Comparison of the community structure and changes of ground beetle (Coleoptera: Carabidae) as indicator species in forest genetic resource reserve

Myeong–Ho Kim,Min-Chul Kim,Seung-Gyu Lee,Il-Kwon Kim 한국응용곤충학회 2018 한국응용곤충학회 학술대회논문집 Vol.2018 No.04

2016년도에 조사를 수행한 경상북도 내 위치한 산림유전자원보호구역 3개 지역(봉화・영주・울진)의 곤충 군집 변화를 확인하기 위하여 5월에서 9월까지 함정 트랩(pitfall trap)을 이용하여 5회씩 3반복하여 각각 상대적으로 비교 하였다. 채집된 딱정벌레류는 딱정벌레과 등 22과 141종 2,415개체가 확인 되었으며, MRPP (Multi-response Permutation procedures)분석 결과 서식지간의 군집구조차이가 있음을 확인 하였고(p < 0.001), Bray-cutis 분석결과 군집간의 차이와 함께 신갈나무 군락이 보행성 딱정벌레류의 종 풍부도에 큰 영향을 주는 것으로 나타났고 소나무군락 은 비교적 낮은 영향을 받았다. 식생유형에 대한 지표종 분석결과 신갈나무 군락에서 붉은칠납작먼지벌레(Synuchus cycloderus Bates, 1873)를 포함한 4종, 자작나무 군락에서는 노랑털검정반날개(Ocypus weisei Harold, 1877)를 포함한 3종, 소나무 군락에서는 홍딱지반날개(Platydracus brevicornis Motschulsky, 1862)를 포함한 3종의 지표종 변화를 확인 하였다.

Tumor necrosis factor-α and interleukin-1β increases CTRP1 expression in adipose tissue

Kim, Kun-yong,Kim, Hwa Young,Kim, Jae Hyeong,Lee, Chul-Ho,Kim, Do-Hyung,Lee, Young Ho,Han, Seung Hyun,Lim, Jong-Seok,Cho, Dae Ho,Lee, Myeong-Sok,Yoon, Sukjoon,Kim, Keun Il,Yoon, Do-Young,Yang, Young Elsevier 2006 FEBS letters Vol.580 No.16

<P><B>Abstract</B></P><P>CTRP1, a member of the CTRP superfamily, consists of an N-terminal signal peptide sequence followed by a variable region, a collagen repeat domain, and a C-terminal globular domain. CTRP1 is expressed at high levels in adipose tissues of LPS-stimulated Sprague-Dawley rats. The LPS-induced increase in CTRP1 gene expression was found to be mediated by TNF-α and IL-1β. Also, a high level of expression of CTRP1 mRNA was observed in adipose tissues of Zucker diabetic fatty (<I>fa/fa</I>) rats, compared to Sprague-Dawley rats in the absence of LPS stimulation. These findings indicate that CTRP1 expression may be associated with a low-grade chronic inflammation status in adipose tissues.</P>

Adiponectin is a negative regulator of NK cell cytotoxicity.

Kim, Kun-Yong,Kim, Jae Kwang,Han, Seung Hyun,Lim, Jong-Seok,Kim, Keun Il,Cho, Dae Ho,Lee, Myeong-Sok,Lee, Jeong-Hyung,Yoon, Do-Young,Yoon, Suk Ran,Chung, Jin Woong,Choi, Inpyo,Kim, Eunjoon,Yang, Young American Association of Immunologists 2006 Journal of Immunology Vol.176 No.10

<P>NK cells are a key component of innate immune systems, and their activity is regulated by cytokines and hormones. Adiponectin, which is secreted from white adipose tissues, plays important roles in various diseases, including hypertension, cardiovascular diseases, inflammatory disorders, and cancer. In this study the effect of adiponectin on NK cell activity was investigated. Adiponectin was found to suppress the IL-2-enhanced cytotoxic activity of NK cells without affecting basal NK cell cytotoxicity and to inhibit IL-2-induced NF-kappaB activation via activation of the AMP-activated protein kinase, indicating that it suppresses IL-2-enhanced NK cell cytotoxicity through the AMP-activated protein kinase-mediated inhibition of NF-kappaB activation. IFN-gamma enhances NK cell cytotoxicity by causing an increase in the levels of expression of TRAIL and Fas ligand. The production of IFN-gamma, one of the NF-kappaB target genes in NK cells, was also found to be suppressed by adiponectin, accompanied by the subsequent down-regulation of IFN-gamma-inducible TRAIL and Fas ligand expression. These results clearly demonstrate that adiponectin is a potent negative regulator of IL-2-induced NK cell activation and thus may act as an in vivo regulator of anti-inflammatory functions.</P>

걷기가 비만 청소년의 AOPP 및 염증인자에 미치는 영향

소용석(Yong-Seok So),김명일(Myeong-il Kim) 한국엔터테인먼트산업학회 2014 한국엔터테인먼트산업학회 학술대회 논문집 Vol.2014 No.5

본 연구는 비만 청소년을 대상으로 걷기 운동을 실시하여 AOPP와 염증유발 인자에 미치는 영향을 규명하는데 목적이 있다. 연구 대상자는 B광역시 B고등학교에 재학 중인 17-19세의 비만 남자 고등학생 20명을 대상으로 운동군 10명과 대조군 10명을 대상자로 선정하였다. 12주간 주3-5회 걷기를 실시하였고, 1-5주까지는 40-60% HRR, 6-12주까지는 61-70% HRR 으로 주기별로 점증시켰다. 측정항목은 신체조성과 혈압을 측정하였고, 혈액은 혈중지질과 advanced oxidation protein products(AOPP), interleukin-6(IL-6), monocyte chemoattractant protein-1(MCP-1), high sensitivity C-Reactive Protein(hs-CRP)을 분석하였다. 통계처리는 SPSS 19.0을 이용하여 반복측정 이원분산분석을 이용하였으며, 사후분석으로 t-검정을 실시하였다. 모든 유의수준(α)은 .05로 설정하였다. 본 연구결과 점증적 걷기가 비만 남자 고등학생의 체지방률과 체질량지수에서 상호작용이 나타났으며, 운동군이 대조군보다 체지방률과 체질량지수가 감소하는 경향을 나타냈다. AOPP의 변화에서도 운동군이 대조군보다 감소하는 경향을 나타냈다. 또한 염증유발 인자의 변화에서도 운동군이 대조군보다 IL-6, hs-CRP, MCP-1에서 감소하는 경향을 나타냈다. 이상과 같이 점증적 걷기는 비만 남자 고등학생의 체중, 체지방률, 체질량지수 감소 효과가 나타남으로서 비만 개선에 긍정적인 영향을 미쳤다. 또한 점증적인 걷기를 통해 비만으로 인한 신체적 스트레스의 감소가 산화 스트레스 감소와 염증유발 인자의 감소에 영향을 미쳐 건강증진과 비만 예방 및 개선에 효과적인 것으로 나타났다. 따라서 비만인에 있어서 혈중 AOPP 농도는 혈중지질성분과 염증유발 인자들의 개선으로 미루어 보았을 때 심혈관계질환을 예측할 수 있는 인자로 사용될 수 있을 것으로 사료된다. 향후 심혈관계 질환을 가지고 있는 환자들을 대상으로 다양한 운동 프로그램을 통해 산화 단백질 손상지표에 관한 추가 연구가 필요할 것으로 생각된다.

A hot-water extract of <i>Sanguisorba officinalis</i> ameliorates endotoxin-induced septic shock by inhibiting inflammasome activation : HSO attenuates inflammasome activation

Seo, Dong-Won,Cho, Yong-Il,Gu, Suna,Kim, Da-Hee,Yi, Young-Joo,Lee, Sang-Myeong Center for Academic Publications Japan 2018 Microbiology and immunology Vol.62 No.1

<P>The inflammasome is a multiprotein signaling complex that mediates inflammatory innate immune responses through caspase 1 activation and subsequent IL-1 secretion. However, because its aberrant activation often leads to inflammatory diseases, targeting the inflammasome holds promise for the treatment of inflammation-related diseases. In this study, it was found that a hot-water extract of Sanguisorba officinalis (HSO) suppresses inflammasome activation triggered by adenosine 5-triphosphate, nigericin, microbial pathogens, and double stranded DNA in bone marrow-derived macrophages. HSO was found to significantly suppress IL-1 production in a dose-dependent manner; this effect correlated well with small amounts of caspase 1 and little ASC pyroptosome formation in HSO-treated cells. The anti-inflammatory activity of HSO was further confirmed in a mouse model of endotoxin-induced septic shock. Oral administration of HSO reduced IL-1 titers in the serum and peritoneal cavity, increasing the survival rate. Taken together, our results suggest that HSO is an inhibits inflammasome activation through nucleotide-binding domain and leucine-rich repeat pyrin domain 3, nucleotide-binding domain and leucine-rich repeat caspase recruitment domain 4 and absent in melanoma 2 pathways, and may be useful for treatment of inflammasome-mediated diseases.</P>

Comparison of immune cell populations in bronchoalveolar lavage cells and PBMC cytokine expressions in porcine reproductive and respiratory syndrome and porcine respiratory disease complex

Myeon-Sik Yang,정창기,Salik Nazki,Sameer ul Salam Mattoo,Sang-Myeong Lee,Won-Il Kim,Bumseok Kim 한국동물위생학회 2019 韓國家畜衛生學會誌 Vol.42 No.4

Porcine reproductive and respiratory syndrome (PRRS) is characterized by reproductive failure in sows and respiratory distress in all age pigs. Porcine respiratory disease complex (PRDC) is a disease caused by opportunistic bacterial infection secondary to a weakened immune system by a preceding respiratory infection. In this study, we tried to compare the immune responses in PRRS and PRDC groups to clearly characterize the disease severity. Eighty-five pigs were infected with various Korean field PRRS virus strains. Infected animals were classified into PRRS (n=32) and PRDC (n=53) groups based on lung le-sions such as interstitial pneumonia, suppurative pneumonia, and pleuropneumonia. The immune cell population of bronchoalveolar lavage cells (BALc) was evaluated on 14 and 28 days post infection (dpi) and PMBC cytokine expression was measured on 0, 3, 7, 14 dpi to investigate early inflammatory re-actions. Pulmonary lesion severity was negatively correlated with alveolar macrophage (AM) in both PRRS and PRDC groups on 14 and 28 dpi. AM in BALc was less populated in PRDC group on 28 dpi compared to PRRS group. AM in BALc was significantly less populated in PRDC group on 28 dpi compared to 14 dpi. In addition, cytotoxic T lymphocyte (CTL) in BALc was higher populated in PRDC group on 14 dpi and 28 dpi compared to PRRS group. In the case of PBMC cytokine TNF-, IFN-, IL-1, IFN-, FoxP3, and IL-2, the PRRS group showed higher expression than the PRDC group on 7 dpi, 14 dpi, 7 dpi, 14 dpi, 14 dpi, and 14 dpi, respectively. On the other hand, in the case of IFN-, IL-6, IL-8, IL-4, and IL-17, the PRDC group showed higher PBMC cytokine expression at 14 dpi, 7 dpi, 14 dpi, 3 dpi, and 3 dpi, respectively, than the PRRS group. Based on these results, our study could characterize differential immune responses in pigs with PRRS or PRDC.

Comparison of immune cell populations in bronchoalveolar lavage cells and PBMC cytokine expressions in porcine reproductive and respiratory syndrome and porcine respiratory disease complex

Yang, Myeon-Sik,Jeong, Chang-Gi,Nazki, Salik,Mattoo, Sameer ul Salam,Lee, Sang-Myeong,Kim, Won-Il,Kim, Bumseok The Korean Society of Veterinary Service 2019 韓國家畜衛生學會誌 Vol.42 No.4

Porcine reproductive and respiratory syndrome (PRRS) is characterized by reproductive failure in sows and respiratory distress in all age pigs. Porcine respiratory disease complex (PRDC) is a disease caused by opportunistic bacterial infection secondary to a weakened immune system by a preceding respiratory infection. In this study, we tried to compare the immune responses in PRRS and PRDC groups to clearly characterize the disease severity. Eighty-five pigs were infected with various Korean field PRRS virus strains. Infected animals were classified into PRRS (n=32) and PRDC (n=53) groups based on lung lesions such as interstitial pneumonia, suppurative pneumonia, and pleuropneumonia. The immune cell population of bronchoalveolar lavage cells (BALc) was evaluated on 14 and 28 days post infection (dpi) and PMBC cytokine expression was measured on 0, 3, 7, 14 dpi to investigate early inflammatory reactions. Pulmonary lesion severity was negatively correlated with alveolar macrophage (AM) in both PRRS and PRDC groups on 14 and 28 dpi. AM in BALc was less populated in PRDC group on 28 dpi compared to PRRS group. AM in BALc was significantly less populated in PRDC group on 28 dpi compared to 14 dpi. In addition, cytotoxic T lymphocyte (CTL) in BALc was higher populated in PRDC group on 14 dpi and 28 dpi compared to PRRS group. In the case of PBMC cytokine TNF-α, IFN-α, IL-1β, IFN-γ, FoxP3, and IL-2, the PRRS group showed higher expression than the PRDC group on 7 dpi, 14 dpi, 7 dpi, 14 dpi, 14 dpi, and 14 dpi, respectively. On the other hand, in the case of IFN-β, IL-6, IL-8, IL-4, and IL-17, the PRDC group showed higher PBMC cytokine expression at 14 dpi, 7 dpi, 14 dpi, 3 dpi, and 3 dpi, respectively, than the PRRS group. Based on these results, our study could characterize differential immune responses in pigs with PRRS or PRDC.

긴 관동맥병변에서 긴 스텐트삽입에 대한 임상경과 및 재협착율

김영학,박성욱,정상식,박훈기,이상곤,이일수,이철환,김재중,홍명기,박승정 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.6

사회복지관의 브랜드 아이덴티티 구축에 관한 연구

김일명 東國大學校 行政大學院 2005 행정논집 Vol.32 No.-

21세기 새로운 사회변화의 한 지표로서, 사회복지와 같은 비영리부분에서 민간 조직들의 활동이 늘어나고 있다. 특히 종교기관과 시민단체를 중심으로 사회복지 분야의 자발적인 참여가 활성화되면서 기관의 차별화는 더욱 가속화되고 있으며, 이는 전체 사회복지의 방향설정에 큰 영향을 미치고 있다. 영리와 비영리 조직을 막론하고 전체 조직의 관리와 경영에서 이미지 구축이 매우 강조되면서 브랜드 경영이 새로운 패러다임으로 급부상하고 있다. 사회복지관과 같은 비영리조직의 관리와 경영도 새로운 방향설정에 따른 혁신이 필요한 시점에서 브랜드적 사고의 도입은 매우 유용하다고 볼 수 있다. 따라서 본 연구의 목적은 사회복지와 브랜드적 사고(brand mind)가 어떻게 결합되는지에 대해 살펴보고, 사회복지 브랜드 전략의 기초인 브랜드 아이덴티티(brand identity)의 구성요소와 관점, 사회복지관 슬로건 및 비전 분석을 통해 사회복지관 브랜드 아이덴티티 구축에 관한 시사점을 제공하고자 한다. 종교기관 및 시민단체에서 위탁운영중인 188곳의 종합사회복지관의 슬로건과 비전을 분석한 결과 BI(Brand Identity)라는 용어를 사용한 곳은 1군데 있었으며, 슬로건과 비전이 있는 곳은 26 곳 이었다. 또한 BI를 채택한 1곳의 종합사회복지관을 제외하고는, 슬로건이나 비전 설정이 거의 비슷해서 차별성이 없었다. As a baromaeter of new social changes in 21st century, it is worth noting the increasing participations of pricate organizations in noncommercial, non government sectors such as social welfare. Especially, as voluntary participations mainly led by religious organizations and civic groups in social welfare sectors have become substantially active, the differentiation among organizations is getting accelerated. This in turn seems to have a significant effect on setting directions of social welfare as a whole. Whether in commercial or in noncommercial organizations, brand management is emerging as a new paradigm on account of the fact that creating and establishing an image is being greatly emphasized in the management and administration of the organizations. It seems to be of great use to introduce and promote Brand Mind at this juncture in need of an innovation while developing and facilitating new direction for the management and administration of noncommercial organizations such as social welfare facilities. Therefore, the purpose of this study is to examine as to how social welfare and Brand Mind are incorporated and to provide implications of establishing Brand Identity in social welfare facilities through analyzing structural elements and perspectives of Brand Identity as well as slogans and visions of social welfare facilities as a basis of social welfare brand strategy. When slogans and visions of 188 social welfare facility complexes, where religious organizations and civic groups are in charge of the facility management, were investigated, the results showed that there was I place that used the term 'Brand Identity (BI), 26 had slogans and visions. Also, except for one social welfare facility that utilized BI, there was no distinctind among the facilities as they had similar slogans and visions. Thus, it is clear thet we are in a desperate need of introducing and utilizing brand concept since noncommercial organizations like social welfare facilities seem to have no compectitive edge or try to actively get distinguished from others in this competitive time. Establishing Brand Identity of social welfare facilities creates and produces a positive image of the organizations, which in turn allows them to have a strong brand culture both internally and externally. As a result, it becomes a basis of brand strategy for securing clients, recruiting sponsors, and getting support from the local community.

한국 프로야구 선수의 체력 평가기준치 설정

김명일 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

This paper concerns the standard assessment criteria for the physical strength of the professional baseball players. The physical strength test on the professional baseball players has been implemented and analyzed. The result of the analysis is as follows: 1. With regards to the body fore-bending, the average of the professional baseball players was 16.3m, which is higher than that(10.5m) of males in their twenties. With regards to sit-ups, the average number of sit-ups was 52.6 times whereas that of males in their twenties was 33.3 times. 2. With regards to side step, the average of the professional baseball players was 39.9 times, which is a little higher than that(36.4 times) of males in their twenties. With regards to standing jump, the average of the professional baseball players was 61.6m, which is higher than that(49.6m) of males on their twenties. 3. With regards to grasping power, the average of the professional baseball players was 56.7㎏, which is a little higher than that(50.5㎏) of males in their twenties. With regards to push-ups, the average of the professional baseball players was 46.4 times, which is higher than that(36.4 times) of males on their twenties. 4. The standard assessment criteria will be utilized usefully by trainers, rehabilitation experts, baseball coaches, or other baseball athletes in their high schools or universities who want to be professional players.