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사람과 쥐에서 식이내 n6 와 n3 불포화지방산이 혈장 지질조성에 미치는 영향
박현서,남정혜,최주선 慶熙大學校 1991 論文集 Vol.20 No.-
To compare the plasma lipid-lowering effect of dietary n6 and n3 polyunsaturated fatty acids(PUFA) in human and rats, ten college women were divided into 5 groups and treated for 5 weeks with 1 week interval between treatments and subjects serving as their own controls. Male Sprague Dawley rats were divided into 3 groups and fed the experimental diets for 6 weeks. The experimental diets were corn oil diet for n6 linoleic acid, perilla oil diet for n3 α-linolenic acid and fish oil diet for n3 eicosapentaenoic acid (EPA) and docosahexaenoic acid(DHA). Dietary fat was supplied at 30% Cal and modified to give the total amount of satu-rated fatty acid(SFA) and monoenoic acid(MEA)at constant level. In human, there was no significant effect on plasma cholesterol (Chol)level by different PUFA. However, on a gramforgram basis, there was a trend that the decrease in plasma Chol was proportionate to the degree of fat unsaturation. HDL―Chol content was significantly increased only in fish oil diet but no change in the relative proportion of its chemical components of HDL. In rat, plasma Chol and HDL―Chol levels were significantly lowered by fish oil than corn oil and perilla oil. Plasma Chol―lowering effect in human and rats was greater by n3 EPA and DHA than n6 linoleic acid. Plasma triglyceride(TG)level in human was significantly lowered only in fish oil diet but no significant effect on the relative proportion of TG in VLDL. Plasma TG in rats was significantly decreased by both perilla oil and fish oil than by corn oil. Therefore, plasma TG―lowering effect was in the order of n3 EPA+DHA>n3 αlinolenic acid >n6 linoleic acid. In conclusion, perilla oil and fish oil which contain n3 series PUFA may have important nutritional benefit in the prevention and treatment of atherosclerotic disease.
Valproic Acid Regulates α-Synuclein Expression through JNK Pathway in Rat Primary Astrocytes
( Jung Nam Kim ),( Min Kyeong Kim ),( Kyu Suk Cho ),( Chang Soon Choi ),( Seung Hwa Park ),( Sung Il Yang ),( So Hyun Joo ),( Jin Hee Park ),( Geon Ho Bahn ),( Chan Young Shin ),( He Jin Lee ),( Seol 한국응용약물학회 2013 Biomolecules & Therapeutics(구 응용약물학회지) Vol.21 No.3
노인에 있어서 영양섭취실태와 인지능력과의 관계에 대한 조사연구
이현숙,김숙희,이재훈,강남이,한성숙,고양숙,김우경,박순옥,김연중 한국식생활문화학회 1992 韓國食生活文化學會誌 Vol.7 No.2
This study was carried out to find out the effect of dietary intake on cognitive function retardation in old age using dietary survey and cognitive function test. The subjects were 332 men of 50-94 years old and their activities of daily living were very similar. The cognitive function was tested by Mini Mental State Examination (MMSE)-K which was translated from MMSE, and the 24-hour recall method was used for dietary survey. Scoring of MMSE-K was a little different from MMSE, that is, in case of no education, one to four points were added to exclude the effect of education which has been considered as a confounder by many researchers. The number of subjects belonging to below 23 of MMSE-K score was increased by increasing age. Even though points were added in case of no education, the ratio of below 23 MMSE-K score group was diminished by increasing education. Therefore, education seems not to be a confounder but a independent variable on cognitive function. Income, past occupation, family type, self-evaluated health status did not play any effect on cognitive function significantly. On the other hand, the correlation between each nutrients and the score of cognitive function test showed that the more consumption of vitamin A and protein, the higher cognitive function score was obtained. In case of iron and Ca, even though it was not statistically significant, there was a tendency of increasing cognitive function score by increasing the intake of those nutrients. This study suggests that micronutrient intakes might be more related to cognitive function than macronutrients.
Computer-Aided Surgical Planning을 이용한 안면비대칭 III급 환자의 조기 양악 수술
최혜리(He-Li Choi),최태현(Tae-Hyun Choi),윤필영(Pil-Young Yun),이남기(Nam-Ki Lee) 대한치과교정학회 2024 대한치과교정학회 임상저널 Vol.14 No.1
Surgical-orthodontic treatment is aimed to restore occlusal function, harmonize a maxillofacial complex, and improve facial esthetics. As patients with dentofacial deformities desire an immediate improvement of appearance, surgery-first or surgery-early approach with minimal presurgical orthodontics has been reported. In addition, three-dimensional analysis using CBCT and computer-aided surgical planning (CASP) have made it possible to perform more accurate treatment plans for orthognathic surgery. This case report describes a successful surgery-early approach in a Class III patient with facial asymmetry. A 23-year-old male patient presented to our clinic with facial asymmetry and mandibular prognathism. The three-dimensional analysis showed mandibular deviation to the right side due to overgrowth of the left mandibular body, and the dentition presented canting of the occlusal plane to the left side with dental compensation of the maxillary right molars. Minimal presurgical orthodontic treatment was performed to improve arch coordination and eliminate premature contacts to achieve stable postoperative maxillo-mandibular relation. Afterward, canting correction and superior impaction of the posterior maxilla, and differential setback of the mandible were planned using CASP. Early bimaxillary surgery was performed with a 3D printed wafer. After a total of 20 months, the patient achieved a favorable facial profile and functional occlusion as planned. (Clin J Korean Assoc Orthod 2024;14(1):21-32)
AMFC system에서의 비정질 실리콘 박막의 결정화 특성
강구현(Ku Hyun Kang),이승재(Seung Jae Lee),김선호(Sun He Kim),이수경(Sue Kyeong Lee),남승의(Seung Eui Nam),김형준(Hyoung June Kim) 한국진공학회(ASCT) 2005 Applied Science and Convergence Technology Vol.14 No.1
a-Si을 poly-Si으로 결정화하는 전형적인 방법으로는 고상결정화(solid Phase Crystallization, SPC)가 있다[1-3]. 고상결정화는 균일한 공정특성과 생산비가 저렴하다는 장점이 있으나, 고상결정화 공정에서 높은 공정온도와 긴 공정 시간은 유리 기판의 손상으로 인해 적용되기 어렵다. 본 논문에서는 고상결정화의 저온공정과 짧은 공정시간을 위해 교번자장결정화(Alternating Magnetic field Crystallization, AMFC) 시스템 내에서 결정화하는 동안 교변 자장(Alternating Magnetic Field)을 적용하는 새로운 방법을 소개한다. 고상결정화의 경우, 열처리 시간은 570℃에서 24시간이 소요되었으나, 교번자장결정화의 경우, 같은 온도에서 20분이 소요되었다. A typical method for obtaining poly-Si films is the solid phase crystallization(SPC) of amorphous Si. Advantages of SPC are uniformity, process quality and low cost of production. However, high process temperature and long process time prevent the employment of SPC process on thermally susceptible glass substrate. In this paper, we propose a new method that applies an alternating magnetic field during crystallization annealing in an alternating magnetic field crystallization(AMFC) system for lowering process temperature and shorter process time of SPC. When we crystallized, in the case of SPC, annealing time is 24 hours at 570℃. But in the case of AMFC, annealing time is only 20 minutes at the same temperature.