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- 저자 : Kyunghoon Kim (검색결과 419 건)
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Kim, Su-Jung,Kim, Hong-Gyum,Kim, Byung-Chul,Kim, Kyunghoon,Park, Eun-Hee,Lim, Chang-Jin The Microbiological Society of Korea 2004 The journal of microbiology Vol.42 No.3
Transcriptional regulation of the Schizosaccharomyces pombe y-glutamylcysteine synthetase (GCS) gene was examined using the two GCS-lacZ fusion plasmids pUGCS101 and pUGCS102, which harbor 607 bp and 447 bp upstream regions, respectively. The negatively-acting sequence was located in the -607 - -447 bp upstream region of the GCS gene. The upstream sequence responsible for induction by menadione(MD) and L-buthionine-(S, R)-sulfoximine (BSO) resides in the -607 - -447 bp region, whereas the sequence which codes for nitric oxide induction is located within the -447 bp region, measured from the translational initiation point. Carbon source-dependent regulation of the GCS gene appeared to be dependent on the nucleotide sequence within -447 bp region. The transcription factor Papl is involved in the induction of the GCS gene by MD and BSO, but not by nitric oxide. Induction of the GCS gene occurring due to low glucose concentration does not depend on the presence of Pap1. These data imply that induction by MD and BSO may be mediated by the Pap1 binding site, probably located in the -607 - -447 region, and also that the nitric oxide-mediated regulation of the S. pombe GCS gene may share a similar mechanism with its carbon-dependent induction.
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Kim Beom Joon,Choi Arum,Kim Hwan Soo,Oh Jin-Hee,Lee Jae-Young,Kim Sukil,Han Ji-Whan,Kim Kyunghoon,Kim Hyun Hee 대한의학회 2022 Journal of Korean medical science Vol.37 No.20
Background: The impact of the coronavirus disease 2019 (COVID-19) pandemic on Kawasaki disease (KD) has not yet been established. We investigated changes in the observed number and severity of KD cases and accompanying coronary artery complications during the COVID-19 pandemic in Korea. Methods: This retrospective observational study included patients aged < 18 years with acute-phase KD diagnosed between March 2018 and February 2021. Data were extracted from the Clinical Data Warehouse that houses data from five affiliated university hospitals in Korea. We analyzed changes in the number of patient admissions and clinical characteristics, including cardiac complications, before and after the onset of the COVID-19 pandemic. Results: A total of 475 admissions were included in the analysis. After March 2020, we observed a significant decrease of 33% in the number of hospitalizations for KD compared with the average number of hospitalizations during the previous 2 years. The number of admissions per month significantly decreased by 7.9 persons/month (95% confidence interval, −13.8 to −2.0; P < 0.05) compared with that before COVID-19. By contrast, the proportion of patients aged < 1 year with KD increased. The proportion of patients with refractory KD and the rate of cardiac complications did not change significantly. Conclusion: Since the onset of the COVID-19 pandemic, the total number of hospital admissions for KD has decreased in Korea. Although the proportion of admissions of infants aged < 1 year increased, no changes were observed in clinical courses and complications.
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도로변 초미세먼지의 실시간 질량농도 및 부피농도 측정을 이용한 시간별 밀도 분석-광흡수 eBC에 대한 OPS 보정 중심
김은영(Eunyoung Kim),서석준(Seokjun Seo),김선문(Sunmoon Kim),정성운(Sungwoon Jung),이용민(Yongmin Lee),오세호(Sea-Ho Oh),박규태(Gyutae Park),김경훈(Kyunghoon Kim),김정화(Jounghwa Kim),홍유덕(Youdeog Hong),이태형(Taehyoung Lee),배민석(Mi 한국대기환경학회 2018 한국대기환경학회지 Vol.34 No.6
This study investigated the effective density of ambient fine particulate matter (PM<SUB>2.5</SUB>) and from July 28 to August 7 of 2018 at the road side in Seoul. Beta-ray Attenucation Monitor (BAM), Scanning Mobility Particle Sizer (SMPS), Optical Particle Sizer (OPS), and Muliti Angle Absorption Photometers (MAAP) have been utilized for PM<SUB>2.5</SUB> mass and PM<SUB>2.5</SUB> volume concentrations. The equivalent Black Carbon (eBC) from MAAP has been reconstructed to PM<SUB>0.3-2.5</SUB> eBC volume concentrations from mass absorption cross-section (MAC) compared to thermal elemental carbon. The six-hour average of effective density was ranged from 1.06 to 1.79 g/cm³. The diurnal variation of effective density was pronounced for the source impact related to PM chemical components. The overall average of density has been determined as 1.27 g/cm³ in this study. This study provides insight into the physical and chemical aspects of atmospheric particulate matter related to sources and design of control system.
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Engineering nanowrinkled microfibers composed of eggshell membrane and graphene
Park, Sunho,Choi, Kyoung Soon,Kim, Woochan,Lee, Dohyeon,Kim, Daun,Kim, Myung-Sun,Kim, Kyunghoon,Kim, Jangho Elsevier 2018 Materials letters Vol.229 No.-
<P><B>Abstract</B></P> <P>We present a facile method for designing and manipulating eggshell membrane-based nanowrinkled microfibers (EMNMs) using graphene and a spin-coating technique. Graphene is simply spin-coated on the eggshell membrane to form multiscale structures of nanowrinkled microfibers. We demonstrate that the EMNMs combine the unique properties of the raw eggshell membrane and graphene, such as micro- and nanoscale hierarchical morphologies, specific crystalline structures, and surface wettability. We also show that the properties of the EMNMs can be controlled by adjusting the concentration of graphene.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Nanowrinkled microfibers composed of eggshell membrane and graphene are fabricated. </LI> <LI> The properties of the prepared nanowrinkled microfibers are investigated. </LI> <LI> The microfiber properties can be controlled by adjusting the graphene concentration. </LI> </UL> </P>
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Novel Beamforming and User Scheduling Algorithm for Inter-cell Interference Cancellation
Kyunghoon Kim,Jinhua Piao,Seungwon Choi 대한전자공학회 2016 IEIE Transactions on Smart Processing & Computing Vol.5 No.5
Coordinated multi-point transmission is a candidate technique for next-generation cellular communications systems. We consider a system with multiple cells in which base stations coordinate with each other by sharing user channel state information, which mitigates inter-cell interference (ICI), especially for users located at the cell edge. We introduce a new user scheduling method that considers both ICI and intra-cell orthogonality. Due to the influence of ICI cancellation and the loss reduction of effective channel gain during the beamforming process, the proposed method improves the system sum rate, when compared to the conventional method, by an average of 0.55bps/Hz for different numbers of total users per cell.
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Kim, Jin Woo,Kim, Yeonjoon,Baek, Kyung Yup,Lee, Kyunghoon,Kim, Woo Youn American Chemical Society [etc.] 2019 The Journal of physical chemistry A Vol. No.
<P>Accurate analysis of complex chemical reaction networks is necessary for reliable prediction of reaction mechanism. Though quantum chemical methods provide a desirable accuracy, large computational costs are unavoidable as considering numerous reaction pathways on the networks. We proposed a graph-theoretic approach combined with chemical heuristics (named ACE-Reaction) in previous work [<I>Chem. Sci.</I>2018, 9, 825], which automatically and rapidly finds out the most essential part of reaction networks just from reactants and products, and here we extended it by incorporating a stochastic approach for microkinetic modeling. To show its performance and broad applicability, we applied it to 26 organic reactions, which include 16 common functional groups. As a result, we could demonstrate that ACE-Reaction successfully found the accepted mechanism of all reactions, most within a few hours on a single workstation, and additional microkinetic modeling automatically discovered new competitive paths as well as a major path.</P> [FIG OMISSION]</BR>
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