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종양(腫瘍)의 전이(轉移) 및 재발(再發) 억제(抑制)에 관(關)한 고찰(考察)
김종대,조종관,Kim, Jong-Dae,Cho, Chong-Kwan 대한한방내과학회 1997 大韓韓方內科學會誌 Vol.18 No.2
Many types of cancer, current therapy other than surgery and/or radiotherapy was of only limited efficacy. At the basic chinese traditional medicine(TCM) there was increased understanding of the additional basic and clinical neoplasm treatment research. The metastasis and recurrence of neoplasm was the basis of yudu(餘毒) on remained neoplasm cell and stagnation of blood, thermotoxo, phlegm, asthenia of healthy enerngy, stagnation of vital energy. The principles therapy of neoplasm on metastasis and recurrence was based on knowledge of the method of support the healthy energy and strengthen the body resistance, promote blood circulation to remove blood stasis, clear away heat and toxic materials, dissipate phlegm and disperse the accumulation of evils, regulate vital energy and disperse the depressed vital energy. But the major clinical features of neoplasm was to be considered in developing a treatment plan include (1) distinguish between clinical and pathologic staging - acute and chronic, (2) classification of pathologic pattern, and (3) distinction of body situation : for examples asthenia - sthenia etc. It was most important to distinguish between supporting the healthy and eliminating the evil factors and to treat differently at the root and the branch cause of a neoplasm. This paper's results indicate that identification and effective use of TCM medicines inhibited netastasis and decreased recurrence and then we were able to expect increasing survival rate.
부정생진탕(扶正生津湯)이 방사선(放射線) 조사(照射) 부작용(副作用)에 미치는 영향(影響)
김종대,조종관,Kim, Jong-Dae,Cho, Chong-Kwan 대한한방내과학회 1998 大韓韓方內科學會誌 Vol.19 No.2
To evaluate the radioprotective effects of Bujeongsaengjintang studies were done experimentally. The results were obtained as follows: 1. WBC, Platelet and RBC were significantly increased in Bujeongsaengjintang treated group as compared with control group after exposure to radiation by Liniac. 2. By FACS analysis of splenic leukocyte after exposure to radiation by Liniac, T cell, T-helper cell and macrophase were significantly increased in Bujeongsaengjintang treated group. 3. In histological changes of ileum and jejunum of Balb/C mice after exposure to radiation by Liniac, exclusion and fusion of villi were decreased in Bujeongsaengjintang treated group as compared with control group. From above results, it is suggested that Bujeongsaengjintang is available to a clinic for the protection from damage by radiotherapy to cancer.
김종대(Chong Dae Kim) 중앙대학교 한국문화유산연구소 2008 중앙민속학 Vol.- No.13
삼국시대의 기록을 보면 돼지는 하늘에 바치는 신성한 제물로 이를 위해 돼지만을 전담해 키우는 관리가 있었다고 하며, 수도와 왕비를 점지하는 신의 뜻을 전달하는 존재로 인식되었던 것으로 보인다. 그런 점에서 돼지는 신의 뜻을 전달한 신성한 존재였음을 알려주는 것이라고 하겠다. 또한 돼지꿈을 꾸게 되면 우리는 복권을 구입한다. 이것은 복권이 맞고 안 맞고를 떠나서 돼지가 복을 상징한다고 믿어온 속신 때문이다. 우리 민족은 그럴 만큼 돼지가 복을 가져다주는 상징적 동물로 생각하여 왔다. 그러나 재물을 가져다준다고 믿는 것과는 달리 돼지의 일상적인 행동을 보고 만들어낸 것이 탐욕과 게으름, 그리고 지저분함의 상징이다. 특히 돼지를 비속하게 표현하는 내용은 대개 속담으로 만들어져 그러한 행동을 하는 사람들을 빈정거릴 때 사용된다. 이렇듯 돼지는 우리 민족에서 긍정과 부정의 양면성이 극명하게 대립된 모습을 보여주는 동물이다. 이처럼 부정과 긍정이 심하게 나타난 동물도 없을 정도로 매우 주목을 받았다. 하지만 현재는 그런 상징성이 긍정적인 면으로 강조되어 나타나고 있는 특징을 보인다. 이러한 사정은 현대사회에서 각 개인들이 추구하고 있는 지향점이 행복 추구나 물질만능주의에 있음을 잘 보여주는 것이라고 하겠다. 이 글에서는 이러한 돼지의 민속상징이 무엇인지, 긍정적인 면과 부정적인 면은 어떻게 표현되어 왔는지 등에 대해 살펴보고자 한다. Pigs have been the animals that show an obvious antagonistic characteristic to our nation which is affirmative or negative. Like this. none of animals has clearly positive and negative aspects except pigs, so they come into notice. However. at this point in time the symbolism has been emphasized on positive sides. This circumstances show that the aim which individuals pursue in this society consists in the pursuit of happiness or materialism. It is not only examine what such pigs's symbolism in folk is also how positive or negative sides have been described and the like.
이익행,김진규,이운석,김주연,김은영,김종대,김수정,Lee, Ik-Haeing,Kim, Jin-Gyu,Lee, Woon-Suk,Kim, Ju-Youn,Kim, Eun-Young,Kim, Chong-Dae,Kim, Soo-Jung 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.2
Ascites is commonly caused by portal vein pressure accentuation or peritoneal disease. Also, the use of diuretic and ascitic puncture have been the mainstays of ascites treatment. Objective : Experimental studies were done to research the effects of herbal medication on diseases with ascites (ex. liver cirrhosis, peritoneal carcinoma) on two patients. Methods : For measuring the response about the ascites, we observed this clinical symptoms : weight, abdominal circumference (umbilical circumference, upper abdominal circumference), and lab finding. Result : In both cases, clinical symptoms and ascites improved with herbal medication. Second, abdominal circumference decreased. Third, there was no electrolyte imbalance. Conclusion : This test shows that herbal medication has a strong effect on decreasing the intractable ascites.
OCX-32 유전자 내 c.494A>C 및 c.267T>G SNP이 한국 재래닭 산란형질에 미치는 효과 분석
이지연,최소영,김종대,홍영호,정동기,이성진,Lee, Ji-Yeon,Choi, So-Young,Kim, Chong-Dae,Hong, Yeong Ho,Jeong, Dong Kee,Lee, Sung-Jin 한국가금학회 2014 韓國家禽學會誌 Vol.41 No.3
가금 사육 프로그램에서 경제적으로 중요한 형질에 잠재적인 후보 유전자의 식별 및 활용은 점점 더 중요해지고 있다. Ovocalyxin-32(OCX-32) 유전자는 닭의 9번 염색체에 위치하며, 난각을 형성하는데 중요한 역할을 한다. 본 연구의 목적은 한국 재래닭의 OCX-32 유전자 내 SNP의 유전자형 결정과 산란 형질과의 연관성을 분석하기 위해 수행하였다. PCR-RFLP 방법을 통해 한국 오골계 46수, 백색 46수, 회색 43수, 흑색 46수를 포함한 총 181수의 한국 재래닭 암컷 4종의 SNP을 분석하였다. 산란 형질은 시산일령, 시산난중, 산란율, 난중의 4가지 항목을 포함하여 측정하였다. OCX-32 유전자 내 c.494A>C SNP은 오골계의 산란율과 유의적인 차이를 나타냈으며(p<0.001), 백색 재래닭에서는 난중과 유의적인 상관관계가 있었다(p<0.05). c.267T>G SNP은 오골계의 난중과 유의적인 연관성이 나타났다(p<0.05). 하지만 회색과 흑색 재래닭에서는 유의적인 상관관계가 나타나지 않았다. 본 연구 결과, 한국 재래닭의 사육 프로그램에서 산란형질을 선발하는 마커로 사용되기까지 추후 더 많은 개체군을 통한 연구가 요구되나, OCX-32 유전자 내 c.494A>C와 c.267T>G의 단일염기변이가 한국 재래닭 중 오골계와 백색 재래닭에서 산란 특성에 따른 DNA 선발 마커로서 활용할 수 있을 것으로 사료된다. The identification and utilization of potential candidate genes with significant effects on economically important traits have become increasingly important in poultry breeding programs. The ovocalyxin-32 (OCX-32) gene is located chromosome 9 in chicken, plays an important role in eggshell formation. This study was performed to assess the association between single nucleotide polymorphisms (SNPs) of OCX-32 gene and egg production traits in the Korean native chicken. Four Korean native chicken population (n = 181; including 46 females of Ogol, 46 females of white, 43 females of gray and 46 females of black) were used to analyze two SNPs (c.494A>C and c.267T>G) in the OCX-32 gene by PCR-RFLP (Polymerase Chain Reaction-Restricted Fragment Length Polymorphism). We measured egg production traits of age at first egg, first egg weight, egg production ratio and egg weight. The SNP c.494A>C was significantly associated with egg production ratio in Korean Ogol chickens (p<0.001) and egg weight in Korean white chickens (p<0.05). SNP c.267T>C was significantly associated with egg weight in Korean Ogol chickens (p<0.05). But there was no significant association in Korean gray and black chickens. Results suggest the possibility of using molecular markers in OCX-32 gene as a tool for performance and egg production traits in Korean native chicken breeding program.
김학규(Hak-Kyu Kim),홍의철(Eui-Chul Hong),강보석(Bo-Seok Kang),김종대(Chong-Dae Kim),허강녕(Kang-Nyeong Heo),추효준(Hyo-Jun Choo),황보종(Jong Hwangbo) 충남대학교 농업과학연구소 2012 농업과학연구 Vol.39 No.1
This work was conducted to evaluate the laying performance of Korean Native Ducks (KND) Pure-Line (PL). A total of 400 female pullets were hatched from PL to keep in National Institute of Animal Science, Korea. Twenty weeks old PL female ducks were divided into 4 groups (5 replications/group, 20 head/replications). Four groups were compared in a 2×2 factorial arrangement with strain (White strains, WW; Celadon strains, CC) and house type (flat house, cage house). On first egg laying day, CC strain laid eggs earlier compared to WW strain (P<0.01), but there was no significant difference between flat and cage house. Egg weight (EW) and body weight (BW) at first egg laying day have no difference among strains and houses. BW of CC strain was higher than WW strain at the age of 30 week (P<0.01). Weekly feed intake (FI) have no difference between flat and cage house, but FI of WW strain was high compared to CC strain during 20~30 weeks. There was no significant difference on EW between CC and WW strains, but EW was low at flat house compared to cage house (P<0.05). Weekly egg productions of WW strain and flat house were lower than CC strain and cage house, respectively (P<0.01). Finally, These results can provide the information that needed to introducing new strains.