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양 족부 열감을 호소하는 하지불안증후군 환자 치험 1례
김경묵,서원주,김수빈,정우상,문상관,권승원,조기호,Kim, Gyeong-muk,Suh, Won-joo,Kim, Su-bin,Jung, Woo-sang,Mun, Sang-kwan,Kwon, Seung-won,Cho, Ki-ho 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.2
Objectives: The purpose of this study is to evaluate the effectiveness of electroacupuncture on heat sensation of the feet of a 61-year-old female patient with restless leg syndrome. Methods: Electroacupuncture was performed at four acupoints (KI3 (太谿), KI6 (照海), LR3 (太衝), LR2 (行間)) selected to reduce heat sensation in both feet. The patient's symptoms were assessed using the VAS (Visual Analogue Scale), the SF-MPQ (short-form McGill Pain Questionnaire), and the IRLS (International Restless Legs Scale). The treatment was performed from April 20, 2010 to April 24, 2010. Results: During five sessions of electroacupuncture treatments, the VAS, SF-MPQ, and IRLS scores improved throughout the treatment period and afterwards. Conclusions: The results suggest that electroacupuncture at KI3(太谿), KI6(照海), LR3(太衝), LR2(行間) can be effective for reducing hot flush in both feet.
2-Cinnamoyl thiophene의 가수분해 반응메카니즘
권기성,맹주양,박천규 충남대학교 1985 忠南科學硏究誌 Vol.12 No.2
The rate constants for the hydrolysis of 2-cinnamoylthiophene were determined by UV spectrophotometry in 50% methanol-water at 29℃ and a rate equation which can be applied over wide pH range was obtained. From this equation, we may conclude the following: above pH12, the over-all rate is only dependent on the concentration of hydroxide ion and below pH 10, the reaction is initiated by the attack of water molecule on the activated carbon-carbon double bond. In the range of pH from 10 to 12, these two reactions occur competitively.
권경주,정성애,심기남,정정화,강석형,송도경,전승정,김혜인 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.1
Until recently, colorectal polyps were classified predominantly as hyperplastic or adenomatous. While adenomatous polyps are well-characterized precursor lesions of adenocarcinomas, hyperplastic polyps have been considered as benign lesion. However, some hyperplastic polyps with serrated morphology of the crypts have been recognized to have distinctive features and these polyps were termed ‘serrated adenomas’. Recent data show that sessile serrated adenomas (SSA) might be the precursors of serrated colonic cancers, underlining the necessity of identifying them. SSA is approximately 3% of all polyps, commonly appears as flat or sessile and yellowish due to mucus production. In the pathogenesis of SSA, progression to high grade dysplasia or early invasive carcinoma may be associated with serrated neoplasia pathway different from adenoma-carcinoma sequence. We report a case with a colon polyp diagnosed as sessile serrated adenoma with high grade dysplasia after endoscopic submucosal dissection.
Cinnamonitrile 에 대한 Hydrogen Cyanide의 친핵성 첨가반응 메카니즘 연구(第 1 報)
孟柱恨,鄭昌雄,權奇星 순천향대학교 1981 논문집 Vol.4 No.1
The rate constants of the nucleophilic addition reaction of hydrogen cyanide to cinnam onitrile were determined by uv spectrophotometry at various pH and a rate equation which can Be applid over wide pH range was obtained. Below pH 9.50, the nucleophilic addition reaction of hydrogen cyanide to cinnamonitrile is initiated by the attack of hydrogen cyanide molecule on the activated carbon-carbon doub1e bond. Above pH 11. 5O, cyanide ion is the only nucleophile to cinnamonitrile, and in the range of pH from 9.50 to 11.50, these two reactions occur competitively. In strong alkaline solution. i,e. above pH 13.0, Michael type of nucleophilic addition proceeded completely.
4-Nitrostyrylphenylsulfone의 加水分解反應 메카니즘과 그의 反應速度論的 硏究
맹주양,권기성 순천향의과대학 1979 Journal of Soonchunhyang Medical Science Vol.2 No.1
The rate constants for the hydrolysis of 4-Nitrostyryl-phenylsulfone were determined by UV spectrophotometer in 50% methanol-water at 29℃ and a rate equation which can be applied overwide pH range was obtained. From this equation, we may conclude the following; above pH 12, the over-all rate is only dependent on the concentration of hydroxide ion and below pH 9.5, the reaction is initiated by the attack of a water molcule on the activated carbon-carbon double bond. In the range of pH from 9.5 to 12, these two reactions occur competitively.
심기남,정성애,주양희,유권 이화여자대학교 의과대학 2005 EMJ (Ewha medical journal) Vol.28 No.2
목적: 본 연구는 암의 침윤과 전이에 필수적인 기질단백분해효소(matrix metalloproteinases, MMPs)와 억제인자(tissue inhibitor of metalloproteinase, TIMPs)의 발현정도를 위암의 생검조직에서 확인하고 임상적, 병리학적 소견과의 상관관계를 분석하여 임상적 유용성을 평가하고자 하였다. 방법: 2003년 8월부터 2004년 7월까지 본원에서 위암으로 진단되어 근치적 치료를 받은 30명의 환자를 대상으로 하였다. 조직은 위내시경 검사시 정상 점막 및 암으로 진단한 병변에서 생검겸자를 이용하여 얻었다. 역전사중합효소연쇄반응(RT-PCR)을 이용하여, 정상조직을 기준으로 암조직에서의 MMP-W, MMP-9, MT1-MMP, TIMP-1, TIMP-2의 발현정도를 반정량법으로 비교하였다. 결과: MT1-MMP의 발현정도는 위암의 분화도, 림프혈관계 침윤, 림프절 전이 및 암의 병기와 유의한 상관관계가 있었다.(p<0.05). 그 외의 MMP-2, MMP-9, TIMP-1,TIMP-2의 발현은 임상적 소견과 유의한 관계를 보이지않았다. 결론: 반정량적 역전사중합효소연쇄반응을 이용하여 MT1-MMP의 발현 증가 유무를 확인하는 것은 위암의 공격적 특성을 예측하는데 유용할 것으로 생각되며, 이러한 검사는 수술 전에 얻어진 생검조직을 이용하여 가능하므로 암의 공격성에대한 정보를 수술 전에제공할 수 있을 것으로 사료된다.