대학생의 성교육 효과측정을 위한 기초 연구

장순복,최연순,강희선,박소미,Chang, Soon-Bok,Choi, Yun-Soon,Kang, Hee-Sun,Park, So-Mi 대한간호협회 1997 대한간호 Vol.36 No.2

This study was performed to provide preliminary data for the development of a useful instrument to measure the effect of sex education. The study was conducted with the voluntary participation of 155 college students enrolled in the course "Sexuality and Relationship" at Y university in Seoul. At the end of that course, they were asked to write freely about the change they had experienced on sexuality. All meaningful statements were elicited and classified into 7 categories; "Change of Knowledge", "Enlightenment", "Change of Attitude on Sexuality", "Buildup of Ability", "Buildup of. Identity", "Change of Emotion", "Change of Behavior:' There were significant changes in the areas of knowledge(28. 6%), enlightenment(27.4%), and attitudes(20.3%) about sexuality among these 7 categories. The Change of Knowledge category consists of 3 areas: "concretion of knowledge", "increase of information", and "correction of misunderstanding." In the category of Enlightenment, total 12 areas are included: "sex role", "erception of lack of knowledge", "importance of family", "life plan", "parent role", "value of life", "equality", "sexual autonomy", "importance of sexuality", "freedom of sexuality", "perception of sexual problem", and "meaning of love." The Attitude Change category consists of 8 areas. These are "being natural", "being progressive", "being sensitive", "being truthful", "being expressive", "being cautious", "being responsible", and "being confident". The category of Buildup of Ability includes 4 areas: "problem solving", "sex education", "relationship", and "communication". The category of Buildup of Identity includes "sexual identity", and "value of sexuality". The Emotional Change category includes 3 areas: "positive feeling", "negative feeling", and "breaking from negative feeling on sexuality". The Behavior Change category includes "sex-related behavioral change". In conclusion, up to now most researches on sex education effect measures only changes of knowledge, attitude, and behavior. But we believe the changes in "Enlightenment", "Buildup of Ability", "Buildup of Identity", "Change of Emotion", should be included in addition to knowledge, attitude, and behavior in the development of an instrument to measure the sex education effects. And the effect of sex education should measure the degree of learning of autonomy, enlightenment, and ability of behavior and so on rather than studying the simple changes in sexuality.enment", "Buildup of Ability", "Buildup of Identity", "Change of Emotion", should be included in addition to knowledge, attitude, and behavior in the development of an instrument to measure the sex education effects. And the effect of sex education should measure the degree of learning of autonomy, enlightenment, and ability of behavior and so on rather than studying the simple changes in sexuality.ng the simple changes in sexuality.

白鼠 肝障碍에 對한 補肝湯 瀉肝湯의 效果에 關한 實驗的 硏究

洪茂昌,李學仁,金完熙 慶熙大學校韓醫科大學韓醫學硏究所 1983 慶熙韓醫大論文集 Vol.6 No.-

Brain Topological Correlates of Motor Performance Changes After Repetitive Transcranial Magnetic Stimulation

Park, Chang-hyun,Chang, Won Hyuk,Yoo, Woo-Kyoung,Shin, Yong-Il,Kim, Sung Tae,Kim, Yun-Hee Mary Ann Liebert 2014 Brain connectivity Vol.4 No.4

<P>Repetitive transcranial magnetic stimulation (rTMS) influences the brain temporally beyond the stimulation period and spatially beyond the stimulation site. Application of rTMS over the primary motor cortex (M1) has been shown to lead to plastic changes in interregional connectivity over the motor system as well as alterations in motor performance. With a sequential combination of rTMS over the M1 and functional magnetic resonance imaging (fMRI), we sought changes in the topology of brain networks and specifically the association of brain topological changes with motor performance changes. In a sham-controlled parallel group experimental design, real or sham rTMS was administered to each of the 15 healthy subjects without prior motor-related dysfunctions, over the right M1 at a high frequency of 10 Hz. Before and after the intervention, fMRI data were acquired during a sequential finger motor task using the left, nondominant hand. Changes in the topology of brain networks were assessed in terms of global and local efficiency, which measures the efficiency in transporting information at global and local scales, respectively, provided by graph-theoretical analysis. Greater motor performance changes toward improvements after real rTMS were shown in individuals who exhibited more increases in global efficiency and more decreases in local efficiency. The enhancement of motor performance after rTMS is supposed to be associated with brain topological changes, such that global information exchange is facilitated, while local information exchange is restricted.</P>

입원환자 낙상예방 프로그램에서 근력운동의 효과: 낙상 고위험군 노인환자를 중심으로

이현옥 ( Hyun-ok Lee ),이병화 ( Byung-hwa Lee ),이창희 ( Chang-hee Lee ) 한국보건정보통계학회(구 한국보건통계학회) 2017 보건정보통계학회지 Vol.42 No.4

Objectives: The purpose of this study is to analyze the changes in the indices of body muscle strength, the indices of muscle strength associated with physical balance, and index of the pain relief between the intervention group who performed the muscle strength exercise and control group who not performed the muscle strength exercise. The study period was from September 7, 2016 to May 12, 2017, and it was conducted after receiving Institutional Review Board approval. Methods: Among 40 participants who were recruited in this study, the final analysis subjects were a total of 39 people, excluding the one people who dropped out during the 2-week. For analysis, the changes were compared with baseline and after two weeks by comparing three types of body muscle strength indices, four types of physical balance indices, and one type of pain relief index. Finally, we analyzed whether there is a difference between the groups in the each changes. Results: In the body muscle strength index change analysis, the change of muscle mass relative to weight was not statistically significant, but the difference between the groups regard to change was statistically significant (p<0.05). The lower body strength and the bone mineral were statistically significant in both the intervention and control group, but the difference between the groups regard to change was not statistically significant. In the index of muscle strength associated with physical balance change analysis, the intervention group showed improvement much higher in the right arm, left arm, right leg, and left leg of muscle mass than the control group. Also, the muscle mass of the right arm and the left arm was statistically significant in the analysis of the difference between the groups regard to change (p<0.05). Analysis of changes in pain relief index showed that the intervention group showed significantly improvement higher than the control group, and the difference between the groups regard to change was statistically significant (p<0.05). Conclusions: In the elderly patients in the hospital where the fall prevention program was provided, it was concluded that the intervention group higher improved the muscle strength associated with physical balance and the pain relief compared with the control group.

한방 이화주의 미백 및 피부 주름 개선 효과

이상진(Sang-Jin Lee),권이영(Yi-Young Kwon),조성원(Sung-Won Cho),권희숙(Hee-Suk Kwon),신우창(Woo-Chang Shin) 한국식품영양과학회 2013 한국식품영양과학회지 Vol.42 No.4

본 연구에서는 한방이화주의 피부 생리기능 활성을 알아보기 위해 70% EtOH 추출물의 피부 미백, 주름 개선 및 항염증 효과를 조사하였다. HEE은 tyrosinase 활성 억제 및 tyrosine을 기질로 melanin이 형성되는 pathway에 관여하는 주요한 인자인 TRP-1과 TRP-2를 저해하는 작용 기전을 통해 피부 색소침착의 주요 원인 물질인 melanin 생합성을 농도 의존적으로 저해하는 것을 확인하였다. HEE은 피부진피 내 피부 탄력을 유지하는 elastin을 분해하는 효소인 elastase의 활성을 저해하였고, 피부의 keratinocyte가 생성분비하는 MMP-2와 MMP-9의 단백질 발현과 proteolytic 활성을 억제하여 노화에 따른 피부 주름 생성 억제할 수 있는 가능성을 확인하였다. 또한 세포 독성 없이 LPS에 의해 유도된 염증 반응을 50% 저해하는 HEE의 농도(IC50)는 24.9 μg/mL이며, 50 μg/mL 농도로 처리하였을 때 염증 반응 저해 효과가 70%로 높은 효과를 가지는 것을 확인하였다. 이상의 결과를 종합하면 HEE의 피부 미백, 주름 개선 및 항염증에 우수한 효과를 나타내고 있으므로 기능성 화장품의 주요한 소재로 이용 가치가 높을 것으로 사료된다. Extrinsic skin aging is characterized by the loss of skin tone and resilience, irregular pigmentation, and deep wrinkles. The aim of this study was to investigate the effects of Ehwa Makgeolli containing oriental herbs (Glycyrrhiza uralensis Fisch., Lycium chinense MILL., Morus alba L., and Saururus chinensis Baill) on skin whitening and wrinkling in human skin cells. We prepared Makgeolli extracts (HEE) with 70% ethanol. HEE significantly inhibited in vitro mushroom tyrosinase activity and reduced the cellular and secreted melanin content of mouse melanoma melanocytes (B16F1 cells). HEE down-regulated the protein expression of tyrosinase related protein (TRP)-1/-2, a key player in melanogenesis. Treatment with HEE in human keratinoctyes (HaCaT cells) inhibited the proteolytic activities of matrix metalloproteinase (MMP)-2/-9 in a dose-dependent manner and dramatically reduced the expression of MMP-2/-9. In addition, HEE attenuated lipopolysaccharide (LPS)- induced nitric oxide production in murine macrophages (RAW264.7 cells). These results indicate that HEE may be a great cosmeceutical ingredient for its whitening, anti-wrinkle, and anti-inflammatory effects.

Putting Climate Change into Water Resource Management: Adaptation Efforts in the U.S., U.K., Canada, Australia, and the Netherlands

( Hee Jun Chang ),( Jon Franczyk ),( Deg Hyo Bae ) 한국환경정책평가연구원 2006 환경정책연구 Vol.5 No.4

기후변화가 지역의 수자원에 영향을 미칠 것으로 예상됨에 따라 수자원 관리자들은 이에 대응한 적응전략을 수립하는 것이 필요하다. 이에 본고에서는 미국, 영국, 캐나다, 오스트렐리아, 네덜란드의 적응관리의 실태를 검토하였다. 이들 나라들은 현재의 수자원 관리관행, 제도적 장치, 기후변화의 잠재적 수자원 영향에 따라 매우 상이한 적응관리를 하고 있다. 이들 나라들의 비교연구를 통하여 기후변화에 따른 한국에서의 지속가능한 수자원 관리를 위한 정책적 관련성을 도출하였다. As global climate change is expected to influence regional water resources, water resource managers need to establish adaptive management to cope with climate change. We examined adaptive management efforts in the US, UK, Canada, Australia, and the Netherlands. Each country is implementing different levels of adaptation efforts based on current water management practices, institutional arrangements, as well as the varying degree of water availability, current climate effects and expected climate change effects. Based on the comparison of these countries, we suggest policy implications for the sustainable water resource management of Korea under climate changes.

Carotenoids 식이와 알코올이 혈액학적 성분과 간조직에 미치는 영향에 관한 연구

조만희,김연선,이상한,우기민,장예진,김창세 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

Alcohol is well known agent which can damage the human tissues such as liver via stimulating lipid peroxidation and storage, denaturation of macromolecules, and inhibiting protein metabolism. On the other hand, carotenoids in addition to vitamins A, C, E and lipoic acid, play important roles in protecting these oxidative damages as well as preventing the production of free radicals. This study was carried out to elucidate the precise effects of alcohol administration into rats on the antioxidative functions of dietary carotenoids and isolated β-carotene, and to find out any parameters to uncover more detailed biochemical mechanisms of these agents. For these purposes, two different approaches were performed: 1) examination of the changes in hematological parameters (e.g., total proteins, A/G ratio, ALT/AST et. al) and statistical correlations among inter- and intragroups, 2) examination of the histopathological changes by an electron microscope. The results were analyzed and summarized as following; (1) Carrot diet for one week caused a slight increase in albumin. A/G ratio and AST levels, and a slight decrease in ALT, ALP, BUN and uric acid levels. Two-week alcohol administration following carrot diet increased total proteins, albumin A/G ratio and BUN levels. However, both groups were shown to have little significant changes in cholesterol concentrations. (2) Cheese diet for one week caused a significant increase in total proteins, albumin, AST, ALP, uric acid and total cholesterol levels, and a significant decrease in A/G ratio and glucose concentrations. However, two-week β-carotene diet following cheese intake increased total proteins albumin, A/G ratio, BUN and total cholesterol levels, whereas AST, ALT, ALP and uric acid levels were decreased. (3) Alcohol administration for one week caused an increase in AST activities and a decrease in total proteins, albumin, ALT, ALP and BUN levels. A successive β-carotene diet following alcohol administration increased total proteins, albumin, ALT, ALP and BUN levels, whereas decreased AST and uric acid levels. However, there were not significant changes in A/G ratio, glucose and total cholesterol levels in both groups. (4) β-carotene diet for one week caused a slight increase in albumin, glucose, AST and uric acid levels, and a slight decrease in ALP and BUN levels. Two-weeks alcohol administration following β-carotene diet increased albumin, glucose, BUN and total cholesterol levels, whereas decreased AST, ALT, ALP and uric acid levels. (5) Although the pathological investigation on the liver did not reveal significant changes, cheese diet group (CH-BC/1-CH) was shown to have some lipid deposits. Some results were unexpected and different from typical hematological changes shown by other researchers. Nonetheless, these results strongly suggest that the liver damage or hepatism caused by alcohol intake affects many kinds of biochemical metabolisms, which results in significant changes in many hematological parameters. In addition, dietary carotenoid and isolated β-carotene were shown to have protective roles against the biochemical changes by alcohol intake.

트라이애슬론 스포츠폭력 사건에 투영된 트라이애슬론 선수들의 경험과 인식

김희주 ( Kim Hee-ju ),장덕선 ( Chang Duk-sun ) 한국융합과학회 2022 한국융합과학회지 Vol.11 No.8

연구목적 본 연구는 故 최숙현 선수의 희생이 헛되지 않기를 바라는 마음으로 시작되었다. 연구대상은 2020년 스포츠폭력에 의해 고인이 된 최숙현 선수의 사망사건을 직·간접적으로 경험한 철인3종경기 선수 30명이다. 연구방법 연구방법은 내러티브의 3차원적 공간 중 개인적·사회적 차원과 내적·외적 지향에 중점을 두고, 연구 참여자의 스포츠폭력에 대한 인식과 경험을 개방형 질문으로 조사하였다. 이 후 추가적 심층면담을 실시하였다. 특히 참여자들이 현역선수들이기 때문에 연구참여중단의 가능성과 익명성을 보장하였다. 연구자는 25년간 트라이애슬론 선수로 활동을 하였으며, 직접 피해자이기도 하다. 결과 자료의 귀납적 범주화 결과, 스포츠폭력 사건에 대한 인식에는 기본신념 붕괴, 제도적 문제, 우려, 감정 등이 나타났다. 인지된 내적 변화에는 부정적 영향 없음, 제도적 문제, 간접 트라우마 등이 나타났다. 인지된 외적 변화로는 부정적 영향 없음, 간접 트라우마 등이 나타났다. 지각된 변화로는 변화와 기타로 나타났다. 변화의 시발점은 처벌에 대한 생각, 감정, 제도적 문제 등이 도출 되었으며 변화의 방향성으로는 2차 피해 우려, 확실한 변화 요구, 제도적 해결책 필요 등으로 나타났다. 결론 결과를 토대로 트라이애슬론의 스포츠폭력 사건에 대한 답변을 시간의 흐름 순으로 정리하여 새로운 패러다임 모형을 제시하였다. Purpose This study was started with the hope that the sacrifice of the deceased player, Sook-Hyun Choi, would not be in vain. The subjects of this study were 30 Korean triathletes who directly or indirectly experienced the case of Choi Sook-hyeon, who died of sports violence in 2020. Methods The research method focused on personal and social dimensions and internal and external orientation among the three-dimensional space of the narrative, and conducted an open-ended questionnaire about the research participants' perceptions and experiences of sports violence. After that, additional in-depth interviews were conducted during the analysis process to collect data. In particular, since the participants are active players, the possibility of discontinuation of research participation and anonymity were guaranteed in consideration of ethical issues that may arise from this. In addition, the research was conducted in consideration of the fact that the researcher had been active as a triathlete for 25 years and was also a victim. Result As a result of inductive categorization of the collected data, the perception of sports violence incidents revealed a breakdown of basic beliefs, institutional problems, concerns, and emotions. There were no negative effects on perceived internal changes, institutional problems, and indirect trauma. As for the perceived external changes, there were no negative effects and indirect trauma. Changes and others were perceived as changes. As the starting point of change, thoughts, feelings, and institutional problems about punishment were derived. As for the direction of change, concerns about secondary damage, a clear demand for change, and the need for an institutional solution were shown. Conclusion A new paradigm model was presented by arranging the responses to the three types of sports violence cases in the order of time flow.

알코올 투여로 온 흰쥐의 혈액성분의 변화와 간조직 손상과의 상호관계에 관한 연구

조만희,김창세 순천향대학교 1986 논문집 Vol.9 No.2

The white rats were divided by 3 groups; 0.6g(group A), 1.8g(group B) and 4.8g(group C) of alcohol per kg of body weight. The ethanol has been administered to the stomach with a polyethylene catheter using 20% ethanol solution for 30 days. In 5 day interval from the begining, the white rats were sacrificed to collect sample for blood analysis and histopathological observation. And the following results were obtained. 1. The most variable changes of blood components to be influenced by alcohol administration were; alcohol concentration, activities of liver ADH and GOT, numbers of RBC and WBC, amounts of triglyceride and total cholesterol and α₂-globulin fraction. 2. The liver histopathological changes, depending on the amounts and feeding days from the alcohol administration, were observed; normal finding on 1st to 10th and after then mild ballooning degeneration, necrosis of hepatic parenchymal cells in portal tract, mild infiltration of lymphocytes and fats degeneration. 3. The interrelationship between changes of blood components and histopathological damage of liver were coincide on 10th to 20th in the aspects of remarkable changes. From the above summary the amount and duration of ethanol-administration were influenced on changes of blood components and histopathological findings of liver while the early period usually 1st to 10th day was observed no more pathological changes but after then significants changes observed. From the above result there were suggested that the alcohol retaining in the body in a long period were results to appear in biochemical metabolic change.

Ⅲ급 부정교합자의 양악 수술과 하악 편악 수술 시 연조직 변화에 관한 비교 연구

박영국,장인희,이영준 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.1

악교정 수술 시행 시 연조직 변화에 대한 대부분의 연구는 Ⅱ급 부정교합을 대상으로 하였다. 또한 수술 방법에 따른 연조직 변화에 대한 비교 연구가 부족하였다. 따라서 이 연구는 골격성 Ⅲ급 부정교합자에서 상악골 전진술과 하악골 후퇴술을 동시에 시행한 양악 수술과 하악골 편악 수술 시행 시, 경조직과 연조직 측모 및 연조직 두께의 변화를 관찰하고, 수술 전후 변화의 상관성을 산출하며, 경조직 변화에 수반하는 연조직 변화의 비율을 산출하여 교정-악교정 수술 복합 치료 계획 수립과 결과의 예측에 이용하고자 시행되었다. 경희대학교 치과병원 교정과에 내원하여 골격성 Ⅲ급 부정교합자로 진단받은 환자 52명을 대상으로 하여, Le Fort I osteotomy를 이용한 상악골 전방이동술과 시상분할골절단술을 이용한 하악골 후퇴술을 시행한 양악 수술군 26명과 하악골 후퇴술만을 시행한 편악 수술군 26명으로 구분하여, 수술 전후 측모두부방사선규격사진을 계측, 분석하여 다음과 같은 결과를 얻었다. 양악 수술군은 골격 변화량의 72.4% 비율로 상순 부위 연조직의 전방 이동을 보였으며, 편악 수술군은 통계적으로 유의한 변화를 보이지 않았다. 비순각은 양악 수술군에서 편약 수술군에 비해 더 크게 증가하였다. 이순각은 편악수술군에서 더 크게 감소하였다. 하악골의 후방 이동에 따른 연조직 pogonion의 후방 이동은 양악 수술군에서 98%, 편악 수술군에서 109%로 편악 수술군에서 더 크게 나타났다. 양악 수술군에서는 편악 수술군에 비하여 경조직의 변화에 수반하는 상순에서의 큰 변화가 나타났다. 편악 수술군에서는 상순의 변화는 미약하엿으며, 하순 및 이부의 변화가 양악 수술군에 비해 두드러지게 나타났다. Numbers of postulations lie on the difference of integumental changes with two major surgical remedies of one jaw vs. two jaw surgery in skeletal Class Ⅲ malocclusion. Accordingly it was the aim of the study to elucidate the skeletal profile changes with an accompanying disposition of soft tissues, consequently to yield the correlation and ratio of soft tissue changes with two types of surgical procedures, which in turn make it possible to predict the soft tissue outcomes by means of assembled regression equations. Cephalometric headfilms of fifry two adult skeletal Class Ⅲ comprised of 26 maxillary advancement by Le Fort I osteotomy and mandibular setback by sagittal split ramus osteotomy simultaneously (double jaw surgery, group A), 26 mandibular setback alone (one jaw surgery, group B) were statistically analyzed. Group A manifested 72.4% soft tissue advancement to skeletal changes in the upper lip area, while group B appeared to have no statistically significant changes. The nasolabial angle showed more increment in group A than in group B, whereas the mentolabial angle illustrated more reduction in group B. The backward movement of soft tissue pogonion to skeletal change revealed 98% in group A, and 109% in group B. The double jaw surgery group characteristically revealed remarkable integ umental change in the upper lip area, while the one jaw surgery had major effects in the lower lip and soft tissue pogonion areas.