acids 260-306 of Eps8 and the coiled-coil domain of ITSN2. In addition, protein stability assays and immunofluorescence analysis showed ITSN2 overexpression induced the degradation of Eps8 proteins, which was markedly alleviated with the lysosome inhibitor NH4Cl treatment. Taken together, our results suggested ITSN2 interacts with Eps8 and stimulates the degradation of Eps8 proteins. [BMB reports 2012; 45(3): 183-188]

      • KCI등재

        Effect of nano-carbon addition on color performance of polystyrene superstructure film

        Ye-min ZHOU,Li-li Wang,Xiao-peng LI,Xiu-feng Wang,Hong-tao JIANG 한양대학교 세라믹연구소 2018 Journal of Ceramic Processing Research Vol.19 No.6

        Polystyrene superstructure films show faint rainbow color, and this low color saturation limits its wide application. In thispaper, polystyrene superstructure films with single bright blue color were prepared by vertical deposition self-assemblymethod using polystyrene microspheres with average diameter of 310 ± 10 nm as raw material. Polystyrene superstructurefilms were modified by adding nano-carbon powder, and effect of the amount of nano-carbon powde on color performancewas studied. The results showed that without addition of nano-carbon powder, the superstructure films showed a faint rainbowcolor, while with addition of nano-carbon power, the superstructure films exhibited a single bright blue under the same naturallight source. Changing the amount of nano-carbon powder addition could adjust color saturation of the film. With increasingthe amount of nano-carbon powder addition from 0.008 wt% to 0.01 wt%, color saturation of the superstructure filmincreased gradually. Further increasing the amount of nano-carbon powder addition to 0.011wt%, color saturation of thesuperstructure film didn’t increase anymore and tended to get dark.

      • KCI등재

        The potential molecular effects of bursal septpeptide II on immune induction and antitumor activity

        Guang Fang Zhou,Qing Tao Liu,Bin Zhou,Ya Feng Qiu,Xiao Dong Liu,Zhi Yong Ma,Xiu Li Feng,Rui Bing Cao,Pu Yan Chen 대한수의학회 2015 Journal of Veterinary Science Vol.16 No.3

        The bursa of Fabricius (BF) is the acknowledged central humoral immune organ in birds. Bursal septpeptide II (BSP-II) is animmunomodulatory bioactive peptide isolated from BF. To understand the effects of BSP-II on immune induction, gene expression profilesof hybridoma cells treated with BSP-II were evaluated. Pathway analysis showed that regulated genes were involved in cytokine-cytokinereceptor interactions, T cell receptor signaling pathway, and pathway in cancer. It was observed that BSP-II reduced tumor cells proliferationand stimulated p53 expression. These results indicate potential mechanisms underlying the effects of the humoral immune system on immuneinduction, including antitumor activities. Our study has provided a novel insight into immunotherapeutic strategies for treating human tumors.

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