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      • 계층화된 퍼지 인지도를 이용한 신뢰기반 경매시스템

        김현준,류정섭,권효석,조형래 경상대학교 생산기술연구소 2003 工學硏究院論文集 Vol.19 No.-

        This paper introduces trust measurement that is composed of trust variables and fuzzy cognitive map. The improved trust measuring method using a stratified FCM can be used to measure the level of risk involved in a specific auction transaction concerned. To reduce the auction transaction cost and time, the proposed system recommends a differentiated transaction protocol according to the risk based on trust measurement. In this system, trust measurement can also be applied for differentiated and varied auction services.

      • 도로판형교의 Life-Cycle Cost 최적설계

        조효남,민대홍,조준석 漢陽大學校 工學技術硏究所 2000 工學技術論文集 Vol.9 No.1

        본 연구에서는 강판형교에 대하여 총기대비용을 최소화하는 최적설계모델을 제안하였다. 총기대비용은 전체 공용기간을 고려하여 초기비용(설계비용, 개통전 검증재하시험비용, 건설비용), 유지보수비용 및 기대파괴비용을 포함하고 있다. 설계변수들에 대해 총기대비용을 최소화하는 문제로 정식화하였고, 거동제약조건은 휨파괴와 전단파괴의 형태로 되어 있다. 이러한 총기대비용 최적설계를 수행함으로써 효율적이고 합리적인 비용산정을 통해 총기대비용 설계의 근거를 제시하고 구조물 총기대비용에 관한 민감도 분석을 하였다. 수치해석을 통해 본 연구에서 제안된 총기대비용에 근거한 강판형교의 최적설계가 기존 초기비용 설계에 비해 훨씬 합리적이고 경제적인 설계가 될 것이며 향후 구조물 설계에서 추구해 나가야 할 차세대 성능기준 설계와 매우 밀접한 설계법임을 알 수 있다. This paper presents an optimum design model for minimizing the life-cycle cost (LCC) of steel plate girder bridges. The point is that it takes into account service life process as a whole, and thus the life-cycle costs include initial (design, testing, and construction) costs, maintenance costs and expected failure costs. The problem is formulated as that of minimization of expected total life-cycle cost with respect to the design variables. The performance constraints are considered in the form of flexural failure and shear failure. By processing the optimum LCC design the effective and rational basis is proposed for calculating the total LCC and the sensitivity analysis of LCC is performed. Based on a numerical example, it may be positively stated that the optimum LCC design of steel plate girder bridges proposed in this study provides a lot more rational and economical design, and thus the proposed approach will expedite the development of new concepts and design methodologies that may have important implications in the next generation performance-based design codes and standards.

      • 발달장애유아의 언어행동발달 연구

        김춘희,변찬석,서경희,유은정,이효신,전헌선,최성규 大邱大學校 特殊敎育·再活科學硏究所 2000 特殊敎育硏究 Vol.23 No.1

        본 논문은 발달장애유아 언어행동발달 컨텐츠 개발에 요구되는 기초연구로써 연구의 이론적 바탕을 확립하고자 하였다. 연구에 사용된 방법은 문헌조사 방법 및 현장 인터뷰기법을 병행하였다. 본 연구의 주된 목적은 크게 3가지로 구분된다. 첫째, 발달장애유아의 가정 내 교육 욕구를 분석하고자 하였다. 둘째, 발달장애유아의 언어발달 양상을 검토하고자 하였다. 세 번째 목적은 유아의 언어행동발달 컨텐츠 구성의 주요 지침을 설정하고자 하였다. 이상의 연구목적에 따른 연구결과를 요약하면 다음 몇 가지로 제시된다. 1.가정 내 부모-유아간 관계형성이 우선 고려 되어야하고, 이에 따른 상호작용은 발달적 애착형성이 가능한 방향으로 정립되어야한다. 2.발달장애유아의 언어행동발달양상을 검토한 결과에 따르면, Piaget는 언어행동발달에 있어 감각운동기적 환경탐색 기능을 강조하고 있고, 이는 현재까지 중요한 유아 발달의 기저로 정착되었다. 따라서, 발달장애유아의 언어행동발달을 위한 컨텐츠 개발 내용에 있어서도 이러한 기저에 충실함이 합리적이다. 3.발달장애유아들에게는 언어행동 양상의 갈래가 크게 운동장애 및 감각결함으로 나누어질 수 있으므로, 이 두 가지 갈래의 각기 다른 특성이 컨텐츠 구성에서 충분히 고려되어야한다. 4.자폐성과 같은 중증 전반적 발달장애 유아를 위한 언어행동발달 컨텐츠 구성에서 특히 고려해야 할 두 가지 요소는 모방행동기능과 반복단순훈련기능 향상으로 결론지을 수 있다. This article planed to establish the theoretical foundations of the research as a basic study needed for developing the contents of verbal(language) behavior development for the infants with developmental disabilities. The methods used in the study was previous literature researches and interviews with subjects. The purposes of the study were divided into three parts. First, it was to analyze the educational needs of the infants with developmental disabilities in home settings. Second, it was to review and discover the language patterns of the infants with developmental disabilities. The third purpose was to devise the major guidelines of their language development's contents. The results of the study were described as the followings. 1.The relationships between the infants with developmental disabilities and their parents and their interactions should move to build the developmental attachments between them. 2.According to the literature findings of their language development patterns, Piaget concentrated on the functions of sensory motor environmental exploring in the language behavior development. The functions have been settled down into the important foundation for the infants' development. Thus, it was resonable that the content's development of the language behaviors for the infants with developmental disabilities should based on the function addressed by Piaget. 3.The language behaviors' patterns of the infants with developmental disabilities generally were classified into motor disabilities and sensory defect(deficiency). Therefore, the two factors should be considered for the constructions of the contents. 4.Constructing the contents of the language behavior developments for the infants with severely pervasive developmental disabilities such as autism, the improvements of two functions, imitative behavior and repetitive simple training should be considered.

      • Treatment Efficacy and Safety of Tenofovir Disoproxil Fumarate-Based Therapy in Chronic Hepatitis B Patients for 3 Years: A Single-center Prospective Cohort Study

        ( Hyo Jun Ahn ),( Seok-hwan Kim ),( Myeong Jun Song ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Aims: To evaluate the efficacy and safety of Tenofovir (TDF)-based therapy in naïve and treatment-experienced chronic hepatitis B (CHB) patients for 3 years in a single-center Methods: A total of 148 CHB patients treated with TDF-based therapy at Daejeon St. Mary’s hospital were prospectively enrolled from Jan, 2013 to Jan, 2014. We compared the virological response and evaluated the safety of treatment-naïve and experienced CHB patients. Results: An overall complete virologic response (CVR) was achieved in 79.2 %, 84.0 %, and 90.8% of patients at week 48, 96 and 144, respectively. In the HBeAg (+) population (n=87), 88.5 % of patients achieved CVR, while in the HBeAg (-) patients (n=61), 94.2 % achieved CVR at week 144. In treatment-naïve populations (n=63), CVR of HBeAg positive patients (n=28) at week144 showed 96.2%. HBeAg loss or seroconversion rate at week 144 showed 25.0%, respectively. In treatment-naïve HBeAg negative CHB (n=35), CVR at week 144 showed 93.3%. In treatment-experienced populations (n=85), overall CVR showed in 74.4 %, 82.2 %, and 87.8% of patients at week 48, 96 and 144, respectively. In a subgroup analysis, CVR at week 144 was present in 100 %, 71.4%, 84.6%, and 94.4% of participants in the lamivudine-resistant (LAM-R) group, adefovir-resistant (ADV-R) group, multidrug-resistant (MDR) group, and suboptimal response group, respectively. Of note, 3-year CVR in MDR patients were improved compared to 2-year CVR (84.6% vs. 69.2%). In safety, there were no significant decrement of serum estimated glomerular filtration rate (eGFR), calcium, and phosphorus level. Aspartate aminotransferase to platelet ratio index (APRI) score were significantly improved during treatment. Conclusions: TDF demonstrated sustained viral suppression, a favorable safety, and no evidence of resistance development through 3 years of treatment. Significant improvement in underlying hepatic function including serologic markers of fibrosis was observed following 3 years of treatment.

      • SCOPUSKCI등재
      • SCOPUSKCI등재

        면역억제제로 유발된 범혈구감소증 후관해에 이른 궤양성 대장염 1예

        이준석 ( Jun Seok Lee ),박영숙 ( Young Sook Park ),김남인 ( Nam In Kim ),조윤주 ( Yoon Ju Jo ),김성환 ( Seung Hwan Kim ),이한효 ( Han Hyo Lee ),송문희 ( Moon Hee Song ),전대원 ( Dae Won Jun ) 대한장연구학회 2008 Intestinal Research Vol.6 No.1

        Azathioprine (AZA) is widely used for the treatment of inflammatory bowel disease. Bone marrow suppression is a common side effect with AZA treatment. However, data from AZA trials has indicated that a leukocyte count less than 5,000/mm3 was a good predictor of induction and maintenance of remission. Moreover, there is evidence that eradication of sensitized leukocytes by leukapheresis or bone marrow transplantation improves inflammatory bowel disease. We report a case of a patient who had a chronic relapse of ulcerative colitis requiring the frequent use of systemic steroids, but presented prolonged remission following AZA-induced severe pancytopenia. Also colonoscopy showed accelerated healing of diffuse active ulcers following just recovery from pancytopenia. (Intest Res 2008;6:85-89)

      • 온도와 변형 속도의 영향에 따른 방향성 단결정 전기강 박판의 소성 거동

        윤효준(Hyo Jun Yoon),하상렬(Sangyul Ha),이용석(Yong Seok Lee),성우석(Woo Seok Sung),박창수(Changsoo Park),김기태(Ki Tae Kim) 대한기계학회 2015 대한기계학회 춘추학술대회 Vol.2015 No.11

        Oriented silicon steel sheets having (110)[001] goss texture, are usually produced by cold rolling processes at a rolling reduction above 80%, which can develop surface crack and failure and eventually cause yield drop. Thus, it is essential to characterize a deformation behavior of silicon steels under various forming conditions. In this study, tensile tests were carried out at a strain rate 0.00038/s and in temperature range from room temperature to 300℃. A digital image correlation(DIC) method combined with the miniaturized tensile stage was used to characterize deformation field of the single crystal specimen. The initial and final crystallographic orientations of the tensile specimen were measured in a field-emission microscopy(FE-SEM) by using electron backscatter diffraction(EBSD). A strong dependency of the strain-rate and temperature on the stress-strain curves was observed as a typical characteristic of the body-centeredcubic(BCC) metals. Also, it is shown that even small misalignment of the crystallographic orientation can cause significant change of the stress level by changing the activation of slip system during plastic deformation.

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