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- 저자 : 장철순(Cheol Soon Jang) (검색결과 3 건)
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알코올 중독자 및 장기 입원 환자에서 thiamine 결핍의 빈도
장철순(Cheol Soon Jang),서동범(Dong Bum Seo),박우상(Woo Sang Park),김일권(Il Kwon Kim),정정환(Chung Hwan Chung),이주희(Ju Hee Lee),이경오(Kyoung O Lee),채민병(Min Byoung Chae),박현민(Hyun Min Park),서영환(Young Hwan Seo),이선영(Sun Y 대한내과학회 2002 대한내과학회지 Vol.62 No.1
N/A Background: As socioeconomic status has improved, malnutrition has become rare in Korea and generally it is no longer considered as a serious problem in medical practice. However, contrary to the above general belief we managed four patients with beriberi in 1999 and it became apparent that malnutrition might remain a problem in certain groups of patients. In this study, we assessed the nutritional state, especially with respect to thiamine deficiency, in chronic alcoholics and in patients residing at a long-term care facility (LTCF). Methods: Fourteen chronic alcoholic patients and twenty patients being hospitalized in a long-term care facility were assigned as the study groups. The subjects mean ages and standard deviations were 48.9±10.2 and 50.6±6.7, respectively. Medical records were reviewed t o determine other aspect s of their nutritional status and their dietary patterns. Ten peoples who visited the health promotion center at Inha University Hospital, for routine check- ups were allocated to the control group. Blood total thiamine levels were measured by high-performance liquid chromatography. Results: Body mass indices were significantly lower in chronic alcoholics and in patients at the LTCF than in the control group (p=0.0065). Serum albumin levels were within the reference range in all three groups, but were significantly lower in patients at the LT CF than in the control group (p =0.0013). Moreover no difference was detected between the alcoholic group and the control group in terms of thiamine levels. However, the mean thiamine level in patients at the LTCF was statistically lower than that of the control group and four (20%) patients in the LTCF group showed subnormal blood thiamine levels. The thiamine level tended t o decrease with age in both alcoholics and patient s at the LT CF. No correlation was found between thiamine level and the other variables examined, namely, hospital stay, body mass index, and serum albumin level. Conclusion: A consider able portion of patients in a long term care facility showed thiamine deficiency, however, no evidence of thiamine deficiency was found among alcoholics. This result suggest s that thiamine deficiency in patient s at long- term care facility may be more prevalent and that thiamine supplementation may be warranted, especially for those with other thiamine deficiency risk factors.(Korean J Med 62:69-76, 2002)
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변태근(Tae-Geun Byun),장철순(Cheol-Soon Jang),김석윤(Seok-Yun Kim),최성환(Sung-Hwan Choi),이상호(Sang-Ho Lee) 한국콘텐츠학회 2022 한국콘텐츠학회논문지 Vol.22 No.1
본 연구의 목적은 외부경제요인을 고려할 수 있는 새로운 산업용지 수요예측 방법을 제시하는 것이다. 분석모형은 외생변수를 고려할 수 있는 ARIMA-X를 이용하였다. 외생변수는 경제 및 산업구조를 반영할 수 있도록 거시경제, 제조업 경기실사지수 및 경기종합지수 변수들로 구성된다. 그리고 예측은 외생변수 중 산업용지 공급보다 선행하는 변수만을 사용한다. 산업용지 공급에 선행성을 갖는 변수는 수입액, 민간·정부소비지출, 총자본 형성, 경제심리지수, 기계류내수출하지수, 경기종합선행지수로 나타났다. 이들 변수를 이용하여 ARIMA-X 모형을 추정한 결과, 수입액 변수만 포함된 ARIMA-X(1,1,0) 모형이 통계적으로 유의한 것으로 나타났다. 산업용지 수요예측은 수입액의 변화 시나리오를 반영하여 2021년부터 2030년까지의 산업용지를 예측하였다. 그 결과, 장래 산업용지 수요는 연평균 1.91% 증가한 1,030.79 ㎢로 예측되었다. 이 결과를 기존 지수평활법과 비교한 결과, 본 연구의 결과가 기존 모형보다 예측오차가 더 적게 나타났다. 새로운 산업용지 예측모형으로 사용가능할 것으로 기대된다. The purpose of this study is to present a new industrial land demand prediction method that can consider external economic factors. The analysis model used ARIMA-X, which can consider exogenous variables. Exogenous variables are composed of macroeconomic variable, Business Survey Index, and Composite Economic Index variables to reflect the economic and industrial structure. And, among the exogenous variables, only variables that precede the supply of industrial land are used for prediction. Variables with precedence in the supply of industrial land were found to be import, private and government consumption expenditure, total capital formation, economic sentiment index, producer’s shipment index, machinery for domestic demand and composite leading index. As a result of estimating the ARIMA-X model using these variables, the ARIMA-X(1,1,0) model including only the import was found to be statistically significant. The industrial land demand forecast predicted the industrial land from 2021 to 2030 by reflecting the scenario of change in import. As a result, the future demand for industrial land was predicted to increase by 1.91% annually to 1,030.79 ㎢. As a result of comparing these results with the existing exponential smoothing method, the results of this study were found to be more suitable than the existing models. It is expected to b available as a new industrial land forecasting model.
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이지영,강재승,김미경,황태숙,곽이경,채민병,장철순,김일권,서동범,정문현 대한감염학회 2001 감염 Vol.33 No.5
Background : Cat scratch disease (CSD) is an emerging disease worldwide and is mainly caused by Bartonella henselae, a gram-negative bacterium. The most common clinical manifestation is regional lymphadenopathy, though clinical recognition may be difficult, as atypical manifestations occur. The condition can be complicated by neuroretinitis, endocarditis, and sometimes fatal encephalopathy. The reservoir of B. henselae is the cat, and the prevalence rates of B. henselae infection in cat populations range from 4 to 70% . The prevalence of Bartonella infection in Korea has not been studied, thus, in this study Bartonella infection was investigated in cats captured in the Inchon and Ansan areas. Methods : Twenty wild cats were captured and their livers and spleens were examined by polymerase chain reaction (PCR), bacterial culture, and histopathologically, PCR used two primers : Cat (sense : 5'-GAT TCA ATT GGT TTG AA(G/A) GAG GCT-3', antisense : 5'-TCA CAT CAC CAG G(A/G)C GTA TTC-3') and Barto (sense:5'-(C/T) CT TCG TTT CTC TTT CTT CA-3', antisense : 5'-AAC CAA CTG AGC TAC AAG CC-3'). Culture was performed by inoculating sliced spleen and liver into the ECV304 cell line and bacterial growth was observed over a period of 3 weeks. If no visible bacterial growth was identified, the presence of bartonella was examined by DNA staining, indirect immunofluorescent staining, and PCR. Liver and spleen were stained with H&E and scrutinized under the light microscope. Results : Nine pairs of culture cells inoculated with liver and spleen were examined by indirect immunofluorescent staining and PCR; no positive case was found. In addition, no positive case was identified by PCR in the liver and spleen specimens of eleven cats. Spleen and liver specimens of eleven cats were examined by light microscopy and none showed granuloma. Conclusion : This preliminary study suggests that the Bartonella infection is probably uncommon in the cat population of the Inchon and Ansan areas. Further studies should be undertaken to detail the prevalence of Bartonella infection in other areas and in human. (Korean J Infect Dis 33:319∼324, 2001)
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