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산업단지 및 일반생활 지역의 공기 중 톨루엔에 대한 개인노출 및 생체시료의 상관성 분석
이병준(Byoungjun Lee),허 정(Jung Heo),정다영(Dayoung Jung),김순신(Sunshin Kim),류현수(Hyeon-Su Ryu),최민지(Min-Ji Choi),솨이지엔페이(Jian-Fei Shuai),임성국(Sung-Guk Im),양원호(Wonho Yang) 한국환경보건학회 2017 한국환경보건학회지 Vol.43 No.4
Objectives: The purpose of this study was to assess the correlation relationship between personal exposure and urinary hippuric acid in biological monitoring for airborne toluene in an industrial complex and in general environments. Methods: Personal exposure to toluene and its metabolite, hippuric acid, in urine were simultaneously measured in occupational environments area near an industrial complex and in general environments. The study subjects were divided into three types: 137 workers who use organic solvents in the workplace, 210 residents living near a dyeing industrial complex, and 379 residents living in general environments. The toluene exposures of workers and residents were measured by a passive sampler for four days. The urine of participants was sampled when the passive samplers of personal exposure were collected. Results: The toluene and hippuric acid concentrations of workers were the highest, followed by the concentrations of residents living near a dyeing industrial complex and residents living in general environments. The coefficient of correlation between the concentrations of toluene and hippuric acid among workers was 0.749 (p<0.01) in the workplace. On the contrary, correlations between the concentrations of toluene and hippuric acid among residents living near a dyeing industrial complex and residents living in general environments were all not significant. The relationship between the concentrations of hippuric acid and toluene in three types could be described by the exponential growth model. Conclusions: This study analyzed the relationships between toluene exposure and the concentrations of hippuric acid in urine in high, middle, and low exposure environments, and could be described by the exponential growth model.
Lee, Inhye,Kim, Kuglae,Lee, Sumin,Lee, Seungjun,Hwang, Eunjin,Shin, Kihye,Kim, Dayoung,Choi, Jungki,Choi, Hyunmo,Cha, Jeong Seok,Kim, Hoyoung,Lee, Rin-A,Jeong, Suyeong,Kim, Jeongsik,Kim, Yumi,Nam, Hon Oxford University Press 2018 Journal of experimental botany Vol.69 No.15
<▼1><P>A missense mutation of <I>KARRIKIN-INSENSITIVE2</I>, <I>KAI2</I><SUP><I>ply2</I></SUP>, compromises its ligand-binding activity, which subsequently impairs KAI2-signaling and multiple aspects of light-dependent responses.</P></▼1><▼2><P><B>Abstract</B></P><P>A smoke-derived compound, karrikin (KAR), and an endogenous but as yet unidentified KARRIKIN INSENSITIVE2 (KAI2) ligand (KL) have been identified as chemical cues in higher plants that impact on multiple aspects of growth and development. Genetic screening of light-signaling mutants in <I>Arabidopsis thaliana</I> has identified a mutant designated as <I>ply2</I> (<I>pleiotropic long hypocotyl2</I>) that has pleiotropic light-response defects. In this study, we used positional cloning to identify the molecular lesion of <I>ply2</I> as a missense mutation of <I>KAI2</I>/<I>HYPOSENSITIVE TO LIGHT</I>, which causes a single amino acid substitution, Ala219Val. Physiological analysis and genetic epistasis analysis with the KL-signaling components <I>MORE AXILLARY GROWTH2</I> (<I>MAX2</I>) and <I>SUPPRESSOR OF MAX2 1</I> suggested that the pleiotropic phenotypes of the <I>ply2</I> mutant can be ascribed to a defect in KL-signaling. Molecular and biochemical analyses revealed that the mutant KAI2<SUP>ply2</SUP> protein is impaired in its ligand-binding activity. In support of this conclusion, X-ray crystallography studies suggested that the <I>KAI2</I><SUP><I>ply2</I></SUP> mutation not only results in a narrowed entrance gate for the ligand but also alters the structural flexibility of the helical lid domains. We discuss the structural implications of the Ala219 residue with regard to ligand-specific binding and signaling of KAI2, together with potential functions of KL-signaling in the context of the light-regulatory network in <I>Arabidopsis thaliana</I>.</P></▼2>
The Relationship Between Young EFL Learners’ Vocabulary Knowledge and Listening Comprehension
Dayoung Joo(Dayoung Joo),Junkyu Lee(Junkyu Lee) 한국초등영어교육학회 2022 초등영어교육 Vol.28 No.3
This study investigates the degree to which an elementary school EFL learner’s level of second language (L2) vocabulary correlates to their L2 listening ability. The study aims to further identify whether or to what extent various measures of vocabulary knowledge predict the variance in L2 listening comprehension. In particular, the study focuses on the relatively unexplored area of phonological knowledge of vocabulary. Three phonological measures which tap into both vocabulary breadth and depth knowledge were adopted in this study: the receptive phonological vocabulary breadth knowledge (RVB), productive phonological vocabulary breadth knowledge (PVB), and phonological vocabulary depth knowledge (VD) measures. Twenty elementary school EFL learners participated in the study and were required to complete an L2 listening comprehension test, followed by three vocabulary knowledge tests. Correlation analysis revealed that RVB most strongly correlated with L2 listening comprehension score (r = .77). Stepwise multiple regression analysis showed that the best fitting model which consists of RVB and VD could predict about 75% of the variance in L2 listening comprehension. The findings indicate that phonological vocabulary knowledge is a significant predictor of L2 listening ability of young EFL learners.
이준경(Lee Junkyoung),이남헌(Lee Namhun),하혜경(Ha Hyekyoung),이호영(Lee hoyoung),서창섭(Seo Changsub),정다영(Jung Dayoung),이진아(Lee Jinah),신현규(Shin Hyunkyu) 한국한의학연구원 2008 한국한의학연구원논문집 Vol.14 No.3
Objective: The purpose of this report was to provide the information about activity and safety of Ssanghwa-tang by analyzing domestic papers and theses about Ssanghwa-tang. Methods: Domestic papers and theses related to Ssanghwa-tang were reviewed and analyzed. These papers were then classified by year, experimental method, and activity subject. Results: The following results were obtained in this study. 1. The study of Ssanghwa-tang started from 1981 and continued steadily 1990s and it was decreased 2000s. 2. The paper of Ssanghwatang was entire domestic paper, 20 volumes. 3. In classified by experimental method and animal of Ssanghwa-tang paper, more than a half study used rat in vivo experiment. Furthermore clinical experiments were performed about anti-fatigue effect of Ssanghwa-tang and Ssanghwatang was proved a safety herbal medicine in acute toxicity experiment. 4. Decursin, glycyrrhizin, paeoniflorin were determined in Ssanghwa-tang by using HPLC analysis. 5. As these studies were classified by subject, papers related to anti-fatigue effect were most abundant by 7 papers. Besides there were several papers related to liver funtion, anti-inflammatory, alleviation, smooth muscle relaxation effect and so on. 6. According to experimental data, it is supported that Ssanghwa-tang was safety herbal medicine and it has a several activity about anti-fatigue, anti-inflammatory, alleviation, smooth muscle relaxation. Conclusion : Many study of basic science experiments and clinical experiments were performed and reported on Ssanghwa-tang in domestic journal. Ssanghws-tang is being used in various ways associating with anti-fatigue. anti-inflammatory. alleviation and smooth muscle relaxation. furthermore Ssanghwatang was proved a safety herbal medicine in acute toxicity experiment. However, studies on randomized controlled trials of Ssanghwatang need to be completed at the clinical level.
[PG-0001] Growth performance among the provincial Teak (Tectona grandis Linn.f,) in Myanmar
EiSandi Sett(EiSandi Sett ),Hye-Jin LEE(Hye-Jin LEE),Yang-Gil KIM(Yang-Gil KIM),Dayoung LEE(Dayoung LEE),Sunjeong KIM(Sunjeong KIM),Yoon-Ji Hahn(Yoon-Ji Hahn),Tae-Lim YEO(Tae-Lim YEO),Kyu-Suk KANG(Kyu 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-