췌장 선방세포암 1예

이화정,지준호,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Acinar cell carcinoma is a rare tumor that represents 1~2% of al1 pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-o1d man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased ^(18)F-fluorodeoxyglucose (FDG) uptake Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the Pancreas The patient underwent a total gastrectomy three months later because of gastric recurrence Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabme.

원발성 후복막 점액낭샘암종 1예

지준호,이화정,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its Pathogenesis, optimal treatment, and prognosis. A 29-year-o1d pregnant woman (21 weeks) Presented with abdominal discomfort CA 19-9, CA 125, and CEA were normal Abdominal CT scanning revealed a 19x15x13 cm retropentoneal tumor Exploratory laparotomy and tumor excision were performed. Mucinous retropentoneal implants were removed as completely as possible Histologically, the tumor showed focal areas of capsular invasion, but free resection margins The uterus and both ovaries were normal in appearance No adjuvant therapy was pursued. Six months later, Peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous Cystadeno-carcinoma and present a review of the literature.

타원곡선을 이용한 암호시스템과 응용

이준락 三陟大學校 2005 論文集 Vol.38 No.-

타원곡선들에 기반을 둔 공개키 암호시스템이 지난 여러해 동안 연구되어왔다. 본 논문에서는, 타원곡선 암호시스템이 현존하는 공개키 방식과 같은 정도의 안정도를 가지면서 키 길이를 더 짧게 할 수 있을 가능성이 있음을 보여준다. 실질적으로 표수 2인체위에서의 타원곡선에 특별한 관심이 있다. 타원곡선을 이용한 ElGamal 암호시스템과전자지불 프로토콜이 설계된다. 마지막으로, H.Kuwakado, H. Tanaka의 알고리즘을Schnorr의 서명방식에 응용함으로써 그 전자서명을 확장하였다. Public key cryptosystems based on Elliptic curves have been studied for many years. In this thesis, we show that elliptic curve cryptosystems have the potential to provide security equivalent to that of the existing public key schemes, but with shorter key lengths. Of special interest, for practical reasons, are the curves over fields of characteristic 2. ElGamal cryptosystem and electronic payment protocol using the elliptic curve are also constructed. Finally, by applying algorithm proposed by H.Kuwakado and H. Tanaka to Schnorr 'signature scheme, we extend the digital signature.

궤적1인 타원곡선 이산대수 문제

이준락 三陟大學校 産業科學技術硏究所 2004 産業科學技術硏究論文集 Vol.9 No.1

In this paper we describe an elementary theory which leads to a linear algorithm for solving the elliptic curve discrete logarithm problem with trace one. In practice the method described means that when choosing elliptic curves to use in cryptography one has to eliminate all curves whose group orders are equal to the order of the finite order.

레반다이어트 식품섭취가 비만여성의 신체구성성분, 혈중 렙틴 및 지질수준에 미치는 영향

이규성,유병렬,정락희,김문희,송봉준,이길자 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.2

This study was to varify the effects of levan diet administration on body composition, blood leptin level and lipids components (TC, TG, LDL-C, HDL-C) in obese women during 8 weeks. The subjects of study were divided into 20-29year group (n=15) and 30-39year group (n=15) randomly selected. Administration of Levan Diet in this study was 2 times (breakfast, lunch or dinner) per day, 11tablets per 1times. Statistical method for data processing produced mean and SD of total variable. To analyze difference between groups and periods had executed 2? ANOVA. This study was given conclusion as follows: First, systolic blood pressure showed decrease after administration of levan diet in 30-39years, but it was not statistically significant. Second, body weight and %fat gradually decreased according to the application period of levan diet administration in 20-29years and 30-39years, and it was statistically significant (p<.05). Third, blood leptin level and blood lipid levels (TC, TG, LDL-C) showed decrease after administration of levan diet in 20-29years and 30-39years, but it was not statistically significant. In conclusion, this study shows that the administration of levan diet play a positive role as assistant diet. Therfore, levan diet administration should be recommended as ergogenic aids for these who do obese adults.

유한 Dirichlet 적분을 갖는 해석함수들의 Hilbert 공간

이준락 三陟大學校 産業科學技術硏究院 2005 産業科學技術硏究論文集 Vol.10 No.-

In this paper we study the Hilbert space of analytic functions with finite Dirichlet integral in a connected open set Q in the complex plane. We show that every such function can be represented as a quotient of two bounded analytic functions, each of which has a finite Dirichlet integral, This has several consequences for the structure of invariant subspaces of the algebra of multiplication operators in the Dirichlet space, in case Q is simply connected. Namely, we show that every nontrivial invariant subspace contains a nontrivial bounded function, that each two nontrivial invariant subspaces have a nontrivial intersection (that is, the algebra is "cellular indecomposable"), and that each nontrivial invariant subspace has the "codimension one" property with respect to certain multiplication operators.

BRIOT-BOUQUET 미분방정식에 대하여

이준락 三陟大學校 産業科學技術硏究所 2003 産業科學技術硏究論文集 Vol.8 No.1

Let β and γ be complex numbers, n a positive integer, let h be analytic in the unit disk U. This article describes conditions under which the Briot-Bouquet differential equation ◀(원본참조)▶ has analytic and univalent solutions. If h is also univalent then conditions are determined for the best dominants of the Briot-Bouquet differential subordination ◀(원본참조)▶ In addition, other differential subordinations are considered, together with applications to integral operators and to univalent functions.

A New Record of Cymatium encausticum (Ranellidae: Tonnoidea: Gastropoda) from Korea

Lee, Jun-Hee,Lee, Sang-Hwa,Lee, Jong-Rak,Park, Joong-Ki The Korean Society of Systematic Zoology 2012 Animal Systematics, Evolution and Diversity Vol.28 No.3

The Cymatium Roding, 1798 is a small- to large-sized marine gastropod genus. Three species has been reported thus far for Cymatium in the Korean waters. In general, Cymatium encausticum (Reeve, 1844) is known to occur in tropical seawaters including the Philippine Islands along with its congeners C. gutturnium, C. springsteeni, and C. exile. A single individual of the species was collected from Jejudo Island by SCUBA diving and morphological features were observed using a stereomicroscope. This is the first study to report the occurrence of Cymatium encausticum (Reeve, 1844) from the Korean waters, providing a detailed description of the species with the illustration for the shell morphology.

SIRT1 is required for oncogenic transformation of neural stem cells and for the survival of “cancer cells with neural stemness” in a p53-dependent manner

Lee, Ji-Seon,Park, Jeong-Rak,Kwon, Ok-Seon,Lee, Tae-Hee,Nakano, Ichiro,Miyoshi, Hiroyuki,Chun, Kwang-Hoon,Park, Myung-Jin,Lee, Hong Jun,Kim, Seung U.,Cha, Hyuk-Jin Oxford University Press 2015 Neuro-oncology Vol.17 No.1

<P><B>Background</B></P><P>Cancer stemness, observed in several types of glioma stem cells (GSCs), has been demonstrated to be an important barrier for efficient cancer therapy. We have previously reported that cancerous neural stem cells (F3.Ras.CNSCs), derived from immortalized human neural stem cells by a single oncogenic stimulation, form glial tumors in vivo.</P><P><B>Method</B></P><P>We searched for a commonly expressed stress modulator in both F3.Ras.CNSCs and GSCs and identified silent mating type information regulation 2, homolog (SIRT1) as a key factor in maintaining cancer stemness.</P><P><B>Result</B></P><P>We demonstrate that the expression of SIRT1, expressed in “cancer cells with neural stemness,” is critical not only for the maintenance of stem cells, but also for oncogenic transformation. Interestingly, SIRT1 is essential for the survival and tumorigenicity of F3.Ras.CNSCs and GSCs but not for the U87 glioma cell line.</P><P><B>Conclusion</B></P><P>These results indicate that expression of SIRT1 in cancer cells with neural stemness plays an important role in suppressing p53-dependent tumor surveillance, the abrogation of which may be responsible not only for inducing oncogenic transformation but also for retaining the neural cancer stemness of the cells, suggesting that SIRT1 may be a putative therapeutic target in GSCs.</P>

GENERALIZED BOUNDED ANALYTIC FUNCTIONS IN THE SPACE H_ω_,p

Lee, Jun-Rak The Kangwon-Kyungki Mathematical Society 2005 한국수학논문집 Vol.13 No.2

We define a general space $H_{{\omega},p}$ of the Hardy space and improve that Aleman's results to the space $H_{{\omega},p}$. It follows that the multiplication operator on this space is cellular indecomposable and that each invariant subspace contains nontrivial bounded functions.