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김상훈,서범천 대한근전도전기진단의학회 2017 대한근전도 전기진단의학회지 Vol.19 No.2
Objective: We wanted to test that LCD monitor can be used for pattern reversal VEPs with short response time instead of standard CRT monitor. Method: In 8 normal subjects with 16 eyes, VEPs were done with CRT and response time 1 ms LCD, 5 ms LCD monitors. Latencies of P100 waves and amplitudes of N75-P100 were compared for 3 different monitor groups. Results: Mean latencies of P100 waves were 111.8 ± 6.0 ms for CRT group, 115.8 ± 5.9 ms for 1 ms LCD group and 118.5 ± 6.2 ms for 5 ms LCD group and there was significant difference between latencies of CRT and 5 ms groups (p < 0.01, post-hoc analysis). Furthermore, latency difference value from CRT group minus LCD group on each subject also showed significant difference between CRT-1 ms LCD and CRT-5 ms LCD (p < 0.01). Mean amplitudes of N75-P100 didn’t show difference between 3 monitor groups. Conclusion: Latency of P100 wave with LCD monitor with 5 ms response time is longer than that with CRT monitor and LCD monitor with 1 ms response time also showed tendency of delay. These results suggest that the ready-made reference value should not be applied to the reference range with LCD monitor even though short response time.
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김상훈,김태범,김상헌,박흥우,송숙희,정재원,지영구,박상원,김미선,윤호주 대한천식알레르기학회 2018 Allergy, Asthma & Immunology Research Vol.10 No.1
The aim of this study was to examine the daily practice patterns of Symbicort® Maintenance and Reliever Therapy (SMART) in Korean asthmatic patients and to analyze clinical signs related to overuse. This study used an observational, multicenter, noninterventional, prospective, uncontrolled design for examining asthmatic patients prescribed SMART to assess the frequency and pattern of Symbicort® usage as a maintenance and reliever medication. The characteristics of patients showing signs of overuse (frequency of inhalation: 8 or more times per day) were also analyzed. Among the 1,518 patients analyzed, 1,292 (85.1%) completed the trial. The number of mean inhalations per day was 2.14±1.15; the number of patients who had at least 1 as needed usage (PRN) inhalation per day was 843 (55.5%); the mean frequency of PRN use was 0.25±0.67 inhalations per day. The number of patients who overused for at least 1 day was 260 (17.1%). In particular, young patients, patients with limited physical activity, and patients with nocturnal symptoms demonstrated high frequency of overuse. The frequency of overuse during SMART was not high in Korean asthmatic patients and the asthma status of follow-up outpatients improved overall. However, there is a need for careful education targeted toward younger patients, patients with limited physical activity, and patients with nocturnal symptoms owing to their tendency to frequently overuse.
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김상훈,최점기 한국기업경영학회 2006 기업경영연구 Vol.13 No.1
This study amis to provide the IS community with useful information on the development of performance evaluation model in the area of IS(information systems) research. To achieve the purpose of research, the follows are conducted. We begin with a general overview of theoretical paradigms, which are technical/functional, economic/financial, and interpretive/alternative paradigms, and present philosophical and methodological perspectives of them. Subsequently, a number of theoretical evaluation models with respect to IS effectiveness as well as the domestic and foreign cases with relation to informatization project and program are critically reviewed. Then, diverse approaches, methods and techniques related to performance evaluation systems are systematically integrated within the framework of 5W1H. Lastly, the conceptual performance evaluation model which consisted of 3 evaluation phases, 6 evaluation areas, and 22 evaluation items is developed through logically reasoning the interrelationship between components of the performance evaluation system. For researchers, the implications of this study can be utilized significant basis for constructing the theoretical framework of evaluation method and management of the informatization program. For practitioners, the integrated performance evaluation model developed in this study might provide the comprehensive and analytical view for the desirable performance management of the various types of informatization program. 본 연구는 정보화지원사업의 성과평가모형 개발에 관한 유용한 정보를 제공하기 위한 목적을 가지고 다음과 같은 절차에 의해 수행되었다. ① 기술적/기능적, 경제적/재무적, 해석적/대안적 성과평가 패러다임에 대한 고찰을 통해 이들의 철학적․방법론적 관점을 비교․분석하였다. ② 정보시스템 효과평가와 관련된 이론적 모형을 비롯하여 실무분야에서 활용되고 있는 국내․외 평가사례에 대한 비판적 분석을 통해 기존의 정보화성과평가체계 구축․운영상의 문제점 및 한계점을 살펴보았다. ③ 이상적 성과평가모형이 갖추어야할 접근방법, 방법, 기법, 절차 등을 체계적으로 통합시킨 5W1H기반의 성과평가체계를 정립하였다. ④ 성과평가체계의 제구성요소들간의 상호관계에 관한 논리적 추론을 통해 3개 평가시점, 6개 평가영역, 22개 평가항목으로 구성된 개념적 성과평가모형을 개발하였다. 본 연구의 결과는 정보화지원사업의 성과관리 및 평가를 위한 이론적 프레임워크를 구성하기 위한 유용한 기준으로 활용될 수 있다는 이론적 의의를 가지며, 실무적인 측면에서도 다양한 유형의 정보화지원사업의 바람직한 성과관리를 위한 포괄적이고 분석적인 시각을 제공해 줄 수 있다는 기여점을 가진다.
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벡터제어를 적용한 엘리베이터 도어용 유도전동기 구동 시스템 개발
김상훈,박내춘 江原大學校 産業技術硏究所 2009 産業技術硏究 Vol.29 No.A
Recently, a Elevator system is specially important in human life. Also a elevator door is important to a elevator system. In this paper, induction motor drive system using vector control was developed with high performance for elevator door system. For this, velocity pattern generation method was proposed. The proposed system is verified by experimental result with 400[w] induction motor drive system for the elevator door.
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GLCCI1 is a novel component associated with the PI3K signaling pathway in podocyte foot processes
김상훈,김현정,김찬화 생화학분자생물학회 2016 Experimental and molecular medicine Vol.48 No.-
Podocyte foot processes are interdigitated to form the slit diaphragm and are crucial for the glomerular filtration barrier. Glucocorticoid-induced transcript 1 (GLCCI1) is transcriptionally regulated, but its signaling pathway in podocytes is unknown. The main objective of this study was to investigate the regulation of podocyte foot process proteins and to investigate the role of GLCCI1 in the phosphoinositide 3-kinase (PI3K) pathway using high glucose-induced podocytes and streptozotocin-induced diabetic rats. In podocytes and rat kidneys, GLCCI1 was found to be highly specific for the glomerulus and podocyte foot processes similar to other podocyte-specific proteins (nephrin, podocin, synatopodin and podocalyxin) based on reverse transcription-PCR, western blotting, immunofluorescence and immunoelectron microscopy analyses. In addition, the decrease in the GLCCI1 expression level under hyperglycemic conditions was restored by treatment with a PI3K inhibitor (wortmannin). Immunofluorescence analysis confirmed that GLCCI1 colocalized with nephrin and synaptopodin both in vivo and in vitro. Finally, immunoelectron microscopy data from streptozotocin-induced diabetic rats showed that GLCCI1 also localized in podocyte foot processes. Hence, GLCCI1 is a component of podocyte foot processes, and its expression appears to be regulated via the PI3K pathway.
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해방 직후 반공 교육과 국사교과서에서 사회주의 관련 서술 삭제
김상훈 역사학연구소 2018 역사연구 Vol.- No.35
The independence movement was developed by Koreans with diverse ideologies,and socialists were more actively involved in the independence movement. However,students could not learn about socialism and the socialist independence movementin Korean history textbooks. Research continues on why descriptions of socialismwere excluded from Korean history textbooks, but they did not focus on the perioddirectly after liberation(1945~1950). The U.S. military government used education for the construction of an Americandemocratic nation and established a curriculum that included Korean history in thesocial studies. However, the U.S. military did not completely control Korean historytextbooks. Therefore, one can check the descriptions of socialism in textbookscompiled during the period of U.S. military government. The Rhee Syngman’sgovernment, which was established in August 1948, promoted democratic nationaleducation. However, democratic national education was a tool to push the nationalpolicy of anti-communism. The Rhee Syngman’s government purged left-wing teachers and established the student national defense corps(Hakdohokukdan) toformed a foundation to spread anti-communist education in schools. He also orderedthe government to cancel the authorization of textbooks or delete the contents oftextbooks that are hindering the promotion of national policy. This paper analyzedthe history textbooks of Lee Byungdo and Son Jintae. Through this can confirm thatsocialism narrative have been deleted and that a statement that can support thelegitimacy of the Rhee Syngman’s government has been added. In the end, theKorean history textbook, created through the approval of the Rhee Syngman’sgovernment in 1950, became the prototype of the political-tooled Korean historytextbook by strengthening and expanding anti-communism and anti-North Koreaawareness. 독립운동은 다양한 사상을 가진 한국인들에 의해 전개되었고, 사회주의자들은더욱 적극적으로 독립운동에 참여하였다. 하지만 국사교과서를 통해서는 사회주의와 사회주의자들의 독립운동에 대해 알 수 없었다. 국사교과서에 사회주의 관련 서술이 배제된 이유에 대해선 연구가 지속되고 있지만, 미군정과 이승만 정부가 수립된 해방 직후(1945~1950) 시기에 집중해서 살펴보지는 않았다. 미군정은 미국식 민주주의 국가 건설을 위해 교육을 활용하였고, 국사를 사회생활과에 포함시킨 교육과정을 수립하였다. 하지만 미군정은 완벽하게 국사교과서를 통제하지 못했고, 미군정기 발행된 국사교과서에서 사회주의 관련 서술을찾아볼 수 있다. 1948년 8월 수립된 이승만 정부는 민주주의 민족교육을 표방했다. 하지만 민주주의 민족교육은 반공이라는 국가 정책을 추진하는 도구였다. 이승만정부는 좌익 교원을 숙청하고 학도호국단을 창설하여 학교에서 반공 교육을 확산할 수 있는 토대를 만들었다. 그리고 국책에 어긋나는 모든 사상을 배제한다고 언명하고 교과서를 재검정하여 검정 취소하거나 관련 내용을 삭제했다. 본고에서는 1950년 검정을 통과한 이병도, 손진태의 국사교과서와 이들이 미군정기에 편찬한 교과서를 비교 검토하였다. 이를 통해 사회주의 관련 서술이 삭제되고, 이승만정부의 정통성을 뒷받침 할 수 있는 서술이 추가되었음을 확인하였다. 결국 이승만 정부 때인 1950년 검정을 통해 만들어진 국사교과서가 이후 반공과 반북 의식을강화하고 확대하며 정치도구화 된 국사교과서의 원형이 되었다.
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