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      • KCI등재후보

        근피판을 이용한 흉벽결손의 재건

        최중혁,민경원 대한성형외과학회 2003 Archives of Plastic Surgery Vol.30 No.4

        The chest wall plays a role to protect vital organs in the trunk such as heart and lung, and to facilitate a semi-rigid structure for breathing. When a defect occurs in a chest wall for such reasons as trauma, tumor, infection, inflammation, post-radiation necrosis, congenital anomaly, and so forth, not only anatomical, but also functional aspects should be considered in reconstruction process. It is, generally speaking, difficult to reconstruct a chest wall defect, since these patients tend to be old aged and have underlying disease with chronic and heavily contaminated wounds which had experienced irradiation or operation. In chest wall reconstruction, the authors utilized muscle flaps in trunk to secure a semi-rigid structure, because muscle flaps in trunk are easily accessible, and have reliable blood vessels. We have conducted 42 cases of chest wall reconstruction between Feb, 1996 and Jan, 2003. Except one case, we succeeded in gaining satisfactory results in functional and anatomical aspects. Based on these experiences, we would like to clarify the principles of chest wall reconstruction as below, helping to choose a proper method in the operations. The principles are appropriate debridement, skeletal reconstruction when indicated, coverage of soft tissue with muscle flap and removal of dead spaces.

      • KCI등재후보

        엑시머레이저 근시교정수술 후 각막지형도상의 광학대와 중심이탈 정도에 대한 연구

        최중혁,양홍석,유호민,안재홍,Joong-Hyuk Choi,Hong-Seok Yang,Ho-Min Lew,Jae-Hong Ahn 대한안과학회 2005 대한안과학회지 Vol.46 No.6

        Purpose: To identify factors influencing the ablation center and to evaluate the size of the ablation zone after PRK and LASIK using Technolas 217 C. Methods: This study examined the results of refractive surgery using Technolas 217 C Excimer laser with eye tracking system in 69 eyes, of which 31 underwent PRK and 38 LASIK. The ablation zone and degree of decentration were determined through corneal topography. We divided the eyes into two groups according to the degree of decentration: less than 0.5 mm as the first group, and from 0.5 to 1.0 mm as the second. The ablation zone diameter in topography was compared with the programmed preoperative optical zone. Results: The only factor influencing the ablation center in the PRK group was preoperative spherical equivalent(p=0.016), and no factor influenced the ablation zone in the LASIK group. In both groups, the long axis of the ablation zone was longer than that of the programmed optical zone(p=0.003), while the short axis was shorter (p=0.001). Conclusions: After refractive surgery using Technolas 217 C Excimer laser with eye tracking system, there was no clinically significant decentration. With greater preoperative spherical equivalent, more decentered ablation was noted in the PRK group. The topographical long axis of the ablation zone was longer than that of the programmed ablation zone, while the short axis of the ablation zone was shorter. During refractive surgery, we should be aware of the possibility that the short axis of the postoperative ablation zone may be shorter than that of the programmed preoperative optical zone.

      • KCI등재
      • KCI등재
      • KCI등재후보

        비침습적 돌출귀 교정

        이윤호,최중혁 대한성형외과학회 2003 Archives of Plastic Surgery Vol.30 No.4

        Prominent ear means congenital ear anomaly which has the obtuse conchoscapal angle caused by underdeveloped antihelix and has the larger concha shape than normal. It can be corrected by non-surgical method such as molding process with splint when ear cartilage keep flexibility right after birth and by surgical method with manipulating the ear cartilage directly. To correct prominent ear, we used simple and effective technique consisted of (1)anterior cartilage surface scoring and (2)two horizontal mattress suture without skin excision because we have the opinion that the most important deformity in prominent ear is lesser projection of antihelical fold. From March 1998 to February 2003 this method was applied to 12 patients. During the follow-up period no particular side effects were detected and we had an excellent aesthetic result.

      • KCI등재

        항혈소판제와 비스테로이드성소염진통제의 동시 투약으로 인한 출혈 사례

        서정민,최중혁,손병우,이승민,채현우,강근형,지은희 한국임상약학회 2018 한국임상약학회지 Vol.28 No.3

        When stenting is applied to treat myocardial infarction, antiplatelet agents are administered to prevent thrombosis, which increases the risk of bleeding. Patients with myocardial infarction are also more likely to have osteoarthritis simultaneously, because both diseases occur frequently in elderly patients. Patients with osteoarthritis often use analgesics, especially nonsteroidal antiinflammatory drugs (NSAIDs); hence, patients with both diseases use analgesics and antiplatelet agents simultaneously. The risk of bleeding increases with the use of antiplatelet agents and this is further increased when NSAIDs are added. We would like to report a case that reflects this situation. A 60-year-old man underwent stenting after ST-elevation myocardial infarction, and was treated with aspirin and clopidogrel. This patient also received a pelubiprofen prescription from another physician to treat osteoarthritis. After the patient took pelubiprofen twice, he found a bruise on his wrist and reported it to the pharmacist. It is unlikely that this is rare in community pharmacies, so pharmacists should pay careful attention to the concomitant administration of analgesics to patients receiving antiplatelet agents and should provide appropriate education to patients.

      • KCI등재

        Oseltamivir 복용 이후 소아에서 발생한 이상행동 및 그 인과성 평가

        손병우,최중혁,이승민,박선순,최은경,유봉규,지은희 한국임상약학회 2019 한국임상약학회지 Vol.29 No.1

        Oseltamivir is an antiviral medication prescribed to prevent and treat influenza A and B. A case from a community pharmacy in Korea was reported for an adverse event associated with oseltamivir administration. A 20-month-old boy had psychiatric symptoms after receiving 2 doses of oseltamivir. Therefore, an evaluation of whether the psychiatric symptoms were caused by oseltamivir was required. To determine whether the adverse event resulted from the administrated medication or other factors, three tools were used: the Naranjo scale, the Korean causality assessment algorithm (Ver.2), and the World Health Organization-Uppsala Monitoring Center (WHO-UMC) criteria. The psychiatric symptoms occurred after oseltamivir administration, and were attenuated after oseltamivir termination. A possible cause of the psychiatric symptoms is high fever, but information on the body temperature of the patient was not sufficient. Therefore, it was unclear whether there were other nonpharmacological causes of adverse drug reaction. For these reasons, in terms of causality, the results evaluated by the three tools represented, "possible", "probable", and "probable/ likely", respectively.

      • KCI등재후보

        눈꺼풀과 안와 주변에 발생한 괴사성 근막염 1예

        김수영,최중혁,문상호,장윤희,장재우 대한안과학회 2004 대한안과학회지 Vol.45 No.1

        Purpose: Necrotizing fasciitis is an uncommon soft tissue infection which spreads rapidly along subcutaneous fascial planes and produces overlying skin necrosis. We report a case of eyelid necrosis and periorbital necrotizing fasciitis. Methods: A 64-year-old, previously healthy, male visited the emergency room complaining of acute facial edema. He had been using an ointment for itchy scalp lesion due to hair dye, and had multiple mosquito bites on his forehead. He took NSAIDs before the day of visit for headache. Physical examination showed erythematous swelling of soft tissue and tense fluctuant bullae on eyelid and periorbital area. On the 6th day of hospitalization bullae ruptured, and purplish discoloration and necrosis were noticed. Results: Parenteral antibiotics and surgical debridement were applied. Wound cultures were positive for Staphylococcus aureus resistant to methicillin. Histology of the debrided tissue showed necrotizing inflammation. The full-thickness skin graft was performed over the exposed pretarsal and preseptal orbicularis muscle of the right eyelid. The skin defects were healed with the recovery of adequate eyelid function. Conclusions: We achieved satisfactory results with proper diagnosis and management such as parenteral antibiotics and surgical debridement in a case with eyelid and periorbital necrotizing fasciitis. 목적 : 괴사성 근막염은 외상, 수술 후 발생한 감염으로 인해 근막 및 피하 연부 조직을 따라 수 일만에 그 범위가 광범위하게 진행되며, 이차적 피부괴사가 동반 발생되는 질환이다. 저자들은 눈꺼풀과 안와 주변의 괴사성 근막염 1예를 경험하였기에 보고하는 바이다. 대상과 방법 : 당뇨병 등 과거력 상 특이사항이 없었던 64세 남자가 머리염색 후 두피의 가려움, 진물 등으로 치료 받던 중, 모기에 이마 부위를 많이 물리고 나서 발생한 두통으로 '판피린과 사리돈'을 복용한 후, 얼굴 전체의 부종이 발생하여 내원하였다. 양안 눈꺼풀과 안와 주변에 홍반성 부종과 수포가 발생했으며, 내원 6일째부터 수포가 터진 부위에 피부괴사가 발생하였다. 결과 : 병변 부위의 분비물 배양 검사 상 메티실린 내성 황색포도상구균(MRSA)이, 조직 생검상 ‘괴사성 염증’ 소견이 관찰되었으며 전신적 항생제 투여와 괴사 조직의 외과적 제거를 반복적으로 시행한 결과, 좌안은 자연 치유가 이루어졌으며, 괴사부위가 더 넓었던 우안은 전층 피부 이식술을 추가하여 눈꺼풀 기능이 비교적 잘 보존되는 결과를 얻을 수 있었다. 결론 : 괴사성 근막염의 적절한 진단을 통해 항생제 투여와 외과적 치료로써 양호한 결과를 얻을 수 있었다.

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