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      • KCI등재

        Erratum to: Occurrence and surgical treatment of massive Morel-Lavallée lesion after large-volume liposuction: A rare clinical case

        Byeong Jun Kim,Chul Hoon Chung,이승준 대한미용성형외과학회 2020 Archives of Aesthetic Plastic Surgery Vol.26 No.1

        We have noticed an error in our published paper above. In the title, the order of “Byeong Jun Kim, Chul Hoon Chung, Seung Jun Lee” should be “Byeong Jun Kim, Seung Jun Lee, Chul Hoon Chung.” We sincerely apologize for the inconvenience that this may have caused.

      • 複合 韓藥劑 淸籬滋坎湯의 抗癌效果 및 作用機轉 糾明

        Cho, Kyung-Sam,Kim, Si-Young,Park, Jai-Kyung,Choi, Seung-Hoon,Chung, Se-Young,Yoon, Hwi-Joong 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Kyung Sam Cho¹Si Young Kim¹, Jai Kyung Park²,Seung Hoon Choi³,Se Young Chung⁴, Hwi Joong Yoon¹¹College of Medicine, ²East-West Medical Research Institute, ³College of Oriental Medicine, ⁴College of Pharmacology, Kyung Hee University,Seoul, Korea. The Anti-cancer Effect of Oriental Medicine Chung-Ri-Ja-Gam-Tang in the Mouse with Metastatic Lung Cancer. Proceedings of International Symposium on East-West Medicine, Seoul. 231-243, 1999.-The oriental medicine Chung-Ri-Ja-Gam-Tang is an herbal medicine which has been used for pulmonary diseases and known as having immune stimulatory effects. It has been known effective in lung cancer. So we studied the effects and the mechanisms of this herbal medicine it the mouse with metastatic lung cancer. The metastatic lung cancer of the mouse was produced with melnoma cell line(B16BL/6).5×10□/mouse tumor cells were injected intravenously to the CDF1 mouse via tail vein. The mice were divided 4 groups. The first group was treated with 50mg/kg extract of Chung-Ri-Ja-Gam-Tang per oral for 10 days after cancer cell injection, second group treated with saline after cancer cell injection, the third group with medicine without cancer cell, and the last group with saline only. After 10 days treatments some of the mice were scarificed and the lung and spleen was removed. The survival duration, weight change, the number of metastatic cancer nodule of the lung, the NK cell activity, the capacity of cytokines(INF-γ,INF-α,IL-2) production and the proliferation activities of mouse lymphocytes were measured. The surival times of the group 1 mice were longer and the weight loss was less than the group 2 significantly. The number of the metastatic nodule of the lung were decresed in the group 1 than the group 2. The production of INF-γ,was increase in group 2 than group 3 and 4, IL-2 production was increased in group 1 than group 2,3,4 significantly. There was no difference in TNF- α production and proliferation activity of lymphocyte in each group. The NK cell activity was significantly increased in group 1 than group 2,3,4. We conclude that the Chung-Ri-Ja-Gam-Tang has the effect of increasing the NK cell activity of the CDF1 mouse with metastatic lung cancer(B16BL/6). And it is suggested that the increased production of the IL-2 is the mechanisms of enhanced NK cell activity.

      • KCI등재후보

        Effect of Developmental Lead Exposure on the Expression of Hippocampal NMDA Receptor Subunit mRNA

        Kim, Tae-Wan,Chung, In-Sung,Bae, Jae-Hoon,Shin, Dong-Hoon,Lee, Mi-Young,Kim, Joon-Sik 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

        목적: in vivo 및 vitro에서 해마 신경세포의 발생단계별 NMDA 수용체 아단위 mRNA 발현에 대한 연 폭로 영향을 알아보고자 하였다. 방법: 흰쥐 해마 신경세포의 발생단계별 NMDA 수용체 NR2A, NR2B 아단위 mRNA 발현에 대한 연의 영향은 정상군과 연 폭로군의 출생 후 7일, 14일, 22일 흰쥐의 해마에서 in situ hybridization으로 mRNA 발현 정도를 densitometer로 측정하여 비교하였고, 연과 NMDA 의 세포독성은 해마 신경세포 일차배양 후 도립현미경을 이용한 형태학적인 관찰과 LDH 활성도를 이용하여 측정하였다. 결과: 연 과 NMDA 에 의한 세포독성에 대한 in vitro 실험에서 형태학적 소견과 LDH 활성도에서 해마 미성숙 신경세포와 성숙 신경세포사이의 차이가 있었으므로, 연과 NMDA 독성효과는 해마 신경세포의 발달 단계에 따라 차이가 있다. 정상군의 해마에서의 NR2A mRNA 발현은 출생 후 연령이 증가함에 따라 점진적으로 증가하였으나, NR2B mRNA 발현은 출생 후 연령이 증가함에 따라 점진적으로 증가하였으나 NR2B mRNA 발현은 연령의 증가에 따른 변화가 없었다. 연 폭로에 희한 NR2A mRNA 발현은 유의하게 감소하였으나(p<0.05), NR2B mRNA 발현은 변화가 나타나지 않았다. 만성적 연 폭로는 NR2A를 포함하는 NMDA 수용체를 감소시킬 수 있음을 알 수 있다. 결론: 연은 해마신경세포의 발생단계에서 NMDA 수용체 아단위 특히 NR2A mRNA 발현의 변화를 야기하여 시냅스 신호 전달에 영향을 나타냄을 알 수 있었다. Hippocampus

      • 원발성 폐암 환자의 생존율에 관한 보고

        김현태,이상무,어수택,박춘식,정성환,허승재,남충희,강창희,김용훈 순천향대학교 1994 논문집 Vol.17 No.4

        We analysed 404 patients with primary lung carcinoma who were treated at Soonchunhyang University Hospital from July, 1985 to september, 1993 in order to investigate the survival rate and epidemiolgical properties of primary lung cancer. They were 330 males and 74 females. The most prevalent decade was seventh. In terms of cell type, the squamous cell was 225 patients (55%), and adenocarcinoma, small cell, mixed type was 21%, 19%, 4%, respectively. Among non-small cell lung carcinoma, stage Ⅲa was the most prevalent one(92%). In case of small cell carcinoma, the limited stage was 64%. The 12-, 24-, 36- month survival rate of total patients was 57%, 31%, 22%, respectivley and median sruvival time was 15 months. The 36-month survival rate tended to be longer in non-small cell lung carcinoma than that of small cell lung cancer, but there was no difference between two groups, statistically. In non-small cell carcinoma, The 36-month survival rate and meidan survival time were longer in the stage Ⅰ and Ⅱ than those of Ⅲa, Ⅲb, Ⅳ (80% versus 38%, 22%, 0%, p<0.05). According to involvement of lymph node, the 36-month survival rate was longer in NO and N1 than those of N2, N3 (61.9%, 48.7% versus 17.7%, 17.3%, p<0.05). In small cell carcinoma, The 36-month survival rate and median survival rate were higher and longer in limited stage than those of extensive stage(16.1% and 13 month vs 10% and 8 month, p<0.05). In conclusion, we report here the incidence of primary lung carcinoma and the survival rate of paients with primary lung carcinoma who were treated in Soonchunhyang University Hospital.

      • SCOPUSKCI등재

        혈행화된 두개골 피판을 이용한 안와저 및 안와하연의 재건술 치험례

        정윤규,이훈범,김석원,봉정표,김균태,김주봉 大韓成形外科學會 1998 Archives of Plastic Surgery Vol.25 No.5

        A number of methods have been introduced for support the orbital floor following a maxillectomy without orbital exenteration or severe facial trauma. These methods including skin graft and muscular sling provided the unsatisfactory results, like as diplopia, orbital ptosis, enophthalmos and severe facial deformity. Therefore the bone and soft tissue reconstructions using microvascular free flaps were performed recently by many surgeons, but long time operation, donor site morbidity, postoperative large scar, and ptosis of the flap were pointed out as disadvantages of free flap reconstruction. Vascularized calvarial bone flap, a modified method of free calvarial bone graft, was adequate for reconstruction of the orbital floor and the infraorbital rim as a horizontal buttress, especially in case of poor vascular bed and postradiated state. The authors introduced the vascularized calvarial bone flap for the orbital floor and the infraorbital rim reconstruction in 3 cases of maxillectomy, and could be obtained satisfactory results aesthetically and functionally.

      • 유아체육'의 인터넷 검색 구조 분석

        김기영,이충훈 한국유아체육학회 2003 한국유아체육학회지 Vol.4 No.-

        본 연구는 현대인의 정보전달과 공유에 있어서 그 영향력이 대단히 큰 인터넷상의 '유아체육' 에 대한 검색결과를 조사·분석하여 나타난 문제점을 도출하고 향후 '유아체육'에 대한 보다 신속하고 정확한 정보검색의 방향을 논의하고 제시하는데 그 목적이 있다. 연구의 목적에 따라 국내 5대 검색 엔진의 사이트를 대상으로 하였으며, 최상위 카테고리(Category)에서 최하위 카테고리(Category)까지 조사하되, 최상위의 카테고리(Category) 또는 디렉토리를 분석한 결과 다음과 같은 결론을 얻었다. 1. '유아체육' 카테고리(Category) 형성의 미흡으로 정보검색 방향이 난해함. 2. 제2수준에서의 카테고리(Category) 형성 분류의 명확성이 결여됨. 3. 사이트 등록에 있어서의 '유아체육'에 대한 학문적 인식이 부족함. 상기와 같은 결과를 통해서 볼 때 '유아체육'검색 카테고리(Category) 형성의 방향성을 제시하자면, 첫째는 '유아체육' 웹사이트 제작자가 인터넷 검색 기능의 효율성을 제대로 인식해야 되겠으며, 둘째로는 검색 카테고리(Category) 분류에 있어서의 신중성과 세분화를 고려해야한다고 본다. 셋째는 '유아체육'웹사이트 개발자의 검색 등록시 유아체육 비 관련자에게의 위탁을 지양해야 한다는 것이고, 넷째는 '유아체육'의 학문적 위상 정립을 위한 끊임없는 연구 활동이 계속되어야 할 것이다. Internet have a effect on information-sharing and transmission of the modems. This research aims at deduction of a point at issue on checking and analyzing retrieval and then presenting more quick, exact information-retrieval about the infant physics of the future. According to the purpose of the research, five best search engines of domestic here in Korea are selected, from the investigated highest category to the investigated lowest, we draw the following conclusion of the best category or directory. 1. Because the form of infant physics category is insufficient, we have the difficulty in finding the direction of information search. 2. The clarity of category forming classification lacks from 2nd level. 3. There to be to site registration, the study recognition about an infant physics is insufficient. Through the above conclusion we can suggest the direction of infant physics search category from like that. First the infant physics web site manufacturer can recognize the efficiency of internet search function. Second they may consider the foresight and in search category classification departmentalization. Third when we register the manufacturer's infant physics. Web site, we should stop the consign to the non-relatived persons in infant physics. Forth we should continuously study to put the position of the infant physics highly.

      • KCI등재

        兩耳競聽法을 이용한 精神病患者의 大腦機能側向化

        金相勳,李廷南,楊秉換 大韓神經精神醫學會 1985 신경정신의학 Vol.24 No.2

        Lateralized functions of the cerebral hemispheres using the dichotic listening test were surveyed in subjects who consisted of 17 schizophrenic patients (10 males, 7 females), 18 bipolar disorder patients (10 males, 8 females) and 18 normal controls (10 males, 8 females). The results were as follows; 1. As to the comparison of total correct answers, there is no significant difference among each group and between both sex. 2. As to the comparison of correct answers according to the type of test, total subjects has significantly higher scores in word test (32.4±6.82) than in digit test (23.8±5.67), (p<0.01). And also, each group has the same results (p<0.01). 3. As to the comparison of correct answers recognized through the right ear or left one, total sucjects has significanly higher scores in right ear (30.9±5.51) than in left one (25.3±6.06), (p<0.05). 4. As to the correlation between the type of test and correct answers recognized through the right ear or left one, total subjects has significantly higher scores in word test than in digit test, in which both right and left (p<0.05). 5. Although there is no evidence of definitive ear asymmetry in both psychotic groups, bipolar disorder patients show a tendency of right ear dominance in digit test but it has no statistical significance.

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