Selenium 부족 식이가 흰쥐 간장에 미치는 영향

김은희,이현기,양영철,차인준 인제대학교 1990 仁濟醫學 Vol.11 No.3

Se 부족에 의하여 랫트의 체중과 사료 섭취량은 감소되었으며 혈중 LDH, GOT와 간장조직의 glutathion 농도는 정상보다 증가되었다. Se 부족군의 조직학적 소견은 간세포의 공포화 변성, 간조직의 PAS 반응 저하, LDH 활성화 감소 및 ACP 활성의 증가를 나타내었으며, rER의 분절화 현상 및 감소와 mitochondria의 종창 등이 관찰되었다. The objective of this study was to determine the effect of Se-deficient diet on the weight gain, chemical changes in plasma and microstructural change of liver in rat. Rats were divided into 2 diet groups (Se-deficient diet) and control diet and sacrificed after 21days of feeding. Levees of LDB, GOT, GPT of Plasma arid glutathione of liver were determined and light microscopic and electron microscopic observation of ret liver were performed. Total weight gaits (P<0.05) and feed efficiency radio (P<0.001) were significantly lower in Se-deficient group than in control group, whereas the levels of plasma LDH (P<0.001) and GOT (P<0.05) were increased significantly in Se-deficient group. Furthermore, the levels of total glutathione (P<0.01) and reduced glutathione (P<0.001) showed significant increase in Se-deficient group. Light microscopic observations showed that cytoplasmic blooning degeneration and pyknosis of nuclei were often found around portal canal of Se-deficient group by H-E straining. PAS staining also showed weakly positive reaction around central area, whereas PAS negative reacting cells were often observed around portal canal of Se-deficient group. Histochemical staining skewed that cytochrome oxidase activity were very active in both groups, whereas LDH activity was significantly decreased arid ACPase activity was significantly increased in Se-deficient group. Electron microscopic observation showed that the number of rER were decreased and the blooning degeneration of rEr was often observed in Se-deficient group. Mitochondria with mayeline figure arid wooly density were also observed in Se-deficient group. Light microscopic observations showed that cytoplasmic blooming degeneration and pyknosis of nuclei were often found around poral canal of Se-deficient group by H-E staning. PAS staining also showed weakly positive reaction around central area, whereas PAS negative reacting cells were often observed around portal canal of Se-deficient group. Histochemical staining showed that sytochrome oxidase activity were very active in both groups, whereas LDH activity was significantly decreased and ACPase acclivity was significantly increased in Se-deficient group. Electron microscopic observation stewed that the number of rER were decreased and the blooning degeneration of rER was often observed in Se-deficient group. Mitochondria with myeline figure and wooly density were also observed in Se-deficient group.

기혼여성의 스포츠와 여가만족도 규정요인에 관한 연구

김유수,안종학,최인순,안영필 東亞大學校附設스포츠科學硏究所 1998 스포츠科學硏究論文集 Vol.16 No.-

As society has been changing rapidly, so the evaluation of women's position and the value of leisure has been changing. Women's demanding of leisure activities is also increasing today. I studied on the factors which have effected on the satisfaction of leisure time's married women in cities with involvement of leisure and sports activities. The results are as follows ; 1. Married women's leisure and sports activities by ages & educational level. (a) As for married women in cities, the older they are the more they took experiences in sports activities for a year. I think it is desirable but in health care it is concerned that young married women in cities don't take part in sports activities. (b) The higher their ages are, the more time is required for exercise in a time. (c) The old age group at 60s expressed the most active attitudes in joining sports clubs. (d) The young age group of 20s preferred to join clubs in their work and public centers while the old age group of 60s, 88.9%, definitely prefered to join clubs in public centers. (e) In the joining sports clubs, married women in 30s will was highest, while the old age group of 60s and over was lowest. (f) In the last one year, housewife participating in 20s was comparatively lower. (g) In the satisfaction of leisure time, the old age group of 60s and over was highest while the young age group of 20s was lowest. That is, the more ages were highter the more the satisfaction of leisure time was. (h) In the percentage of participating in sports activities in the last one year, the married women who finished only middle school was highest, 95.7%, So the higher educational level is the lower the percentages of that is, (i) In the time required, the higher educational level is, the shorter the time became. (j) In the facilities, many married women who finished university used them in their works or schools, or public centers. (k) In the time of moving to the facilities, there was little difference in educational levels, but the time of married women who finished university was less than others. (l) In the participating in several lectures, the higher educational level was, the higher the percentage was. (m) In the satisfaction of leisure time, the higher educational level was, the lower the percentage was, So I don't think the programs and condition of leisure and sports activities satisfy married women of high educational level. 2. The list of factors which have effected on the satisfaction of leisure time, are as follows ; (a) the attitudes of leisure time or sports activities, (b) the result of leisure time or sports activities(treatment for hypochondria and anxiety) (c) the result of leisure time or sports activities(treatment for shoulder pain and backache, and relief of worries) (d) the time required in a time. (e) confidence of body activities (f) the result of leisure time and sports activities(they got confidence and satisfaction) (g) the frequency of participating in leisure and sports activities in the last one year. (h) the result of leisure time and sports activities(they became to be friendly with and became kind to others) (i) the result of leisure time and sports activities(they became to plan their life-styles actively) (j) health condition. From these lists I could understand the most important factor is the body activity-oriented leisure time activities of married women in cities.

탄광부 진폐증의 운동지수

조영선,김세곤,문우기,유재인,정치경 가톨릭대학 산업의학 센타 산업의학연구소 1984 韓國의 産業醫學 Vol.23 No.3

Exercise index(EI) was measured on 933 pneumoconiosis patients (865 patients with small rounded opacities and 68 patients with large opacities) and 176 suspected pneumoconiosis patients from Korean anthracitic mines, in order to evaluate the ventilatory impairment of pulmonary function according to the chest radiographic findings of pneumoconiosis. Exercise index was obtained from the maximum breathing capacity (MBC) and the exercise ventilation volume(EV) which were measured by spirometer and two step-test. Classification of pneumoconiosis was based on the international classification of ILO U/C. The results were as follows: 1. The mean value of E1 was significantly increased in pneumoconiosis patients with large opacities(46.0%) than in patients with small rounded opacities(26.5%) and with suspected pneumoconiosis(25.0%). The number of jpatients in substandard EI was 97.1% in patients with large opacities but 49.4% in patients with small rounded opacities and 40.3% in patients with suspected pneumoconiosis. 2. The mean values of EI and the number of patients in substandard EI were markedly increased in pneumoconiosis patients with small rounded opacities and suspected over 50 years of age. However, the number of patients in substandard EI showed no association with age in pneumoconiosis patients with large opacitis. 3. In pneumoconiosis patients with small rounded opacities, the mean values of EI and the number of patients in substandard EI showed significant association with the profusion (category) but no significant association with the type of small rounded opacities. 4. In pneumoconiosis patients with large opacities, the mean values of EI and the number of patients in substandard EI showed no significant difference between patients complicated with and without pulmonary tuberculosis. 5. No significant association of EI and the number of patients in substandard EI with the size of large opacities was observed in pneumoconiosis patients with large opacities, however, the mean values of EI showed increasing tendenccy in category B and C compared to category A.

하지 절단자 보행의 운동역학적 분석

임규찬,박윤서,배성제,정철수,신인식,김복영 師範大學 體育硏究所 1994 서울大學校 體育硏究所論集 Vol.15 No.2

This study was conducted to investigate the biomechanical characteristics of the gait pattern in an amputee for the purpose of improving the proper gait posture and designing the prosthetic. The subjects were six males amputees and one normal person. The ground reaction force was measured using AMTI force platform. The conclusions were as follows; 1. In case of amputee group, the ground reaction force was revealed in specific figure according to position in which they used the prosthetic, whereas in case of normal person the ground reaction force was revealed in the figure of two humps in regard of vertical axis. 2. In case of amputee group, the ground reaction force in time between fight foot contact and left foot contact was deviated from a figure of rectangle, whereas in case of normal person the ground reaction force was revealed in the figure of rectangle. 3. In case of amputee group, the ground reaction force referred to both feet angle point of view was revealed in irregular figure, whereas in case of normal person the ground reaction force was revealed about 47。

淫羊藿의 「마우스」性週期에 미치는 影響

金永寅 의약계사 1957 의약계 Vol.2 No.1

거래비용과 교육훈련

서인석,김우영 한국직업능력개발원 2008 직업능력개발연구 Vol.11 No.2

본 연구의 목적은 Williamson(1975; 1985)의 거래비용이론에 입각하여 환경 불확실성과 인적자본 특수성이 우리나라 근로자의 교육훈련 참여율에 어떤 영향을 미치는지를 알아보는 것이다. Williamson의 거래비용이론에 따르면, 기업을 둘러싼 환경이 불확실할수록, 또한 기업이 사용하는 인적자본 특수성이 높을수록, 노동시장이 내부화 되고 따라서 근로자에 대한 교육훈련은 확대될 것으로 예상된다. 본 연구에서는 이러한 이론적 예측이 우리나라 기업에 잘 적용되는지를 검증하고자 한다. 본 연구의 결과는 거래비용이론에 따른 예측이 전반적으로 우리나라 기업현실에는 잘 적용되지 않는다는 것이다. 환경 불확실성이 높을수록 근로자의 교육훈련참여는 증가하는 것으로 나타났지만 인적자본 특수성 높을수록 오히려 교육훈련참여율이 낮으며, 환경 불확실성과 인적자본특수성이 함께 높아질 경우 교육훈련에 미치는 추가적인 영향은 없는 것으로 나타났다. 이러한 결과를 통하여 볼 때 우리나라 기업들은 거래비용을 줄이는 방향으로 교육훈련을 실시하지 못하고 있다고 사료된다. 특히 특수적 숙련을 가진 사람에 대한 교육훈련이 적게 이루어지는데 이는 장기적으로 우리나라 기업들의 경쟁력을 약화시키는 결과를 초래할 수 있기 때문에 앞으로 좀 더 세심한 인적자원관리가 요청된다. The purpose of this study is to examine the effects of environmental uncertainty and the specificity of human resources on training participation rates of Korean workers, in the light of the theory of transaction costs proposed by Williamson(1975, 1985). According to the theory of transaction costs, workers participate more in training as the environmental uncertainty surrounding firms increases and the specificity of human capital possessed by workers deepens. This study tests whether or not the predictions coming from the theory of transaction costs can conform with training participation behavior of Korean workers. The obtained results indicate that the theory of transaction costs does not explain well the training participation behavior of Korean workers in general. Environmental uncertainty tends to increase training participation of workers, but the specificity of human capital does not. Interaction between environmental uncertainty and the specificity of human capital also has no effect on the training participation rate. The results of this study indicates that Korean companies have not adopted an efficient system of human resources management in terms of reducing transaction costs.

無脈症 : 人造血管 移植手術 및 剖檢例 A Case of Aortico-carotid Prosthetic Vascular Graft and Autopsy

孔寅浩,鄭埈,崔秉茂,李寧均,柳命珪,李聖洙,金勇一 최신의학사 1962 最新醫學 Vol.5 No.4

Quantitative in‐line monitoring of solvent‐mediated polymorphic transformation of sulfamerazine by near‐infrared spectroscopy

Lee, Min‐,Jeong,Seo, Da‐,Young,Wang, In‐,Chun,Chun, Nan‐,Hee,Lee, Hea‐,Eun,Jeong, Myung‐,Yung,Kim, Woo‐,Sik,Choi, Guang J. Wiley Subscription Services, Inc., A Wiley Company 2012 journal of pharmaceutical sciences Vol.101 No.4

<P><B>Abstract</B></P><P>The in‐line monitoring of pharmaceutical processes with high risk, such as crystallization, has been one of the most popular research topics in recent years. Sulfamerazine (SMZ), a well‐known sulfonamide antibacterial agent was investigated to examine the mechanism of polymorphic conversion by solvent‐mediated polymorphic transformation (SMPT). The primary purpose of this study is to monitor the polymorphic transformation through in‐line near‐infrared (NIR) measurements and concurrently interpret the whole process quantitatively with off‐line characterizations. Samples taken at every hour during SMPT were analyzed by X‐ray diffractometry (XRD) and differential scanning calorimetry (DSC). NIR spectra in the range of 7500–4900 cm<SUP>−1</SUP> were taken into account for multivariate analysis, which included partial least square (PLS) regression and principal component analysis (PCA). In brief, the form II content was estimated very accurately and reproducibly during the SMPT process not only by XRD but also by the DSC measurements. In addition, the form II content values were predicted very accurately by separate experiments at two designated time points. In a separate study, it was demonstrated that PCA could be employed to explain a complicated process such as SMPT mechanistically by several stages. © 2012 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 101:1578–1586, 2012</P>

肺高血壓症 合倂 心房中隔缺損症 : 開心術1例報告 Open Heart Surgery Under Hypothermic Hemodilution Perfusion with 5% Dextrose in Water

李寧均,金永洪,金相仁,申明秀 醫藥係社 1964 綜合 醫學 Vol.9 No.9

종격동 종양 47 치험례 : Report of 47 cases

이영,김종인,양기민,노준량,손광현,김종환,서경필,이영균 최신의학사 1971 最新醫學 Vol.14 No.10

Fourty-seven cases of mediastinal tumors originating in the mediastinum or metastasized from other organs were reviewed and classified on the basis of histopathological types and specific anatomical location in this department, during 13 years and six months period from Jan. 1959 to Jun. 1971. In thirty-seven cases, diagnosis was confirmed by histological findings. Range of age was 3 to 63 years and sex ratio was 1.4:1 male to female. In this series, metastatic mediastinal carcinomas of unknown pimary site were most frequent and thymoma ranked second in frequency, comprising 24.3% and 16. 2% of the total cases. The operative mortality was 3.1 There were histologically 11 different kinds of mediastinal tumors in this series.