비중격에 발생한 형질세포종 1례

백병준,김윤정 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Extramedullary plasmacytoma is a rare soft tissue malignancy composed of monoclonal plasam cells. The great majority of extramedullary plasmacytoma occurs in the head and neck region, mainly in the submucosa of the upper respiratory tract. The most frequently involved sites are the sinonasal / nasopharyngeal area. If histologic diagnosis of plasmacytoma is confirmed, all screening tests are necessary to rule out multiple myeloma. The treatment and prognosis are different according to sites where the extramedullary plasmacytoma is originated. We experienced a case of extramedullary plasmacytoma that arising from the nasal septum in a 65-year-old woman. The septal mass was totally removed endoscopically with no complication. The patient received postoperative radiotherapy(45 Gy.) At 1-year follow-up, the patient was doing fine with no sign of recurrence.

비용에서 상피 성장인자 수용체의 발현

백병준 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background and Objectives : Epidermal growth factor(EGF), mediated by its receptor(EGFR), is a potent stimulator of cell proliferation and differentiation. The purpose of this study is to evaluate the role of EGFR in the pathogenesis of nasal polyps. Materials and Method : Immunohistochemical stain was performed on 15 nasal polyp specimens obtained in patients who underwent endoscopic sinus surgery and 9 normal nasal mucosa from inferior turbinate. A monoclonal antibody recognizing an epitope of intracellular domain of EGFR was used in a streptavidin-biotin complex technique. Results : EGFR was expressed in 55.6% of normal nasal mucosa, and positive cells were noted mainly in epithelium and glands of lamina propria. In the epithelium which was stained, positive cells were localized mainly in upper layer in the form of coarse granule in the cytoplasm. In the glands which were stained, positive cells were found in the form of diffuse of coarse granule in the cytoplasm. EGFR was expressed in 53.3% of nasal polyps. The location and staining pattern of positive cells were similar to the findings of normal nasal mucosa. Conclusion : EGFR may not play a role in the formation and proliferation of nasal polyps.

이하선에 발생한 근상피종 1례

백병준 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

In a normal gland, myoepithelial cells are located between the epithelial cells and the basal larmina of acini and intercalated ducts. Myoepithelioma is rare, generally benign neoplasm that accounts for less than 1% of all salivary tumors. The most common locations of myoepithelioma of the head and neck are the parotid gland and the palate. Myoepithelioma resembles pleomorphic adenomas in its appearance and growth pattern. We experienced a case of myoepithelioma that arising in the parotid gland. The mass was removed with a margin of uninvolved tissue. Histologic features showed that the tumor was composed of spindle-shaped cells and plasmacytoid(hyaline) cells.

비중격에 발생한 화농성 육아종 1례

백병준,정윤영,오천환 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

Pyogenic granuloma is a well circumscribed, soft tissue tumor of inflammatory rather than neoplastic nature. It arises from the connective tissue of the skin or mucous membrance. Pyogenic granuloma arising from the nasal septum is an uncommon benign vascular tumor and it is at times difficult to differentiate from the hemangioma or angiofibroma histologically. Recently the authors had experienced a case of Pyogenic granuloma arising from right side of the nasal septum which was treated by local excision and electrocauterization. We report this case with review of the literatures.

수직 채널내의 가열된 돌출 배열에서의 대류 열전달

趙秉守,白秉峻,朴福春 全北大學校 1996 論文集 Vol.41 No.-

An electronic circuit board was simulated by protrusions, which was heated by thin stainless foil attached on the surface, in a vertical channel. Natural and forced convection experiments were carried out in order to investigate the effects of channel spacing, gap between protrusions and number of rows of protrusion. In natural convection, the optimum channel spacing was found to be approximately 30mm regardless of the protrusion gap. For optimum channel spacing the heat transfer coefficients were converged to an asymptotic value after fourth row. The heat transfer coefficient for each row approaches to constant values for protrusion gaps larger than 10 mm. An experimental correlation has been suggested by using a modified Rayleigh number, based on the dimensionless characteristic length(G/L). In forced convection, the heat transfer coefficients were not merged to an asymptote until the fifth row and increased as channel spacing at the constant Reynolds number decreases.

알레르기 환자에서 MAST-CLA 검사의 의의

남해선,황규윤,,백병준,정윤영,오천환,조성란,박준수 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

To evaluate usefulness of application of MAST-CLA to indetify allergens, authors conducted MAST-CLA allergen-specific IgE assay and collected allergy related symptoms in 118 allergic patients diagnosed at Soonchunhyang University Chunan Hospital during October 1998 through January 2000. The results were as followings; 1. The mean (SD) age was 23.1 (±12.17) years old and teenagers accounted for 33.1% of patients. 2. The frequent allergic symptoms were sneezing (59.3%), rhinorrhea (53.4%), nasal stiffness (44.1%), itching sensation (24.6%), cough or sputum (16.1%), and eye symptom (8.5%) in order. 3. Among these subjects, 62.7% of patients revealed at least more than one specific allergen and 70.3% showed elevated total IgE levels by MAST-CLA. The three most frequent specific allergens were Dermatophagoides farinae (47.5%), Dermatophagoides pteronyssinus (45.8%), and house dust (30.5%). 4. While age was not significantly related to positive of both specific allergens and total IgE (P>0.05), sneezing and nasal stiffness were significantly associated with positive of specific allergen and total IgE, respectively (both P<0.05). 5. Total IgE increased with the number of specific allergens, but both specific allergen and total IgE were not significantly related to increases of allergic symptoms (P>0.05). In conclusion, our data suggest that MAST-CLA allergen-specific IgE assay is useful measure for identification of causative allergens in allergic patients, however, it is recommended that more specific allergic antigens should be determined and replaced or added to Korean inhalent panel of MAST-CLA.

새열기형의 임상적 고찰

김장묵,김대식,백승혁,한동렬,김희중,백병준,오천환 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

Background and Objectives : Branchial cleft anomalies are encountered rarely in clinical practice. We reviewed medical records of branchial cleft anomalies according to age and sex distribution, site distribution, characteristics of mass on physical examination, location of mass, preoperative diagnosis, type of branchial cleft cyst and report our experience with 25 cases of branchial cleft anomalies. Materials and Methods : A review of medical records was performed on 25 cases of branchial cleft anomalies diagnosed in pathologic report from January, 1990 to March, 2000. Result : Sex distribution was 11 male and 14 female, age distribution was most common in third decade which was 8 cases(32%). Site distribution was predominant in left side(13 cases), and in physical examination, the characteristics of the mass was nontender(76%), mobile(60%), soft(80%). The lesion site was submandibular area in 2 cases, upper 1/3 portion of sternocleidomastoid muscle(SCM) in 2 cases, middle 1/3 portion of SCM in 20 cases and parotid area in 1 case. The preoperative diagnosis was branchial cleft cyst in 16 cases, cervical lymphadenitis in 3 cases, tuberculous lymphadenitis in 3 cases, branchial cleft fistula in 1 case, dermoid cyst in 1 case and parotid mass in 1 case. Among 25 cases, first branchial cleft cyst was seen in 4 cases, second branchial cleft cyst in 20 cases and second branchial cleft fistula in 1 case. Conclusion : The clinical history of recurrent neck inflammatory episodes in young patients and nontender, mobile, soft neck mass should raise the suspicion of this entity. Investigation using CT scanning in combination with aspiration is useful. Treatment of all branchial cleft anomalies is complete surgical excision because there is lack of spontaneous regression, a high rate of recurrent infection, the possibility of other diagnosis, and rare malignant degeneration. Complete removal without complications depends on a good understanding of regional embryogenesis, a knowledge of the surrounding structure, and awareness of the different anatomical presentation.

기도 이물의 임상적 고찰

김영석,이승규,이민재,백병준,오천환 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

Aspiration of foreign bodies into the airway is a common problem in spite of efforts to educate the public and it can be sometimes fatal accidents. A retrospective study has been performed for 34 cases of airway foreign bodies, which were obtained from April 1994 to August 1998 at Chunan hospital of Soonchunhyang University. The results were as follows: 1) Among the 34 cases, 26 cases(76.4%) were under the age of 3. The ratio of male and female was 1.4:1. 2) The most common symptom after foreign body aspiration was intractable cough(38.2%). 3) Abnormal findings in the chest X-ray films were found 24 cases(70.6%) and the most common abnormal radiologic feature was combination of pneumonia and atelectasis(37.5%), followed by combination of pneumonia and emphysema(16.6%), pneumonia alone(16.6%). 4) The nature of foreign body was vegetables in 20 cases(58.8%), miscellaneous in 11 cases(32.4%), metals in 2 cases(5.9%) and plastics in 2 cases(5.9%). 5) By distribution of the location of foreign bodies, 26 cases(76.4%) were located in the main bronchus(20 cases in right side and 6 cases in left side), 5 cases were in trachea, 2 cases were in larynx and 1 case was located at carina level. 6) By duration of foreign body lodgement in the airway, 15 cases(44.1%) were found within 24 hours, 9 cases(26.5%) were within 7 days, 7 cases(20.6%) were within 30 days and 3 cases(8.8%) were found over 1 month. 7) In mode of treatment, ventilating bronchoscopic removal under general anesthesia was performed in 29 cases(85.3%), thoracotomy with bronchotomy in 2 cases, thoracotomy with lobectomy in 1 case and postural drainage in 2 cases. 8) Complication rate according to the nature of foreign body was most high in vegetables(68.2%). 9) Correlation between complication rate and the duration of the foreign bodies in situ was definite.

Provably Secure Length-Saving Public-Key Encryption Scheme under the Computational Diffie-Hellman Assumption

Baek, Joon-Sang,Lee, Byoung-Cheon,Kim, Kwang-Jo Electronics and Telecommunications Research Instit 2000 ETRI Journal Vol.22 No.4

Design of secure and efficient public-key encryption schemes under weaker computational assumptions has been regarded as an important and challenging task. As far as ElGamal-type encryption schemes are concerned, some variants of the original ElGamal encryption scheme based on weaker computational assumption have been proposed: Although security of the ElGamal variant of Fujisaki-Okamoto public -key encryption scheme and Cramer and Shoup's encryption scheme is based on the Decisional Diffie-Hellman Assumption (DDH-A), security of the recent Pointcheval's ElGamal encryption variant is based on the Computational Diffie-Hellman Assumption (CDH-A), which is known to be weaker than DDH-A. In this paper, we propose new ElGamal encryption variants whose security is based on CDH-A and the Elliptic Curve Computational Diffie-Hellman Assumption (EC-CDH-A). Also, we show that the proposed variants are secure against the adaptive chosen-ciphertext attack in the random oracle model. An important feature of the proposed variants is length-efficiency which provides shorter ciphertexts than those of other schemes.

부비동염에 속발한 구후신경염 환자에서 시신경 감압술 1예

백병준,김희중,최제환,오천환 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.12