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      • KCI등재

        도시 및 농어촌 지역 거주 청중년 여성 1인가구의 건강수준 특성 비교 연구

        김보람 ( Kim¸ Boram ),이경수 ( Lee¸ Kyung-soo ),정미영 ( Jung¸ Mi-yeong ) 한국도서(섬)학회 2021 韓國島嶼硏究 Vol.33 No.3

        최근 부부와 자녀 중심으로 이루어진 가구 형태는 감소하고 1인가구가 급속하게 증가하고 있다. 1인가구는 라이프 스타일, 삶의 변화 등은 건강에 영향을 미치는 요인 중의 하나이다. 1인가구는 음주, 흡연, 비만 등의 건강생활행태에 있어 다인가구에 비해 상대적으로 위험성이 높은 집단으로 양극화, 고령화, 여성화의 특성을 가진다. 그러므로 이들은 신 건강취약계층으로 건강 사각지대에 놓일 가능성이 높아 향후 이들에 대한 사회경제적 비용이 점차 증가하게 될 것으로 예측하고 있다. 특히 여성 1인가구의 증가는 여성의 빈곤화를 초래할 수 있어 본 연구는 여성 1인가구를 대상으로 농어촌과 도시지역에 따른 두 집단 간의 건강특성을 분석하고자 하였다. 본 연구는 우리나라 청장년층 1인가구 여성들을 대상으로 이들의 건강한 삶에 영향을 주는 요인을 파악하기 위해 질병관리청으로부터 제공받은 2019년 지역사회 건강조사 원시자료를 활용하였다. 연구에 활용된 변수는 사회인구학적 특성, 건강수준 및 건강행태, 의료 이용, 정신건강, 사회적 연결망 및 사회활동 참여를 바탕으로 여성 1인가구의 거주지역에 따른 도시와 농어촌 두 집단 간 비교, 분석을 실시하였다. 여성 1인가구의 건강행태 및 수준을 보면, 청년은 생애주기 중 가장 건강한 시기이므로 농어촌과 도시 간 건강수준에 있어서 유의미한 차이를 보이지 않았으나, 중년의 경우, 주관적 불건강인지율(p<.001), 높은 현재흡연율(p=.013)과 고위험음주율(p=.038)의 불건강행태가 도시에서 높았고, 농어촌은 비만율(p<.001), 아침식사(주5-7회) 비율이 높았다(p=.009). 정신건강은 청년(p=.567)과 중년(p=.149) 모두 도시와 농어촌 두 집단간 스트레스 인지율의 유의미한 차이는 없었으나 우울감 경험율은 청년(p<.001)과 중년(p<.001) 모두 도시가 농어촌보다 높았고 유의미한 차이를 보였다. 사회적연결망 및 참여는 청년의 경우 농어촌이 친척(p<.001), 이웃(p<.001)과의 만남이 도시 보다 유의미하게 높게 나타났고, 사회활동은 친목활동(p=.040), 여가레저활동(p=.036), 자선단체 활동(p<.001)이 농어촌에 비해 도시가 더 활발하였다. 중년의 경우, 친척(p<.001), 이웃(p<.001)과의 만남이 농어촌이 도시보다 유의미하게 높게 나타났고, 사회활동은 종교활동(p=.102), 여가레저활동(p=.145)은 도시에서 높았던 반면 친목활동(p=.381)과 자선단체활동(p=.364)은 농어촌에서 높았으나 유의미한 차이는 없었다. 그 동안 노인 여성 1인가구를 중심으로 이루어진 연구가 많이 이루어져왔던 반면 청중년 여성 1인가구를 바탕으로 한 건강연구는 많이 이루어지고 있지 않았다는 점에서 본 연구의 의의가 있다. 따라서 본 연구결과는 청중년 여성 1인가구의 특성을 분석한 기초자료를 제공하며, 이들의 건강증진 및 유지를 위한 제언을 제시하고자 하였다. Recently, the number of households centered on couples and children has decreased and the number of single-person households has increased rapidly. Single-person households are one of the factors that affect health, such as lifestyle and life changes. Single-person households have the characteristics of polarization, aging, and feminization compared to multi-person households, so single-person households are likely to be in a health blind spot as one of a set of newly identified health vulnerable groups. Among them, the purpose is to analyze the health characteristics between the two main groups according to urban, farming, and fishing areas, especially focusing on single female households. According to the health behavior and level of single-woman households, young people showed no significant difference in health level among urban, farming, and fishing areas, because it is the healthiest time of their lives, but in middle age, subjective poor self-rated health(p<.001), high current smoking rates(p=.013) and high risk drinking rates(p=.038) was high in cities, and farming and fishing areas had an obesity rate of(p<.001), while breakfast consumption(5-7 times a week) rates were high(p=.009). Mental health in young people is(p=.567) and in middle-aged people recorded at(p=.149) There was no significant difference in stress recognition rates among urban, farming, and fishing areas, but both young people(p<.001) and middle-aged folk(p<.001) showed significant differences as cities were higher statistically than farming and fishing areas. Social networks and participation are related to young people in farming and fishing areas(p<.001) and meeting with neighbors(p<.001) were significantly higher than the city, while social activities were social activities(p=.040), leisure activities (p=.036), and charity work(p<.001) was more active in the city than in farming and fishing areas. In middle age, connection to relatives(p<.001) and neighbors(p<.001) was significantly higher than the city, and social activities such as religious activities(p=.102) and leisure activities(p=.145) were higher in the city while social activities(p=.381) and charity work(p=.364) was high in farming and fishing areas, but there was no significant difference. Based on the results of this study, it was intended to propose suggestions for the promotion and maintenance of health according to the characteristics of single female households in the target audience age group according to the region.

      • KCI등재

        한 전자제품 연구소 종사자들의 생활습관 행태와 건강상태의 관련성

        명준표,김형렬,최원선,조성은,이보람,구정완,이강숙,박정일 大韓産業醫學會 2009 대한직업환경의학회지 Vol.21 No.1

        목적 학 전자제품 개발연구소의 근로자들을 대상으로 실시하였던 건강검진 자료를 이용하여 생활습관 상태와 건강상태를 파악하고 이들 사이의 관련성을 조사하고자 하였다 방법 건강검진을 받았던 수검자 3041명을 최종 대상자로 선정하였고 국민건강보험공단에서 제시한 건강검진 문진표 중 식이 음주 몹연 운동 항목을 이용하여 생활습관에 대한 평가를 실시하였다 건강검진결과를 이용하여 비만 혈압 당뇨 간장질환 이상지혈증에 대한 정상/비정상을 평가하였다 건강검진결과와 생활습관에 대한 평가는 다변량 로지스틱 희귀분석을 통하여 실시하였다 결과 조사 대상자의 생활습관 중 과도한 음주의 유병률은 1610명(52.9%) 운동 부족 2662명(86,2%) 흡연 952명(31.3%)이였다 건강검진 결과 비만인 군은 824명(27.1%) 고혈압 군은 198명(6.5%) FBS가 비정상 군은 28명 (0.9%) 간기능 검사 비정상 군은 462명(15.2%) 이상지혈증이 있는 군은 563명(18.5%)의 유병률을 보였다 다별량 로지스틱 희귀분석 결과 육류 위주의 식이는 비만 고혈압 간장질환(ALT r-GTP) 이상지혈증(LDL)과 관련이 유의하게 높았고 과도한 음주는 비만 고혈압 r-GTP 비정상의 위험도와 통계적으로 유의한 관련성이 있었다 운동 부족인 군은 HDL 비정상의 위험도가 높았으며 흡연군은 비만 당뇨 간장질환(ALT r-GTP) 이상지혈증(TG HDL)의 위험도가 통계적으로 유의하게 높았다 결론 전자제품 개발연구소 근로자들의 바르지 않은 생활습관(식이 음주 운동 흡연)은 비만 고혈압 당뇨 간장질환 이상지혈증과 관련이 있다 따라서 연구직 근로자들을 대상으로 한 사업장 건강증진 사업이 필요하다 Background An unhealthy lifestyle is the most important cause of lifestyle-induced illness (diabetes hypertension liver enzyme abnormality dyslipidemia etc) This study was carried out to evaluate that relation between employees lifestyle and their health status in a Korean electronic research and development company Methods We conducted a descriptive cross-sectional survey 3,041 consecutive workers in a Korean R&D company were enrolled in this study A checkup list for the health examination (from the National Health Insurance Coperation) which contained the information on the lifestyle, and the results of the health examination which contained information on the body mass index (BMI) systolic blood pressure (SBP) and diastolic blood pressure (DBP) and liver function tests (LFT AST ALT r-GTP) and Cholesterol profiles (total cholesterol TG, HDL, LDL) were done for all the subjects We evaluated the health profile as normal or abnormal Statistical analysis of the health profiles and the lifestyle of the employees was performing by using multiple logistic regression analysis Results The prevalence of 'excessive alcohol drinking was 52.9% (n=1,610) that for 'lack of exercise' was 86.2% (n=2,662), that for meat eating 12.2% (n=370) and that for current smoker was 31.3% (n=952) According to results of health examination the prevalence of obesity was 27.1%(n=824) hypertension was 7.1% (n=215) diabetes was 1.0% (n=30) abnormal LFT was 15.4% (n=469) and dyslipidemia was 18.7% (n=569) On multiple logistic regression analysis of the health profile and lifestyle 'meat eating' was related to obesity hypertension abnormal LFT (ALT, r-GTP) dyslipidemia (LDL) Excessive alcohol drinking was related to obesity hypertension abnormal LFT (r-GTP) Lack of exercise' was related to dyslipidemia (HDL) Current smoker was related to obesity, diabetes abnormal LFT (ALT r-GTP) and dyslipidemia (TG HDL) with statistically significance Conclusions For workers in the R&D company an unhealthy lifestyle (such as diet alcohol drinking lack of exercise and smoking) were related to obesity hypertension diabetes abnormal LFT and dyslipidemia Therefore health promotion is necessary for the young employees of an Korean R&D company

      • Korean Association for Clinical Oncology : Slide Session ; P-62 : Palliative Cancer ; Longitudinal Change of Quality of Life in Patients Who Experienced Gastric and Colorectal Cancer Surgery

        ( Dae Ro Choi ),( Boram Han ),( Jung Hoon Kim ),( Hyeong Su Kim ),( Geun Doo Jang ),( Jung Hye Kwon ),( Ho Young Kim ),( Jung Han Kim ),( Joo Young Jung ),( Hyo Jung Kim ),( Hyunsook Yoon ),( Hoon Sik 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Early detection of cancer and improved treatment has led to higher survival rates and increased long-term survivors in oncology practice. But there are few longitudinal Quality of Life (QoL) studies in patients who experienced cancer surgery.To investigate the longitudinal change in QoL after cancer surgery, we designed prospective study for QoL in patients who experienced gastric and colorectal cancer surgery. Methods: A prospective longitudinal cohort study was designed. Patients from Hallym, Ajou, and Samsung medical center in South Korea were enrolled from February to September of 2012. They were given questionnaires every 6 months since then, and we`ve been using EORTC QLQ C-30 as quality of life scale. Patients over 55 years old who received curative resection due to gastric or colorectal cancer were included. The mean scores of the patients completing the interview at the 3 time points were compared using mixed model. Results: A total of 273 patients were interviewed at baseline. There were 188 patients (68.9 %) over 65 years old. As expected, physical functioning showed signifi cantly higher score in younger group (< 65 years old) (p=0.008). But global health status score in elderly group (= 65 years old) was higher than in younger (p=0.016). Younger patients complained of diarrhea more (p=0.027). In other items, there were no signifi - cant differences. As time went on, in both age group, appetite was improved, fi nancial diffi culties was increased. In this longitudinal cohort study, the elderly patients who experienced gastric and colorectal cancer surgery maintained relatively well-preserved functional status except physical function, compared with younger patients. And most patients expressed fi nancial burden was increasing as time went on.

      • S-8 Comparison of tenofovir versus entecavir therapy in nucleos(t)ide-naive chronic hepatitis B

        ( Boram Min ),( Joong Gi Bae ),( Hyun Seong Lee ),( Young Min Shin ),( Kyung Hye Park ),( Byung Uk Lee ),( Jae Ho Park ),( Byung Gyu Kim ),( Seok Won Jung ),( In Du Jeong ),( Sung-jo Bang ),( Jung Woo 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

        Backgrounds:?Entecavir (ETV) and tenofovir (TDF) are nucleoside analogues with high potency for profound and durable viral suppression and genetic barriers against resistance; these drugs are recommended for the first-line treatment of chronic hepatitis B (CHB) in current guidelines. But rare data are available on the comparison of TDF and ETV therapy in CHB patients with baseline high viral load (HVL), defined as having hepatitis B virus (HBV) DNA >8 log10 copies/mL (7.3 log10 IU/mL).?Methods:?We performed a retrospective analysis of the efficacy of TDF therapy, as compared to that of ETV therapy, in patients with HVL. A matched study population was constructed to compare the antiviral efficacy of TDF therapy and ETV therapy by a propensity score analysis. The primary endpoint was a virological response (VR), defined as an HBV DNA level of <12 IU/mL.?Results:?Three hundreds two patients were selected after matching propensity score with 1:1 ratio. VR was observed in 66.2% (100/151) of patients in the TDF group and in 63.6% (96/151) of the patients in the ETV group. The VR rates were not different between the two groups (78.1 vs. 76.2% at month 12, and 99.0 vs. 95.8% at month 24; log rank p=0.432). During therapy, 74.8% of patients in the TDF group, and 70.2% of patients in the ETV group had partial VR, respectively (p=0.367). ALT normalization rates also did not differ between both the treatment groups (94.2% and 92.1% in the TDF and ETV therapy groups, respectively; p=0.476). During therapy, 13.7% (18 of 131) of patients in the TDF group, and 21.2% (28 of 132) of patients in the ETV group achieved HBeAg seroconversion, respectively (p=0.111). Nineteen patients experienced a virological breakthrough. Among them, twelve patient (7.9 %) was in the TDF group and 7 patients (4.6 %) were in the ETV group (p=0.236). Conclusions:?In patients with a baseline HBV DNA level >8 log10 copies/mL (7.3 log10 IU/mL), TDF therapy was as effective as ETV therapy, in maintaining the viral suppression.

      • Clinical Characteristics of Pyogenic Liver Abscess; Focusing on Comparison of Primary Pathogens between Escherichia coli and Klebsiella pneumonia

        ( Boram Cha ),( Jung Hwan Lee ),( Hea Yoon Kwon ),( Jung Hwan Yu ),( Young-joo Jin ),( Jin Woo Lee ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: Pyogenic liver abscess (PLA) is a common intra-abdominal infection in adults. However, the clinical influence of primary pathogens of liver abscess on patients has not yet been fully elucidated. We aimed to investigate the clinical features of PLA patients according to the pathogens, such as, Escherichia coli (PLA-EC) or Klebsiella pneumoniae (PLA-KP). Methods: A retrospective review was performed for consecutive 255 PLA patients who admitted to our institute from January 2007 to December 2017. Of these 255 patients, 100 patients were excluded due to definite pathogen (n=63) and the other pathogen rather than Escherichia. coli or Klebsiella pneumonia (n=37). Culture was defined as positive when pathogen was confirmed by blood or aspiration culture. The remaining 155 patients were enrolled in this study, and were dichotomized as two groups of PLA-EC (n=34, 21.9%) and PLA-KP (n=121, 78.1%). Results: The mean age of PLA-EC patients was higher than that of PLA-KP patients (66.5±13.7 vs 60.2±13.2, P=0.016). Gastrointestinal cancer including stomach, liver, or biliary tract was more common in PLA-EC group than PLA-KP group (50.0 vs 18.2 %, P<0.001). Chronic alcoholics (0.0 vs 9.1 %, P=0.068) and diabetes (88.2 vs. 11.28 %, P=0.073) tended to be more frequent in PLA-KP group than PLA-EC group. Anemia (29.4 vs. 9.1 %, P=0.002) and hyperbilirubinemia (58.8 vs. 36.4 %, P=0.019) were found more frequently in PLA-EC than in PLA-KP. The abscess-related mortality in PLA-EC patients was significantly higher than that in PLA-KP patients (7/27, 20.6% vs. 7/114, 5.8%) (P=0.008). Conclusions: Gastrointestinal cancer of stomach, liver, or biliary tract may be associated with PLA-EC. Therefore, these patients require work-up and careful managements, especially in PLA patients who are combined with anemia or jaundice.

      • SCISCIESCOPUS

        A Plant Virus-Based Vector System for Gene Function Studies in Pepper

        Choi, Boram,Kwon, Sun-Jung,Kim, Myung-Hwi,Choe, Siwon,Kwak, Hae-Ryun,Kim, Mi-Kyeong,Jung, Choonkyun,Seo, Jang-Kyun American Society of Plant Biologists 2019 Plant Physiology Vol.181 No.3

        <P>A plant virus-based system enables transient gain- and loss-of-function studies in pepper, a highly recalcitrant species for genetic transformation.</P><P>While pepper (<I>Capsicum annuum</I>) is a highly recalcitrant species for genetic transformation studies, plant virus-based vectors can provide alternative and powerful tools for transient regulation and functional analysis of genes of interest in pepper. In this study, we established an effective virus-based vector system applicable for transient gain- and loss-of-function studies in pepper using <I>Broad bean wilt virus2</I> (BBWV2). We engineered BBWV2 as a dual gene expression vector for simultaneous expression of two recombinant proteins in pepper cells. In addition, we established enhanced and stable expression of recombinant proteins from the BBWV2-based dual vector via coexpression of a heterologous viral suppressor of RNA silencing. We also developed a BBWV2-based virus-induced gene silencing (VIGS) vector, and we successfully silenced the phytoene desaturase gene (<I>PDS</I>) using the BBWV2-based VIGS vector in various pepper cultivars. Additionally, we optimized the BBWV2-based VIGS system in pepper by testing the efficiency of <I>PDS</I> gene silencing under different conditions. This BBWV2-based vector system represents a convenient approach for rapid and simple analysis of gene functions in pepper.</P>

      • KCI등재
      • Convergent synthesis of new types of stabilized carotenoid compounds

        Kim, Soo Bong,Kim, Hyungjun,Lim, Boram,Meang, Juwan,Bae, Sung-Hee,Choi, Eunho,Oh, Jung Taek,Hong, Inseok,Jung, Se-Young,Yeo, Jung Eun,Koo, Sangho De Gruyter 2011 Pure and applied chemistry. Vol.83 No.3

        <P>A convergent synthetic method for new types of carotenoid compounds containing phenyl substituents at C(13) and C(13') has been developed by the coupling of allylic sulfone and 2,7-diphenyloct-4-enedials, followed by the double elimination strategy. These carotenoid compounds are fairly stable and legitimate candidates for nanosized molecular wires, which show diverse conductance values according to the electronic nature of the substituent group in the phenyl ring.</P>

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