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흰쥐에서 음경발기 평가의 척도로서 음경해면체내압측정술 확립
송윤섭,김용준,이광우,김준모,문기혁,박영호,민영기,유형균,김형건 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1
Purpose: Because studies about the control of penile erection at the entral nervous system was dependent on the animal experiments, establishment of measuring penile erection is important to evaluate the effects changes at the central nervous system on the penile erection. Intracavernous pressure measurement in rats has been introduced as a suitable index for the evaluation of penile erection but this method is invasive and technically difficult. So, we established the intracavernous pressure measurement in rats as the experimental index for penile erection. Materials and Methods: 42 male adult Sprague-Dawley rats (250-300gm) were divided to saline or papaverine treated group. Rats were placed on a heating table to maintain their body temparature and anesthetized with 50mg/kg of pentobarbital sodium by intraperitoneal injection. A cannula was inserted to the left carotid artery to measure systemic blood pressure. Saline (0.05, 0.1ml), papaverine(0.05, 0.1, 0.25, 0.5, 1.0, 2.0mg) were injected intracavernously via 26 guage needle filled with saline or papaverine which connected to pressure transducer and polygraph was inserted into the corpus cavernosum on one side to inject the drug and to measure intracavernous presure. Results: Properly executed insertion and intracavernous administration produced a instantaneous but transient rise in intracavernous pressure that substantially stabilized and maintained at 5.4±0.4mmHg. Intracavernous pressure and duration of penile blood flow following intracavernous injection of papaverine are increased comared to those of saline. Conclusions: Monitoring intracavernous pressure in rats represents a suitable index for the evaluation of penile erection in small laboratory animals.
마이크로 컴퓨터를 이용한 다종의 전동기 속도제어 장치의 설계
李俊煥,宋祥燮,咸雲哲 全北大學校 1983 論文集 Vol.25 No.-
In this paper, we show that synchronous and dc motor speed controllers are designed with PLL based frequency synthesizer method. In addition, microcomputer based stepper motor speed controller is also designed. All these controllers are connected to SRC-80 microcomputer to input the speed command through hex-key button.
적응제어를 이용한 Tacho 발전기의 전압 regulation 에 관한 연구
함운철,송상섭,이준환 全北大學校 1984 論文集 Vol.26 No.-
In this paper, Indirect adaptive control based on gradient algorithm is applied to the voltage regulation of tachometer connected to the D.C motor. Experimental over all system is assumed to be a second order linear discrete system. Experiment Data are abtained using HP-1000 minicomputer and 2240 A measurement and control processor. In section Ⅰ, and Ⅱ, the history of adaptive control theory and the indirect adaptive control theory using state variable filter are introduced. The experimental result and conculusion are discussed in section Ⅲ, and Ⅳ.
서성규,이정섭,송준석 國立麗水大學校 環境問題硏究所 2004 環境硏究論文集 Vol.6 No.-
This study was investigated the effects of various system parameters on the absorption of carbon dioxide into absorption solution. An aqueous potassium carbonate solution was used as a chemical absorbent in order to figure out the effect of chemical reaction. For this purpose, the chemical analysis of potassium carbonate solution was performed. The changes of pressure, temperature, K₂CO₃solution flow/feed gas ratio and solution concentration in the absorber and the changes of pressure and temperature in the stripper were also analyzed. The analysis result shows that K₂CO₃ concentration in potassium carbonate solution was 99.6%. The optimum pressure was found to be 27.0㎏/㎠ and the optimum temperature was to be 68℃, the optimum concentration of potassium carbonate solution was to be 26.0wt% in the absorber. The CO₂ leakage decreased with the increment of the K₂CO₃ solution flow/feed gas ratio. But the H₂ leakage in the CO₂ product increased at or above the K₂CO₃ solution flow/feed gas ratio of 1.10. This H₂ leakage induced by the loss of ammonia production. The effects of the changes of the operation condition of the CO₂ stripper to the K₂CO₃ conversion are as follows. The K₂CO₃ conversion decreased as the pressure decreased. The K₂CO₃ conversion increased as the temperature increased. However, increasing the temperature without decreasing the pressure did not bring positive effect. The optimum pressure was found to be 0.45㎏/㎠.
표준 내시경유두괄약근절개술에서 사용 전류에 따른 합병증 발생의 비교
이세준 ( Lee Se Jun ),송기섭 ( Song Gi Seob ),정준표 ( Jeong Jun Pyo ),이덕용 ( Lee Deog Yong ),정연수 ( Jeong Yeon Su ),지상원 ( Ji Sang Won ),백용한 ( Baeg Yong Han ),박승우 ( Park Seung U ),송시영 ( Song Si Yeong ),이관식 ( Lee 대한소화기학회 2004 대한소화기학회지 Vol.43 No.3
Background/Aims: The blended current is usually used for endoscopic sphincterotomy (EST) to minimize bleeding. The pure cutting current may induce less edema of the ampulla and therefore result in less injury to the pancreas theoretically. The aim of this study was to evaluate effects of electric currents used on the development of serum pancreatic enzyme evaluation, clinical pancreatitis or bleeding after EST. Methods: One hundred and eighteen consecutive patients who underwent EST with standard papillotome alone for the treatment of choledocholithiasis were reviewed. All EST had been performed by two endoscopists whose experience on EST was similar: one uses blended current(BC group, n=74), while the other uses pure cutting current (PC group, n=44). Results: Baseline clinical, laboratory, and procedural parameters were similar in both groups. The incidences of hyperamylasemia and hyperlipasemia were similar between two groups. There was no significant difference in the incidence of clinical pancreatitis between two groups (BC 6.8% vs PC 0.0%, p=0.1557). All episodes of pancreatitis were mild. No episodes of significant bleeding occurred after EST. The incidences of sepsis, cholangitis and perforation were also not different between two groups. Conclusions: Development of complications after standard EST such as hyperamylasemia, clinical pancreatitis, and bleeding may not depend on the electric current used. (Korean J Gastroenterol 2004;43:204-210)
수아종에서 DNS Ploidy, P53, PCNA의 예후인자로서의 의의성에 관한 연구
송준혁,박윤관,정용구,정흥섭,서중근,이기찬,이훈갑 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.11
Medulloblastoma is a common intracranial neoplasm of childhood. Multiple clinical and therapeutic factors have been described to predict the outcome of patients with medulloblastoma. There were several studies about the usefulness of the DNA ploidy, the presence of mutation of p53 gene, and PCNA as predictors of the prognosis in the various type of intracranial tumors. The current study investigates the relationship between DNA ploidy, PCNA, mutation of p53 and the clinical course of the medulloblastoma patients. We analyzed the extent of resection, p53 mutation, PCNA, age, sex, and tumor stage as the prognostic indicator in 13 children with medulloblastoma. The patients' age and sex were not related to survival(p>0.1). The extent of resection was related to the patients' survival(p=0.03). The DNA ploidy was marginally related to the patients outcome(p=0.1) and this probably is due to the small number of our patients. There were no correlations between tumor stage, PCNA, p53 and patients' survival. The current study suggests that the prognosis is mainly influenced by the extent of the tumor resection in medulloblastoma patients. The DNA ploidy is weakly corellated with the outcome of the patients. Neither the mutation of p53 gene nor the PCNA were correlate with patients' survival.
Nimodipine이 뇌척수액생성에 미치는 효과에 관한 실험적 연구
송준혁,박윤관,정흥섭,서중근,이훈갑,이기찬,주정화 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.9
The author has performed an experimental study in order to investigate the effect of nimodipine on the production of CSF in 12 cats. The cats were divided into 2 groups, one for nimodipine intravenous infusion and the other for its vehicle infusion group. Using ventriculo-cisternal perfusion method nimodipine and its vehicle were examined for their effects on CSF formation rate respectively. Baseline CSF formation rate was 22.5±2.9㎕/min(S.E.) and it gradually reduced to 17.0±3.4㎕/min(S.E.) after final infusion of nimodipine at 60㎍/㎏/min. Vehicle infusion revealed no significant change in CSF formation rate. Although the nimodipine insuion revealed declining tendency in CSF formation rate along with increment on nimodipine concentration, it was not statistically different from that of vehicle infusion group. Systolic blood pressure was significantly reduced after nimodipine infusion(133±31.8mmHg at baseline, 93.9±19.1mmHg at the end of the experiment) on oneway ANOVA test and it was significantly different from that in vehicle infusion group(p=<0.01).
宋相燮,咸雲哲,李俊煥 전북대학교 공업기술연구소 1983 工學硏究 Vol.13 No.-
A modified reference value is used at statring-up to reduce the transient overshoot of switching regulator. It normally depends upon the parameters such as applied input, desired output, and maximum allowable overshoot. By analyzing the data obtained from simulation results, it can be represented by a simple formula in terms of those parameter.